David Cortez
Active 1995–2024
- 84
- Papers
- 21,913
- Citations
- 68
- h-index
- 83
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology74%
- Medicine22%
- Immunology and Microbiology1.5%
- Agricultural and Biological Sciences0.9%
- Neuroscience0.6%
- Environmental Science0.4%
- Other0.6%
Topics
- DNA Repair Mechanisms20.9%
- CRISPR and Genetic Engineering5.7%
- Cancer-related Molecular Pathways5.6%
- PARP inhibition in cancer therapy5.3%
- Microtubule and mitosis dynamics4.2%
- Genomics and Chromatin Dynamics3.7%
- Other54.6%
Coauthors
- Gloria G. Glick11
- Runxiang Zhao10
- Stephen J. Elledge9
- Bianca M. Sirbu7
- Brandt F. Eichman7
- Courtney A. Lovejoy7
- Huzefa Dungrawala7
- Kavi P.M. Mehta7
- Walter Chazin7
- Ann Marie Pendergast6
- Jessica W. Luzwick6
- Kareem N. Mohni6
- Frank B. Couch5
- Karlene A. Cimprich5
- Archana Krishnamoorthy4
- Carol E. Bansbach4
- Daniel A. Mordes4
- Jun Qin4
- Kamakoti P. Bhat4
- Madison B. Adolph4
- Petria S. Thompson4
- Rémy Betous4
- Sarah R. Wessel4
- Scott W. Hiebert4
All papers
- Replication fork stability confers chemoresistance in BRCA-deficient cells
Authors: Arnab Ray Chaudhuri, Elsa Callén, Xia Ding, Ewa Gogola, Alexandra A. Duarte, Ji‐Eun Lee, Nancy Wong, Vanesa Lafarga, Jennifer A. Calvo, Nicholas J. Panzarino, Sam John, Amanda Day, Anna Vidal Crespo, Binghui Shen, Linda M. Starnes, Julian R. de Ruiter, J. Daniel, Panagiotis A. Konstantinopoulos, David Cortez, Sharon B. Cantor, Óscar Fernández-Capetillo, Kai Ge, Jos Jonkers, Sven Rottenberg, Shyam K. Sharan, André Nussenzweig - Nature 2016 cited by 949
- The essential kinase ATR: ensuring faithful duplication of a challenging genome
Authors: Joshua C. Saldivar, David Cortez, Karlene A. Cimprich - Nature Reviews Molecular Cell Biology 2017 cited by 844
- The plasticity of DNA replication forks in response to clinically relevant genotoxic stress
Authors: Matteo Berti, David Cortez, Massimo Lopes - Nature Reviews Molecular Cell Biology 2020 cited by 348
- ATR: an essential regulator of genome integrity
Authors: Karlene A. Cimprich, David Cortez - Nature Reviews Molecular Cell Biology 2008 cited by 1,780
- RPA and RAD51: fork reversal, fork protection, and genome stability
Authors: Kamakoti P. Bhat, David Cortez - Nature Structural & Molecular Biology 2018 cited by 356
- Chk1 is an essential kinase that is regulated by Atr and required for the G2/M DNA damage checkpoint
Authors: Qinghua Liu, Saritha Guntuku, Xian-Shu Cui, Shuhei Matsuoka, David Cortez, Katsuyuki Tamai, Guangbin Luo, Sandra Carattini-Rivera, Francesco J. DeMayo, Allan Bradley, L A Donehower, Stephen J. Elledge - Genes & Development 2000 cited by 1,619
- An intrinsic S/G 2 checkpoint enforced by ATR
Authors: Joshua C. Saldivar, Stephan Hamperl, M Bocek, Mingyu Chung, Thomas E. Bass, Fernanda Cisneros-Soberanis, Kumiko Samejima, Linfeng Xie, James R. Paulson, William C. Earnshaw, David Cortez, Tobias Meyer, Karlene A. Cimprich - Science 2018 cited by 311
- HMCES Maintains Genome Integrity by Shielding Abasic Sites in Single-Strand DNA
Authors: Kareem N. Mohni, Sarah R. Wessel, Runxiang Zhao, Andrea C. Wojciechowski, Jessica W. Luzwick, Hillary M. Layden, Brandt F. Eichman, Petria S. Thompson, Kavi P.M. Mehta, David Cortez - Cell 2018 cited by 194
- The Replication Checkpoint Prevents Two Types of Fork Collapse without Regulating Replisome Stability
Authors: Huzefa Dungrawala, Kristie L. Rose, Kamakoti P. Bhat, Kareem N. Mohni, Gloria G. Glick, Frank B. Couch, David Cortez - Molecular Cell 2015 cited by 379
- Replication-Coupled DNA Repair
Authors: David Cortez - Molecular Cell 2019 cited by 250
