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Douglas R. Seals

Active 1983–2025

Also published as
DOUGLAS R. SEALS
233
Papers
39,951
Citations
120
h-index
227
i10-index

Citations

Citations per year for Douglas R. Seals1976: 3 citations1977: 2 citations1979: 1 citations1983: 1 citations1984: 3 citations1985: 9 citations1986: 14 citations1987: 15 citations1988: 19 citations1989: 20 citations1990: 34 citations1991: 58 citations1992: 41 citations1993: 38 citations1994: 36 citations1995: 40 citations1996: 76 citations1997: 70 citations1998: 104 citations1999: 90 citations2000: 163 citations2001: 216 citations2002: 167 citations2003: 244 citations2004: 219 citations2005: 227 citations2006: 215 citations2007: 227 citations2008: 260 citations2009: 290 citations2010: 307 citations2011: 323 citations2012: 330 citations2013: 307 citations2014: 364 citations2015: 337 citations2016: 357 citations2017: 308 citations2018: 421 citations2019: 1,136 citations2020: 1,264 citations2021: 1,321 citations2022: 972 citations2023: 920 citations2024: 1,206 citations2025: 628 citations2026: 27 citations1978: no citations, so this year is not shown1980–1982: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 3,691 citing papers, 29.2% of this breakdownChina: 1,030 citing papers, 8.1% of this breakdownUnited Kingdom: 904 citing papers, 7.1% of this breakdownItaly: 620 citing papers, 4.9% of this breakdownCanada: 586 citing papers, 4.6% of this breakdownAustralia: 530 citing papers, 4.2% of this breakdownGermany: 429 citing papers, 3.4% of this breakdownSpain: 327 citing papers, 2.6% of this breakdownNetherlands: 324 citing papers, 2.6% of this breakdownJapan: 322 citing papers, 2.5% of this breakdownBrazil: 297 citing papers, 2.4% of this breakdownFrance: 294 citing papers, 2.3% of this breakdown
0%29.2%Other 26.1%

Institutions

Fields

  • Medicine68.6%
  • Biochemistry, Genetics and Molecular Biology16.4%
  • Neuroscience5.3%
  • Immunology and Microbiology1.6%
  • Psychology1.6%
  • Nursing1.6%
  • Other4.9%

Topics

  • Cardiovascular and exercise physiology6.5%
  • Heart Rate Variability and Autonomic Control6%
  • Cardiovascular Health and Disease Prevention3.3%
  • Adipose Tissue and Metabolism2.4%
  • Blood Pressure and Hypertension Studies2.1%
  • Physical Activity and Health1.9%
  • Other77.8%

Coauthors

All papers

Open in search
  1. Age-predicted maximal heart rate revisited

    Authors: Hirofumi Tanaka, Kevin D. Monahan, Douglas R. Seals - Journal of the American College of Cardiology 2001 cited by 3,723

  2. Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults

    Authors: Christopher R. Martens, Blair A. Denman, Melissa R. Mazzo, Michael Armstrong, Nichole Reisdorph, Matthew B. McQueen, Michel Chonchol, Douglas R. Seals - Nature Communications 2018 cited by 580

  3. Chronic Supplementation With a Mitochondrial Antioxidant (MitoQ) Improves Vascular Function in Healthy Older Adults

    Authors: Matthew J. Rossman, Jessica R. Santos‐Parker, Chelsea A.C. Steward, Nina Z. Bispham, Lauren M. Cuevas, Hannah L. Rosenberg, Kayla A. Woodward, Michel Chonchol, Rachel A. Gioscia‐Ryan, Michael P. Murphy, Douglas R. Seals - Hypertension 2018 cited by 432

  4. The gut microbiome–derived metabolite trimethylamine N-oxide modulates neuroinflammation and cognitive function with aging

    Authors: Vienna E. Brunt, Thomas J. LaRocca, Amy Bazzoni, Zachary J. Sapinsley, Jill Miyamoto-Ditmon, Rachel A. Gioscia‐Ryan, Andrew P. Neilson, Christopher D. Link, Douglas R. Seals - GeroScience 2020 cited by 185

