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David T. Denhardt

Active 1965–2017

76
Papers
22,159
Citations
76
h-index
76
i10-index

Citations

Citations per year for David T. Denhardt1966: 4 citations1967: 9 citations1968: 16 citations1969: 7 citations1970: 15 citations1971: 16 citations1972: 9 citations1973: 12 citations1974: 13 citations1975: 15 citations1976: 14 citations1977: 32 citations1978: 49 citations1979: 64 citations1980: 84 citations1981: 83 citations1982: 83 citations1983: 103 citations1984: 115 citations1985: 67 citations1986: 80 citations1987: 73 citations1988: 70 citations1989: 94 citations1990: 88 citations1991: 88 citations1992: 90 citations1993: 84 citations1994: 95 citations1995: 144 citations1996: 100 citations1997: 172 citations1998: 140 citations1999: 183 citations2000: 202 citations2001: 228 citations2002: 210 citations2003: 262 citations2004: 248 citations2005: 248 citations2006: 239 citations2007: 232 citations2008: 203 citations2009: 204 citations2010: 197 citations2011: 147 citations2012: 96 citations2013: 101 citations2014: 127 citations2015: 85 citations2016: 90 citations2017: 75 citations2018: 70 citations2019: 250 citations2020: 255 citations2021: 216 citations2022: 188 citations2023: 115 citations2024: 133 citations2025: 65 citations

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 2,441 citing papers, 40.9% of this breakdownUnited Kingdom: 377 citing papers, 6.3% of this breakdownChina: 345 citing papers, 5.8% of this breakdownGermany: 339 citing papers, 5.7% of this breakdownJapan: 330 citing papers, 5.6% of this breakdownCanada: 318 citing papers, 5.3% of this breakdownFrance: 194 citing papers, 3.3% of this breakdownItaly: 139 citing papers, 2.3% of this breakdownAustralia: 132 citing papers, 2.2% of this breakdownSwitzerland: 124 citing papers, 2.1% of this breakdownNetherlands: 107 citing papers, 1.8% of this breakdownSweden: 85 citing papers, 1.4% of this breakdown
0%40.9%Other 17.3%

Institutions

Fields

  • Medicine47.5%
  • Biochemistry, Genetics and Molecular Biology35.9%
  • Immunology and Microbiology4.5%
  • Neuroscience2.7%
  • Agricultural and Biological Sciences2.2%
  • Environmental Science2.1%
  • Other5.1%

Topics

  • Bone and Dental Protein Studies6.7%
  • Bone Metabolism and Diseases2.7%
  • Protease and Inhibitor Mechanisms2.5%
  • Cell Adhesion Molecules Research2%
  • dental development and anomalies1.6%
  • RNA and protein synthesis mechanisms1.5%
  • Other83%

Coauthors

All papers

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  1. Osteopontin as a means to cope with environmental insults: regulation of inflammation, tissue remodeling, and cell survival

    Authors: David T. Denhardt, Masaki Noda, Anthony O’Regan, Dubravko Pavlin, Jeffrey S. Berman - Journal of Clinical Investigation 2001 cited by 1,064

  2. Eta-1 (Osteopontin): An Early Component of Type-1 (Cell-Mediated) Immunity

    Authors: Samy Ashkar, Georg F. Weber, Vassiliki Panoutsakopoulou, Marie Sanchirico, Marianne Jansson, Samer Zawaideh, Susan R. Rittling, David T. Denhardt, Melvin J. Glimcher, Harvey Cantor - Science 2000 cited by 1,133

  3. THE INFLUENCE OF THE PROINFLAMMATORY CYTOKINE, OSTEOPONTIN, ON AUTOIMMUNE DEMYELINATING DISEASE

    Authors: Dorothée Chabas, Sergio E. Baranzini, D. Mitchell, Claude C.A. Bernard, Susan R. Rittling, David T. Denhardt, Raymond A. Sobel, Christopher Lock, Marcela V. Karpuj, Rosetta Pedotti, Renu A. Heller, Jorge R. Oksenberg, Lawrence Steinman - International Conference on Osteopontin and SIBLING (Small Integrin-Binding Ligand, International Conference on Osteopontin and SIBLING (Small Integrin-Binding Ligand, N-linked Glycoprotein) Proteins, 2002 2001 cited by 827

