Amy J. Johnson
Active 1978–2025
- 73
- Papers
- 18,930
- Citations
- 59
- h-index
- 71
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine64.8%
- Biochemistry, Genetics and Molecular Biology26.9%
- Immunology and Microbiology4%
- Chemistry1.7%
- Neuroscience0.7%
- Computer Science0.6%
- Other1.3%
Topics
- Chronic Lymphocytic Leukemia Research15.2%
- Lymphoma Diagnosis and Treatment10%
- CAR-T cell therapy research4.5%
- Protein Degradation and Inhibitors3.9%
- Immunodeficiency and Autoimmune Disorders3.6%
- Chronic Myeloid Leukemia Treatments3%
- Other59.8%
Coauthors
- John C. Byrd54
- Jeffrey A. Jones20
- Jennifer A. Woyach20
- Kristie A. Blum18
- Lisa L. Smith17
- Joseph M. Flynn15
- Leslie A. Andritsos15
- Nyla A. Heerema15
- Michael R. Grever14
- Kami J. Maddocks13
- Gerard Lozanski11
- Natarajan Muthusamy10
- Rosa Lapalombella10
- Amy Lehman9
- Amy S. Ruppert9
- David Lucas9
- Richard R. Furman9
- Samantha Jaglowski9
- Weiqiang Zhao9
- Xiaoli Zhang9
- Danelle F. James8
- Sarah E. M. Herman8
- Thomas S. Lin8
- Ahmed Hamdy7
All papers
- Resistance Mechanisms for the Bruton's Tyrosine Kinase Inhibitor Ibrutinib
Authors: Jennifer A. Woyach, Richard R. Furman, Ta-Ming Liu, Hatice Gülçin Özer, Marc Zapatka, Amy S. Ruppert, Ling Xue, Daniel Hsieh-Hsin Li, Susanne Steggerda, Matthias Versele, Sandeep S. Davé, Jenny Zhang, Ayse Selen Yilmaz, Samantha Jaglowski, Kristie A. Blum, Arletta Lozanski, Gerard Lozanski, Danelle F. James, Jacqueline C. Barrientos, Peter Lichter, Stephan Stilgenbauer, Joseph J. Buggy, Betty Chang, Amy J. Johnson, John C. Byrd - New England Journal of Medicine 2014 cited by 1,254
- Targeting the C481S Ibrutinib-Resistance Mutation in Bruton’s Tyrosine Kinase Using PROTAC-Mediated Degradation
Authors: Alexandru D. Buhimschi, Haley A. Armstrong, Momar Toure, Saul Jaime‐Figueroa, Timothy L. Chen, Amy M. Lehman, Jennifer A. Woyach, Amy J. Johnson, John C. Byrd, Craig M. Crews - Biochemistry 2018 cited by 372
- Targeting BTK with Ibrutinib in Relapsed Chronic Lymphocytic Leukemia
Authors: John C. Byrd, Richard R. Furman, Steven Coutré, Ian W. Flinn, Jan A. Burger, Kristie A. Blum, Barbara Grant, Jeff P. Sharman, Morton Coleman, William G. Wierda, Jeffrey A. Jones, Weiqiang Zhao, Nyla A. Heerema, Amy J. Johnson, Juthamas Sukbuntherng, Betty Chang, Fong Clow, Eric Hedrick, Joseph J. Buggy, Danelle F. James, Susan O’Brien - New England Journal of Medicine 2013 cited by 2,249
- BTKC481S-Mediated Resistance to Ibrutinib in Chronic Lymphocytic Leukemia
Authors: Jennifer A. Woyach, Amy S. Ruppert, Daphne Guinn, Amy Lehman, James S. Blachly, Arletta Lozanski, Nyla A. Heerema, Weiqiang Zhao, Joshua F. Coleman, Daniel Jones, Lynne V. Abruzzo, Amber Gordon, Rose Mantel, Lisa L. Smith, Samantha McWhorter, Melanie E. Davis, Tzyy-Jye Doong, Fan Ny, Margaret S. Lucas, Weihong Chase, Jeffrey A. Jones, Joseph M. Flynn, Kami J. Maddocks, Kerry A. Rogers, Samantha Jaglowski, Leslie A. Andritsos, Farrukh T. Awan, Kristie A. Blum, Michael R. Grever, Gerard Lozanski, Amy J. Johnson, John C. Byrd - Journal of Clinical Oncology 2017 cited by 471
