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Brian L. West

Active 1983–2024

78
Papers
26,924
Citations
70
h-index
76
i10-index

Citations

Citations per year for Brian L. West1961: 1 citations1984: 4 citations1985: 12 citations1986: 23 citations1987: 39 citations1988: 58 citations1989: 53 citations1990: 56 citations1991: 61 citations1992: 45 citations1993: 49 citations1994: 36 citations1995: 39 citations1996: 42 citations1997: 61 citations1998: 87 citations1999: 87 citations2000: 102 citations2001: 92 citations2002: 79 citations2003: 81 citations2004: 51 citations2005: 55 citations2006: 49 citations2007: 76 citations2008: 65 citations2009: 71 citations2010: 120 citations2011: 163 citations2012: 221 citations2013: 284 citations2014: 254 citations2015: 340 citations2016: 435 citations2017: 521 citations2018: 602 citations2019: 1,192 citations2020: 1,470 citations2021: 1,577 citations2022: 1,129 citations2023: 853 citations2024: 1,180 citations2025: 618 citations2026: 25 citations1962–1983: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 4,439 citing papers, 34.2% of this breakdownChina: 1,476 citing papers, 11.4% of this breakdownGermany: 733 citing papers, 5.6% of this breakdownUnited Kingdom: 720 citing papers, 5.5% of this breakdownFrance: 537 citing papers, 4.1% of this breakdownItaly: 490 citing papers, 3.8% of this breakdownCanada: 387 citing papers, 3% of this breakdownJapan: 373 citing papers, 2.9% of this breakdownAustralia: 372 citing papers, 2.9% of this breakdownNetherlands: 318 citing papers, 2.5% of this breakdownSwitzerland: 316 citing papers, 2.4% of this breakdownSpain: 289 citing papers, 2.2% of this breakdown
0%34.2%Other 19.5%

Institutions

Fields

  • Medicine31.4%
  • Biochemistry, Genetics and Molecular Biology28.7%
  • Neuroscience20.8%
  • Immunology and Microbiology14.7%
  • Computer Science1.6%
  • Engineering0.7%
  • Other2.1%

Topics

  • Neuroinflammation and Neurodegeneration Mechanisms7.9%
  • Immune cells in cancer7.9%
  • Cancer Immunotherapy and Biomarkers3.9%
  • Melanoma and MAPK Pathways2.8%
  • Immunotherapy and Immune Responses2%
  • Immune Cell Function and Interaction1.9%
  • Other73.6%

Coauthors

All papers

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  1. Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain

    Authors: Monica R. P. Elmore, Allison R. Najafi, Maya A. Koike, Nabil N. Dagher, Elizabeth E. Spangenberg, Rachel Rice, Masashi Kitazawa, Bernice Matusow, Hoa Nguyen, Brian L. West, Kim N. Green - Neuron 2014 cited by 2,030

  2. Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer’s disease model

    Authors: Elizabeth E. Spangenberg, Paul Severson, Lindsay A. Hohsfield, Joshua Crapser, Jiazhong Zhang, Elizabeth A. Burton, Ying Zhang, Wayne Spevak, Jack T. Lin, Nicole Phan, Gaston Habets, Andrey Rymar, Garson Tsang, Jason Walters, Marika Nespi, Parmveer Singh, S Broome, Prabha N. Ibrahim, Chao Zhang, Gideon Bollag, Brian L. West, Kim N. Green - Nature Communications 2019 cited by 998

  3. CSF1/CSF1R Blockade Reprograms Tumor-Infiltrating Macrophages and Improves Response to T-cell Checkpoint Immunotherapy in Pancreatic Cancer Models

    Authors: Yu Zhu, Brett L. Knolhoff, Melissa A. Meyer, Timothy M. Nywening, Brian L. West, Jingqin Luo, Andrea Wang‐Gillam, S. Peter Goedegebuure, David C. Linehan, David G. DeNardo - Cancer Research 2014 cited by 1,287

