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Byron Caughey

Active 1988–2025

142
Papers
24,970
Citations
90
h-index
138
i10-index

Citations

Citations per year for Byron Caughey1982: 1 citations1985: 4 citations1989: 3 citations1990: 18 citations1991: 13 citations1992: 38 citations1993: 39 citations1994: 59 citations1995: 130 citations1996: 81 citations1997: 149 citations1998: 110 citations1999: 146 citations2000: 151 citations2001: 199 citations2002: 181 citations2003: 237 citations2004: 272 citations2005: 150 citations2006: 224 citations2007: 215 citations2008: 202 citations2009: 212 citations2010: 210 citations2011: 180 citations2012: 152 citations2013: 106 citations2014: 115 citations2015: 106 citations2016: 177 citations2017: 122 citations2018: 140 citations2019: 486 citations2020: 562 citations2021: 624 citations2022: 687 citations2023: 433 citations2024: 753 citations2025: 346 citations2026: 12 citations1983–1984: no citations, so these years are not shown1986–1988: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 1,746 citing papers, 31% of this breakdownUnited Kingdom: 548 citing papers, 9.7% of this breakdownGermany: 440 citing papers, 7.8% of this breakdownItaly: 376 citing papers, 6.7% of this breakdownFrance: 240 citing papers, 4.3% of this breakdownCanada: 229 citing papers, 4.1% of this breakdownJapan: 180 citing papers, 3.2% of this breakdownChina: 170 citing papers, 3% of this breakdownSpain: 169 citing papers, 3% of this breakdownSweden: 161 citing papers, 2.9% of this breakdownSwitzerland: 155 citing papers, 2.8% of this breakdownAustralia: 107 citing papers, 1.9% of this breakdown
0%31%Other 19.6%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology54.6%
  • Medicine36.8%
  • Neuroscience3.5%
  • Materials Science1.4%
  • Chemistry0.9%
  • Immunology and Microbiology0.6%
  • Other2.2%

Topics

  • Prion Diseases and Protein Misfolding18.8%
  • Alzheimer's disease research and treatments11.4%
  • Neurological diseases and metabolism9.2%
  • Parkinson's Disease Mechanisms and Treatments6.5%
  • Trace Elements in Health6.4%
  • Neurological disorders and treatments3.1%
  • Other44.6%

Coauthors

All papers

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  1. Ultrasensitive RT-QuIC assay with high sensitivity and specificity for Lewy body-associated synucleinopathies

    Authors: Marcello Rossi, Niccolò Candelise, Simone Baiardi, Sabina Capellari, Giulia Giannini, Christina D. Orrú, Elena Antelmi, Angela Mammana, Andrew G. Hughson, Giovanna Calandra–Buonaura, Anna Ladogana, Giuseppe Plazzi, Pietro Cortelli, Byron Caughey, Piero Parchi - Acta Neuropathologica 2020 cited by 474

  2. High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson’s disease

    Authors: Marco J. Russo, Christina D. Orrú, Luis Concha‐Marambio, Simone Giaisi, Bradley R. Groveman, Carly M. Farris, Bret Holguin, Andrew G. Hughson, David-Erick Lafontant, Chelsea Caspell‐Garcia, Christopher S. Coffey, J Mollon, Samantha J. Hutten, Kalpana Merchant, Roland G. Heym, Claudio Soto, Byron Caughey, Un Jung Kang - Acta Neuropathologica Communications 2021 cited by 259

  3. Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC

    Authors: Bradley R. Groveman, Christina D. Orrú, Andrew G. Hughson, Lynne D. Raymond, Gianluigi Zanusso, Bernardino Ghetti, Katrina J. Campbell, Jiri Safar, Douglas Galasko, Byron Caughey - Acta Neuropathologica Communications 2018 cited by 431

  4. Skin α-Synuclein Aggregation Seeding Activity as a Novel Biomarker for Parkinson Disease

    Authors: Zerui Wang, Katelyn Becker, Vincenzo Donadio, Sandra L. Siedlak, Jue Yuan, Masih Rezaee, Alex Incensi, Anastasia Kuzkina, Christina D. Orrú, Curtis Tatsuoka, Rocco Liguori, Steven A. Gunzler, Byron Caughey, María E. Jiménez‐Capdeville, Xiongwei Zhu, Kathrin Doppler, Li Cui, Shu G. Chen, Jiyan Ma, Wen‐Quan Zou - JAMA Neurology 2020 cited by 254