- Acalabrutinib (ACP-196) in Relapsed Chronic Lymphocytic Leukemia
Authors: John C. Byrd, Bonnie K. Harrington, Susan O’Brien, Jeffrey A. Jones, Anna Schuh, Steve Devereux, Jorge Chaves, William G. Wierda, Farrukh T. Awan, Jennifer R. Brown, Peter Hillmen, Deborah M. Stephens, Paolo Ghia, Jacqueline C. Barrientos, John M. Pagel, Jennifer A. Woyach, Dave Johnson, Jane Huang, Xiaolin Wang, Allard Kaptein, Brian J. Lannutti, Todd Covey, Maria Fardis, Jesse McGreivy, Ahmed Hamdy, Wayne Rothbaum, Raquel Izumi, Thomas G. Diacovo, Amy J. Johnson, Richard R. Furman - New England Journal of Medicine 2015 cited by 891
- Ibrutinib is an irreversible molecular inhibitor of ITK driving a Th1-selective pressure in T lymphocytes
Authors: Jason A. Dubovsky, Kyle A. Beckwith, Gayathri Natarajan, Jennifer A. Woyach, Samantha Jaglowski, Yiming Zhong, Joshua Hessler, Ta-Ming Liu, Betty Chang, Karilyn M. Larkin, Matthew Stefanovski, Danielle L. Chappell, Frank Frissora, Lisa L. Smith, Kelly A. Smucker, Joseph M. Flynn, Jeffrey A. Jones, Leslie A. Andritsos, Kami J. Maddocks, Amy M. Lehman, Richard R. Furman, Jeff P. Sharman, Anjali Mishra, Michael A. Caligiuri, Abhay R. Satoskar, Joseph J. Buggy, Natarajan Muthusamy, Amy J. Johnson, John C. Byrd - Blood 2013 cited by 796
- Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765
Authors: Sarah E. M. Herman, Amber Gordon, Erin Hertlein, Asha Ramanunni, Xiaoli Zhang, Samantha Jaglowski, Joseph M. Flynn, Jeffrey J. Jones, Kristie A. Blum, Joseph J. Buggy, Ahmed Hamdy, Amy J. Johnson, John C. Byrd - Blood 2011 cited by 791
- DNA Origami Nanostructures Elicit Dose‐Dependent Immunogenicity and Are Nontoxic up to High Doses In Vivo
Authors: Christopher R. Lucas, Patrick D. Halley, Amjad A. Chowdury, Bonnie K. Harrington, Larry Beaver, Rosa Lapalombella, Amy J. Johnson, Erin Hertlein, Mitch A. Phelps, John C. Byrd, Carlos E. Castro - Small 2022 cited by 103
- Etiology of Ibrutinib Therapy Discontinuation and Outcomes in Patients With Chronic Lymphocytic Leukemia
Authors: Kami J. Maddocks, Amy S. Ruppert, Gerard Lozanski, Nyla A. Heerema, Weiqiang Zhao, Lynne V. Abruzzo, Arletta Lozanski, Melanie E. Davis, Amber Gordon, Lisa L. Smith, Rose Mantel, Jeffrey A. Jones, Joseph M. Flynn, Samantha Jaglowski, Leslie A. Andritsos, Farrukh T. Awan, Kristie A. Blum, Michael R. Grever, Amy J. Johnson, John C. Byrd, Jennifer A. Woyach - JAMA Oncology 2015 cited by 576
- Ibrutinib enhances chimeric antigen receptor T-cell engraftment and efficacy in leukemia
Authors: Joseph A. Fraietta, Kyle A. Beckwith, Prachi Patel, Marco Ruella, Zhaohui Zheng, David M. Barrett, Simon F. Lacey, J. Joseph Melenhorst, Shannon E. McGettigan, Danielle Cook, Changfeng Zhang, Jun Xu, Priscilla Do, Jessica Hulitt, Sagar B. Kudchodkar, Alexandria P. Cogdill, Saar Gill, David L. Porter, Jennifer A. Woyach, Meixiao Long, Amy J. Johnson, Kami J. Maddocks, Natarajan Muthusamy, Bruce L. Levine, Carl H. June, John C. Byrd, Marcela V. Maus - Blood 2016 cited by 461
