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Arthur Christopoulos

Active 1997–2025

168
Papers
34,240
Citations
95
h-index
163
i10-index

Citations

Citations per year for Arthur Christopoulos1973: 1 citations1984: 1 citations1987: 3 citations1995: 1 citations1998: 2 citations1999: 3 citations2000: 2 citations2001: 5 citations2002: 24 citations2003: 40 citations2004: 66 citations2005: 100 citations2006: 127 citations2007: 184 citations2008: 207 citations2009: 234 citations2010: 316 citations2011: 377 citations2012: 283 citations2013: 351 citations2014: 478 citations2015: 405 citations2016: 463 citations2017: 523 citations2018: 584 citations2019: 1,653 citations2020: 1,657 citations2021: 1,532 citations2022: 1,134 citations2023: 768 citations2024: 1,096 citations2025: 533 citations2026: 21 citations1974–1983: no citations, so these years are not shown1985–1986: no citations, so these years are not shown1988–1994: no citations, so these years are not shown1996–1997: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 3,094 citing papers, 26.3% of this breakdownChina: 1,122 citing papers, 9.5% of this breakdownUnited Kingdom: 1,033 citing papers, 8.8% of this breakdownGermany: 726 citing papers, 6.2% of this breakdownAustralia: 590 citing papers, 5% of this breakdownItaly: 419 citing papers, 3.6% of this breakdownFrance: 405 citing papers, 3.4% of this breakdownCanada: 375 citing papers, 3.2% of this breakdownJapan: 329 citing papers, 2.8% of this breakdownSpain: 311 citing papers, 2.6% of this breakdownDenmark: 275 citing papers, 2.3% of this breakdownSwitzerland: 253 citing papers, 2.1% of this breakdown
0%26.3%Other 24.2%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology45%
  • Medicine28.6%
  • Neuroscience12.7%
  • Computer Science4%
  • Immunology and Microbiology1.8%
  • Psychology1.6%
  • Other6.3%

Topics

  • Receptor Mechanisms and Signaling13.6%
  • Neuropeptides and Animal Physiology7%
  • Computational Drug Discovery Methods3.6%
  • Neuroscience and Neuropharmacology Research3.2%
  • Monoclonal and Polyclonal Antibodies Research2.1%
  • Neurotransmitter Receptor Influence on Behavior2%
  • Other68.5%

Coauthors

All papers

Open in search
  1. The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors

    Authors: S P H Alexander, Arthur Christopoulos, Anthony P. Davenport, Eamonn Kelly, Alistair Mathie, John A. Peters, Emma L. Veale, Jane F Armstrong, Elena Faccenda, Simon D Harding, Jamie A. Davies, Maria P. Abbracchio, George Abraham, Alexander I. Agoulnik, Wayne Alexander, Khaled Alhosaini, Magnus Bäck, Jillian G. Baker, Nicholas M. Barnes, Ross A. D. Bathgate, Jean‐Martin Beaulieu, Annette G. Beck‐Sickinger, Maik Behrens, Kenneth E. Bernstein, Bernhard Bettler, N.J.M. Birdsall, Victoria A. Blaho, François Boulay, Corinne Bousquet, Hans Bräuner‐Osborne, Geoffrey Burnstock, Girolamo Calò, Justo P. Castaño, Kevin Catt, Stefania Ceruti, Paul L. Chazot, Nan Chiang, Bice Chini, Jerold Chun, Antonia Cianciulli, Olivier Civelli, Lucie H. Clapp, Réjean Couture, Helen M. Cox, Zsolt Csaba, Cláes Dahlgren, Gordon Dent, Steven D. Douglas, Pascal Dournaud, Satoru Eguchi, Emanuel Escher, Edward J. Filardo, Tung M. Fong, Marta Fumagalli, Raul R. Gainetdinov, Michael L. Garelja, Marc de Gasparo, Craig Gerard, Marvin C. Gershengorn, Fernand Gobeil, Theodore L. Goodfriend, Cyril Goudet, Lukas Grätz, Karen J. Gregory, Andrew L. Gundlach, Jörg Hamann, Julien Hanson, Richard L. Hauger, Debbie L. Hay, Ákos Heinemann, Deron R. Herr, Morley D. Hollenberg, Nicholas D. Holliday, Mastgugu Horiuchi, Daniël Hoyer, László Hunyady, Ahsan Husain, Adriaan P. IJzerman, Tadashi Inagami, Kenneth A. Jacobson, Robert T. Jensen, Ralf Jockers, Deepa Jonnalagadda, Sadashiva S. Karnik, Klemens Kaupmann, Jacqueline Kemp, Charles Kennedy, Yasuyuki Kihara, Takio Kitazawa, Paweł Kozielewicz, Hans‐Jürgen Kreienkamp, Jyrki P. Kukkonen, Tobias Langenhan, Dan Larhammar, Katie Leach, Davide Lecca, John D. Lee, Susan E. Leeman, Jérôme Leprince, Xaria X. Li and 66 more - British Journal of Pharmacology 2023 cited by 388