  5. Performance of αSynuclein RT-QuIC in relation to neuropathological staging of Lewy body disease

    Authors: Sara Hall, Christina D. Orrú, Geidy E. Serrano, Douglas Galasko, Andrew G. Hughson, Bradley R. Groveman, Charles H. Adler, Thomas G. Beach, Byron Caughey, Oskar Hansson - Acta Neuropathologica Communications 2022 cited by 121

  6. Rapid End-Point Quantitation of Prion Seeding Activity with Sensitivity Comparable to Bioassays

    Authors: Jason M. Wilham, Christina D. Orrú, Richard A. Bessen, Ryuichiro Atarashi, Kazunori Sano, Brent Race, Kimberly Meade‐White, Lara M. Taubner, Andrew Timmes, Byron Caughey - PLoS Pathogens 2010 cited by 510

  7. High-resolution structure and strain comparison of infectious mammalian prions

    Authors: Allison Kraus, Forrest Hoyt, Cindi L. Schwartz, Bryan Hansen, Efrosini Artikis, Andrew G. Hughson, Gregory J. Raymond, Brent Race, Gerald S. Baron, Byron Caughey - Molecular Cell 2021 cited by 253

  8. Biomarkers and diagnostic guidelines for sporadic Creutzfeldt-Jakob disease

    Authors: Péter Hermann, Brian S. Appleby, Jean‐Philippe Brandel, Byron Caughey, Steven Collins, Michael D. Geschwind, Alison Green, Stéphane Haı̈k, Gábor G. Kovács, Anna Ladogana, Franc Llorens, Simon Mead, Noriyuki Nishida, Suvankar Pal, Piero Parchi, Maurizio Pocchiari, Katsuya Satoh, Gianluigi Zanusso, Inga Zerr - The Lancet Neurology 2021 cited by 340

  9. A rapid α‐synuclein seed assay of Parkinson’s disease CSF panel shows high diagnostic accuracy

    Authors: Christina D. Orrú, C. Thong, Andrew G. Hughson, Bradley R. Groveman, Ankit Srivastava, Douglas Galasko, Rachel Angers, Patrick Downey, Karen Crawford, Samantha J. Hutten, Un Jung Kang, Byron Caughey - Annals of Clinical and Translational Neurology 2020 cited by 99

  10. Diagnostic Value of the CSF α-Synuclein Real-Time Quaking-Induced Conversion Assay at the Prodromal MCI Stage of Dementia With Lewy Bodies

    Authors: Marcello Rossi, Simone Baiardi, Charlotte E. Teunissen, Corinne Quadalti, Marleen van de Beek, Angela Mammana, Michelangelo Stanzani-Maserati, Wiesje M. van der Flier, Luisa Sambati, Corrado Zenesini, Byron Caughey, Sabina Capellari, Afina W. Lemstra, Piero Parchi - Neurology 2021 cited by 120

  11. 4-Repeat tau seeds and templating subtypes as brain and CSF biomarkers of frontotemporal lobar degeneration

    Authors: Eri Saijo, Michael A. Metrick, Shunsuke Koga, Piero Parchi, Irene Litvan, Salvatore Spina, Adam L. Boxer, Julio C. Rojas, Douglas Galasko, Allison Kraus, Marcello Rossi, Kathy L. Newell, Gianluigi Zanusso, Lea T. Grinberg, William W. Seeley, Bernardino Ghetti, Dennis W. Dickson, Byron Caughey - Acta Neuropathologica 2019 cited by 171

  12. RT-QuIC and Related Assays for Detecting and Quantifying Prion-like Pathological Seeds of α-Synuclein

    Authors: Ankit Srivastava, Parvez Alam, Byron Caughey - Biomolecules 2022 cited by 55

  13. Cryo-EM structure of anchorless RML prion reveals variations in shared motifs between distinct strains

    Authors: Forrest Hoyt, Heidi G. Standke, Efrosini Artikis, Cindi L. Schwartz, Bryan Hansen, Kunpeng Li, Andrew G. Hughson, Matteo Manca, Olivia R. Thomas, Gregory J. Raymond, Brent Race, Gerald S. Baron, Byron Caughey, Allison Kraus - Nature Communications 2022 cited by 109

  14. Seeding selectivity and ultrasensitive detection of tau aggregate conformers of Alzheimer disease

    Authors: Allison Kraus, Eri Saijo, Michael A. Metrick, Kathy L. Newell, Christina J. Sigurdson, Gianluigi Zanusso, Bernardino Ghetti, Byron Caughey - Acta Neuropathologica 2018 cited by 146

