David L. Sacks
Active 1982–2025
- 129
- Papers
- 25,520
- Citations
- 95
- h-index
- 127
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine57.5%
- Immunology and Microbiology30.5%
- Biochemistry, Genetics and Molecular Biology7.3%
- Agricultural and Biological Sciences1.7%
- Neuroscience0.8%
- Chemistry0.4%
- Other1.8%
Topics
- Research on Leishmaniasis Studies17.1%
- Trypanosoma species research and implications11.1%
- Immune Cell Function and Interaction6.5%
- T-cell and B-cell Immunology5.7%
- Immunotherapy and Immune Responses5%
- Parasites and Host Interactions3.8%
- Other50.8%
Coauthors
- Yasmine Belkaid15
- Shaden Kamhawi14
- Shyam Sundar14
- Salvatore J. Turco12
- Susana Méndez12
- Nathan C. Peters11
- Phillip G. Lawyer11
- Stephen M. Beverley10
- Govind B. Modi9
- Om Prakash Singh9
- Susanne Nylén9
- Audrey Romano8
- Edgar Rowton8
- Ehud Inbar8
- Sang Hun Lee8
- Tiago Rodrigues Ferreira8
- Kashinath Ghosh7
- Robert A. Seder7
- Andrea Paun6
- Deborah E. Dobson6
- Jahangheer Shaik6
- Rajiv Kumar6
- Alain Debrabant5
- Alan Sher5
All papers
- In Vivo Imaging Reveals an Essential Role for Neutrophils in Leishmaniasis Transmitted by Sand Flies
Authors: Nathan C. Peters, Jackson G. Egen, Nagila Secundino, Alain Debrabant, Nicola Kimblin, Shaden Kamhawi, Phillip G. Lawyer, Michael P. Fay, Ronald N. Germain, David L. Sacks - Science 2008 cited by 840
- M2-like, dermal macrophages are maintained via IL-4/CCL24–mediated cooperative interaction with eosinophils in cutaneous leishmaniasis
Authors: Sang Hun Lee, Mariana M. Chaves, Olena Kamenyeva, Pedro Henrique Gazzinelli-Guimarães, Byunghyun Kang, Gabriela Pessenda, Katiuska Passelli, Fabienne Tacchini‐Cottier, Juraj Kabát, Elizabeth A. Jacobsen, Thomas B. Nutman, David L. Sacks - Science Immunology 2020 cited by 92
- CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity
Authors: Yasmine Belkaid, Ciriaco A. Piccirillo, Susana Méndez, Ethan M. Shevach, David L. Sacks - Nature 2002 cited by 1,717
- Xenodiagnosis to evaluate the infectiousness of humans to sandflies in an area endemic for visceral leishmaniasis in Bihar, India: a transmission-dynamics study
Authors: Om Prakash Singh, Puja Tiwary, Anurag Kumar Kushwaha, Shakti Kumar Singh, Dhiraj Kumar Singh, Phillip G. Lawyer, Edgar Rowton, Rahul Chaubey, Abhishek Kumar Singh, Tulika Kumari, Michael P. Fay, Jaya Chakravarty, David L. Sacks, Shyam Sundar - The Lancet Microbe 2021 cited by 91
- Interleukin-10 and the pathogenesis of human visceral leishmaniasis
Authors: Susanne Nylén, David L. Sacks - Trends in Immunology 2007 cited by 377
- Dermis resident macrophages orchestrate localized ILC2 eosinophil circuitries to promote non-healing cutaneous leishmaniasis
Authors: Sang Hun Lee, Byunghyun Kang, Olena Kamenyeva, Tiago Rodrigues Ferreira, Kyoungin Cho, Jaspal S. Khillan, Juraj Kabát, Brian L. Kelsall, David L. Sacks - Nature Communications 2023 cited by 32
- Mannose receptor high, M2 dermal macrophages mediate nonhealing Leishmania major infection in a Th1 immune environment
Authors: Sang Hun Lee, Mélanie Charmoy, Audrey Romano, Andrea Paun, Mariana M. Chaves, Frederick O. Cope, David Ralph, David L. Sacks - The Journal of Experimental Medicine 2017 cited by 118
- Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis
Authors: Rajiv Kumar, Patrick T. Bunn, Siddharth Singh, Susanna S. Ng, Marcela Montes de, Fabian de Labastida Rivera, Shashi Bhushan Chauhan, Neetu Singh, Rebecca J. Faleiro, Chelsea L. Edwards, Teija Frame, Meru Sheel, Rebecca Austin, Steven Lane, Tobias Bald, Mark J. Smyth, Geoffrey R. Hill, Shannon E. Best, Ashraful Haque, Dillon Corvino, Nicola Waddell, Lambross T. Koufariotis, Pamela Mukhopadhay, Madhukar Rai, Jaya Chakravarty, Om Prakash Singh, David L. Sacks, Susanne Nylén, Jude E. Uzonna, Shyam Sundar, Christian Engwerda - Cell Reports 2020 cited by 73
- The immunology of susceptibility and resistance to Leishmania major in mice
Authors: David L. Sacks, Nancy Noben-Trauth - Nature reviews. Immunology 2002 cited by 1,203
- Whole genome sequencing of experimental hybrids supports meiosis-like sexual recombination in Leishmania