  2. Mechanisms of signalling and biased agonism in G protein-coupled receptors

    Authors: Denise Wootten, Arthur Christopoulos, Maria Martí-Solano, M. Madan Babu, Patrick M. Sexton - Nature Reviews Molecular Cell Biology 2018 cited by 737

  3. Activation and allosteric modulation of a muscarinic acetylcholine receptor

    Authors: Andrew C. Kruse, Aaron M. Ring, Aashish Manglik, Jianxin Hu, Kelly Hu, Katrin Eitel, Harald Hübner, Els Pardon, Céline Valant, Patrick M. Sexton, Arthur Christopoulos, Christian C. Felder, Peter Gmeiner, Jan Steyaert, William I. Weis, K. Christopher García, Jürgen Wess, Brian K. Kobilka - Nature 2013 cited by 920

  4. Signalling bias in new drug discovery: detection, quantification and therapeutic impact

    Authors: Terry Kenakin, Arthur Christopoulos - Nature Reviews Drug Discovery 2012 cited by 725

  5. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein‐coupled receptors

    Authors: S P H Alexander, Arthur Christopoulos, Anthony P. Davenport, Eamonn Kelly, Alistair Mathie, John A. Peters, Emma L. Veale, Jane F Armstrong, Elena Faccenda, Simon D Harding, Adam J Pawson, Christopher Southan, Jamie A. Davies, Maria P. Abbracchio, Wayne Alexander, Khaled Alhosaini, Magnus Bäck, Nicholas M. Barnes, Ross A. D. Bathgate, Jean‐Martin Beaulieu, Kenneth E. Bernstein, Bernhard Bettler, N.J.M. Birdsall, Victoria A. Blaho, François Boulay, Corinne Bousquet, Hans Bräuner‐Osborne, Geoffrey Burnstock, Girolamo Calò, Justo P. Castaño, Kevin Catt, Stefania Ceruti, Paul L. Chazot, Nan Chiang, Bice Chini, Jerold Chun, Antonia Cianciulli, Olivier Civelli, Lucie H. Clapp, Réjean Couture, Zsolt Csaba, Cláes Dahlgren, Gordon Dent, Khuraijam Dhanachandra Singh, Steven D. Douglas, Pascal Dournaud, Satoru Eguchi, Emanuel Escher, Edward J. Filardo, Tung M. Fong, Marta Fumagalli, Raul R. Gainetdinov, Marc de Gasparo, Craig Gerard, Marvin C. Gershengorn, Fernand Gobeil, Theodore L. Goodfriend, Cyril Goudet, Karen J. Gregory, Andrew L. Gundlach, Jörg Hamann, Julien Hanson, Richard L. Hauger, Debbie L. Hay, Ákos Heinemann, Morley D. Hollenberg, Nicholas D. Holliday, Mastgugu Horiuchi, Daniël Hoyer, László Hunyady, Ahsan Husain, Adriaan P. IJzerman, Tadashi Inagami, Kenneth A. Jacobson, Robert T. Jensen, Ralf Jockers, Deepa Jonnalagadda, Sadashiva S. Karnik, Klemens Kaupmann, Jacqueline Kemp, Charles Kennedy, Yasuyuki Kihara, Takio Kitazawa, Paweł Kozielewicz, Hans‐Jürgen Kreienkamp, Jyrki P. Kukkonen, Tobias Langenhan, Katie Leach, Davide Lecca, John D. Lee, Susan E. Leeman, Jérôme Leprince, Xaria X. Li, Tom A. Williams, Stephen J. Lolait, Amelie Lupp, Robyn Macrae, Janet J. Maguire, Jean Mazella, Craig A. McArdle and 55 more - British Journal of Pharmacology 2021 cited by 488

