Christopher J. Marshall
Active 1983–2025
- 82
- Papers
- 37,904
- Citations
- 73
- h-index
- 80
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology61.7%
- Medicine29.4%
- Immunology and Microbiology2.7%
- Neuroscience2.3%
- Computer Science0.9%
- Chemistry0.6%
- Other2.4%
Topics
- Melanoma and MAPK Pathways8.3%
- Protein Kinase Regulation and GTPase Signaling6.5%
- Cellular Mechanics and Interactions2.9%
- Cancer-related Molecular Pathways2.5%
- PI3K/AKT/mTOR signaling in cancer2.3%
- Computational Drug Discovery Methods1.9%
- Other75.6%
Coauthors
- Richard Marais10
- Hugh F. Paterson9
- Erik Sahai8
- Hugh Paterson8
- Michael F. Olson6
- Afshan McCarthy5
- Amine Sadok5
- Georgia Mavria5
- Maggie Yeo5
- Alan Ashworth4
- Alan Hall4
- Calum Stewart4
- Sally J. Leevers4
- Steven Hooper4
- Victoria Sanz‐Moreno4
- Antonio Chiloeches3
- Caroline J. Springer3
- Clive Mason3
- Faraz K. Mardakheh3
- Gordon Stamp3
- John F. Hancock3
- Peter H. Sugden3
- Rebecca E. Campbell3
- Rebecca Wilson3
All papers
- Mutations of the BRAF gene in human cancer
Authors: Helen Davies, Graham R. Bignell, Charles Cox, Philip Stephens, Sarah Edkins, Sheila Clegg, Jon W. Teague, Hayley Woffendin, Mathew J. Garnett, William Bottomley, Neil M. Davis, Ed Dicks, Rebecca Ewing, Yvonne Floyd, Kristian Gray, Sarah Hall, Rachel Hawes, Jaime Hughes, Vivian Kosmidou, Andrew Menzies, Catherine Mould, Adrian G. Parker, Claire Stevens, Stephen Watt, Steven Hooper, Rebecca Wilson, Hiran Jayatilake, Barry A. Gusterson, Colin Cooper, Janet Shipley, Darren Hargrave, Katherine Pritchard-Jones, Norman J. Maitland, Georgia Chenevix‐Trench, Gregory J. Riggins, Darell D. Bigner, Giuseppe Palmieri, Antonio Cossu, Adrienne M. Flanagan, Andrew G. Nicholson, Judy Ho, Suet Yi Leung, Siu Tsan Yuen, Barbara L. Weber, Hilliard F. Seigler, Timothy L. Darrow, Hugh Paterson, Richard Marais, Christopher J. Marshall, Richard Wooster, Michael R. Stratton, P. Andrew Futreal - Nature 2002 cited by 10,737
- Mechanism of Activation of the RAF-ERK Signaling Pathway by Oncogenic Mutations of B-RAF
Authors: Paul Wan, Mathew J. Garnett, S. Mark Roe, Sharlene Lee, Dan Niculescu‐Duvaz, Valerie M. Good, Cancer Genome Project, Chris M. Jones, Christopher J. Marshall, Caroline J. Springer, David Barford, Richard Marais - Cell 2004 cited by 2,815
- Rac Activation and Inactivation Control Plasticity of Tumor Cell Movement
Authors: Victoria Sanz‐Moreno, Gilles Gadéa, Jessica Ahn, Hugh Paterson, Pierfrancesco Marra, Sophie Pinner, Erik Sahai, Christopher J. Marshall - Cell 2008 cited by 976
- Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis
Authors: Erik Sahai, Christopher J. Marshall - Nature Cell Biology 2003 cited by 1,138
- A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane
Authors: John F. Hancock, Hugh Paterson, Christopher J. Marshall - Cell 1990 cited by 1,076
- RHO–GTPases and cancer
Authors: Erik Sahai, Christopher J. Marshall - Nature reviews. Cancer 2002 cited by 1,387
- Enhancement of a robust arcuate GABAergic input to gonadotropin-releasing hormone neurons in a model of polycystic ovarian syndrome
Authors: Aleisha M. Moore, Mel Prescott, Christopher J. Marshall, Siew Hoong Yip, Rebecca E. Campbell - National Academy of Sciences, Proceedings of the National Academy of Sciences 2014 cited by 213
- All ras proteins are polyisoprenylated but only some are palmitoylated
Authors: John F. Hancock, Anthony I. Magee, Julie E. Childs, Christopher J. Marshall - Cell 1989 cited by 1,823
- Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane
Authors: Sally J. Leevers, Hugh F. Paterson, Christopher J. Marshall - Nature 1994 cited by 1,017
- Serine and tyrosine phosphorylations cooperate in Raf‐1, but not B‐Raf activation
