Afshin Samali
Active 1996–2025
- 85
- Papers
- 24,135
- Citations
- 73
- h-index
- 83
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology57.1%
- Medicine27.5%
- Immunology and Microbiology3.6%
- Neuroscience3%
- Agricultural and Biological Sciences2.7%
- Environmental Science1.5%
- Other4.6%
Topics
- Endoplasmic Reticulum Stress and Disease10.8%
- Autophagy in Disease and Therapy6.4%
- Mitochondrial Function and Pathology2.9%
- Cell death mechanisms and regulation2.8%
- Heat shock proteins research2.4%
- RNA regulation and disease1.8%
- Other72.9%
Coauthors
- Adrienne M. Gorman29
- Susan E. Logue16
- Éric Chevet12
- Éva Szegezdi12
- Katarzyna Mnich11
- Sten Orrenius11
- Sandra Healy9
- Sanjeev Gupta9
- John B. Patterson8
- Leif A. Eriksson7
- Richard Jäger7
- Boris Zhivotovsky5
- Chetan Chintha5
- Claudio Hetz5
- Dean P. Jones5
- Patrizia Agostinis5
- Saeid Ghavami5
- Shane Deegan5
- Aitor Almanza4
- Antonio Carlesso4
- Aristotelis Chatziioannou4
- Eoghan P. McGrath4
- Svetlana Saveljeva4
- Timothy O’Brien4
All papers
- The integrated stress response
Authors: Karolina Pakos‐Zebrucka, Izabela Koryga, Katarzyna Mnich, Mila Ljujić, Afshin Samali, Adrienne M. Gorman - EMBO Reports 2016 cited by 2,646
- Endoplasmic reticulum stress signalling – from basic mechanisms to clinical applications
Authors: Aitor Almanza, Antonio Carlesso, Chetan Chintha, Stuart Creedican, Dimitrios Doultsinos, Brian Leuzzi, Andreia Luís, Nicole McCarthy, Luigi Montibeller, Sanket More, Alexandra Papaioannou, Franziska Püschel, Maria Livia Sassano, Josip Skoko, Patrizia Agostinis, Jackie de Belleroche, Leif A. Eriksson, Simone Fulda, Adrienne M. Gorman, Sandra Healy, Andrey V. Kozlov, Cristina Muñoz‐Pinedo, Markus Rehm, Éric Chevet, Afshin Samali - FEBS Journal 2018 cited by 1,017
- PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress
Authors: Tom Verfaillie, Noemí Rubio, Abhishek D. Garg, Geert Bultynck, Rosario Rizzuto, J-P Decuypere, Jacques Piette, Chris Linehan, Sanjeev Gupta, Afshin Samali, Patrizia Agostinis - Cell Death and Differentiation 2012 cited by 838
- Cellular Stress Responses: Cell Survival and Cell Death
Authors: Simone Fulda, Adrienne M. Gorman, Osamu Hori, Afshin Samali - International Journal of Cell Biology 2010 cited by 1,522
- Mediators of endoplasmic reticulum stress‐induced apoptosis
Authors: Éva Szegezdi, Susan E. Logue, Adrienne M. Gorman, Afshin Samali - EMBO Reports 2006 cited by 2,353
- The eIF2α kinases: their structures and functions
Authors: Neysan Donnelly, Adrienne M. Gorman, Sanjeev Gupta, Afshin Samali - Cellular and Molecular Life Sciences 2013 cited by 850
- The role of the unfolded protein response in cancer progression: From oncogenesis to chemoresistance
Authors: Emma C. Madden, Susan E. Logue, Sandra Healy, Serge N. Manié, Afshin Samali - Biology of the Cell 2018 cited by 389
- Regulation of lipid metabolism by the unfolded protein response
Authors: Matthieu Moncan, Katarzyna Mnich, Arnaud Blomme, Aitor Almanza, Afshin Samali, Adrienne M. Gorman - Journal of Cellular and Molecular Medicine 2021 cited by 193
- Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy
Authors: Susan E. Logue, Eoghan P. McGrath, Patricia A. Cleary, Stephanie Greene, Katarzyna Mnich, Aitor Almanza, Éric Chevet, Róisín M. Dwyer, Anup Mammen Oommen, Patrick Legembre, Florence Godey, Emma C. Madden, Brian Leuzzi, Joanna Obacz, Qingping Zeng, John B. Patterson, Richard Jäger, Adrienne M. Gorman, Afshin Samali - Nature Communications 2018 cited by 290
- The ER Stress Sensor PERK Coordinates ER-Plasma Membrane Contact Site Formation through Interaction with Filamin-A and F-Actin Remodeling
Authors: Alexander R. van Vliet, Francesca Giordano, Sarah Gerlo, Inmaculada Segura, Sofie Van Eygen, Geert Molenberghs, Susana Rocha, Audrey Houcine, Rita Derua, Tom Verfaillie, Jeroen Vangindertael, Herlinde De Keersmaecker, Etienne Waelkens, Jan Tavernier, Johan Hofkens, Wim Annaert, Peter Carmeliet, Afshin Samali, Hideaki Mizuno, Patrizia Agostinis - Molecular Cell 2017 cited by 225
- ER stress in obesity pathogenesis and management