Authors: Ehud Inbar, Jahangheer Shaik, Stefano Iantorno, Audrey Romano, Chukwunonso O. Nzelu, Katherine Owens, Mandy Sanders, Deborah E. Dobson, James A. Cotton, Michael E. Grigg, Stephen M. Beverley, David L. Sacks - PLoS Genetics 2019 cited by 95
- The role of dermis resident macrophages and their interaction with neutrophils in the early establishment of Leishmania major infection transmitted by sand fly bite
Authors: Mariana M. Chaves, Sang Hun Lee, Olena Kamenyeva, Kashinath Ghosh, Nathan C. Peters, David L. Sacks - PLoS Pathogens 2020 cited by 68
- Demonstration of Genetic Exchange During Cyclical Development of Leishmania in the Sand Fly Vector
Authors: Natalia S. Akopyants, Nicola Kimblin, Nagila Secundino, Rachel L. Patrick, Nathan C. Peters, Phillip G. Lawyer, Deborah E. Dobson, Stephen M. Beverley, David L. Sacks - Science 2009 cited by 336
- The midgut microbiota plays an essential role in sand fly vector competence forLeishmania major
Authors: Isabelle Louradour, Carolina Cunha Monteiro, Ehud Inbar, Kashinath Ghosh, Richard M. Merkhofer, Phillip G. Lawyer, Andrea Paun, Margery Smelkinson, Nágila Francinete Costa Secundino, Michael D. Lewis, Dinesh Erram, Ludek Zurek, David L. Sacks - Cellular Microbiology 2017 cited by 97
- Stress conditions promote Leishmania hybridization in vitro marked by expression of the ancestral gamete fusogen HAP2 as revealed by single-cell RNA-seq
Authors: Isabelle Louradour, Tiago Rodrigues Ferreira, Emma Duge, Nadira D. Karunaweera, Andrea Paun, David L. Sacks - eLife 2022 cited by 43
- Self-Hybridization in Leishmania major
Authors: Tiago Rodrigues Ferreira, Ehud Inbar, Jahangheer Shaik, Brendan M. Jeffrey, Kashinath Ghosh, Deborah E. Dobson, Stephen M. Beverley, David L. Sacks - mBio 2022 cited by 19
- Molecular Aspects of Parasite-Vector and Vector-Host Interactions in Leishmaniasis
Authors: David L. Sacks, Shaden Kamhawi - Annual Review of Microbiology 2001 cited by 430
- CD8 T Cell Exhaustion in Human Visceral Leishmaniasis
Authors: Shalini Gautam, Rajiv Kumar, Neetu Singh, Abhishek Kumar Singh, Madhukar Rai, David L. Sacks, Shyam Sundar, Susanne Nylén - The Journal of Infectious Diseases 2013 cited by 139
- The Transcriptome ofLeishmania majorDevelopmental Stages in Their Natural Sand Fly Vector
Authors: Ehud Inbar, V. Keith Hughitt, Laura A. L. Dillon, Kashinath Ghosh, Najib M. El-Sayed, David L. Sacks - mBio 2017 cited by 108
- Xenodiagnosis to address key questions in visceral leishmaniasis control and elimination
Authors: Om Prakash Singh, Epco Hasker, Marleen Boelaert, David L. Sacks, Shyam Sundar - PLoS neglected tropical diseases 2020 cited by 40
- CD4+CD25−Foxp3− Th1 cells are the source of IL-10–mediated immune suppression in chronic cutaneous leishmaniasis
Authors: Charles Anderson, Mohammed Oukka, Vijay J. Kuchroo, David L. Sacks - The Journal of Experimental Medicine 2007 cited by 566
- The Role of Interleukin (IL)-10 in the Persistence of Leishmania major in the Skin after Healing and the Therapeutic Potential of Anti–IL-10 Receptor Antibody for Sterile Cure
Authors: Yasmine Belkaid, Karl F. Hoffmann, Susana Méndez, Shaden Kamhawi, Mark C. Udey, Tom A. Wynn, David L. Sacks - The Journal of Experimental Medicine 2001 cited by 552
- Splenic accumulation of IL-10 mRNA in T cells distinct from CD4+CD25+ (Foxp3) regulatory T cells in human visceral leishmaniasis
Authors: Susanne Nylén, Radheshyam Maurya, Liv Eidsmo, Krishna Das Manandhar, Shyam Sundar, David L. Sacks - The Journal of Experimental Medicine 2007 cited by 326
- A Role for Insect Galectins in Parasite Survival
Authors: Shaden Kamhawi, Marcelo Ramalho-Ortigão, Van My Pham, Sanjeev Kumar, Phillip G. Lawyer, Salvatore J. Turco, Carolina Barillas‐Mury, David L. Sacks, Jesús G. Valenzuela - Cell 2004 cited by 268
- Gene Expression in Leishmania Is Regulated Predominantly by Gene Dosage
Authors: Stefano Iantorno, Caroline Durrant, Asis Khan, Mandy Sanders, Stephen M. Beverley, Wesley C. Warren, Matthew Berriman, David L. Sacks, James A. Cotton, Michael E. Grigg - mBio 2017 cited by 128