  15. Cryo-EM of prion strains from the same genotype of host identifies conformational determinants

    Authors: Forrest Hoyt, Parvez Alam, Efrosini Artikis, Cindi L. Schwartz, Andrew G. Hughson, Brent Race, Chase Baune, Gregory J. Raymond, Gerald S. Baron, Allison Kraus, Byron Caughey - PLoS Pathogens 2022 cited by 60

  16. A single ultrasensitive assay for detection and discrimination of tau aggregates of Alzheimer and Pick diseases

    Authors: Michael A. Metrick, Natalia Ferreira, Eri Saijo, Allison Kraus, Kathy L. Newell, Gianluigi Zanusso, Michele Vendruscolo, Bernardino Ghetti, Byron Caughey - Acta Neuropathologica Communications 2020 cited by 124

  17. PROTOFIBRILS, PORES, FIBRILS, AND NEURODEGENERATION: Separating the Responsible Protein Aggregates from The Innocent Bystanders

    Authors: Byron Caughey, Peter T. Lansbury - Annual Review of Neuroscience 2003 cited by 1,646

  18. Million-fold sensitivity enhancement in proteopathic seed amplification assays for biospecimens by Hofmeister ion comparisons

    Authors: Michael A. Metrick, Natalia Ferreira, Eri Saijo, Andrew G. Hughson, Allison Kraus, Christina D. Orrú, Michael W. Miller, Gianluigi Zanusso, Bernardino Ghetti, Michele Vendruscolo, Byron Caughey - National Academy of Sciences, Proceedings of the National Academy of Sciences 2019 cited by 108

  19. Ultrasensitive and selective detection of 3-repeat tau seeding activity in Pick disease brain and cerebrospinal fluid

    Authors: Eri Saijo, Bernardino Ghetti, Gianluigi Zanusso, Adrian L. Oblak, Jennifer L. Furman, Marc I. Diamond, Allison Kraus, Byron Caughey - Acta Neuropathologica 2017 cited by 148

  20. Prion seeding activity and infectivity in skin samples from patients with sporadic Creutzfeldt-Jakob disease

    Authors: Christina D. Orrú, Jue Yuan, Brian S. Appleby, Baiya Li, Yu Li, Dane Winner, Zerui Wang, Yi-An Zhan, Mark Rodgers, Jason Rarick, Robert E. Wyza, Tripti Joshi, Gong-Xian Wang, Mark L. Cohen, Shulin Zhang, Bradley R. Groveman, Robert B. Petersen, James W. Ironside, Miguel E. Quiñones‐Mateu, Jiri Safar, Qingzhong Kong, Byron Caughey, Wen‐Quan Zou - Science Translational Medicine 2017 cited by 146

  21. Discovery of potent inhibitors of α-synuclein aggregation using structure-based iterative learning

    Authors: Robert I. Horne, Ewa A. Andrzejewska, Parvez Alam, Z. Faidon Brotzakis, Ankit Srivastava, Alice Aubert, Magdalena Nowinska, Rebecca C. Gregory, Roxine Staats, Andrea Possenti, Sean Chia, Pietro Sormanni, Bernardino Ghetti, Byron Caughey, Tuomas P. J. Knowles, Michele Vendruscolo - Nature Chemical Biology 2024 cited by 45

  22. Antisense oligonucleotides extend survival of prion-infected mice

    Authors: Gregory J. Raymond, Hien Zhao, Brent Race, Lynne D. Raymond, Katie Williams, Eric E. Swayze, Samantha Graffam, Jason Le, Tyler Caron, Jacquelyn Stathopoulos, Rhonda O’Keefe, Lori Lubke, Andrew G. Reidenbach, Allison Kraus, Stuart L. Schreiber, Curt Mazur, Deborah E. Cabin, Jeffrey B. Carroll, Eric Vallabh Minikel, Holly Kordasiewicz, Byron Caughey, Sonia M. Vallabh - JCI Insight 2019 cited by 147

  23. Rapid and Sensitive RT-QuIC Detection of Human Creutzfeldt-Jakob Disease Using Cerebrospinal Fluid

    Authors: Christina D. Orrú, Bradley R. Groveman, Andrew G. Hughson, Gianluigi Zanusso, Michael B. Coulthart, Byron Caughey - mBio 2015 cited by 246

  24. Detection of prions in skin punch biopsies of Creutzfeldt–Jakob disease patients

    Authors: Angela Mammana, Simone Baiardi, Marcello Rossi, Alessia Franceschini, Vincenzo Donadio, Sabina Capellari, Byron Caughey, Piero Parchi - Annals of Clinical and Translational Neurology 2020 cited by 66