David J. Rawlings
Active 1980–2025
- 124
- Papers
- 19,943
- Citations
- 81
- h-index
- 118
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine39.1%
- Immunology and Microbiology29.1%
- Biochemistry, Genetics and Molecular Biology27.5%
- Chemistry1.7%
- Neuroscience1.2%
- Agricultural and Biological Sciences0.4%
- Other1%
Topics
- T-cell and B-cell Immunology8.5%
- Immune Cell Function and Interaction7.2%
- Immunodeficiency and Autoimmune Disorders3.4%
- Chronic Lymphocytic Leukemia Research3.2%
- Immunotherapy and Immune Responses2.8%
- CRISPR and Genetic Engineering2.6%
- Other72.3%
Coauthors
- Andrew M. Scharenberg16
- Jane H. Buckner15
- Owen N. Witte15
- Shaun W. Jackson12
- Iram Khan11
- Karen Sommer11
- R. Kato11
- Richard G. James11
- Socheath Khim11
- Christopher D. Thouvenel9
- Malika Hale9
- Almut Meyer‐Bahlburg8
- Marion Pepper8
- Swati Singh8
- Blythe Sather7
- Denny Liggitt7
- Eric J. Allenspach7
- Karen Cerosaletti7
- Xuezhi Dai7
- Yu Chen7
- Hans D. Ochs6
- Jason Netland6
- Matthew I. Wahl6
- Michael Gale6
All papers
- CD19+CD24hiCD38hi B Cells Exhibit Regulatory Capacity in Healthy Individuals but Are Functionally Impaired in Systemic Lupus Erythematosus Patients
Authors: Paul A. Blair, Lina Yassin Noreña, Fabian Flores‐Borja, David J. Rawlings, David Isenberg, Michael R. Ehrenstein, Claudia Mauri - Immunity 2010 cited by 1,533
- Altered B cell signalling in autoimmunity
Authors: David J. Rawlings, Genita Metzler, Michelle N. Wray-Dutra, Shaun W. Jackson - Nature reviews. Immunology 2017 cited by 301
- Pancreatic islet-specific engineered T regs exhibit robust antigen-specific and bystander immune suppression in type 1 diabetes models
Authors: Soo Jung Yang, Akhilesh K. Singh, Travis Drow, Tori Tappen, Yuchi Honaker, Fariba Barahmand-pour-Whitman, Peter S. Linsley, Karen Cerosaletti, Kelsey E. Mauk, Yufei Xiang, Jessica Smith, Emma Mortensen, Peter J. Cook, Karen Sommer, Iram Khan, Denny Liggitt, David J. Rawlings, Jane H. Buckner - Science Translational Medicine 2022 cited by 77
- B cell–derived IL-6 initiates spontaneous germinal center formation during systemic autoimmunity
Authors: Tanvi Arkatkar, Samuel W. Du, Holly M. Jacobs, Elizabeth M. Dam, Baidong Hou, Jane H. Buckner, David J. Rawlings, Shaun W. Jackson - The Journal of Experimental Medicine 2017 cited by 265
- Gene editing to induce FOXP3 expression in human CD4 + T cells leads to a stable regulatory phenotype and function
Authors: Yuchi Honaker, Nicholas Hubbard, Yufei Xiang, Logan Fisher, David Hagin, Karen Sommer, Yumei Song, Soo Jung Yang, Christina Lopez, Tori Tappen, Elizabeth M. Dam, Iram Khan, Malika Hale, Jane H. Buckner, Andrew M. Scharenberg, Troy R. Torgerson, David J. Rawlings - Science Translational Medicine 2020 cited by 117
- B cell IFN-γ receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6
Authors: Shaun W. Jackson, Holly M. Jacobs, Tanvi Arkatkar, Elizabeth M. Dam, Nicole E. Scharping, Nikita Kolhatkar, Baidong Hou, Jane H. Buckner, David J. Rawlings - The Journal of Experimental Medicine 2016 cited by 216
- Functional SARS-CoV-2-Specific Immune Memory Persists after Mild COVID-19
