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Amy S. Lee

Active 1981–2025

137
Papers
25,750
Citations
91
h-index
135
i10-index

Citations

Citations per year for Amy S. Lee1981: 1 citations1982: 2 citations1983: 6 citations1984: 9 citations1985: 12 citations1986: 21 citations1987: 41 citations1988: 51 citations1989: 54 citations1990: 32 citations1991: 67 citations1992: 85 citations1993: 67 citations1994: 62 citations1995: 66 citations1996: 52 citations1997: 100 citations1998: 89 citations1999: 138 citations2000: 94 citations2001: 95 citations2002: 109 citations2003: 102 citations2004: 136 citations2005: 215 citations2006: 192 citations2007: 266 citations2008: 253 citations2009: 301 citations2010: 303 citations2011: 272 citations2012: 376 citations2013: 279 citations2014: 356 citations2015: 233 citations2016: 183 citations2017: 244 citations2018: 159 citations2019: 745 citations2020: 759 citations2021: 735 citations2022: 556 citations2023: 427 citations2024: 569 citations2025: 265 citations2026: 4 citations

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 2,257 citing papers, 30.1% of this breakdownChina: 1,040 citing papers, 13.9% of this breakdownUnited Kingdom: 345 citing papers, 4.6% of this breakdownJapan: 309 citing papers, 4.1% of this breakdownGermany: 285 citing papers, 3.8% of this breakdownCanada: 278 citing papers, 3.7% of this breakdownItaly: 229 citing papers, 3% of this breakdownFrance: 207 citing papers, 2.8% of this breakdownSouth Korea: 191 citing papers, 2.5% of this breakdownIndia: 190 citing papers, 2.5% of this breakdownAustralia: 163 citing papers, 2.2% of this breakdownNetherlands: 126 citing papers, 1.7% of this breakdown
0%30.1%Other 25.1%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology57.2%
  • Medicine32.3%
  • Neuroscience2.3%
  • Immunology and Microbiology1.9%
  • Agricultural and Biological Sciences1.3%
  • Environmental Science1%
  • Other4%

Topics

  • Endoplasmic Reticulum Stress and Disease14.8%
  • Autophagy in Disease and Therapy6.9%
  • Heat shock proteins research3.5%
  • Pancreatic function and diabetes2.4%
  • RNA regulation and disease1.7%
  • Mitochondrial Function and Pathology1.1%
  • Other69.6%

Coauthors

All papers

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  1. ER chaperone GRP78/BiP translocates to the nucleus under stress and acts as a transcriptional regulator

    Authors: Ze Liu, Guanlin Liu, Dat P. Ha, Justin Wang, Min Xiong, Amy S. Lee - National Academy of Sciences, Proceedings of the National Academy of Sciences 2023 cited by 131

  2. Grp78 Loss in Epithelial Progenitors Reveals an Age-linked Role for Endoplasmic Reticulum Stress in Pulmonary Fibrosis

    Authors: Zea Borok, Masafumi Horie, Per Flodby, Hongjun Wang, Yixin Liu, Sivagini Ganesh, Amy L. Firth, Parviz Minoo, Changgong Li, Michael F. Beers, Amy S. Lee, Beiyun Zhou - American Journal of Respiratory and Critical Care Medicine 2019 cited by 179

  3. The ER chaperone and signaling regulator GRP78/BiP as a monitor of endoplasmic reticulum stress

    Authors: Amy S. Lee - Methods 2005 cited by 994

  4. Role of the Unfolded Protein Response Regulator GRP78/BiP in Development, Cancer, and Neurological Disorders

    Authors: Miao Wang, Shiuan Wey, Yi Zhang, Risheng Ye, Amy S. Lee - Antioxidants and Redox Signaling 2009 cited by 605

  5. Glucose-regulated proteins in cancer: molecular mechanisms and therapeutic potential

    Authors: Amy S. Lee - Nature reviews. Cancer 2014 cited by 638

  6. GRP78 Induction in Cancer: Therapeutic and Prognostic Implications

    Authors: Amy S. Lee - Cancer Research 2007 cited by 856

  7. The chaperone GRP78 is a host auxiliary factor for SARS-CoV-2 and GRP78 depleting antibody blocks viral entry and infection

    Authors: Anthony J. Carlos, Dat P. Ha, Da‐Wei Yeh, Richard Van Krieken, Chun-Chih Tseng, Pu Zhang, Parkash S. Gill, Keigo Machida, Amy S. Lee - Journal of Biological Chemistry 2021 cited by 174

  8. ER Stress Causes Rapid Loss of Intestinal Epithelial Stemness through Activation of the Unfolded Protein Response

    Authors: Jarom Heijmans, Jooske F. van Lidth de Jeude, Bon‐Kyoung Koo, Sanne L. Rosekrans, Mattheus C.B. Wielenga, Marc van de Wetering, Marc Ferrante, Amy S. Lee, J. J. M. Onderwater, James C. Paton, Adrienne W. Paton, A. Mieke Mommaas, Liudmila L. Kodach, James C.H. Hardwick, Daniël W. Hommes, Hans Clevers, Vanesa Muncan, Gijs R. van den Brink - Cell Reports 2013 cited by 294

