Bryan T. Hennessy
Active 2004–2025
- 101
- Papers
- 29,021
- Citations
- 71
- h-index
- 100
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology47.5%
- Medicine44.8%
- Immunology and Microbiology1.8%
- Computer Science1.6%
- Neuroscience0.8%
- Engineering0.7%
- Other2.8%
Topics
- Breast Cancer Treatment Studies5.1%
- PI3K/AKT/mTOR signaling in cancer3.9%
- HER2/EGFR in Cancer Research3.6%
- PARP inhibition in cancer therapy3.2%
- Cancer Cells and Metastasis3.1%
- Cancer Genomics and Diagnostics3%
- Other78.1%
Coauthors
- Gordon B. Mills40
- Ana M. González-Angulo19
- Sinéad Toomey19
- Mark Carey17
- Gabriel N. Hortobágyi13
- Patrick G. Morris12
- Vicente Valero11
- Yiling Lu11
- Katherine Stemke‐Hale10
- Liam Grogan10
- Oscar S. Breathnach10
- John Crown9
- Mattia Cremona9
- Stephen F. Madden9
- Funda Meric‐Bernstam7
- Zhenlin Ju7
- Alex J. Eustace6
- Angela M. Farrelly6
- Ayşegül A. Şahin6
- Aňa Lluch6
- Elaine W. Kay6
- Jie Li6
- Kirsten M. Timms6
- Roshan Agarwal6
All papers
- Response to Neoadjuvant Therapy and Long-Term Survival in Patients With Triple-Negative Breast Cancer
Authors: Cornelia Liedtke, Chafika Mazouni, Kenneth R. Hess, Fabrice André, Attila Tordai, Jaime Mejia, W. Fraser Symmans, Ana M. González-Angulo, Bryan T. Hennessy, Marjorie Green, Massimo Cristofanilli, Gabriel N. Hortobágyi, Lajos Pusztai - Journal of Clinical Oncology 2008 cited by 2,906
- Homologous Recombination Deficiency (HRD) Score Predicts Response to Platinum-Containing Neoadjuvant Chemotherapy in Patients with Triple-Negative Breast Cancer
Authors: Melinda L. Telli, Kirsten M. Timms, Julia Reid, Bryan T. Hennessy, Gordon B. Mills, Kristin C. Jensen, Zoltán Szállási, William T. Barry, Eric P. Winer, Nadine Tung, Steven J. Isakoff, Paula D. Ryan, April Greene-Colozzi, Alexander Gutin, Zaina Sangale, Diana Iliev, Chris Neff, Victor Abkevich, Joshua T. Jones, Jerry S. Lanchbury, Anne‐Renee Hartman, Judy E. Garber, James M. Ford, Daniel P. Silver, Andrea L. Richardson - Clinical Cancer Research 2016 cited by 1,163
- Measurement of Residual Breast Cancer Burden to Predict Survival After Neoadjuvant Chemotherapy
Authors: W. Fraser Symmans, Florentia Peintinger, Christos Hatzis, Radhika Rajan, Henry M. Kuerer, Vicente Valero, Lina Assad, Anna W. Poniecka, Bryan T. Hennessy, Marjorie Green, Aman U. Buzdar, S. Eva Singletary, Gabriel N. Hortobágyi, Lajos Pusztai - Journal of Clinical Oncology 2007 cited by 1,662
- Exploiting the PI3K/AKT Pathway for Cancer Drug Discovery
Authors: Bryan T. Hennessy, Debra L. Smith, Prahlad T. Ram, Yiling Lu, Gordon B. Mills - Nature Reviews Drug Discovery 2005 cited by 2,163
- Patterns of genomic loss of heterozygosity predict homologous recombination repair defects in epithelial ovarian cancer
Authors: Victor Abkevich, Kirsten M. Timms, Bryan T. Hennessy, Jennifer Potter, Mark Carey, Lisa Meyer, Karen Smith‐McCune, Russell Broaddus, K.H. Lu, J Chen, Thuan Van Tran, Deniece R. Williams, Diana Iliev, Srikanth Jammulapati, Liesel M. FitzGerald, Thomas C. Krivak, Julie A. DeLoia, Alexander Gutin, Gordon B. Mills, J. S. Lanchbury - British Journal of Cancer 2012 cited by 852
- An Integrative Genomic and Proteomic Analysis of PIK3CA, PTEN, and AKT Mutations in Breast Cancer