  4. Orally administered colony stimulating factor 1 receptor inhibitor PLX3397 in recurrent glioblastoma: an Ivy Foundation Early Phase Clinical Trials Consortium phase II study

    Authors: Nicholas Butowski, Howard Colman, John de Groot, Antonio Omuro, Lakshmi Nayak, Patrick Y. Wen, Timothy F. Cloughesy, Adhirai Marimuthu, Sam Haidar, Arie Perry, Jason T. Huse, Joanna J. Phillips, Brian L. West, K. B. Nolop, Henry H. Hsu, Keith L. Ligon, Annette M. Molinaro, Michael D. Prados - Neuro-Oncology 2015 cited by 580

  5. Eliminating microglia in Alzheimer’s mice prevents neuronal loss without modulating amyloid-β pathology

    Authors: Elizabeth E. Spangenberg, Rafael J. Lee, Allison R. Najafi, Rachel Rice, Monica R. P. Elmore, Mathew Blurton‐Jones, Brian L. West, Kim N. Green - Brain 2016 cited by 737

  6. Leukocyte Complexity Predicts Breast Cancer Survival and Functionally Regulates Response to Chemotherapy

    Authors: David G. DeNardo, Donal J. Brennan, Elton Rexhepaj, Brian Ruffell, Stephen L. Shiao, Stephen F. Madden, William M. Gallagher, Nikhil Wadhwani, Scott D. Keil, Sharfaa A. Junaid, Hope S. Rugo, E. Shelley Hwang, Karin Jirström, Brian L. West, Lisa M. Coussens - Cancer Discovery 2011 cited by 1,718

  7. Targeting Tumor-Infiltrating Macrophages Decreases Tumor-Initiating Cells, Relieves Immunosuppression, and Improves Chemotherapeutic Responses

    Authors: Jonathan B. Mitchem, Donal J. Brennan, Brett L. Knolhoff, Brian A. Belt, Yu Zhu, Dominic E. Sanford, Larisa Belaygorod, Danielle Carpenter, Lynne Collins, David Piwnica‐Worms, Stephen M. Hewitt, Girish Mallya Udupi, William M. Gallagher, Craig D. Wegner, Brian L. West, Andrea Wang‐Gillam, Peter S. Goedegebuure, David C. Linehan, David G. DeNardo - Cancer Research 2012 cited by 941

  8. Microglia protect against brain injury and their selective elimination dysregulates neuronal network activity after stroke

    Authors: Gergely Szalay, Bernadett Martinecz, Nikolett Lénárt, Zsuzsanna Környei, Barbara Orsolits, Linda Judák, Eszter Császár, Rebeka Fekete, Brian L. West, Gergely Katona, Balázs Rózsa, Ádám Dénes - Nature Communications 2016 cited by 587

  9. Microglia modulate blood flow, neurovascular coupling, and hypoperfusion via purinergic actions

    Authors: Eszter Császár, Nikolett Lénárt, Csaba Cserép, Zsuzsanna Környei, Rebeka Fekete, Balázs Pósfai, Diána Balázsfi, Balázs Hangya, Anett D. Schwarcz, Eszter Szabadits, Dávid Szöllősi, Krisztián Szigeti, Domokos Máthé, Brian L. West, Katalin Sviatkó, Ana Rita Brás, Jean-Charles Mariani, Andrea Kliewer, Zsolt Lenkei, László Hricisák, Zoltán Benyó, Mária Baranyi, Beáta Sperlágh, Ákos Menyhárt, Eszter Farkas, Ádám Dénes - The Journal of Experimental Medicine 2022 cited by 268