  5. Trimethylamine-N-Oxide Promotes Age-Related Vascular Oxidative Stress and Endothelial Dysfunction in Mice and Healthy Humans

    Authors: Vienna E. Brunt, Rachel A. Gioscia‐Ryan, Abigail G. Casso, Nicholas S. VanDongen, Brian P. Ziemba, Zachary J. Sapinsley, James J. Richey, Melanie C. Zigler, Andrew P. Neilson, Kevin P. Davy, Douglas R. Seals - Hypertension 2020 cited by 270

  6. Nicotinamide mononucleotide supplementation reverses vascular dysfunction and oxidative stress with aging in mice

    Authors: Natalie E. de Picciotto, Lindsey B. Gano, Lawrence C. Johnson, Christopher R. Martens, Amy L. Sindler, Kathryn F. Mills, Shin‐ichiro Imai, Douglas R. Seals - Aging Cell 2016 cited by 392

  7. Intermittent supplementation with fisetin improves arterial function in old mice by decreasing cellular senescence

    Authors: Sophia Mahoney, Ravinandan Venkatasubramanian, Mary A. Darrah, Katelyn R. Ludwig, Nicholas S. VanDongen, Nathan Greenberg, Abigail G. Longtine, David A. Hutton, Vienna E. Brunt, Judith Campisi, Simon Melov, Douglas R. Seals, Matthew J. Rossman, Zachary S. Clayton - Aging Cell 2023 cited by 89

  8. Suppression of the gut microbiome ameliorates age‐related arterial dysfunction and oxidative stress in mice

    Authors: Vienna E. Brunt, Rachel A. Gioscia‐Ryan, James J. Richey, Melanie C. Zigler, Lauren M. Cuevas, Antonio González, Yoshiki Vázquez‐Baeza, Micah L. Battson, Andrew T. Smithson, Andrew Gilley, Gail Ackermann, Andrew P. Neilson, Tiffany L. Weir, Kevin P. Davy, Rob Knight, Douglas R. Seals - The Journal of Physiology 2019 cited by 177

  9. Mitochondrial contributions to vascular endothelial dysfunction, arterial stiffness, and cardiovascular diseases

    Authors: Danielle L. Kirkman, Austin T. Robinson, Matthew J. Rossman, Douglas R. Seals, David G. Edwards - American Journal of Physiology-Heart and Circulatory Physiology 2021 cited by 134

  10. Cellular Senescence Contributes to Large Elastic Artery Stiffening and Endothelial Dysfunction With Aging: Amelioration With Senolytic Treatment

    Authors: Zachary S. Clayton, Matthew J. Rossman, Sophia Mahoney, Ravinandan Venkatasubramanian, Grace S. Maurer, David A. Hutton, Nicholas S. VanDongen, Nathan Greenberg, Abigail G. Longtine, Katelyn R. Ludwig, Vienna E. Brunt, Thomas J. LaRocca, Judith Campisi, Simon Melov, Douglas R. Seals - Hypertension 2023 cited by 84

  11. Aging and vascular endothelial function in humans

    Authors: Douglas R. Seals, Kristen Jablonski, Anthony J. Donato - Clinical Science 2011 cited by 701

  12. Short-term time-restricted feeding is safe and feasible in non-obese healthy midlife and older adults

    Authors: Christopher R. Martens, Matthew J. Rossman, Melissa R. Mazzo, Lindsey R. Jankowski, Erzsébet Nagy, Blair A. Denman, James J. Richey, Sarah Johnson, Brian P. Ziemba, Yang Wang, Courtney M. Peterson, Michel Chonchol, Douglas R. Seals - GeroScience 2020 cited by 172

  13. Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin

    Authors: Michael Vreones, Maja Mustapić, Ruin Moaddel, Krishna A. Pucha, Jacqueline Lovett, Douglas R. Seals, Dimitrios Kapogiannis, Christopher R. Martens - Aging Cell 2022 cited by 70

