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David J. Lefer

Active 1986–2025

145
Papers
28,187
Citations
93
h-index
138
i10-index

Citations

Citations per year for David J. Lefer1985: 1 citations1986: 4 citations1987: 1 citations1988: 5 citations1991: 1 citations1992: 6 citations1993: 29 citations1994: 58 citations1995: 89 citations1996: 88 citations1997: 94 citations1998: 94 citations1999: 128 citations2000: 154 citations2001: 174 citations2002: 239 citations2003: 211 citations2004: 242 citations2005: 198 citations2006: 170 citations2007: 192 citations2008: 229 citations2009: 279 citations2010: 295 citations2011: 302 citations2012: 350 citations2013: 335 citations2014: 342 citations2015: 343 citations2016: 297 citations2017: 289 citations2018: 301 citations2019: 788 citations2020: 916 citations2021: 823 citations2022: 670 citations2023: 440 citations2024: 629 citations2025: 297 citations2026: 4 citations1989–1990: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 2,910 citing papers, 29.6% of this breakdownChina: 1,533 citing papers, 15.6% of this breakdownUnited Kingdom: 570 citing papers, 5.8% of this breakdownGermany: 543 citing papers, 5.5% of this breakdownItaly: 426 citing papers, 4.3% of this breakdownJapan: 386 citing papers, 3.9% of this breakdownCanada: 285 citing papers, 2.9% of this breakdownFrance: 198 citing papers, 2% of this breakdownAustralia: 194 citing papers, 2% of this breakdownNetherlands: 186 citing papers, 1.9% of this breakdownSpain: 177 citing papers, 1.8% of this breakdownIndia: 158 citing papers, 1.6% of this breakdown
0%29.6%Other 23.1%

Institutions

Fields

  • Medicine48.6%
  • Biochemistry, Genetics and Molecular Biology40.5%
  • Immunology and Microbiology2.7%
  • Neuroscience1.9%
  • Engineering1.2%
  • Agricultural and Biological Sciences1.2%
  • Other3.9%

Topics

  • Sulfur Compounds in Biology7.3%
  • Nitric Oxide and Endothelin Effects4.9%
  • Cardiac Ischemia and Reperfusion4.3%
  • Cardiac Fibrosis and Remodeling2.1%
  • Eicosanoids and Hypertension Pharmacology1.8%
  • Molecular Sensors and Ion Detection1.6%
  • Other78%

Coauthors

All papers

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  1. Hydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial function

    Authors: John W. Elrod, John W. Calvert, Jo Morrison, Jeannette E. Doeller, David W. Kraus, Ling Tao, Xiangying Jiao, Rosario Scalia, Levente Kiss, Csaba Szabó, Hideo Kimura, Chi-Wing Chow, David J. Lefer - National Academy of Sciences, Proceedings of the National Academy of Sciences 2007 cited by 1,252

  2. Choline Diet and Its Gut Microbe–Derived Metabolite, Trimethylamine N-Oxide, Exacerbate Pressure Overload–Induced Heart Failure

    Authors: Chelsea L. Organ, Hiroyuki Otsuka, Shashi Bhushan, Zeneng Wang, Jessica Bradley, Rishi Trivedi, David J. Polhemus, W.H. Wilson Tang, Yuping Wu, Stanley L. Hazen, David J. Lefer - Circulation Heart Failure 2015 cited by 384

  3. Guidelines for experimental models of myocardial ischemia and infarction

    Authors: Merry L. Lindsey, Roberto Bolli, John M. Canty, Xiao‐Jun Du, Nikolaos G. Frangogiannis, Stefan Frantz, Robert G. Gourdie, Jeffrey W. Holmes, Steven P. Jones, Robert A. Kloner, David J. Lefer, Ronglih Liao, Elizabeth Murphy, Peipei Ping, Karin Przyklenk, Fabio A. Recchia, Lisa Schwartz Longacre, Crystal M. Ripplinger, Jennifer E. Van Eyk, Gerd Heusch - American Journal of Physiology-Heart and Circulatory Physiology 2018 cited by 511

  4. Hydrogen Sulfide Mediates Cardioprotection Through Nrf2 Signaling

    Authors: John W. Calvert, Saurabh Kumar Jha, Susheel Gundewar, John W. Elrod, Arun Ramachandran, Christopher B. Pattillo, Christopher G. Kevil, David J. Lefer - Circulation Research 2009 cited by 719