- Ibrutinib treatment improves T cell number and function in CLL patients
Authors: Meixiao Long, Kyle A. Beckwith, Priscilla Do, Bethany L. Mundy-Bosse, Amber Gordon, Amy M. Lehman, Kami J. Maddocks, Carolyn Cheney, Jeffrey A. Jones, Joseph M. Flynn, Leslie A. Andritsos, Farrukh T. Awan, Joseph A. Fraietta, Carl H. June, Marcela V. Maus, Jennifer A. Woyach, Michael A. Caligiuri, Amy J. Johnson, Natarajan Muthusamy, John C. Byrd - Journal of Clinical Investigation 2017 cited by 377
- Chronic lymphocytic leukemia T cells show impaired immunological synapse formation that can be reversed with an immunomodulating drug
Authors: Alan G. Ramsay, Amy J. Johnson, Abigail M. Lee, Güllü Görgün, Rifca Le Dieu, William Blum, John C. Byrd, John G. Gribben - Journal of Clinical Investigation 2008 cited by 594
- Hypermorphic mutation of phospholipase C, γ2 acquired in ibrutinib-resistant CLL confers BTK independency upon B-cell receptor activation
Authors: Ta-Ming Liu, Jennifer A. Woyach, Yiming Zhong, Arletta Lozanski, Gerard Lozanski, Shuai Dong, Ethan Strattan, Amy Lehman, Xiaoli Zhang, Jeffrey A. Jones, Joseph M. Flynn, Leslie A. Andritsos, Kami J. Maddocks, Samantha Jaglowski, Kristie A. Blum, John C. Byrd, Jason A. Dubovsky, Amy J. Johnson - Blood 2015 cited by 174
- The B-cell receptor signaling pathway as a therapeutic target in CLL
Authors: Jennifer A. Woyach, Amy J. Johnson, John C. Byrd - Blood 2012 cited by 409
- Three-year follow-up of treatment-naïve and previously treated patients with CLL and SLL receiving single-agent ibrutinib
Authors: John C. Byrd, Richard R. Furman, Steven Coutré, Jan A. Burger, Kristie A. Blum, Morton Coleman, William G. Wierda, Jeffrey A. Jones, Weiqiang Zhao, Nyla A. Heerema, Amy J. Johnson, Yun Shaw, Elizabeth Bilotti, Cathy Zhou, Danelle F. James, Susan O’Brien - Blood 2015 cited by 656
- Low abundance of the matrix arm of complex I in mitochondria predicts longevity in mice
Authors: Satomi Miwa, Howsun Jow, Karen Baty, Amy J. Johnson, Rafal Czapiewski, Gabriele Saretzki, Achim Treumann, Thomas von Zglinicki - Nature Communications 2014 cited by 214
- The BTK Inhibitor ARQ 531 Targets Ibrutinib-Resistant CLL and Richter Transformation
Authors: Sean D. Reiff, Rose Mantel, Lisa L. Smith, J.T. Greene, Elizabeth M. Muhowski, Catherine A. Fabian, Virginia M. Goettl, Minh Tran, Bonnie K. Harrington, Kerry A. Rogers, Farrukh T. Awan, Kami J. Maddocks, Leslie A. Andritsos, Amy M. Lehman, Deepa Sampath, Rosa Lapalombella, Sudharshan Eathiraj, Giovanni Abbadessa, Brian Schwartz, Amy J. Johnson, John C. Byrd, Jennifer A. Woyach - Cancer Discovery 2018 cited by 170
- CAL-101, a p110δ selective phosphatidylinositol-3-kinase inhibitor for the treatment of B-cell malignancies, inhibits PI3K signaling and cellular viability
