Curtis D. Klaassen
Active 1966–2025
- 233
- Papers
- 32,717
- Citations
- 115
- h-index
- 228
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine35.9%
- Biochemistry, Genetics and Molecular Biology26.6%
- Environmental Science13.4%
- Pharmacology, Toxicology and Pharmaceutics7.8%
- Nursing6.2%
- Agricultural and Biological Sciences2.9%
- Other7.2%
Topics
- Drug Transport and Resistance Mechanisms7.4%
- Trace Elements in Health4.4%
- Genomics, phytochemicals, and oxidative stress4.3%
- Heavy Metal Exposure and Toxicity4.2%
- Liver Disease Diagnosis and Treatment3.2%
- Pharmacogenetics and Drug Metabolism3.1%
- Other73.4%
Coauthors
- Jie Liu27
- D. Belsito23
- James G. Marks23
- Paul W. Snyder23
- Ronald C. Shank23
- Thomas J. Slaga23
- Wilma F. Bergfeld23
- D.C. Liebler21
- Ronald A. Hill19
- Bart Heldreth18
- Lauren M. Aleksunes18
- Julia Yue Cui16
- Xingguo Cheng16
- Monice Fiume15
- Nathan J. Cherrington14
- Angela L. Slitt13
- Supratim Choudhuri13
- Youcai Zhang13
- Jonathan Maher12
- Hong Lü9
- Kai Wu9
- Yaping Liu9
- Lillian J. Gill8
- Yuan‐Fu Lu8
All papers
- Mechanism of tissue-specific farnesoid X receptor in suppressing the expression of genes in bile-acid synthesis in mice
Authors: Bo Kong, Li Wang, John Y.L. Chiang, Youcai Zhang, Curtis D. Klaassen, Grace L. Guo - Hepatology 2012 cited by 444
- Beneficial Role of Nrf2 in Regulating NADPH Generation and Consumption
Authors: Kai Wu, Julia Yue Cui, Curtis D. Klaassen - Toxicological Sciences 2011 cited by 364
- Xenobiotic, Bile Acid, and Cholesterol Transporters: Function and Regulation
Authors: Curtis D. Klaassen, Lauren M. Aleksunes - Pharmacological Reviews 2010 cited by 797
- Metallothionein protection of cadmium toxicity
Authors: Curtis D. Klaassen, Jie Liu, Bhalchandra A. Diwan - Toxicology and Applied Pharmacology 2009 cited by 728
- Effect of various antibiotics on modulation of intestinal microbiota and bile acid profile in mice
Authors: Youcai Zhang, Pallavi B. Limaye, Helen J. Renaud, Curtis D. Klaassen - Toxicology and Applied Pharmacology 2014 cited by 159
- Review: Mechanisms of How the Intestinal Microbiota Alters the Effects of Drugs and Bile Acids
Authors: Curtis D. Klaassen, Julia Yue Cui - Drug Metabolism and Disposition 2015 cited by 199
- Molecular Regulation of Bile Acid Homeostasis
Authors: Supratim Choudhuri, Curtis D. Klaassen - Drug Metabolism and Disposition 2021 cited by 68
- NF-E2-Related Factor 2 Inhibits Lipid Accumulation and Oxidative Stress in Mice Fed a High-Fat Diet
Authors: Yuji Tanaka, Lauren M. Aleksunes, Ronnie L. Yeager, Maxwell A. Gyamfi, Noriko Esterly, Grace L. Guo, Curtis D. Klaassen - Journal of Pharmacology and Experimental Therapeutics 2008 cited by 255
- Suppressed farnesoid X receptor by iron overload in mice and humans potentiates iron‐induced hepatotoxicity
Authors: Hui Xiong, Chunze Zhang, Lifeng Han, Tong Xu, Khawar Saeed, Jing Han, Jing Liu, Curtis D. Klaassen, Frank J. Gonzalez, Yuan‐Fu Lu, Youcai Zhang - Hepatology 2021 cited by 38
- Glucose and Insulin Induction of Bile Acid Synthesis
Authors: Tiangang Li, Jessica M. Francl, Shannon Boehme, Adrian Ochoa, Youcai Zhang, Curtis D. Klaassen, Sandra K. Erickson, John Y.L. Chiang - Journal of Biological Chemistry 2011 cited by 214
- Effect of bile duct ligation on bile acid composition in mouse serum and liver