Authors: Clive Mason, Caroline J. Springer, Robert G Cooper, Giulio Superti‐Furga, Christopher J. Marshall, Richard Marais - The EMBO Journal 1999 cited by 457
- ERK-MAPK signaling opposes Rho-kinase to promote endothelial cell survival and sprouting during angiogenesis
Authors: Georgia Mavria, Yvonne Vercoulen, Maggie Yeo, Hugh Paterson, Maria Karasarides, Richard Marais, D. K. Bird, Christopher J. Marshall - Cancer Cell 2006 cited by 345
- Rho-associated kinase (ROCK) function is essential for cell cycle progression, senescence and tumorigenesis
Authors: Sandra Kümper, Faraz K. Mardakheh, Afshan McCarthy, Maggie Yeo, Gordon Stamp, Angela Paul, Jonathan D. Worboys, Amine Sadok, Claus Jørgensen, Sabrina Guichard, Christopher J. Marshall - eLife 2016 cited by 186
- Rho Kinase Inhibitors Block Melanoma Cell Migration and Inhibit Metastasis
Authors: Amine Sadok, Afshan McCarthy, John Caldwell, Ian Collins, Michelle D. Garrett, Maggie Yeo, Steven Hooper, Erik Sahai, Sandra Kuemper, Faraz K. Mardakheh, Christopher J. Marshall - Cancer Research 2015 cited by 133
- Differential Regulation of Raf-1, A-Raf, and B-Raf by Oncogenic Ras and Tyrosine Kinases
Authors: Richard Marais, Yvonne Light, Hugh F. Paterson, Clive Mason, Christopher J. Marshall - Journal of Biological Chemistry 1997 cited by 460
- ROCK and Dia have opposing effects on adherens junctions downstream of Rho
Authors: Erik Sahai, Christopher J. Marshall - Nature Cell Biology 2002 cited by 458
- ERK-MAPK signaling coordinately regulates activity of Rac1 and RhoA for tumor cell motility
Authors: Emmanuel Vial, Erik Sahai, Christopher J. Marshall - Cancer Cell 2003 cited by 410
- Cdc42–MRCK and Rho–ROCK signalling cooperate in myosin phosphorylation and cell invasion
Authors: Simon Wilkinson, Hugh F. Paterson, Christopher J. Marshall - Nature Cell Biology 2005 cited by 388
- Activation of a Classic Hunger Circuit Slows Luteinizing Hormone Pulsatility
Authors: Eulalia A. Coutinho, Melanie Prescott, Sabine Hessler, Christopher J. Marshall, Allan E. Herbison, Rebecca E. Campbell - Neuroendocrinology 2019 cited by 47
- VE-Cadherin-Mediated Cell-Cell Interaction Suppresses Sprouting via Signaling to MLC2 Phosphorylation
Authors: Sabu Abraham, Margaret Yeo, Mercedes Montero‐Balaguer, Hugh Paterson, Elisabetta Dejana, Christopher J. Marshall, Georgia Mavria - Current Biology 2009 cited by 167
- RAS and RHO GTPases in G1-phase cell-cycle regulation
Authors: Mathew L. Coleman, Christopher J. Marshall, Michael F. Olson - Nature Reviews Molecular Cell Biology 2004 cited by 353
- A screen for morphological complexity identifies regulators of switch-like transitions between discrete cell shapes
Authors: Zheng Yin, Amine Sadok, Heba Sailem, Afshan McCarthy, Xiaofeng Xia, Fuhai Li, Mar Arias-García, Louise Evans, Alexis R. Barr, Norbert Perrimon, Christopher J. Marshall, Stephen T.C. Wong, Chris Bakal - Nature Cell Biology 2013 cited by 196
- A Rac/Cdc42 exchange factor complex promotes formation of lateral filopodia and blood vessel lumen morphogenesis
Authors: Sabu Abraham, Margherita Scarcia, Richard D. Bagshaw, Kathryn McMahon, Gary Grant, Tracey J. Harvey, Maggie Yeo, Filomena Esteves, Helene Thygesen, Pamela F. Jones, Valerie Speirs, Andrew M. Hanby, Peter J. Selby, Mihaela Lorger, T. Neil Dear, Tony Pawson, Christopher J. Marshall, Georgia Mavria - Nature Communications 2015 cited by 85
- MAP kinase kinase kinase, MAP kinase kinase and MAP kinase
Authors: Christopher J. Marshall - Current Opinion in Genetics & Development 1994 cited by 1,003
- Investigating the NPY/AgRP/GABA to GnRH Neuron Circuit in Prenatally Androgenized PCOS-Like Mice
Authors: Christopher J. Marshall, Melanie Prescott, Rebecca E. Campbell - Journal of the Endocrine Society 2020 cited by 25
