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David D. Schlaepfer

Active 1987–2025

92
Papers
26,951
Citations
79
h-index
90
i10-index

Citations

Citations per year for David D. Schlaepfer1959: 1 citations1979: 1 citations1981: 2 citations1987: 5 citations1988: 32 citations1989: 30 citations1990: 39 citations1991: 33 citations1992: 32 citations1993: 30 citations1994: 24 citations1995: 63 citations1996: 101 citations1997: 109 citations1998: 152 citations1999: 232 citations2000: 273 citations2001: 346 citations2002: 348 citations2003: 384 citations2004: 401 citations2005: 353 citations2006: 349 citations2007: 263 citations2008: 306 citations2009: 381 citations2010: 336 citations2011: 296 citations2012: 251 citations2013: 201 citations2014: 283 citations2015: 166 citations2016: 189 citations2017: 233 citations2018: 151 citations2019: 681 citations2020: 663 citations2021: 657 citations2022: 510 citations2023: 376 citations2024: 604 citations2025: 248 citations2026: 7 citations1960–1978: no citations, so these years are not shown1980: no citations, so this year is not shown1982–1986: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 3,118 citing papers, 36.2% of this breakdownChina: 1,002 citing papers, 11.6% of this breakdownUnited Kingdom: 570 citing papers, 6.6% of this breakdownGermany: 478 citing papers, 5.5% of this breakdownJapan: 342 citing papers, 4% of this breakdownItaly: 295 citing papers, 3.4% of this breakdownFrance: 291 citing papers, 3.4% of this breakdownCanada: 283 citing papers, 3.3% of this breakdownSpain: 165 citing papers, 1.9% of this breakdownSouth Korea: 161 citing papers, 1.9% of this breakdownNetherlands: 161 citing papers, 1.9% of this breakdownAustralia: 155 citing papers, 1.8% of this breakdown
0%36.2%Other 18.5%

Institutions

Fields

  • Medicine45.3%
  • Biochemistry, Genetics and Molecular Biology43.7%
  • Immunology and Microbiology3.6%
  • Neuroscience3%
  • Engineering1.6%
  • Materials Science0.8%
  • Other2%

Topics

  • Cell Adhesion Molecules Research12.3%
  • Cellular Mechanics and Interactions9.2%
  • Cancer Cells and Metastasis2.6%
  • Protein Kinase Regulation and GTPase Signaling2.3%
  • Protease and Inhibitor Mechanisms2.1%
  • Angiogenesis and VEGF in Cancer2.1%
  • Other69.4%

Coauthors

All papers

Open in search
  1. Targeting FAK in anticancer combination therapies

    Authors: John C. Dawson, Alan Serrels, Dwayne G. Stupack, David D. Schlaepfer, Margaret C. Frame - Nature reviews. Cancer 2021 cited by 391

  2. FAK in cancer: mechanistic findings and clinical applications

    Authors: Florian J. Sulzmaier, Christine Jean, David D. Schlaepfer - Nature reviews. Cancer 2014 cited by 1,394

  3. Integrin-regulated FAK–Src signaling in normal and cancer cells

    Authors: Satyajit K. Mitra, David D. Schlaepfer - Current Opinion in Cell Biology 2006 cited by 1,583

  4. Focal adhesion kinase: in command and control of cell motility

    Authors: Satyajit K. Mitra, Daniel Hanson, David D. Schlaepfer - Nature Reviews Molecular Cell Biology 2005 cited by 2,547

  5. Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression

    Authors: Hanane Laklai, Yekaterina A. Miroshnikova, Michael W. Pickup, Eric A. Collisson, Grace Kim, Alex Barrett, Ryan C. Hill, Johnathon N. Lakins, David D. Schlaepfer, Janna K. Mouw, Valerie S. LeBleu, Nilotpal Roy, Sergey V. Novitskiy, Julia S. Johansen, Valeria Poli, Raghu Kalluri, Christine A. Iacobuzio–Donahue, Laura D. Wood, Matthias Hebrok, Kirk C. Hansen, Harold L. Moses, Valerie M. Weaver - Nature Medicine 2016 cited by 601

  6. A Platform of Synthetic Lethal Gene Interaction Networks Reveals that the GNAQ Uveal Melanoma Oncogene Controls the Hippo Pathway through FAK