  5. pH-Controlled Hydrogen Sulfide Release for Myocardial Ischemia-Reperfusion Injury

    Authors: Jianming Kang, Zhen Li, Chelsea L. Organ, Chung‐Min Park, Chuntao Yang, Armando Pacheco, Difei Wang, David J. Lefer, Ming Xian - Journal of the American Chemical Society 2016 cited by 268

  6. Nonlethal Inhibition of Gut Microbial Trimethylamine N‐oxide Production Improves Cardiac Function and Remodeling in a Murine Model of Heart Failure

    Authors: Chelsea L. Organ, Zhen Li, Thomas E. Sharp, David J. Polhemus, Nilaksh Gupta, Traci Goodchild, W.H. Wilson Tang, Stanley L. Hazen, David J. Lefer - Journal of the American Heart Association 2020 cited by 123

  7. Exercise Training Promotes Cardiac Hydrogen Sulfide Biosynthesis and Mitigates Pyroptosis to Prevent High-Fat Diet-Induced Diabetic Cardiomyopathy

    Authors: Sumit Kar, Hamid R. Shahshahan, Bryan T. Hackfort, Santosh K. Yadav, Roopali Yadav, Tyler N. Kambis, David J. Lefer, Paras K. Mishra - Antioxidants 2019 cited by 85

  8. Mitochondrial H 2 S Regulates BCAA Catabolism in Heart Failure

    Authors: Zhen Li, Huijing Xia, Thomas E. Sharp, Kyle B. LaPenna, John W. Elrod, Kevin M. Casin, Ken Liu, John W. Calvert, Vinh Q. Chau, Fadi N. Salloum, Shi Xu, Ming Xian, Noriyuki Nagahara, Traci Goodchild, David J. Lefer - Circulation Research 2022 cited by 61

  9. Emergence of Hydrogen Sulfide as an Endogenous Gaseous Signaling Molecule in Cardiovascular Disease

    Authors: David J. Polhemus, David J. Lefer - Circulation Research 2014 cited by 439

  10. Activation of AMP-Activated Protein Kinase by Metformin Improves Left Ventricular Function and Survival in Heart Failure

    Authors: Susheel Gundewar, John W. Calvert, Saurabh Kumar Jha, Iris Toedt‐Pingel, Sang Yong Ji, Denise Nunez, Arun Ramachandran, Mauricio Anaya-Cisneros, Rong Tian, David J. Lefer - Circulation Research 2008 cited by 416

  11. A Fluorescent Probe for Fast and Quantitative Detection of Hydrogen Sulfide in Blood

    Authors: Hanjing Peng, Yunfeng Cheng, Chaofeng Dai, Adrienne L. King, Benjamin L. Predmore, David J. Lefer, Binghe Wang - Angewandte Chemie 2011 cited by 638

  12. Hydrogen sulfide cytoprotective signaling is endothelial nitric oxide synthase-nitric oxide dependent

    Authors: Adrienne L. King, David J. Polhemus, Shashi Bhushan, Hiroyuki Otsuka, Kazuhisa Kondo, Chad K. Nicholson, Jessica Bradley, Kazi N. Islam, John W. Calvert, Ya‐Xiong Tao, Tammy R. Dugas, Eric E. Kelley, John W. Elrod, Paul L. Huang, Rui Wang, David J. Lefer - National Academy of Sciences, Proceedings of the National Academy of Sciences 2014 cited by 364

  13. H 2 S Protects Against Pressure Overload–Induced Heart Failure via Upregulation of Endothelial Nitric Oxide Synthase

    Authors: Kazuhisa Kondo, Shashi Bhushan, Adrienne L. King, Sumanth D. Prabhu, Tariq Hamid, Steven C. Koenig, Toyoaki Murohara, Benjamin L. Predmore, Gabriel Gojon, Gabriel Gojon, Rui Wang, Naveena Karusula, Chad K. Nicholson, John W. Calvert, David J. Lefer - Circulation 2013 cited by 350

  14. Hydrogen Sulfide Modulates Endothelial–Mesenchymal Transition in Heart Failure

    Authors: Zhen Li, Huijing Xia, Thomas E. Sharp, Kyle B. LaPenna, Antonia Katsouda, John W. Elrod, Josef Pfeilschifter, Karl‐Friedrich Beck, Shi Xu, Ming Xian, Traci Goodchild, Andreas Papapetropoulos, David J. Lefer - Circulation Research 2022 cited by 43