Authors: Lauren B. Rodda, Jason Netland, Laila Shehata, Kurt B. Pruner, Peter A. Morawski, Christopher D. Thouvenel, Kennidy K. Takehara, Julie Eggenberger, Emily A. Hemann, Hayley R. Waterman, Mitchell L. Fahning, Yu Chen, Malika Hale, Jennifer A. Rathe, Caleb Stokes, Samuel Wrenn, Brooke Fiala, Lauren Carter, Jessica A. Hamerman, Neil P. King, Michael Gale, Daniel Campbell, David J. Rawlings, Marion Pepper - Cell 2020 cited by 713
- NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22
Authors: Marianne R. Spalinger, Stephanie Kasper, Claudia Gottier, Silvia Lang, Kirstin Atrott, Stephan R. Vavricka, Sylvie Scharl, Petrus M. Gutte, Markus G. Grütter, Hans‐Dietmar Beer, Emmanuel Contassot, Andrew C. Chan, Xuezhi Dai, David J. Rawlings, Florian Mair, Burkhard Becher, Werner Falk, Michael Fried, Gerhard Rogler, Michael Scharl - Journal of Clinical Investigation 2016 cited by 230
- Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia
Authors: Satoshi Tsukada, Douglas C. Saffran, David J. Rawlings, Ornella Parolini, R.Cutler Allen, Ivana Klisak, Robert S. Sparkes, Hiromi Kubagawa, T. Mohandas, Shirley G. Quan, John W. Belmont, Max D. Cooper, Mary Ellen Conley, Owen N. Witte - Cell 1993 cited by 1,346
- Engineering Protein-Secreting Plasma Cells by Homology-Directed Repair in Primary Human B Cells
Authors: King L. Hung, Iana Meitlis, Malika Hale, Chun‐Yu Chen, Swati Singh, Shaun W. Jackson, Carol H. Miao, Iram Khan, David J. Rawlings, Richard G. James - Molecular Therapy 2017 cited by 148
- Integration of B cell responses through Toll-like receptors and antigen receptors
Authors: David J. Rawlings, Marc A. Schwartz, Shaun W. Jackson, Almut Meyer‐Bahlburg - Nature reviews. Immunology 2012 cited by 329
- Efficient modification of CCR5 in primary human hematopoietic cells using a megaTAL nuclease and AAV donor template
Authors: Blythe Sather, Guillermo S. Romano Ibarra, Karen Sommer, Gabrielle Curinga, Malika Hale, Iram Khan, Swati Singh, Yumei Song, Kamila Gwiazda, Jaya Sahni, Jordan Jarjour, Alexander Astrakhan, Thor A. Wagner, Andrew M. Scharenberg, David J. Rawlings - Science Translational Medicine 2015 cited by 229
- Engineering HIV-Resistant, Anti-HIV Chimeric Antigen Receptor T Cells
Authors: Malika Hale, Taylor D. Mesojednik, Guillermo S. Romano Ibarra, Jaya Sahni, Alison Bernard, Karen Sommer, Andrew M. Scharenberg, David J. Rawlings, Thor A. Wagner - Molecular Therapy 2017 cited by 166
- PTPN22 regulates NLRP3-mediated IL1B secretion in an autophagy-dependent manner
Authors: Marianne R. Spalinger, Silvia Lang, Claudia Gottier, Xuezhi Dai, David J. Rawlings, Andrew C. Chan, Gerhard Rogler, Michael Scharl - Autophagy 2017 cited by 129
- pEVL: A Linear Plasmid for Generating mRNA IVT Templates With Extended Encoded Poly(A) Sequences
Authors: Alexandra E. Grier, Stephen Burleigh, Jaya Sahni, Courtnee Clough, Victoire Cardot‐Ruffino, Dongwook C. Choe, Michelle C. Krutein, David J. Rawlings, Michael C. Jensen, Andrew M. Scharenberg, Kyle Jacoby - Molecular Therapy — Nucleic Acids 2016 cited by 88
- GNTI-122: an autologous antigen-specific engineered Treg cell therapy for type 1 diabetes