    Authors: Xiaodong Feng, Nadia Arang, Damiano Cosimo Rigiracciolo, Joo Sang Lee, Huwate Yeerna, Zhiyong Wang, Simone Lubrano, Ayush Kishore, Jonathan A. Pachter, Gabriele M. König, Marcello Maggiolini, Evi Kostenis, David D. Schlaepfer, Pablo Tamayo, Qianming Chen, Eytan Ruppin, J. Silvio Gutkind - Cancer Cell 2019 cited by 243

  7. Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation

    Authors: Ana M. Pasapera, I Schneider, Erin Rericha, David D. Schlaepfer, Clare M. Waterman - The Journal of Cell Biology 2010 cited by 577

  8. Tumor FAK orchestrates immunosuppression in ovarian cancer via the CD155/TIGIT axis

    Authors: Duygu Ozmadenci, Jayanth S. Shankara Narayanan, Jacob R. Andrew, Marjaana Ojalill, A. Barrie, Shulin Jiang, Samhita Iyer, Xiao Lei Chen, Michael Rose, Valeria Estrada, Alfredo Molinolo, Thomas Bertotto, Zbigniew Mikulski, Michael C. McHale, Rebekah R. White, Denise C. Connolly, Jonathan A. Pachter, Vijay K. Kuchroo, Dwayne G. Stupack, David D. Schlaepfer - National Academy of Sciences, Proceedings of the National Academy of Sciences 2022 cited by 75

  9. Nuclear FAK Promotes Cell Proliferation and Survival through FERM-Enhanced p53 Degradation

    Authors: Ssang‐Taek Lim, Xiao Lei Chen, Yangmi Lim, Dan Hanson, Thanh‐Trang Vo, Kyle Howerton, Nicholas Larocque, Susan J. Fisher, David D. Schlaepfer, Duško Ilić - Molecular Cell 2008 cited by 474

  10. FAK activity in cancer‐associated fibroblasts is a prognostic marker and a druggable key metastatic player in pancreatic cancer

    Authors: Sonia Zaghdoudi, Emilie Decaup, Ismahane Belhabib, Rémi Samain, Stéphanie Cassant‐Sourdy, Julia Rochotte, Alexia Brunel, David D. Schlaepfer, Jérôme Cros, Cindy Neuzillet, Manon Strehaïano, Amandine Alard, Richard Tomasini, Vinothini Rajeeve, Aurélie Perraud, Muriel Mathonnet, Oliver M.T. Pearce, Yvan Martineau, Stéphane Pyronnet, Corinne Bousquet, Christine Jean - EMBO Molecular Medicine 2020 cited by 105

  11. Force-FAK signaling coupling at individual focal adhesions coordinates mechanosensing and microtissue repair

    Authors: Dennis W. Zhou, Marc Fernández, Elijah N. Holland, Andrés F. García, Nicolas Castro, Eric B. O’Neill, Jeroen Eyckmans, Christopher S. Chen, Jianping Fu, David D. Schlaepfer, Andrés J. Garcı́a - Nature Communications 2021 cited by 84

  12. FAK integrates growth-factor and integrin signals to promote cell migration

    Authors: David J. Sieg, Christof R. Hauck, Duško Ilić, Candice K. Klingbeil, Erik Schaefer, Caroline H. Damsky, David D. Schlaepfer - Nature Cell Biology 2000 cited by 1,239

  13. Inhibition of endothelial FAK activity prevents tumor metastasis by enhancing barrier function

    Authors: Christine Jean, Xiao Lei Chen, Ju‐Ock Nam, Isabelle Tancioni, Sean Uryu, Christine Lawson, Kristy Ward, Colin Walsh, Nichol Miller, Majid Ghassemian, Patric Turowski, Elisabetta Dejana, Sara M. Weis, David A. Cheresh, David D. Schlaepfer - The Journal of Cell Biology 2014 cited by 172

  14. Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

    Authors: David D. Schlaepfer, Steven K. Hanks, Tony Hunter, Peter van der Geer - Nature 1994 cited by 1,610

