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Christopher W. Murray

Active 1988–2024

83
Papers
19,107
Citations
59
h-index
80
i10-index

Citations

Citations per year for Christopher W. Murray1958: 2 citations1968: 2 citations1977: 1 citations1981: 1 citations1983: 1 citations1986: 4 citations1987: 1 citations1990: 3 citations1991: 4 citations1992: 6 citations1993: 16 citations1994: 15 citations1995: 24 citations1996: 35 citations1997: 26 citations1998: 37 citations1999: 42 citations2000: 71 citations2001: 51 citations2002: 72 citations2003: 91 citations2004: 134 citations2005: 209 citations2006: 300 citations2007: 301 citations2008: 329 citations2009: 394 citations2010: 364 citations2011: 451 citations2012: 432 citations2013: 321 citations2014: 287 citations2015: 324 citations2016: 303 citations2017: 226 citations2018: 315 citations2019: 501 citations2020: 600 citations2021: 526 citations2022: 459 citations2023: 309 citations2024: 508 citations2025: 299 citations2026: 31 citations1959–1967: no citations, so these years are not shown1969–1976: no citations, so these years are not shown1978–1980: no citations, so these years are not shown1982: no citations, so this year is not shown1984–1985: no citations, so these years are not shown1988–1989: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 1,866 citing papers, 23.3% of this breakdownUnited Kingdom: 808 citing papers, 10.1% of this breakdownChina: 692 citing papers, 8.6% of this breakdownGermany: 519 citing papers, 6.5% of this breakdownItaly: 356 citing papers, 4.4% of this breakdownIndia: 311 citing papers, 3.9% of this breakdownFrance: 297 citing papers, 3.7% of this breakdownSwitzerland: 257 citing papers, 3.2% of this breakdownSpain: 197 citing papers, 2.5% of this breakdownBrazil: 187 citing papers, 2.3% of this breakdownCanada: 156 citing papers, 2% of this breakdownJapan: 153 citing papers, 1.9% of this breakdown
0%23.3%Other 27.6%

Institutions

Fields

  • Computer Science44.3%
  • Biochemistry, Genetics and Molecular Biology27%
  • Medicine15.2%
  • Chemistry4.7%
  • Materials Science2%
  • Physics and Astronomy1.5%
  • Other5.3%

Topics

  • Computational Drug Discovery Methods20%
  • Protein Structure and Dynamics9.1%
  • Chemical Synthesis and Analysis3.3%
  • Click Chemistry and Applications2.9%
  • Enzyme Structure and Function2.6%
  • Microbial Natural Products and Biosynthesis2.3%
  • Other59.8%

Coauthors

All papers

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  1. Improved protein–ligand docking using GOLD

    Authors: Marcel L. Verdonk, Jason C. Cole, Michael J. Hartshorn, Christopher W. Murray, Richard D. Taylor - Proteins Structure Function and Bioinformatics 2003 cited by 3,042

  2. A ‘Rule of Three’ for fragment-based lead discovery?

    Authors: Miles Congreve, Robin A. E. Carr, Christopher W. Murray, Harren Jhoti - Drug Discovery Today 2003 cited by 1,355

  3. The rise of fragment-based drug discovery

    Authors: Christopher W. Murray, David C. Rees - Nature Chemistry 2009 cited by 794

  4. Diverse, High-Quality Test Set for the Validation of Protein−Ligand Docking Performance

    Authors: Michael J. Hartshorn, Marcel L. Verdonk, Gianni Chessari, Suzanne Brewerton, Wijnand T. M. Mooij, Paul N. Mortenson, Christopher W. Murray - Journal of Medicinal Chemistry 2007 cited by 642

  5. Discovery and Pharmacological Characterization of JNJ-42756493 (Erdafitinib), a Functionally Selective Small-Molecule FGFR Family Inhibitor