Authors: Gene Uenishi, Marko Repic, Jennifer Yam, Ashley E. Landuyt, Priya Saikumar Lakshmi, Tingxi Guo, Payam Zarin, Martina Sassone‐Corsi, Adam Chicoine, Hunter Kellogg, Martina S. Hunt, Travis Drow, Ritika Tewari, Peter J. Cook, Soo Jung Yang, Karen Cerosaletti, Darius Schweinoch, Benjamin Guiastrennec, Eddie A. James, Chandra Patel, Tiffany F. Chen, Jane H. Buckner, David J. Rawlings, Thomas J. Wickham, Karen T. Mueller - JCI Insight 2024 cited by 50
- Tracking genome engineering outcome at individual DNA breakpoints
Authors: Michael T. Certo, Byoung Y. Ryu, James Annis, Mikhail Garibov, Jordan Jarjour, David J. Rawlings, Andrew M. Scharenberg - Nature Methods 2011 cited by 334
- A RANKL–PKCβ–TFEB signaling cascade is necessary for lysosomal biogenesis in osteoclasts
Authors: Mathieu Ferron, Carmine Settembre, Junko Shimazu, Julie Lacombe, Shigeaki Kato, David J. Rawlings, Andrea Ballabio, Gérard Karsenty - Genes & Development 2013 cited by 177
- Multiplexed Functional Assessment of Genetic Variants in CARD11
Authors: Iana Meitlis, Eric J. Allenspach, Bradly M. Bauman, Isabelle Phan, Gina Dabbah, Erica G. Schmitt, Nathan D. Camp, Troy R. Torgerson, Deborah A. Nickerson, Michael J. Bamshad, David Hagin, Christopher R. Luthers, Jeffrey R. Stinson, Jessica Gray, Ingrid Lundgren, Joseph A. Church, Manish J. Butte, Mike B. Jordan, Seema S. Aceves, Daniella M. Schwartz, Joshua D. Milner, Susan Schuval, Suzanne Skoda‐Smith, Megan A. Cooper, Lea M. Starita, David J. Rawlings, Andrew L. Snow, Richard G. James - The American Journal of Human Genetics 2020 cited by 81
- Interleukin-4 downregulates transcription factor BCL6 to promote memory B cell selection in germinal centers
Authors: Laila Shehata, Christopher D. Thouvenel, Brian D. Hondowicz, Lucia A. Pew, Gretchen Harms Pritchard, David J. Rawlings, Jinyong Choi, Marion Pepper - Immunity 2024 cited by 49
- Dual-locus, dual-HDR editing permits efficient generation of antigen-specific regulatory T cells with robust suppressive activity
Authors: Martina S. Hunt, Soo Jung Yang, Emma Mortensen, Ahmad Boukhris, Jane H. Buckner, Peter J. Cook, David J. Rawlings - Molecular Therapy 2023 cited by 22
- Opposing Impact of B Cell–Intrinsic TLR7 and TLR9 Signals on Autoantibody Repertoire and Systemic Inflammation
Authors: Shaun W. Jackson, Nicole E. Scharping, Nikita Kolhatkar, Socheath Khim, Marc A. Schwartz, Quan‐Zhen Li, Kelly L. Hudkins, Charles E. Alpers, Denny Liggitt, David J. Rawlings - The Journal of Immunology 2014 cited by 165
- Ex vivo engineered human plasma cells exhibit robust protein secretion and long-term engraftment in vivo
Authors: Rene Yu-Hong Cheng, King L. Hung, Tingting Zhang, Claire M. Stoffers, Andee R. Ott, Emmaline R. Suchland, Nathan D. Camp, Iram Khan, Swati Singh, Ying-Jen Yang, David J. Rawlings, Richard G. James - Nature Communications 2022 cited by 56
- Novel Suppressive Function of Transitional 2 B Cells in Experimental Arthritis
Authors: J. Grimley Evans, Adriana Karina Chávez-Rueda, Ayad Eddaoudi, Almut Meyer‐Bahlburg, David J. Rawlings, Michael R. Ehrenstein, Claudia Mauri - The Journal of Immunology 2007 cited by 551