  10. Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma

    Authors: Gideon Bollag, Peter Hirth, James Tsai, Jiazhong Zhang, Prabha N. Ibrahim, Hanna Cho, Wayne Spevak, Chao Zhang, Ying Zhang, Gaston Habets, Elizabeth A. Burton, Bernice H. Wong, Garson Tsang, Brian L. West, Ben Powell, Rafe Shellooe, Adhirai Marimuthu, Hoa Nguyen, Kam Y. J. Zhang, Dean R. Artis, Joseph Schlessinger, Fei Su, Brian Higgins, Raman Iyer, Kurt D’Andrea, Astrid Koehler, Michael Stumm, Paul Lin, Richard J. Lee, Joseph F. Grippo, Igor Puzanov, Kevin B. Kim, Antoni Ribas, Grant A. McArthur, Jeffrey A. Sosman, Paul B. Chapman, Keith T. Flaherty, Xiaowei Xu, Katherine L. Nathanson, K. B. Nolop - Nature 2010 cited by 1,837

  11. Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor

    Authors: William D. Tap, Zev A. Wainberg, Stephen P. Anthony, Prabha N. Ibrahim, Chao Zhang, John H. Healey, Bartosz Chmielowski, Arthur P. Staddon, Allen Lee Cohn, Geoffrey I. Shapiro, Vicki L. Keedy, Arun S. Singh, Igor Puzanov, Eunice L. Kwak, Andrew J. Wagner, Daniel D. Von Hoff, Glen J. Weiss, Ramesh K. Ramanathan, Jiazhong Zhang, Gaston Habets, Ying Zhang, Elizabeth A. Burton, Gary C. Visor, Laura Sanftner, Paul Severson, Hoa Nguyen, Marie J. Kim, Adhirai Marimuthu, Garson Tsang, Rafe Shellooe, C. M. Gee, Brian L. West, Peter Hirth, K. B. Nolop, Matt van de Rijn, Henry H. Hsu, Charles Peterfy, Paul Lin, Sandra Tong-Starksen, Gideon Bollag - New England Journal of Medicine 2015 cited by 582

  12. CSF1R Signaling Blockade Stanches Tumor-Infiltrating Myeloid Cells and Improves the Efficacy of Radiotherapy in Prostate Cancer

    Authors: Jingying Xu, Jemima Escamilla, Stephen Mok, John David, Saul J. Priceman, Brian L. West, Gideon Bollag, William H. McBride, Lily Wu - Cancer Research 2013 cited by 561

  13. Colony-stimulating factor 1 receptor inhibition prevents microglial plaque association and improves cognition in 3xTg-AD mice

    Authors: Nabil N. Dagher, Allison R. Najafi, Kara M. Neely Kayala, Monica R. P. Elmore, Terra E. White, Rodrigo Medeiros, Brian L. West, Kim N. Green - Journal of Neuroinflammation 2015 cited by 525

  14. Replacement of microglia in the aged brain reverses cognitive, synaptic, and neuronal deficits in mice

    Authors: Monica R. P. Elmore, Lindsay A. Hohsfield, Enikö A. Kramár, Lilach Soreq, Rafael J. Lee, Stephanie T. Pham, Allison R. Najafi, Elizabeth E. Spangenberg, Marcelo A. Wood, Brian L. West, Kim N. Green - Aging Cell 2018 cited by 394

  15. Microglial Stimulation of Glioblastoma Invasion Involves Epidermal Growth Factor Receptor (EGFR) and Colony Stimulating Factor 1 Receptor (CSF-1R) Signaling

    Authors: Salvatore J. Coniglio, Eliseo Eugenin, Kostantin Dobrenis, E. Richard Stanley, Brian L. West, Marc Symons, Jeffrey E. Segall - Molecular Medicine 2012 cited by 443

  16. Activated microglia drive demyelination via CSF1R signaling

    Authors: Dave E. Marzan, Valérie Brügger‐Verdon, Brian L. West, Shane A. Liddelow, Jayshree Samanta, James L. Salzer - Glia 2021 cited by 152