Authors: Amir Ajoolabady, Simin Liu, Daniel J. Klionsky, Gregory Y.H. Lip, Jaakko Tuomilehto, Sina Kavalakatt, David M. Pereira, Afshin Samali, Jun Ren - Trends in Pharmacological Sciences 2021 cited by 109
- Endoplasmic Reticulum Stress–Activated Cell Reprogramming in Oncogenesis
Authors: Éric Chevet, Claudio Hetz, Afshin Samali - Cancer Discovery 2015 cited by 368
- Stress management at the ER: Regulators of ER stress-induced apoptosis
Authors: Adrienne M. Gorman, Sandra Healy, Richard Jäger, Afshin Samali - Pharmacology & Therapeutics 2012 cited by 399
- Tumour Cell Secretome in Chemoresistance and Tumour Recurrence
Authors: Emma C. Madden, Adrienne M. Gorman, Susan E. Logue, Afshin Samali - Trends in cancer 2020 cited by 156
- Regulated IRE1α-dependent decay (RIDD)-mediated reprograming of lipid metabolism in cancer
Authors: Aitor Almanza, Katarzyna Mnich, Arnaud Blomme, Claire M. Robinson, Giovanny Rodriguez Blanco, Sylwia Kierszniowska, Eoghan P. McGrath, Matthieu Le Gallo, Eleftherios Pilalis, Johannes V. Swinnen, Aristotelis Chatziioannou, Éric Chevet, Adrienne M. Gorman, Afshin Samali - Nature Communications 2022 cited by 81
- Dual IRE1 RNase functions dictate glioblastoma development
Authors: Stéphanie Lhomond, Tony Avril, Nicolas Dejeans, Konstantinos Voutetakis, Dimitrios Doultsinos, Mari McMahon, Raphaël Pineau, Joanna Obacz, Olga Papadodima, Florence Jouan, Héloïse Bourien, Marianthi Logotheti, Gwénaële Jégou, Néstor Pallares‐Lupon, Kathleen Schmit, Pierre‐Jean Le Reste, Amandine Etcheverry, Jean Mosser, Kim Barroso, Élodie Vauléon, Marion Maurel, Afshin Samali, John B. Patterson, Olivier Pluquet, Claudio Hetz, Véronique Quillien, Aristotelis Chatziioannou, Éric Chevet - EMBO Molecular Medicine 2018 cited by 170
- Crosstalk between inflammatory mediators and endoplasmic reticulum stress in liver diseases
Authors: J. Catharina Duvigneau, Andreia Luís, Adrienne M. Gorman, Afshin Samali, Doris Kaltenecker, Richard Moriggl, Andrey V. Kozlov - Cytokine 2018 cited by 86
- Local intracerebral inhibition of IRE1 by MKC8866 sensitizes glioblastoma to irradiation/chemotherapy in vivo
Authors: Pierre‐Jean Le Reste, Raphaël Pineau, Konstantinos Voutetakis, Juhi Samal, Gwénaële Jégou, Stéphanie Lhomond, Adrienne M. Gorman, Afshin Samali, John B. Patterson, Qingping Zeng, Abhay Pandit, Marc Aubry, Nicolas Soriano, Amandine Etcheverry, Aristotelis Chatziioannou, Jean Mosser, Tony Avril, Éric Chevet - Cancer Letters 2020 cited by 82
- Simvastatin Induces Unfolded Protein Response and Enhances Temozolomide-Induced Cell Death in Glioblastoma Cells
Authors: Sanaz Dastghaib, Shahla Shojaei, Zohreh Mostafavi‐Pour, Pawan Sharma, John B. Patterson, Afshin Samali, Pooneh Mokarram, Saeid Ghavami - Cells 2020 cited by 74
- Triggering and modulation of apoptosis by oxidative stress
Authors: Joya Chandra, Afshin Samali, Sten Orrenius - Free Radical Biology and Medicine 2000 cited by 1,329
- Redox regulation of UPR signalling and mitochondrial ER contact sites
Authors: Jose C. Casas-Martinez, Afshin Samali, Brian McDonagh - Cellular and Molecular Life Sciences 2024 cited by 58
- Inhibition of IRE1α RNase activity reduces NLRP3 inflammasome assembly and processing of pro-IL1β
Authors: Aaron Talty, Shane Deegan, Mila Ljujić, Katarzyna Mnich, Serika D. Naicker, Dagmar Quandt, Qingping Zeng, John B. Patterson, Adrienne M. Gorman, Matthew D. Griffin, Afshin Samali, Susan E. Logue - Cell Death and Disease 2019 cited by 53
- Caspase‐12 and ER‐Stress‐Mediated Apoptosis
Authors: Éva Szegezdi, Una FitzGerald, Afshin Samali - Annals of the New York Academy of Sciences 2003 cited by 506
- Glioblastoma and chemoresistance to alkylating agents: Involvement of apoptosis, autophagy, and unfolded protein response
Authors: Sabine Hombach‐Klonisch, Maryam Mehrpour, Shahla Shojaei, Craig Harlos, Marshall Pitz, Ahmed Hamaï, Krzysztof Siemianowicz, Wirginia Likus, Emilia Wiecheć, Brian Toyota, Reyhane Hoshyar, Amir Seyfoori, Zahra Sepehri, Sudharsana Rao Ande, Forough Khadem, Mohsen Akbari, Adrienne M. Gorman, Afshin Samali, Thomas Klonisch, Saeid Ghavami - Pharmacology & Therapeutics 2017 cited by 320