  6. Emerging paradigms in GPCR allostery: implications for drug discovery

    Authors: Denise Wootten, Arthur Christopoulos, Patrick M. Sexton - Nature Reviews Drug Discovery 2013 cited by 493

  7. Structural insights into G-protein-coupled receptor allostery

    Authors: David M. Thal, Alisa Glukhova, Patrick M. Sexton, Arthur Christopoulos - Nature 2018 cited by 339

  8. Positive allosteric mechanisms of adenosine A1 receptor-mediated analgesia

    Authors: Christopher J. Draper-Joyce, Rebecca F. Bhola, Jinan Wang, Apurba Bhattarai, Thi Nguyen, India Cowie-Kent, Kelly O’Sullivan, Ling Yeong Chia, Hariprasad Venugopal, Céline Valant, David M. Thal, Denise Wootten, Nicolas Panel, Jens Carlsson, MacDonald J. Christie, Paul J. White, Peter J. Scammells, Lauren T. May, Patrick M. Sexton, Radostin Danev, Yinglong Miao, Alisa Glukhova, Wendy L. Imlach, Arthur Christopoulos - Nature 2021 cited by 158

  9. The role of kinetic context in apparent biased agonism at GPCRs

    Authors: Carmen Klein Herenbrink, David A. Sykes, Prashant Donthamsetti, Meritxell Canals, Thomas Coudrat, Jeremy Shonberg, Peter J. Scammells, Ben Capuano, Patrick M. Sexton, Steven J. Charlton, Jonathan A. Javitch, Arthur Christopoulos, J. Robert Lane - Nature Communications 2016 cited by 337

  10. Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders

    Authors: P. Jeffrey Conn, Arthur Christopoulos, Craig W. Lindsley - Nature Reviews Drug Discovery 2008 cited by 1,042

  11. Muscarinic acetylcholine receptors: novel opportunities for drug development

    Authors: Andrew C. Kruse, Brian K. Kobilka, Dinesh Gautam, Patrick M. Sexton, Arthur Christopoulos, Jürgen Wess - Nature Reviews Drug Discovery 2014 cited by 439

  12. Allosteric Modulation as a Unifying Mechanism for Receptor Function and Regulation

    Authors: Jean‐Pierre Changeux, Arthur Christopoulos - Cell 2016 cited by 350

  13. THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: G protein‐coupled receptors

    Authors: S P H Alexander, Arthur Christopoulos, Anthony P. Davenport, Eamonn Kelly, Alistair Mathie, John A. Peters, Emma L. Veale, Jane F Armstrong, Elena Faccenda, Simon D Harding, Adam J Pawson, Joanna L Sharman, Christopher Southan, Jamie A. Davies, CGTP Collaborators - British Journal of Pharmacology 2019 cited by 712

  14. Activation of the GLP-1 receptor by a non-peptidic agonist

    Authors: Peishen Zhao, Yi-Lynn Liang, Matthew J. Belousoff, Giuseppe Deganutti, Madeleine M. Fletcher, Francis S. Willard, Michael G. Bell, Michael E. Christe, Kyle W. Sloop, Asuka Inoue, Tin T. Truong, Lachlan Clydesdale, Sebastian G. B. Furness, Arthur Christopoulos, Ming-Wei Wang, Laurence J. Miller, Christopher A. Reynolds, Radostin Danev, Patrick M. Sexton, Denise Wootten - Nature 2020 cited by 168

  15. Dominant Negative G Proteins Enhance Formation and Purification of Agonist-GPCR-G Protein Complexes for Structure Determination

    Authors: Yi-Lynn Liang, Peishen Zhao, Christopher J. Draper-Joyce, Jo‐Anne Baltos, Alisa Glukhova, Tin T. Truong, Lauren T. May, Arthur Christopoulos, Denise Wootten, Patrick M. Sexton, Sebastian G. B. Furness - ACS Pharmacology & Translational Science 2018 cited by 156

  16. Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor–Gs complex

    Authors: Yi-Lynn Liang, Maryam Khoshouei, Alisa Glukhova, Sebastian G. B. Furness, Peishen Zhao, Lachlan Clydesdale, Cassandra Koole, Tin T. Truong, David M. Thal, Saifei Lei, Mazdak Radjainia, Radostin Danev, Wolfgang Baumeister, Ming-Wei Wang, Laurence J. Miller, Arthur Christopoulos, Patrick M. Sexton, Denise Wootten - Nature 2018 cited by 332