Authors: Brian J. Lannutti, Sarah Meadows, Sarah E. M. Herman, Adam Kashishian, Bart Steiner, Amy J. Johnson, John C. Byrd, Jeffrey Tyner, Marc Loriaux, Mike Deininger, Brian Druker, Kamal D. Puri, Roger G. Ulrich, Neill A. Giese - Blood 2010 cited by 718
- Cell-Cycle Reprogramming for PI3K Inhibition Overrides a Relapse-Specific C481S BTK Mutation Revealed by Longitudinal Functional Genomics in Mantle Cell Lymphoma
Authors: David Chiron, Maurizio Di Liberto, Peter Martin, Xiangao Huang, Jeff P. Sharman, Pedro Blecua, Susan Mathew, Priyanka Vijay, Ken Eng, Siraj M. Ali, Amy J. Johnson, Betty Chang, Scott Ely, Olivier Elemento, Christopher E. Mason, John P. Leonard, Selina Chen‐Kiang - Cancer Discovery 2014 cited by 272
- Bruton’s tyrosine kinase (BTK) function is important to the development and expansion of chronic lymphocytic leukemia (CLL)
Authors: Jennifer A. Woyach, Engin Bojnik, Amy S. Ruppert, Matthew Stefanovski, Virginia M. Goettl, Kelly A. Smucker, Lisa L. Smith, Jason A. Dubovsky, William H. Towns, Jessica MacMurray, Bonnie K. Harrington, Melanie E. Davis, Stefania Gobessi, Luca Laurenti, Betty Chang, Joseph J. Buggy, Dimitar G. Efremov, John C. Byrd, Amy J. Johnson - Blood 2013 cited by 219
- Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia
Authors: Rosa Lapalombella, Qingxiang Sun, Katie Williams, Larissa Tangeman, Shruti Jha, Yiming Zhong, Virginia M. Goettl, Emilia Mahoney, Caroline Berglund, Sneha Gupta, Alicia Farmer, Rajeswaran Mani, Amy J. Johnson, David Lucas, Xiaokui Mo, Dirk Daelemans, Vincent Sandanayaka, Sharon Shechter, Dilara McCauley, Sharon Shacham, Michael Kauffman, Yuh Min Chook, John C. Byrd - Blood 2012 cited by 297
- Single-agent ibrutinib in treatment-naïve and relapsed/refractory chronic lymphocytic leukemia: a 5-year experience
Authors: Susan O’Brien, Richard R. Furman, Steven Coutré, Ian W. Flinn, Jan A. Burger, Kristie A. Blum, Jeff P. Sharman, William G. Wierda, Jeffrey A. Jones, Weiqiang Zhao, Nyla A. Heerema, Amy J. Johnson, Ying Luan, Danelle F. James, Alvina D. Chu, John C. Byrd - Blood 2018 cited by 387
- Characterization of CLL exosomes reveals a distinct microRNA signature and enhanced secretion by activation of BCR signaling
Authors: Yuh-Ying Yeh, Hatice Gülçin Özer, Amy M. Lehman, Kami J. Maddocks, Lianbo Yu, Amy J. Johnson, John C. Byrd - Blood 2015 cited by 159
- Genetic heterogeneity of diffuse large B-cell lymphoma
Authors: Jenny Zhang, Vladimir Grubor, Cassandra Love, Anjishnu Banerjee, Kristy L. Richards, Piotr A. Mieczkowski, Cherie H. Dunphy, William Choi, Wing Y. Au, Gopesh Srivastava, Patricia Lugar, David A. Rizzieri, Anand S. Lagoo, Leon Bernal‐Mizrachi, Karen P. Mann, Christopher R. Flowers, Kikkeri N. Naresh, Andrew M. Evens, Leo I. Gordon, Magdalena Czader, Javed Gill, Eric D. Hsi, Qingquan Liu, Alice C. Fan, Katherine H. Walsh, Dereje D. Jima, Lisa L. Smith, Amy J. Johnson, John C. Byrd, Micah A. Luftig, Ting Ni, Jun Zhu, Amy Chadburn, Shawn Levy, David B. Dunson, Sandeep S. Davé - National Academy of Sciences, Proceedings of the National Academy of Sciences 2013 cited by 534
