David P. Fairlie
Active 1981–2025
- Also published as
- David P Fairlie
- 195
- Papers
- 30,150
- Citations
- 98
- h-index
- 190
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology33.8%
- Medicine31.8%
- Immunology and Microbiology19.4%
- Chemistry2.7%
- Computer Science2.6%
- Neuroscience2.2%
- Other7.5%
Topics
- Immune Cell Function and Interaction4.1%
- Chemical Synthesis and Analysis3.9%
- Alzheimer's disease research and treatments3.7%
- Computational Drug Discovery Methods2.8%
- T-cell and B-cell Immunology2.5%
- Histone Deacetylase Inhibitors Research2.4%
- Other80.6%
Coauthors
- James McCluskey43
- Ligong Liu43
- Jeffrey Y. W. Mak42
- Jamie Rossjohn34
- Alexandra J. Corbett29
- Sidonia B. G. Eckle27
- Robert C. Reid26
- Zhenjun Chen26
- Bronwyn S. Meehan21
- Dale I. Godfrey19
- Junxian Lim18
- Giovanni Abbenante15
- Matthew J. Sweet15
- Abishek Iyer14
- Weijun Xu14
- Huy N. Hoang13
- Lars Kjer‐Nielsen13
- Timothy A. Hill13
- Huimeng Wang12
- Joel D. A. Tyndall12
- Martin J. Stoermer12
- Andrew J. Lucke11
- Jacky Y. Suen11
- Nicholas A. Gherardin11
All papers
- The Future of Peptide‐based Drugs
Authors: David J. Craik, David P. Fairlie, Spiros Liras, David A. Price - Chemical Biology & Drug Design 2012 cited by 1,956
- MR1 presents microbial vitamin B metabolites to MAIT cells
Authors: Lars Kjer‐Nielsen, Onisha Patel, Alexandra J. Corbett, Jérôme Le Nours, Bronwyn S. Meehan, Ligong Liu, Mugdha Bhati, Zhenjun Chen, Lyudmila Kostenko, Rangsima Reantragoon, Nicholas A. Williamson, Anthony W. Purcell, Nadine L. Dudek, Malcolm J. McConville, Richard A. J. O’Hair, George N. Khairallah, Dale I. Godfrey, David P. Fairlie, Jamie Rossjohn, James McCluskey - Nature 2012 cited by 1,363
- T-cell activation by transitory neo-antigens derived from distinct microbial pathways
Authors: Alexandra J. Corbett, Sidonia B. G. Eckle, Richard W. Birkinshaw, Ligong Liu, Onisha Patel, Jennifer Mahony, Zhenjun Chen, Rangsima Reantragoon, Bronwyn S. Meehan, Hanwei Cao, Nicholas A. Williamson, Richard A. Strugnell, Douwe van Sinderen, Jeffrey Y. W. Mak, David P. Fairlie, Lars Kjer‐Nielsen, Jamie Rossjohn, James McCluskey - Nature 2014 cited by 903
- Taking the Myc out of cancer: toward therapeutic strategies to directly inhibit c-Myc
Authors: Sarah K. Madden, Aline D. de Araujo, Mara Gerhardt, David P. Fairlie, Jody M. Mason - Molecular Cancer 2021 cited by 408
- Alpha-synuclein structure and Parkinson’s disease – lessons and emerging principles
Authors: Richard M. Meade, David P. Fairlie, Jody M. Mason - Molecular Neurodegeneration 2019 cited by 418
- Orally Absorbed Cyclic Peptides
Authors: Daniel S. Nielsen, Nicholas E. Shepherd, Weijun Xu, Andrew J. Lucke, Martin J. Stoermer, David P. Fairlie - Chemical Reviews 2017 cited by 443
- Systemic delivery of peptides by the oral route: Formulation and medicinal chemistry approaches
Authors: David J. Brayden, Timothy A. Hill, David P. Fairlie, Sam Maher, Randall J. Mrsny - Advanced Drug Delivery Reviews 2020 cited by 245
- Histone deacetylases as regulators of inflammation and immunity
Authors: Melanie R. Shakespear, Maria A. Halili, Katharine M. Irvine, David P. Fairlie, Matthew J. Sweet - Trends in Immunology 2011 cited by 542
- Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells
Authors: Rangsima Reantragoon, Alexandra J. Corbett, Isaac G. Sakala, Nicholas A. Gherardin, John B. Furness, Zhenjun Chen, Sidonia B. G. Eckle, Adam P. Uldrich, Richard W. Birkinshaw, Onisha Patel, Lyudmila Kostenko, Bronwyn S. Meehan, Katherine Kedzierska, Ligong Liu, David P. Fairlie, Ted H. Hansen, Dale I. Godfrey, Jamie Rossjohn, James McCluskey, Lars Kjer‐Nielsen - The Journal of Experimental Medicine 2013 cited by 598
- A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells
Authors: Sidonia B. G. Eckle, Richard W. Birkinshaw, Lyudmila Kostenko, Alexandra J. Corbett, Hamish E. G. McWilliam, Rangsima Reantragoon, Zhenjun Chen, Nicholas A. Gherardin, Travis Beddoe, Ligong Liu, Onisha Patel, Bronwyn S. Meehan, David P. Fairlie, Jóse A. Villadangos, Dale I. Godfrey, Lars Kjer‐Nielsen, James McCluskey, Jamie Rossjohn - The Journal of Experimental Medicine 2014 cited by 308
- A three-stage intrathymic development pathway for the mucosal-associated invariant T cell lineage
Authors: Hui‐Fern Koay, Nicholas A. Gherardin, Anselm Enders, Liyen Loh, Laura K. Mackay, Catarina F. Almeida, Brendan E. Russ, Claudia A. Nold‐Petry, Marcel F. Nold, Sammy Bedoui, Zhenjun Chen, Alexandra J. Corbett, Sidonia B. G. Eckle, Bronwyn S. Meehan, Yves d’Udekem, Igor E. Konstantinov, Martha Lappas, Ligong Liu, Christopher C. Goodnow, David P. Fairlie, Jamie Rossjohn, Mark M. W. Chong, Katherine Kedzierska, Stuart P. Berzins, Gabrielle T. Belz, James McCluskey, Adam P. Uldrich, Dale I. Godfrey, Daniel G. Pellicci - Nature Immunology 2016 cited by 366
- Identification of phenotypically and functionally heterogeneous mouse mucosal-associated invariant T cells using MR1 tetramers
Authors: Azad Rahimpour, Hui‐Fern Koay, Anselm Enders, Rhiannon Clanchy, Sidonia B. G. Eckle, Bronwyn S. Meehan, Zhenjun Chen, Belinda Whittle, Ligong Liu, David P. Fairlie, Christopher C. Goodnow, James McCluskey, Jamie Rossjohn, Adam P. Uldrich, Daniel G. Pellicci, Dale I. Godfrey - The Journal of Experimental Medicine 2015 cited by 383
- Constraining Cyclic Peptides To Mimic Protein Structure Motifs
Authors: Timothy A. Hill, Nicholas E. Shepherd, Frederik Diness, David P. Fairlie - Angewandte Chemie International Edition 2014 cited by 414
- The intracellular pathway for the presentation of vitamin B–related antigens by the antigen-presenting molecule MR1
Authors: Hamish E. G. McWilliam, Sidonia B. G. Eckle, Alex Theodossis, Ligong Liu, Zhenjun Chen, Jacinta M. Wubben, David P. Fairlie, Richard A. Strugnell, Justine D. Mintern, James McCluskey, Jamie Rossjohn, Jóse A. Villadangos - Nature Immunology 2016 cited by 185
- Human blood MAIT cell subsets defined using MR1 tetramers
Authors: Nicholas A. Gherardin, Michael N. T. Souter, Hui‐Fern Koay, Kirstie M. Mangas, Torsten Seemann, Timothy P. Stinear, Sidonia B. G. Eckle, Stuart P. Berzins, Yves d’Udekem, Igor E. Konstantinov, David P. Fairlie, David S Ritchie, Paul J. Neeson, Daniel G. Pellicci, Adam P. Uldrich, James McCluskey, Dale I. Godfrey - Immunology and Cell Biology 2018 cited by 272
- Sulfated bile acid is a host-derived ligand for MAIT cells