Authors: Katherine Stemke‐Hale, Ana M. González-Angulo, Aňa Lluch, Richard M. Neve, Wen-Lin Kuo, Michael A. Davies, Mark Carey, Zhi Hu, Yinghui Guan, Ayşegül A. Şahin, W. Fraser Symmans, Lajos Pusztai, Laura K. Nolden, Hugo M. Horlings, Katrien Berns, Mien‐Chie Hung, Marc J. van de Vijver, Vicente Valero, Joe W. Gray, René Bernards, Gordon B. Mills, Bryan T. Hennessy - Cancer Research 2008 cited by 1,043
- A Functional Genetic Approach Identifies the PI3K Pathway as a Major Determinant of Trastuzumab Resistance in Breast Cancer
Authors: Katrien Berns, Hugo M. Horlings, Bryan T. Hennessy, Mandy Madiredjo, E. Marielle Hijmans, Karin Beelen, Sabine C. Linn, Ana M. González-Angulo, Katherine Stemke‐Hale, Michael Hauptmann, Roderick L. Beijersbergen, Gordon B. Mills, Marc J. van de Vijver, René Bernards - Cancer Cell 2007 cited by 1,623
- Ponesimod Compared With Teriflunomide in Patients With Relapsing Multiple Sclerosis in the Active-Comparator Phase 3 OPTIMUM Study
Authors: Ludwig Kappos, Robert J. Fox, Michel Burcklen, Mark S. Freedman, Eva Havrdová, Bryan T. Hennessy, Reinhard Hohlfeld, Fred Lublin, Xavier Montalbán, Carlo Pozzilli, Tatiana Scherz, Daniele D’Ambrosio, Philippe Linscheid, Andrea Vaclavkova, Magdalena Pirozek-Lawniczek, Hilke Kracker, Till Sprenger - JAMA Neurology 2021 cited by 218
- Hyperactivation of phosphatidylinositol-3 kinase promotes escape from hormone dependence in estrogen receptor–positive human breast cancer
Authors: Todd W. Miller, Bryan T. Hennessy, Ana M. González-Angulo, Emily M. Fox, Gordon B. Mills, Heidi Chen, Catherine Higham, Carlos Garcı́a-Echeverrı́a, Yu Shyr, Carlos L. Arteaga - Journal of Clinical Investigation 2010 cited by 545
- The biology of ovarian cancer: new opportunities for translation
Authors: Robert C. Bast, Bryan T. Hennessy, Gordon B. Mills - Nature reviews. Cancer 2009 cited by 1,370
- The energy sensing LKB1–AMPK pathway regulates p27kip1 phosphorylation mediating the decision to enter autophagy or apoptosis
Authors: Jiyong Liang, Shan Shao, Zhixiang Xu, Bryan T. Hennessy, Zhiyong Ding, Michelle D. Larrea, Seiji Kondo, Dan Dumont, Jordan U. Gutterman, Cheryl L. Walker, Joyce M. Slingerland, Gordon B. Mills - Nature Cell Biology 2007 cited by 851
- Correlating transcriptional networks to breast cancer survival: a large-scale coexpression analysis
Authors: Colin Clarke, Stephen F. Madden, Padraig Doolan, Sinéad Aherne, Helena Joyce, Lorraine O’Driscoll, William M. Gallagher, Bryan T. Hennessy, M. Moriarty, John Crown, Susan Kennedy, Martin Clynes - Carcinogenesis 2013 cited by 877
- Ovarian cancer
Authors: Bryan T. Hennessy, Robert L. Coleman, Maurie Markman - The Lancet 2009 cited by 652
- Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer
Authors: Suzanne A. Eccles, Eric O. Aboagye, Simak Ali, Annie S. Anderson, Jo Armes, Fedor Berditchevski, Jeremy P. Blaydes, Keith Brennan, Nicola J. Brown, Helen E. Bryant, Nigel Bundred, Joy Burchell, Anna Campbell, Jason S. Carroll, Robert B. Clarke, Charlotte E. Coles, Gary Cook, Angela Cox, Nicola J. Curtin, Lodewijk V. Dekker, Isabel dos‐Santos‐Silva, Stephen W. Duffy, Douglas F. Easton, Diana M Eccles, Dylan R. Edwards, Joanne Edwards, D. Gareth Evans, Deborah Fenlon, James M. Flanagan, Claire Foster, William M. Gallagher, Montserrat García‐Closas, Julia M.W. Gee, Andy J Gescher, Vicky Goh, Ashley M. Groves, Amanda Harvey, Michelle Harvie, Bryan T. Hennessy, Stephen Hiscox, Ingunn Holen, Sacha J. Howell, Anthony Howell, Gill Hubbard, Nick Hulbert-Williams, Myra S. Hunter, Bharat Jasani, J. Louise Jones, Timothy J. Key, Cliona Kirwan, Anthony Kong, Ian Kunkler, Simon P. Langdon, Martin O. Leach, David J. Mann, John F. Marshall, Lesley Martin, Stewart G. Martin, J Macdougall, David Miles, William R. Miller, Joanna R. Morris, Sue Moss, Paul B. Mullan, Rachael Natrajan, James P.B. O’Connor, Rosemary O’Connor, Carlo Palmieri, Paul D.P. Pharoah, Emad A. Rakha, Elizabeth Reed, Simon P. Robinson, Erik Sahai, John Saxton, Peter Schmid, Matthew J. Smalley, Valerie Speirs, Robert C. Stein, Julia Stingl, Charles Streuli, Andrew Tutt, Galina Velikova, Rosemary A. Walker, Christine J. Watson, Kaye J. Williams, Leonie S. Young, Alastair M. Thompson - Breast Cancer Research 2013 cited by 426
- Tumor PIK3CA Genotype and Prognosis in Early-Stage Breast Cancer: A Pooled Analysis of Individual Patient Data
Authors: Dimitrios Zardavas, Luc te Marvelde, Roger L. Milne, Debora Fumagalli, George Fountzilas, Vassiliki Kotoula, Evangelia Razis, George Papaxoinis, Heikki Joensuu, Mary Ellen Moynahan, Bryan T. Hennessy, Ivan Bièche, Lao H. Saal, Olle Stål, Barry Iacopetta, Jeanette Dupont Jensen, Sandra A. O’Toole, Elena López‐Knowles, Mattia Barbaraeschi, Shinzaburo Noguchi, Hatem A. Azim, Enrique Lerma, Thomas Bachelot, Qing Wang, Gizeh Pérez‐Tenorio, Cornelis J.H. can de Velde, Daniel Rea, Vicky S. Sabine, John M.S. Bartlett, Christos Sotiriou, Stefan Michiels, Sherene Loi - Journal of Clinical Oncology 2018 cited by 147
- Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics
Authors: Bryan T. Hennessy, Ana-Maria Gonzalez-Angulo, Katherine Stemke‐Hale, Michael Z. Gilcrease, Savitri Krishnamurthy, Ju‐Seog Lee, Jane Fridlyand, Ayşegül A. Şahin, Roshan Agarwal, Corwin Joy, Wenbin Liu, David Stivers, Keith Baggerly, Mark Carey, Aňa Lluch, Carlos Monteagudo, Xiaping He, Victor Weigman, Cheng Fan, Juan Palazzo, Gabriel N. Hortobágyi, Laura K. Nolden, Nicholas J. Wang, Vicente Valero, Joe W. Gray, Charles M. Perou, Gordon B. Mills - Cancer Research 2009 cited by 857
- High Frequency of PIK3R1 and PIK3R2 Mutations in Endometrial Cancer Elucidates a Novel Mechanism for Regulation of PTEN Protein Stability
Authors: Lydia W.T. Cheung, Bryan T. Hennessy, Jie Li, Shuangxing Yu, Andrea P. Myers, Bojana Djordjevic, Yiling Lu, Katherine Stemke‐Hale, Mary D. Dyer, Fan Zhang, Zhenlin Ju, Lewis C. Cantley, Steven E. Scherer, Han Liang, Karen H. Lu, Russell R. Broaddus, Gordon B. Mills - Cancer Discovery 2011 cited by 472
- Genome-wide transcriptome profiling of homologous recombination DNA repair
Authors: Guang Peng, Curtis Chun-Jen Lin, Wei Mo, Hui Dai, Yun‐Yong Park, Soo Mi Kim, Yang Peng, Qianxing Mo, Stefan Siwko, Ruozhen Hu, Ju‐Seog Lee, Bryan T. Hennessy, Samir Hanash, Gordon B. Mills, Shiaw‐Yih Lin - Nature Communications 2014 cited by 228
- Survival with Trastuzumab Emtansine in Residual HER2-Positive Breast Cancer