  17. Functional Selectivity and Classical Concepts of Quantitative Pharmacology

    Authors: Jonathan D. Urban, William P. Clarke, Mark von Zastrow, David E. Nichols, Brian K. Kobilka, Harel Weinstein, Jonathan A. Javitch, Bryan L. Roth, Arthur Christopoulos, Patrick M. Sexton, Keith J. Miller, Michael Spedding, Richard B. Mailman - Journal of Pharmacology and Experimental Therapeutics 2006 cited by 1,109

  18. A Simple Method for Quantifying Functional Selectivity and Agonist Bias

    Authors: Terry Kenakin, Christian Watson, Vanessa Muniz‐Medina, Arthur Christopoulos, Steven Novick - ACS Chemical Neuroscience 2011 cited by 486

  19. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Introduction and Other Protein Targets

    Authors: S P H Alexander, Eamonn Kelly, Alistair Mathie, John A. Peters, Emma L. Veale, Jane F Armstrong, Elena Faccenda, Simon D Harding, Adam J Pawson, Christopher Southan, O. Buneman, John A. Cidlowski, Arthur Christopoulos, Anthony P. Davenport, Doriano Fabbro, Michael Spedding, Jörg Striessnig, Jamie A. Davies, Katelin E. Ahlers‐Dannen, Mohammed Alqinyah, Thiruma V. Arumugam, Christopher Bodle, Josephine Buo Dagner, Bandana Chakravarti, Shreoshi Pal Choudhuri, Kirk M. Druey, Rory A. Fisher, Kyle J. Gerber, John R. Hepler, Shelley B. Hooks, Havish S. Kantheti, Behirda Karaj, Somayeh Layeghi‐Ghalehsoukhteh, Jae‐Kyung Lee, Zili Luo, Kirill A. Martemyanov, Luke D. Mascarenhas, Harrison J. McNabb, Carolina Montañez‐Miranda, Osita W. Ogujiofor, H. T. Phan, David L. Roman, Vincent Shaw, Benita Sjögren, Christopher G. Sobey, Mackenzie M. Spicer, Katherine E. Squires, Laurie P. Sutton, Menbere Wendimu, Thomas M. Wilkie, Keqiang Xie, Qian Zhang, Yalda Zolghadri - British Journal of Pharmacology 2021 cited by 275

  20. Phase-plate cryo-EM structure of a class B GPCR–G-protein complex

    Authors: Yi-Lynn Liang, Maryam Khoshouei, Mazdak Radjainia, Yan Zhang, Alisa Glukhova, Jeffrey Tarrasch, David M. Thal, Sebastian G. B. Furness, George Christopoulos, Thomas Coudrat, Radostin Danev, Wolfgang Baumeister, Laurence J. Miller, Arthur Christopoulos, Brian K. Kobilka, Denise Wootten, Georgios Skiniotis, Patrick M. Sexton - Nature 2017 cited by 480

  21. Polar transmembrane interactions drive formation of ligand-specific and signal pathway-biased family B G protein-coupled receptor conformations

    Authors: Denise Wootten, John Simms, Laurence J. Miller, Arthur Christopoulos, Patrick M. Sexton - National Academy of Sciences, Proceedings of the National Academy of Sciences 2013 cited by 254

  22. Fitting Models to Biological Data Using Linear and Nonlinear Regression

    Authors: Harvey Motulsky, Arthur Christopoulos - 2004 cited by 1,371

  23. International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification. XXXVIII. Update on Terms and Symbols in Quantitative Pharmacology

    Authors: Richard R. Neubig, Michael Spedding, Terry Kenakin, Arthur Christopoulos - Pharmacological Reviews 2003 cited by 660

  24. Structural basis for modulation of a G-protein-coupled receptor by allosteric drugs

    Authors: Ron O. Dror, Hillary F. Green, Céline Valant, David W. Borhani, James R. Valcourt, Albert C. Pan, Daniel H. Arlow, Meritxell Canals, J. Robert Lane, Raphaël Rahmani, Jonathan B. Baell, Patrick M. Sexton, Arthur Christopoulos, David E. Shaw - Nature 2013 cited by 425