  15. VEGF-Induced Vascular Permeability Is Mediated by FAK

    Authors: Xiao Lei Chen, Ju‐Ock Nam, Christine Jean, Christine Lawson, Colin Walsh, Erik T. Goka, Ssang‐Taek Lim, Alok Tomar, Isabelle Tancioni, Sean Uryu, Jun‐Lin Guan, Lisette M. Acevedo, Sara M. Weis, David A. Cheresh, David D. Schlaepfer - Developmental Cell 2012 cited by 338

  16. FAK Activation Promotes SMC Dedifferentiation via Increased DNA Methylation in Contractile Genes

    Authors: Kyuho Jeong, James M. Murphy, Jung-Hyun Kim, Pamela Moore Campbell, Hyeonsoo Park, Yelitza A.R. Rodriguez, Chung-Sik Choi, Jun-Sub Kim, Sangwon Park, Hyun Joon Kim, Jonathan G. Scammell, David S. Weber, Richard E. Honkanen, David D. Schlaepfer, Eun-Young Erin Ahn, Ssang-Taek Steve Lim - Circulation Research 2021 cited by 42

  17. PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments

    Authors: Isabelle Tanjoni, Colin Walsh, Sean Uryu, Alok Tomar, Ju‐Ock Nam, Ainhoa Mielgo, Ssang‐Taek Lim, Congxin Liang, Marcel Koenig, Neela Patel, Cheni Kwok, Gerald McMahon, Dwayne G. Stupack, David D. Schlaepfer - Cancer Biology & Therapy 2010 cited by 162

  18. Nuclear Focal Adhesion Kinase Controls Vascular Smooth Muscle Cell Proliferation and Neointimal Hyperplasia Through GATA4-Mediated Cyclin D1 Transcription

    Authors: Kyuho Jeong, Jung‐Hyun Kim, James M. Murphy, Hyeon‐Soo Park, Su-Jeong Kim, Yelitza A. R. Rodriguez, Hyunkyung Kong, Chung‐Sik Choi, Jun‐Lin Guan, Joan M. Taylor, Thomas Lincoln, William T. Gerthoffer, Jun‐Sub Kim, E. Ahn, David D. Schlaepfer, Ssang‐Taek Lim, David D. Schlaepfer, Ssang‐Taek Lim - Circulation Research 2019 cited by 135

  19. Differential regulation of cell motility and invasion by FAK

    Authors: Datsun A. Hsia, Satyajit K. Mitra, Christof R. Hauck, Daniel N. Streblow, Jay A. Nelson, Duško Ilić, Shuang Huang, Erguang Li, Glen R. Nemerow, Jay Leng, Kathryn Spencer, David A. Cheresh, David D. Schlaepfer - The Journal of Cell Biology 2003 cited by 530

  20. FAK/PYK2 promotes the Wnt/β-catenin pathway and intestinal tumorigenesis by phosphorylating GSK3β

    Authors: Chenxi Gao, Guangming Chen, Shih–Fan Kuan, Dennis Han Zhang, David D. Schlaepfer, Jing Hu - eLife 2015 cited by 120

  21. Inhibition of focal adhesion kinase (FAK) activity prevents anchorage-independent ovarian carcinoma cell growth and tumor progression

    Authors: Kristy Ward, Isabelle Tancioni, Christine Lawson, Nichol Miller, Christine Jean, Xiao Lei Chen, Sean Uryu, Josephine Kim, David G. Jackson, Dwayne G. Stupack, Steven C. Plaxe, David D. Schlaepfer - Clinical & Experimental Metastasis 2012 cited by 111

  22. FAK, vinculin, and talin control mechanosensitive YAP nuclear localization

    Authors: Elijah N. Holland, Marc Fernández, Dennis W. Zhou, Eric B. O’Neill, Ayanna U. Woodfolk, Ana Mora‐Boza, Jianping Fu, David D. Schlaepfer, Andrés J. Garcı́a - Biomaterials 2024 cited by 51

  23. Signaling through focal adhesion kinase

    Authors: David D. Schlaepfer, Christof R. Hauck, David J. Sieg - Progress in Biophysics and Molecular Biology 1999 cited by 1,171

  24. Focal adhesion kinase: switching between GAPs and GEFs in the regulation of cell motility

    Authors: Alok Tomar, David D. Schlaepfer - Current Opinion in Cell Biology 2009 cited by 234