  4. Osteopontin: Role in immune regulation and stress responses

    Authors: Kathryn X. Wang, David T. Denhardt - Cytokine & Growth Factor Reviews 2008 cited by 678

  5. Osteopontin, a key component of the hematopoietic stem cell niche and regulator of primitive hematopoietic progenitor cells

    Authors: Susan K. Nilsson, Hayley M. Johnston, Genevieve Whitty, Brenda Williams, Ryan J. Webb, David T. Denhardt, Ivan Bertoncello, Linda J. Bendall, Paul J. Simmons, David N. Haylock - Blood 2005 cited by 787

  6. An Osteopontin-Integrin Interaction Plays a Critical Role in Directing Adipogenesis and Osteogenesis by Mesenchymal Stem Cells

    Authors: Qing Chen, Peishun Shou, Liying Zhang, Chunliang Xu, Chunxing Zheng, Yanyan Han, Wenzhao Li, Yin Huang, Xiaoren Zhang, Changshun Shao, Arthur I. Roberts, Arnold B. Rabson, Guangwen Ren, Yi Zhang, Ying Wang, David T. Denhardt, Yufang Shi - Stem Cells 2013 cited by 251

  7. Osteopontin Deficiency Attenuates Atherosclerosis in Female Apolipoprotein E–Deficient Mice

    Authors: Yutaka Matsui, Susan R. Rittling, Hiroshi Okamoto, Manabu Inobe, Nan Jia, Toshihiro Shimizu, M Akino, Takeshi Sugawara, Junko Morimoto, Chiemi Kimura, Shigeyuki Kon, David T. Denhardt, Akira Kitabatake, Toshimitsu Uede - Arteriosclerosis Thrombosis and Vascular Biology 2003 cited by 198

  8. Osteopontin: a protein with diverse functions

    Authors: David T. Denhardt, Xiaojia Guo - The FASEB Journal 1993 cited by 1,082

  9. Osteopontin expression and function: Role in bone remodeling

    Authors: David T. Denhardt, Masaki Noda - Journal of Cellular Biochemistry 1998 cited by 425

  10. Control of osteopontin signaling and function by post‐translational phosphorylation and protein folding

    Authors: Christian C. Kazanecki, Dana J. Uzwiak, David T. Denhardt - Journal of Cellular Biochemistry 2007 cited by 280

  11. Mice Lacking Osteopontin Show Normal Development and Bone Structure but Display Altered Osteoclast Formation In Vitro

    Authors: Susan R. Rittling, Hiroko Matsumoto, Marc D. McKee, Antonio Nanci, Xiao-Rong An, Kristine E. Novick, Aaron J. Kowalski, Masaki Noda, David T. Denhardt - Journal of Bone and Mineral Research 1998 cited by 431

  12. Role of Osteopontin in Cardiac Fibrosis and Remodeling in Angiotensin II-Induced Cardiac Hypertrophy

    Authors: Yutaka Matsui, Nan Jia, Hiroshi Okamoto, Shigeyuki Kon, Hisao Onozuka, M Akino, Lizhi Liu, Junko Morimoto, Susan R. Rittling, David T. Denhardt, Akira Kitabatake, Toshimitsu Uede - Hypertension 2004 cited by 187

  13. Enhancement of Osteoclastic Bone Resorption and Suppression of Osteoblastic Bone Formation in Response to Reduced Mechanical Stress Do Not Occur in the Absence of Osteopontin

    Authors: Muneaki Ishijima, Susan R. Rittling, Teruhito Yamashita, Kunikazu Tsuji, Hisashi Kurosawa, Akira Nifuji, David T. Denhardt, Masaki Noda - The Journal of Experimental Medicine 2001 cited by 239

  14. Thrombin-cleaved osteopontin regulates hemopoietic stem and progenitor cell functions through interactions with α9β1 and α4β1 integrins

    Authors: Jochen Grassinger, David N. Haylock, Melonie J. Storan, Gemma O. Haines, Brenda Williams, Genevieve Whitty, Andrew Vinson, Cheang Ly Be, Songhui Li, Esben S. Sørensen, Patrick Tam, David T. Denhardt, Dean Sheppard, Peter Choong, Susan K. Nilsson - Blood 2009 cited by 200

  15. Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques.