  14. Mitochondria‐targeted antioxidant (MitoQ) ameliorates age‐related arterial endothelial dysfunction in mice

    Authors: Rachel A. Gioscia‐Ryan, Thomas J. LaRocca, Amy L. Sindler, Melanie C. Zigler, Michael P. Murphy, Douglas R. Seals - The Journal of Physiology 2014 cited by 257

  15. Endothelial cell senescence with aging in healthy humans: prevention by habitual exercise and relation to vascular endothelial function

    Authors: Matthew J. Rossman, Rachelle E. Kaplon, Sierra D. Hill, Molly N. McNamara, Jessica R. Santos‐Parker, Gary L. Pierce, Douglas R. Seals, Anthony J. Donato - American Journal of Physiology-Heart and Circulatory Physiology 2017 cited by 222

  16. Direct Evidence of Endothelial Oxidative Stress With Aging in Humans

    Authors: Anthony J. Donato, Iratxe Eskurza, Annemarie Silver, Adam Levy, Gary L. Pierce, Phillip E. Gates, Douglas R. Seals - Circulation Research 2007 cited by 556

  17. Dietary Nitrate and Nitric Oxide Metabolism: Mouth, Circulation, Skeletal Muscle, and Exercise Performance

    Authors: Andrew M. Jones, Anni Vanhatalo, Douglas R. Seals, Matthew J. Rossman, Barbora Piknova, Kristin L. Jonvik - Medicine & Science in Sports & Exercise 2020 cited by 141

  18. Gut Microbiome-Derived Metabolite Trimethylamine N-Oxide Induces Aortic Stiffening and Increases Systolic Blood Pressure With Aging in Mice and Humans

    Authors: Vienna E. Brunt, Abigail G. Casso, Rachel A. Gioscia‐Ryan, Zachary J. Sapinsley, Brian P. Ziemba, Zachary S. Clayton, Amy Bazzoni, Nicholas S. VanDongen, James J. Richey, David A. Hutton, Melanie C. Zigler, Andrew P. Neilson, Kevin P. Davy, Douglas R. Seals - Hypertension 2021 cited by 95

  19. Curcumin supplementation improves vascular endothelial function in healthy middle-aged and older adults by increasing nitric oxide bioavailability and reducing oxidative stress

    Authors: Jessica R. Santos‐Parker, Talia R. Strahler, Candace J. Bassett, Nina Z. Bispham, Michel B. Chonchol, Douglas R. Seals - Aging 2017 cited by 207

  20. Physiological geroscience: targeting function to increase healthspan and achieve optimal longevity

    Authors: Douglas R. Seals, Jamie N. Justice, Thomas J. LaRocca - The Journal of Physiology 2015 cited by 308

  21. Aerobic exercise training and vascular function with ageing in healthy men and women

    Authors: Douglas R. Seals, Erzsébet Nagy, Kerrie L. Moreau - The Journal of Physiology 2019 cited by 223

  22. Dietary rapamycin supplementation reverses age‐related vascular dysfunction and oxidative stress, while modulating nutrient‐sensing, cell cycle, and senescence pathways

    Authors: Lisa A. Lesniewski, Douglas R. Seals, Ashley E. Walker, Grant D. Henson, Mark Blimline, Daniel W. Trott, Gary C. Bosshardt, Thomas J. LaRocca, Brooke R. Lawson, Melanie C. Zigler, Anthony J. Donato - Aging Cell 2016 cited by 166

  23. Essential Role of Estrogen for Improvements in Vascular Endothelial Function With Endurance Exercise in Postmenopausal Women

    Authors: Kerrie L. Moreau, Brian L. Stauffer, Wendy M. Kohrt, Douglas R. Seals - The Journal of Clinical Endocrinology & Metabolism 2013 cited by 213

  24. The autophagy enhancer spermidine reverses arterial aging

    Authors: Thomas J. LaRocca, Rachel A. Gioscia‐Ryan, Christopher M. Hearon, Douglas R. Seals - Mechanisms of Ageing and Development 2013 cited by 204