  15. Hydrogen Sulfide in Biochemistry and Medicine

    Authors: Benjamin L. Predmore, David J. Lefer, Gabriel Gojon - Antioxidants and Redox Signaling 2012 cited by 392

  16. Genetic and Pharmacologic Hydrogen Sulfide Therapy Attenuates Ischemia-Induced Heart Failure in Mice

    Authors: John W. Calvert, Marah Elston, Chad K. Nicholson, Susheel Gundewar, Saurabh Kumar Jha, John W. Elrod, Arun Ramachandran, David J. Lefer - Circulation 2010 cited by 292

  17. 3-Mercaptopyruvate sulfurtransferase produces potential redox regulators cysteine- and glutathione-persulfide (Cys-SSH and GSSH) together with signaling molecules H2S2, H2S3 and H2S

    Authors: Yuka Kimura, Shin Koike, Norihiro Shibuya, David J. Lefer, Yuki Ogasawara, Hideo Kimura - Scientific Reports 2017 cited by 147

  18. Acute Metformin Therapy Confers Cardioprotection Against Myocardial Infarction Via AMPK-eNOS–Mediated Signaling

    Authors: John W. Calvert, Susheel Gundewar, Saurabh Kumar Jha, James J.M. Greer, William H. Bestermann, Rong Tian, David J. Lefer - Diabetes 2007 cited by 421

  19. Novel Insights Into Hydrogen Sulfide–Mediated Cytoprotection

    Authors: John W. Calvert, William A. Coetzee, David J. Lefer - Antioxidants and Redox Signaling 2009 cited by 312

  20. Renal Sympathetic Denervation Protects the Failing Heart Via Inhibition of Neprilysin Activity in the Kidney

    Authors: David J. Polhemus, Rishi Trivedi, Juan Gao, Zhen Li, Amy Scarborough, Traci Goodchild, Kurt J. Varner, Huijing Xia, Frank W. Smart, Daniel R. Kapusta, David J. Lefer - Journal of the American College of Cardiology 2017 cited by 94

  21. Protective Actions of H2S in Acute Myocardial Infarction and Heart Failure

    Authors: Erminia Donnarumma, Rishi Trivedi, David J. Lefer - Comprehensive physiology 2017 cited by 88

  22. The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals.

    Authors: Yasuko Kureishi, Zhengyu Luo, Ichiro Shiojima, Ann Bialik, David Fulton, David J. Lefer, William C. Sessa, Kenneth Walsh - Nature Medicine 2000 cited by 1,434

  23. Nitrate and nitrite in biology, nutrition and therapeutics

    Authors: Jon O. Lundberg, Mark T. Gladwin, Amrita Ahluwalia, Nigel Benjamin, Nathan S. Bryan, Anthony R. Butler, Pedro Cabrales, Angela Fago, Martin Feelisch, Peter C. Ford, Bruce Α. Freeman, Michael Frenneaux, Joel M. Friedman, Malte Kelm, Christopher G. Kevil, Daniel B. Kim‐Shapiro, Andrey V. Kozlov, Jack R. Lancaster, David J. Lefer, Kenneth E.L. McColl, Kenneth R. McCurry, Rakesh P. Patel, Joel Petersson, Tienush Rassaf, В. П. Реутов, George B. Richter‐Addo, Alan N. Schechter, Sruti Shiva, Koichiro Tsuchiya, Ernst E. van Faassen, David J. Webb, Brian S. Zuckerbraun, Jay L. Zweíer, Eddie Weitzberg - Nature Chemical Biology 2009 cited by 610

  24. Combination Sodium Nitrite and Hydralazine Therapy Attenuates Heart Failure With Preserved Ejection Fraction Severity in a “2‐Hit” Murine Model

    Authors: Kyle B. LaPenna, Zhen Li, Jake E. Doiron, Thomas E. Sharp, Huijing Xia, Karl Moles, Kashyap Koul, John S. Wang, David J. Polhemus, Traci Goodchild, Ravi B. Patel, Sanjiv J. Shah, David J. Lefer - Journal of the American Heart Association 2023 cited by 27