    Authors: Timothy Perera, Eleonora Jovcheva, Laurence Mévellec, Jorge Vialard, Desiree De Lange, Tinne Verhulst, Caroline Paulussen, Kelly Van De Ven, Peter King, Eddy Freyne, David C. Rees, Matthew Squires, Gordon Saxty, Martin Pagé, Christopher W. Murray, Ron Gilissen, George A. Ward, Neil T. Thompson, David R. Newell, Na Cheng, Liang Xie, Jennifer Yang, Suso Platero, Jayaprakash D. Karkera, Christopher Moy, Patrick Angibaud, Sylvie Laquerre, Matthew V. Lorenzi - Molecular Cancer Therapeutics 2017 cited by 340

  6. Empirical scoring functions: I. The development of a fast empirical scoring function to estimate the binding affinity of ligands in receptor complexes

    Authors: Matthew D. Eldridge, Christopher W. Murray, Timothy R. Auton, Gaia Valeria Paolini, Roger P. Mee - Journal of Computer-Aided Molecular Design, J. Comput. Aided Mol. Des. 1997 cited by 1,681

  7. The 'rule of three' for fragment-based drug discovery: where are we now?

    Authors: Harren Jhoti, Glyn Williams, David C. Rees, Christopher W. Murray - Nature Reviews Drug Discovery 2013 cited by 325

  8. Fragment-based lead discovery

    Authors: David C. Rees, Miles Congreve, Christopher W. Murray, Robin A. E. Carr - Nature Reviews Drug Discovery 2004 cited by 796

  9. The AMBRA1 E3 ligase adaptor regulates the stability of cyclin D

    Authors: Andrea C. Chaikovsky, Chuan Li, Edwin E. Jeng, Samuel Loebell, Myung Chang Lee, Christopher W. Murray, Ran Cheng, János Demeter, Danielle L. Swaney, Sihan Chen, Billy W. Newton, Jeffrey R. Johnson, Alexandros P. Drainas, Yan Ting Shue, José A. Seoane, Preethi Srinivasan, Andy He, Akihiro Yoshida, Susan Q. Hipkins, Edel M. McCrea, Carson D. Poltorack, Nevan J. Krogan, J. Alan Diehl, Christina S. Kong, Peter K. Jackson, Christina Curtis, Dmitri A. Petrov, Michael C. Bassik, Monte M. Winslow, Julien Sage - Nature 2021 cited by 167

  10. Phagocytosis increases an oxidative metabolic and immune suppressive signature in tumor macrophages

    Authors: Michael Gonzalez, Daniel Lu, Maryam Yousefi, Ashley V. Kroll, Chen Hao Lo, Carlos G. Briseño, J. E. Vivienne Watson, Sergey V. Novitskiy, Vanessa Arias, Hong Zhou, Andres Plata Stapper, Min K. Tsai, Emily L. Ashkin, Christopher W. Murray, Chi-Ming Li, Monte M. Winslow, Kristin V. Tarbell - The Journal of Experimental Medicine 2023 cited by 62

  11. Design Principles for Fragment Libraries: Maximizing the Value of Learnings from Pharma Fragment-Based Drug Discovery (FBDD) Programs for Use in Academia

    Authors: György M. Keserű, Daniel A. Erlanson, György G. Ferenczy, Michael M. Hann, Christopher W. Murray, Stephen D. Pickett - Journal of Medicinal Chemistry 2016 cited by 233

  12. Fragment-Based Lead Discovery Using X-ray Crystallography

    Authors: Michael J. Hartshorn, Christopher W. Murray, Anne Cleasby, Martyn Frederickson, Ian J. Tickle, Harren Jhoti - Journal of Medicinal Chemistry 2004 cited by 423

  13. Modeling Water Molecules in Protein−Ligand Docking Using GOLD

    Authors: Marcel L. Verdonk, Gianni Chessari, Jason C. Cole, Michael J. Hartshorn, Christopher W. Murray, J. Willem M. Nissink, Richard D. Taylor, Robin Taylor - Journal of Medicinal Chemistry 2005 cited by 390

  14. An LKB1–SIK Axis Suppresses Lung Tumor Growth and Controls Differentiation

    Authors: Christopher W. Murray, Jennifer J. Brady, Min K. Tsai, Chuan Li, Ian P. Winters, Rui Tang, Laura Andrejka, K. Rosanna, Christian A. Kunder, Pauline Chu, Monte M. Winslow - Cancer Discovery 2019 cited by 112