Authors: E. Ito, Shinsuke Inuki, Yoshihiro Izumi, Masatomo Takahashi, Yuki Dambayashi, Lisa Ciacchi, Wael Awad, Ami Takeyama, Kensuke Shibata, Shotaro Mori, Jeffrey Y. W. Mak, David P. Fairlie, Takeshi Bamba, Eri Ishikawa, Masamichi Nagae, Jamie Rossjohn, Sho Yamasaki - Science Immunology 2024 cited by 67
- Stabilizing short-lived Schiff base derivatives of 5-aminouracils that activate mucosal-associated invariant T cells
Authors: Jeffrey Y. W. Mak, Weijun Xu, Robert C. Reid, Alexandra J. Corbett, Bronwyn S. Meehan, Huimeng Wang, Zhenjun Chen, Jamie Rossjohn, James McCluskey, Ligong Liu, David P. Fairlie - Nature Communications 2017 cited by 161
- Single Turn Peptide Alpha Helices with Exceptional Stability in Water
Authors: Nicholas E. Shepherd, Huy N. Hoang, Giovanni Abbenante, David P. Fairlie - Journal of the American Chemical Society 2005 cited by 323
- Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells
Authors: Andrew N. Keller, Sidonia B. G. Eckle, Weijun Xu, Ligong Liu, Victoria A. Hughes, Jeffrey Y. W. Mak, Bronwyn S. Meehan, Troi Pediongco, Richard W. Birkinshaw, Zhenjun Chen, Huimeng Wang, Criselle D’Souza, Lars Kjer‐Nielsen, Nicholas A. Gherardin, Dale I. Godfrey, Lyudmila Kostenko, Alexandra J. Corbett, Anthony W. Purcell, David P. Fairlie, James McCluskey, Jamie Rossjohn - Nature Immunology 2017 cited by 236
- Stapling peptides using cysteine crosslinking
Authors: David P. Fairlie, Aline D. de Araujo - Biopolymers 2016 cited by 137
- MAIT cells regulate NK cell-mediated tumor immunity
Authors: Emma V. Petley, Hui‐Fern Koay, Melissa A. Henderson, Kevin Sek, Kirsten L. Todd, Simon P. Keam, Junyun Lai, Imran G. House, Jasmine Li, Magnus Zethoven, Amanda X. Y. Chen, Amanda J. Oliver, Jessica Michie, Andrew J. Freeman, Lauren Giuffrida, Jack D. Chan, Angela Pizzolla, Jeffrey Y. W. Mak, Timothy R. McCulloch, Fernando Souza-Fonseca-Guimarães, Conor J. Kearney, Rosemary Millen, Robert G. Ramsay, Nicholas D. Huntington, James McCluskey, Jane Oliaro, David P. Fairlie, Paul J. Neeson, Dale I. Godfrey, Paul A. Beavis, Phillip K. Darcy - Nature Communications 2021 cited by 104
- Function, structure and therapeutic potential of complement C5a receptors
Authors: Peter N. Monk, A‐M Scola, Praveen K. Madala, David P. Fairlie - British Journal of Pharmacology 2007 cited by 397
- Mucosal-associated invariant T-cell activation and accumulation after in vivo infection depends on microbial riboflavin synthesis and co-stimulatory signals
Authors: Zhenjun Chen, Huimeng Wang, Criselle D’Souza, Shicheng Sun, Lyudmila Kostenko, Sidonia B. G. Eckle, Bronwyn S. Meehan, David C. Jackson, Richard A. Strugnell, Hao Cao, Nancy Wang, David P. Fairlie, Ligong Liu, Dale I. Godfrey, Jamie Rossjohn, James McCluskey, Alexandra J. Corbett - Mucosal Immunology 2016 cited by 275
- The molecular basis underpinning the potency and specificity of MAIT cell antigens
Authors: Wael Awad, Geraldine Jia Ming Ler, Weijun Xu, Andrew N. Keller, Jeffrey Y. W. Mak, Xin Yi Lim, Ligong Liu, Sidonia B. G. Eckle, Jérôme Le Nours, James McCluskey, Alexandra J. Corbett, David P. Fairlie, Jamie Rossjohn - Nature Immunology 2020 cited by 86