    Authors: Cecilia M. Giachelli, Na-Young Bae, M Almeida, David T. Denhardt, Charles E. Alpers, Stephen M. Schwartz - Journal of Clinical Investigation 1993 cited by 644

  16. Role of Osteopontin in Cellular Signaling and Toxicant Injury

    Authors: David T. Denhardt, Cecilia M. Giachelli, Susan R. Rittling - The Annual Review of Pharmacology and Toxicology 2001 cited by 359

  17. Osteopontin Deficiency Produces Osteoclast Dysfunction Due to Reduced CD44 Surface Expression

    Authors: Meenakshi A. Chellaiah, N. Kizer, R. Biswas, Ulises Alvarez, Jena Strauss‐Schoenberger, Leonard Rifas, Susan R. Rittling, David T. Denhardt, Keith A. Hruska - Molecular Biology of the Cell 2003 cited by 246

  18. Unloading Induces Osteoblastic Cell Suppression and Osteoclastic Cell Activation to Lead to Bone Loss via Sympathetic Nervous System

    Authors: Hisataka Kondo, Akira Nifuji, Shu Takeda, Yoichi Ezura, Susan R. Rittling, David T. Denhardt, Kazuhisa Nakashima, Gérard Karsenty, Masaki Noda - Journal of Biological Chemistry 2005 cited by 209

  19. Osteopontin as a Mediator of NKT Cell Function in T Cell-Mediated Liver Diseases

    Authors: Hongyan Diao, Shigeyuki Kon, Kazuya Iwabuchi, Chiemi Kimura, Junko Morimoto, Daisuke Ito, Tatsuya Segawa, Masahiro Maeda, Junji Hamuro, Toshinori Nakayama, Masaru Taniguchi, Hideo Yagita∥, Luc Van Kaer, Kazunori Onoé, David T. Denhardt, Susan R. Rittling, Toshimitsu Uede - Immunity 2004 cited by 195

  20. Colocalization of Intracellular Osteopontin With CD44 Is Associated With Migration, Cell Fusion, and Resorption in Osteoclasts

    Authors: Keiko Suzuki, Baoqian Zhu, Susan R. Rittling, David T. Denhardt, Harvey A. Goldberg, Christopher A. McCulloch, Jaro Sodek - Journal of Bone and Mineral Research 2002 cited by 154

  21. Osteopontin-Deficient Mice Exhibit Less Inflammation, Greater Tissue Damage, and Impaired Locomotor Recovery from Spinal Cord Injury Compared with Wild-Type Controls

    Authors: Masayuki Hashimoto, Dongming Sun, Susan R. Rittling, David T. Denhardt, Wise Young - Journal of Neuroscience 2007 cited by 93

  22. Signal-transducing protein phosphorylation cascades mediated by Ras/Rho proteins in the mammalian cell: the potential for multiplex signalling

    Authors: David T. Denhardt - Biochemical Journal 1996 cited by 498

  23. Osteopontin Expression in Osteoblasts and Osteocytes During Bone Formation Under Mechanical Stress in the Calvarial Suture In Vivo

    Authors: Mikihiko Morinobu, Muneaki Ishijima, Susan R. Rittling, Kunikazu Tsuji, Haruyasu Yamamoto, Akira Nifuji, David T. Denhardt, Masaki Noda - Journal of Bone and Mineral Research 2003 cited by 184

  24. Cell Type-specific Post-translational Modifications of Mouse Osteopontin Are Associated with Different Adhesive Properties

    Authors: Brian Christensen, Christian C. Kazanecki, Torben E. Petersen, Susan R. Rittling, David T. Denhardt, Esben S. Sørensen - Journal of Biological Chemistry 2007 cited by 138