  9. The Hydroxyquinoline Analogue YUM70 Inhibits GRP78 to Induce ER Stress–Mediated Apoptosis in Pancreatic Cancer

    Authors: Soma Samanta, Suhui Yang, Bikash Debnath, Ding Xue, Yuting Kuang, Kavya Ramkumar, Amy S. Lee, Mats Ljungman, Nouri Neamati - Cancer Research 2021 cited by 119

  10. Autophagy modulates lipid metabolism to maintain metabolic flexibility for Lkb1-deficient Kras-driven lung tumorigenesis

    Authors: Vrushank Bhatt, Khoosheh Khayati, Zhixian Hu, Amy S. Lee, Wali Kamran, Xiaoyang Su, Jessie Yanxiang Guo - Genes & Development 2019 cited by 116

  11. The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapies

    Authors: B Luo, Amy S. Lee - Oncogene 2012 cited by 565

  12. The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells

    Authors: Jiaxi Li, Min Ni, B Lee, E. Barrón, David R. Hinton, Amy S. Lee - Cell Death and Differentiation 2008 cited by 447

  13. Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targeting

    Authors: Min Ni, Yi Zhang, Amy S. Lee - Biochemical Journal 2011 cited by 534

  14. The critical role of GRP78 in physiologic and pathologic stress

    Authors: Kyle T. Pfaffenbach, Amy S. Lee - Current Opinion in Cell Biology 2010 cited by 337

  15. Cell Surface Relocalization of the Endoplasmic Reticulum Chaperone and Unfolded Protein Response Regulator GRP78/BiP

    Authors: Yi Zhang, Ren Liu, Min Ni, Parkash S. Gill, Amy S. Lee - Journal of Biological Chemistry 2010 cited by 328

  16. The stress-inducible ER chaperone GRP78/BiP is upregulated during SARS-CoV-2 infection and acts as a pro-viral protein

    Authors: Woo-Jin Shin, Dat P. Ha, Keigo Machida, Amy S. Lee - Nature Communications 2022 cited by 69

  17. ATF6 modulates SREBP2‐mediated lipogenesis

    Authors: Lingfang Zeng, Min Lü, Kazutoshi Mori, Shengzhan Luo, Amy S. Lee, Yi Zhu, John Y‐J Shyy - The EMBO Journal 2004 cited by 214

  18. Endoplasmic reticulum stress activates SRC, relocating chaperones to the cell surface where GRP78/CD109 blocks TGF-β signaling

    Authors: Yuan-Li Tsai, Dat P. Ha, He Zhao, Anthony J. Carlos, Shan Wei, Tsam Kiu Pun, Kaijin Wu, Ebrahim Zandi, Kevin R. Kelly, Amy S. Lee - National Academy of Sciences, Proceedings of the National Academy of Sciences 2018 cited by 141

  19. The glucose-regulated proteins: stress induction and clinical applications

    Authors: Amy S. Lee - Trends in Biochemical Sciences 2001 cited by 1,025

  20. The endothelial cell receptor GRP78 is required for mucormycosis pathogenesis in diabetic mice

    Authors: Mingfu Liu, Brad Spellberg, Quynh T. Phan, Yue Fu, Yong Fu, Amy S. Lee, John E. Edwards, Scott G. Filler, Ashraf S. Ibrahim - Journal of Clinical Investigation 2010 cited by 325

  21. Metformin Decreases Food Consumption and Induces Weight Loss in Subjects with Obesity with Type II Non‐Insulin‐Dependent Diabetes

    Authors: Amy S. Lee, John E. Morley - Obesity Research 1998 cited by 320

  22. The Unfolded Protein Response Regulator GRP78/BiP as a Novel Target for Increasing Chemosensitivity in Malignant Gliomas

    Authors: Peter Pyrko, Axel H. Schönthal, Florence M. Hofman, Thomas C. Chen, Amy S. Lee - Cancer Research 2007 cited by 448

  23. ATF6 as a Transcription Activator of the Endoplasmic Reticulum Stress Element: Thapsigargin Stress-Induced Changes and Synergistic Interactions with NF-Y and YY1

    Authors: Ming‐Qing Li, Peter Baumeister, Binayak Roy, Trevor Phan, Dolly M. Foti, Shengzhan Luo, Amy S. Lee - Molecular and Cellular Biology 2000 cited by 382

  24. Role of the unfolded protein response, GRP78 and GRP94 in organ homeostasis

    Authors: Genyuan Zhu, Amy S. Lee - Journal of Cellular Physiology 2014 cited by 306