  17. Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

    Authors: James Tsai, John Tayu Lee, Weiru Wang, Jiazhong Zhang, Hanna Cho, Shumeye Mamo, Ryan Bremer, S. Gillette, Jun Kong, Nikolas K. Haass, Katrin Sproesser, Ling Li, Keiran S.M. Smalley, Daniel W. Fong, Yongliang Zhu, Adhirai Marimuthu, Hoa Nguyen, Billy Lam, Jennifer Liu, Ivana Cheung, Julie Rice, Yoshihisa Suzuki, Catherine A. Luu, Calvin Settachatgul, Rafe Shellooe, John Cantwell, Sung‐Hou Kim, Joseph Schlessinger, Kam Y. J. Zhang, Brian L. West, Ben Powell, Gaston Habets, Chao Zhang, Prabha N. Ibrahim, Peter Hirth, Dean R. Artis, Meenhard Herlyn, Gideon Bollag - National Academy of Sciences, Proceedings of the National Academy of Sciences 2008 cited by 1,346

  18. Mutation of NLRC4 causes a syndrome of enterocolitis and autoinflammation

    Authors: Neil Romberg, Khatoun Al Moussawi, Carol Nelson‐Williams, Amy L. Stiegler, Erin Loring, Murim Choi, John D. Overton, Eric Meffre, Mustafa K. Khokha, Anita Hüttner, Brian L. West, Nikolai A. Podoltsev, Titus J. Boggon, Barbara I. Kazmierczak, Richard P. Lifton - Nature Genetics 2014 cited by 510

  19. Phase Ib study of the combination of pexidartinib (PLX3397), a CSF-1R inhibitor, and paclitaxel in patients with advanced solid tumors

    Authors: Robert Wesolowski, Neelesh Sharma, Laura Reebel, Mary Beth Rodal, Peck Alexandra, Brian L. West, Adhirai Marimuthu, Paul Severson, David A. Karlin, Afshin Dowlati, Mai H. Le, Lisa M. Coussens, Hope S. Rugo - Therapeutic Advances in Medical Oncology 2019 cited by 169

  20. Inhibition of CSF-1 Receptor Improves the Antitumor Efficacy of Adoptive Cell Transfer Immunotherapy

    Authors: Stephen Mok, Richard C. Koya, Christopher Tsui, Jingying Xu, Lídia Robert, Lily Wu, Thomas G. Graeber, Brian L. West, Gideon Bollag, Antoni Ribas - Cancer Research 2013 cited by 318

  21. Microglial repopulation resolves inflammation and promotes brain recovery after injury

    Authors: Rachel Rice, Jason T. Pham, Rafael J. Lee, Allison R. Najafi, Brian L. West, Kim N. Green - Glia 2017 cited by 230

  22. Inhibition of colony stimulating factor-1 receptor abrogates microenvironment-mediated therapeutic resistance in gliomas

    Authors: Dongyao Yan, Joanna Kowal, Leila Akkari, Alberto J. Schuhmacher, J. T. Huse, Brian L. West, Johanna A. Joyce - Oncogene 2017 cited by 248

  23. Elimination of microglia improves cognitive function following cranial irradiation

    Authors: Munjal M. Acharya, Kim N. Green, Barrett D. Allen, Allison R. Najafi, Amber R. Syage, Harutyun Minasyan, Mi T. Le, Takumi Kawashita, Erich Giedzinski, Vipan K. Parihar, Brian L. West, Janet E. Baulch, Charles L. Limoli - Scientific Reports 2016 cited by 270

  24. Small-molecule MAPK inhibitors restore radioiodine incorporation in mouse thyroid cancers with conditional BRAF activation

    Authors: Debyani Chakravarty, Elmer Santos, Mabel Ryder, Jeffrey A. Knauf, Xiao-Hui Liao, Brian L. West, Gideon Bollag, Richard Kolesnick, Tin Htwe Thin, Neal Rosen, Pat Zanzonico, Steven M. Larson, Samuel Refetoff, Ronald Ghossein, James A. Fagin - Journal of Clinical Investigation 2011 cited by 387