Authors: Charles E. Geyer, M. Untch, Chiun‐Sheng Huang, Max S. Mano, Eleftherios P. Mamounas, Norman Wolmark, Priya Rastogi, Andreas Schneeweiß, Andrés Redondo, Hans Holger Fischer, Véronique D’Hondt, Alison Conlin, Valentina Guarneri, Irene Wapnir, Christian Jackisch, Claudia Arce-Salinas, Peter A. Fasching, Michael P. DiGiovanna, John Crown, Pia Wuelfing, Zhimin Shao, Elena Rota Caremoli, Hervé Bonnefoi, Bryan T. Hennessy, Ljiljana Stamatović, Hugo Castro‐Salguero, Adam Brufsky, Adam Knott, Asna Siddiqui, Chiara Lambertini, Thomas Boulet, Beatrice Nyawira, Eleonora Restuccia, Sibylle Loibl - New England Journal of Medicine 2025 cited by 115
- Effects of HER Family–targeting Tyrosine Kinase Inhibitors on Antibody-dependent Cell-mediated Cytotoxicity in HER2-expressing Breast Cancer
Authors: Denis M. Collins, Stephen F. Madden, Nicola Gaynor, Dalal AlSultan, Marion Le Gal, Alex J. Eustace, Kathy Gately, Clare Hughes, Anthony M. Davies, Thamir Mahgoub, Jo Ballot, Sinéad Toomey, Darran P. O’Connor, William M. Gallagher, Frankie A. Holmes, Virginia Espina, Lance A. Liotta, Bryan T. Hennessy, Kenneth J. O’Byrne, Max Hasmann, Birgit Bossenmaier, Norma O’Donovan, John Crown - Clinical Cancer Research 2020 cited by 76
- Reverse phase protein array: validation of a novel proteomic technology and utility for analysis of primary leukemia specimens and hematopoietic stem cells
Authors: Raoul Tibes, Yihua Qiu, Yiling Lu, Bryan T. Hennessy, Michael Andreeff, Gordon B. Mills, Steven M. Kornblau - Molecular Cancer Therapeutics 2006 cited by 758
- Subtype and pathway specific responses to anticancer compounds in breast cancer
Authors: Laura M. Heiser, Anguraj Sadanandam, Wen‐Lin Kuo, Stephen C. Benz, Theodore C. Goldstein, Sam Ng, William J. Gibb, Nicholas J. Wang, Safiyyah Ziyad, Frances Tong, Nora Bayani, Zhi Hu, Jessica I. Billig, Andrea Dueregger, Sophia Lewis, Lakshmi R. Jakkula, James E. Korkola, Steffen Durinck, François Pépin, Yinghui Guan, Elizabeth Purdom, Pierre Neuvial, Henrik Bengtsson, Kenneth W. Wood, Peter G. Smith, Lyubomir T. Vassilev, Bryan T. Hennessy, Joel Greshock, Kurtis E. Bachman, Mary Ann Hardwicke, John W. Park, Laurence J. Marton, Denise M. Wolf, Eric A. Collisson, Richard M. Neve, Gordon B. Mills, Terence P. Speed, Heidi S. Feiler, Richard Wooster, David Haussler, Joshua M. Stuart, Joe W. Gray, Paul T. Spellman - National Academy of Sciences, Proceedings of the National Academy of Sciences 2011 cited by 504
- Outcome After Pathologic Complete Eradication of Cytologically Proven Breast Cancer Axillary Node Metastases Following Primary Chemotherapy
Authors: Bryan T. Hennessy, Gabriel N. Hortobágyi, Roman Rouzier, Henry M. Kuerer, Nour Sneige, Aman U. Buzdar, Shu Wan Kau, Bruno D. Fornage, Ayşegül A. Şahin, Kristine Broglio, S. Eva Singletary, Vicente Valero - Journal of Clinical Oncology 2005 cited by 422
- Adipose tissue derived stem cells differentiate into carcinoma-associated fibroblast-like cells under the influence of tumor derived factors.
Authors: Constantin Jotzu, Eckhard Alt, Gabriel Welte, Jie Li, Bryan T. Hennessy, Eswaran Devarajan, Srinivasalu Krishnappa, Severin Pinilla, Lilly Droll, Yao‐Hua Song - Analytical Cellular Pathology 2010 cited by 236