Authors: Youcai Zhang, Ji‐Young Hong, Cheryl E. Rockwell, Bryan L. Copple, Hartmut Jaeschke, Curtis D. Klaassen - Liver International 2011 cited by 215
- Impaired Generation of 12-Hydroxylated Bile Acids Links Hepatic Insulin Signaling with Dyslipidemia
Authors: Rebecca A. Haeusler, Matthew Pratt–Hyatt, Carrie L. Welch, Curtis D. Klaassen, Domenico Accili - Cell Metabolism 2011 cited by 152
- Structure, Function, Expression, Genomic Organization, and Single Nucleotide Polymorphisms of Human ABCB1 (MDR1), ABCC (MRP), and ABCG2 (BCRP) Efflux Transporters
Authors: Supratim Choudhuri, Curtis D. Klaassen - International Journal of Toxicology 2006 cited by 413
- Repeated administration of berberine inhibits cytochromes P450 in humans
Authors: Ying Guo, Yao Chen, Zhi‐Rong Tan, Curtis D. Klaassen, Hong‐Hao Zhou - European Journal of Clinical Pharmacology 2011 cited by 117
- Quantitative-profiling of bile acids and their conjugates in mouse liver, bile, plasma, and urine using LC–MS/MS
Authors: Yazen Alnouti, Iván L. Csanaky, Curtis D. Klaassen - Journal of Chromatography B 2008 cited by 256
- Role of Nrf2 in preventing ethanol-induced oxidative stress and lipid accumulation
Authors: Kai Wu, Jie Liu, Curtis D. Klaassen - Toxicology and Applied Pharmacology 2012 cited by 147
- Effect of Graded Nrf2 Activation on Phase-I and -II Drug Metabolizing Enzymes and Transporters in Mouse Liver
Authors: Kai Wu, Julia Yue Cui, Curtis D. Klaassen - PLoS ONE 2012 cited by 144
- Safety Assessment of Propylene Glycol, Tripropylene Glycol, and PPGs as Used in Cosmetics
Authors: Monice Fiume, Wilma F. Bergfeld, D. Belsito, Ronald A. Hill, Curtis D. Klaassen, D.C. Liebler, James G. Marks, Ronald C. Shank, Thomas J. Slaga, Paul W. Snyder, F. Alan Andersen - International Journal of Toxicology 2012 cited by 126
- Compensatory Induction of Liver Efflux Transporters in Response to ANIT-Induced Liver Injury Is Impaired in FXR-Null Mice
Authors: Yue Cui, Lauren M. Aleksunes, Yuji Tanaka, Michael Goedken, Curtis D. Klaassen - Toxicological Sciences 2009 cited by 126
- Oleanolic acid reprograms the liver to protect against hepatotoxicants, but is hepatotoxic at high doses
Authors: Jie Liu, Yuan‐Fu Lu, Qin Wu, Shangfu Xu, Fuguo Shi, Curtis D. Klaassen - Liver International 2018 cited by 79
- Final Report of the Safety Assessment of Kojic Acid as Used in Cosmetics
Authors: Christina L. Burnett, Wilma F. Bergfeld, D. Belsito, Ronald A. Hill, Curtis D. Klaassen, D.C. Liebler, James G. Marks, Ronald C. Shank, Thomas J. Slaga, Paul W. Snyder, F. Alan Andersen - International Journal of Toxicology 2010 cited by 182
- Transcriptional Regulation of Renal Cytoprotective Genes by Nrf2 and Its Potential Use as a Therapeutic Target to Mitigate Cisplatin-Induced Nephrotoxicity
Authors: Lauren M. Aleksunes, Michael Goedken, Cheryl E. Rockwell, Jüergen Thomale, José E. Manautou, Curtis D. Klaassen - Journal of Pharmacology and Experimental Therapeutics 2010 cited by 173
- Increased Nrf2 Activation in Livers from Keap1-Knockdown Mice Increases Expression of Cytoprotective Genes that Detoxify Electrophiles more than those that Detoxify Reactive Oxygen Species
Authors: Scott A. Reisman, Ronnie L. Yeager, Masayuki Yamamoto, Curtis D. Klaassen - Toxicological Sciences 2009 cited by 170
- RNA-Seq Quantification of Hepatic Drug Processing Genes in Germ-Free Mice
Authors: Felcy Pavithra Selwyn, Julia Yue Cui, Curtis D. Klaassen - Drug Metabolism and Disposition 2015 cited by 118