- ATR and ATRIP: Partners in Checkpoint Signaling
Authors: David Cortez, Saritha Guntuku, Jun Qin, Stephen J. Elledge - Science 2001 cited by 977
- Replication Fork Slowing and Reversal upon DNA Damage Require PCNA Polyubiquitination and ZRANB3 DNA Translocase Activity
Authors: Marko Vujanovic, Jana Krietsch, Maria Chiara Raso, Nastassja Terraneo, Ralph Zellweger, Jonas Schmid, Angelo Taglialatela, Jen‐Wei Huang, Cory Holland, Katharina Zwicky, Raquel Herrador, Heinz Jacobs, David Cortez, Alberto Ciccia, Lorenza Penengo, Massimo Lopes - Molecular Cell 2017 cited by 239
- New insights into abasic site repair and tolerance
Authors: Petria S. Thompson, David Cortez - DNA repair 2020 cited by 168
- RAD51 bypasses the CMG helicase to promote replication fork reversal
Authors: Wenpeng Liu, Yuichiro Saito, Jessica Jackson, Rahul Bhowmick, Masato T. Kanemaki, Alessandro Vindigni, David Cortez - Science 2023 cited by 104
- ATR phosphorylates SMARCAL1 to prevent replication fork collapse
Authors: Frank B. Couch, Carol E. Bansbach, Robert Driscoll, Jessica W. Luzwick, Gloria G. Glick, Rémy Betous, Clinton Carroll, Sung Yun Jung, Jun Qin, Karlene A. Cimprich, David Cortez - Genes & Development 2013 cited by 406
- Identification of Proteins at Active, Stalled, and Collapsed Replication Forks Using Isolation of Proteins on Nascent DNA (iPOND) Coupled with Mass Spectrometry
Authors: Bianca M. Sirbu, W. Hayes McDonald, Huzefa Dungrawala, Akosua Badu-Nkansah, Gina M. Kavanaugh, Yaoyi Chen, David L. Tabb, David Cortez - Journal of Biological Chemistry 2013 cited by 258
- Analysis of protein dynamics at active, stalled, and collapsed replication forks
Authors: Bianca M. Sirbu, Frank B. Couch, Jordan T. Feigerle, Srividya Bhaskara, Scott W. Hiebert, David Cortez - Genes & Development 2011 cited by 441
- SMARCAL1 catalyzes fork regression and Holliday junction migration to maintain genome stability during DNA replication
Authors: Rémy Betous, Aaron C. Mason, Robert P. Rambo, Carol E. Bansbach, Akosua Badu-Nkansah, Bianca M. Sirbu, Brandt F. Eichman, David Cortez - Genes & Development 2012 cited by 292
- RADX Promotes Genome Stability and Modulates Chemosensitivity by Regulating RAD51 at Replication Forks
Authors: Huzefa Dungrawala, Kamakoti P. Bhat, Rémy Le Meur, Walter Chazin, Xia Ding, Shyam K. Sharan, Sarah R. Wessel, Aditya A. Sathe, Runxiang Zhao, David Cortez - Molecular Cell 2017 cited by 205
- Monitoring the spatiotemporal dynamics of proteins at replication forks and in assembled chromatin using isolation of proteins on nascent DNA
Authors: Bianca M. Sirbu, Frank B. Couch, David Cortez - Nature Protocols 2012 cited by 213
- Functional Analysis of the Replication Fork Proteome Identifies BET Proteins as PCNA Regulators
Authors: Sarah R. Wessel, Kareem N. Mohni, Jessica W. Luzwick, Huzefa Dungrawala, David Cortez - Cell Reports 2019 cited by 128
- Two replication fork remodeling pathways generate nuclease substrates for distinct fork protection factors
Authors: Wenpeng Liu, Archana Krishnamoorthy, Runxiang Zhao, David Cortez - Science Advances 2020 cited by 100
- CHK1 phosphorylates PRIMPOL to promote replication stress tolerance
Authors: Kavi P.M. Mehta, Vaughn Thada, Runxiang Zhao, Archana Krishnamoorthy, Micheal Leser, Kristie L. Rose, David Cortez - Science Advances 2022 cited by 55
- Deletion of Histone Deacetylase 3 Reveals Critical Roles in S Phase Progression and DNA Damage Control
Authors: Srividya Bhaskara, Brenda Chyla, Joseph M. Amann, Sarah K. Knutson, David Cortez, Zu-Wen Sun, Scott W. Hiebert - Molecular Cell 2008 cited by 382