  15. Discovery of (2,4-Dihydroxy-5-isopropylphenyl)-[5-(4-methylpiperazin-1-ylmethyl)-1,3-dihydroisoindol-2-yl]methanone (AT13387), a Novel Inhibitor of the Molecular Chaperone Hsp90 by Fragment Based Drug Design

    Authors: Andrew Woodhead, Hayley C. Angove, Maria G. Carr, Gianni Chessari, Miles Congreve, Joseph E. Coyle, José Cosme, Brent Graham, Philip J. Day, Robert Downham, Lynsey Fazal, Ruth E. Feltell, Eva Figueroa, Martyn Frederickson, Jonathan J. Lewis, Rachel McMenamin, Christopher W. Murray, Alistair O’Brien, Lina M. Parra, Sahil Patel, Theresa R. Phillips, David C. Rees, Sharna J. Rich, Donna-Michelle Smith, Gary Trewartha, M. Vinković, Brian Williams, Alison J.‐A. Woolford - Journal of Medicinal Chemistry 2010 cited by 263

  16. A successful collaboration between academia, biotech and pharma led to discovery of erdafitinib, a selective FGFR inhibitor recently approved by the FDA

    Authors: Christopher W. Murray, David R. Newell, Patrick Angibaud - MedChemComm 2019 cited by 79

  17. Comparing protein–ligand docking programs is difficult

    Authors: Jason C. Cole, Christopher W. Murray, J. Willem M. Nissink, Richard D. Taylor, Richard D. Taylor, Robin Taylor, Robin Taylor - Proteins Structure Function and Bioinformatics 2005 cited by 365

  18. Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design

    Authors: Marc O’Reilly, Anne Cleasby, Thomas G. Davies, Richard J. Hall, R. Frederick Ludlow, Christopher W. Murray, Dominic Tisi, Harren Jhoti - Drug Discovery Today 2019 cited by 97

  19. Fragment-based drug discovery: opportunities for organic synthesis

    Authors: Jeffrey D. St. Denis, Richard J. Hall, Christopher W. Murray, Tom D. Heightman, David C. Rees - RSC Medicinal Chemistry 2020 cited by 73

  20. A versatile system to record cell-cell interactions

    Authors: Rui Tang, Christopher W. Murray, Ian L. Linde, Nicholas J. Kramer, Zhonglin Lyu, Min K. Tsai, Leo C. Chen, Hongchen Cai, Aaron D. Gitler, Edgar G. Engleman, Wonjae Lee, Monte M. Winslow - eLife 2020 cited by 49

  21. Multiplexed screens identify RAS paralogues HRAS and NRAS as suppressors of KRAS-driven lung cancer growth

    Authors: Rui Tang, Emily G. Shuldiner, Marcus R. Kelly, Christopher W. Murray, Jess D. Hebert, Laura Andrejka, Min K. Tsai, Nicholas W. Hughes, Mitchell I. Parker, Hongchen Cai, Yaocheng Li, Geoffrey M. Wahl, Roland L. Dunbrack, Peter K. Jackson, Dmitri A. Petrov, Monte M. Winslow - Nature Cell Biology 2023 cited by 33

  22. Efficient exploration of chemical space by fragment-based screening

    Authors: Richard J. Hall, Paul N. Mortenson, Christopher W. Murray - Progress in Biophysics and Molecular Biology 2014 cited by 164

  23. Validity of Ligand Efficiency Metrics

    Authors: Christopher W. Murray, Daniel A. Erlanson, Andrew L. Hopkins, György M. Keserű, Paul D. Leeson, David C. Rees, Charles H. Reynolds, Nicola J. Richmond - ACS Medicinal Chemistry Letters 2014 cited by 135

  24. Docking Performance of Fragments and Druglike Compounds

    Authors: Marcel L. Verdonk, Ilenia Giangreco, Richard J. Hall, Oliver Korb, Paul N. Mortenson, Christopher W. Murray - Journal of Medicinal Chemistry 2011 cited by 127