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Edward H. Koo

Active 1988–2024

103
Papers
29,177
Citations
83
h-index
103
i10-index

Citations

Citations per year for Edward H. Koo1971: 1 citations1989: 1 citations1990: 11 citations1991: 57 citations1992: 83 citations1993: 141 citations1994: 199 citations1995: 173 citations1996: 180 citations1997: 228 citations1998: 249 citations1999: 241 citations2000: 291 citations2001: 304 citations2002: 326 citations2003: 369 citations2004: 346 citations2005: 387 citations2006: 417 citations2007: 337 citations2008: 371 citations2009: 386 citations2010: 431 citations2011: 396 citations2012: 486 citations2013: 388 citations2014: 390 citations2015: 312 citations2016: 312 citations2017: 312 citations2018: 239 citations2019: 616 citations2020: 733 citations2021: 648 citations2022: 519 citations2023: 375 citations2024: 492 citations2025: 221 citations2026: 4 citations1972–1988: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 4,322 citing papers, 34.2% of this breakdownGermany: 893 citing papers, 7% of this breakdownChina: 830 citing papers, 6.6% of this breakdownUnited Kingdom: 758 citing papers, 6% of this breakdownCanada: 463 citing papers, 3.6% of this breakdownJapan: 452 citing papers, 3.6% of this breakdownItaly: 446 citing papers, 3.5% of this breakdownFrance: 352 citing papers, 2.8% of this breakdownAustralia: 340 citing papers, 2.7% of this breakdownSweden: 312 citing papers, 2.5% of this breakdownIndia: 267 citing papers, 2.1% of this breakdownBelgium: 259 citing papers, 2% of this breakdown
0%34.2%Other 23.4%

Institutions

Fields

  • Medicine63.5%
  • Biochemistry, Genetics and Molecular Biology20.3%
  • Neuroscience11.8%
  • Computer Science0.9%
  • Immunology and Microbiology0.7%
  • Nursing0.5%
  • Other2.3%

Topics

  • Alzheimer's disease research and treatments21.6%
  • Cholinesterase and Neurodegenerative Diseases5.3%
  • Computational Drug Discovery Methods4.4%
  • Neuroinflammation and Neurodegeneration Mechanisms4%
  • Dementia and Cognitive Impairment Research2.8%
  • Prion Diseases and Protein Misfolding2.3%
  • Other59.6%

Coauthors

All papers

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  1. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

    Authors: Adam C. Naj, Gyungah Jun, Gary W. Beecham, Li‐San Wang, Badri N. Vardarajan, Jacqueline L. Buros, Paul J. Gallins, Joseph D. Buxbaum, Gail P. Jarvik, Paul K. Crane, Eric B. Larson, Thomas D. Bird, Bradley F. Boeve, Neill R. Graff‐Radford, Philip L. De Jager, Denis A. Evans, Julie A. Schneider, Minerva M. Carrasquillo, Nilüfer Ertekin‐Taner, Steven G. Younkin, Carlos Cruchaga, John Kauwe, Petra Nowotny, Patricia Kramer, John Hardy, Matthew J. Huentelman, Amanda Myers, M. Michael Barmada, F. Yesim Demirci, Clinton T. Baldwin, Robert C. Green, Ekaterina Rogaeva, Peter St George‐Hyslop, Steven E. Arnold, Robert C. Barber, Thomas G. Beach, Eileen H. Bigio, James D. Bowen, Adam Boxer, James R. Burke, Nigel J. Cairns, Chris Carlson, Regina M. Carney, Steven L. Carroll, Helena C. Chui, David G. Clark, Jason J. Corneveaux, Carl W. Cotman, Jeffrey L. Cummings, Charles DeCarli, Steven T. DeKosky, Ramon Diaz‐Arrastia, Malcolm Dick, Dennis W. Dickson, William G. Ellis, Kelley M. Faber, Kenneth B. Fallon, Martin R. Farlow, Steven H. Ferris, Matthew P. Frosch, Douglas Galasko, Mary Ganguli, Marla Gearing, Daniel H. Geschwind, Bernardino Ghetti, John R. Gilbert, Sid Gilman, Bruno Giordani, Jonathan D. Glass, John H. Growdon, Ronald L. Hamilton, Lindy E. Harrell, Elizabeth Head, Lawrence S. Honig, Christine M. Hulette, Bradley T. Hyman, Gregory A. Jicha, Lee‐Way Jin, Nancy Johnson, Jason Karlawish, Anna Karydas, Jeffrey Kaye, Ronald Kim, Edward H. Koo, Neil W. Kowall, James J. Lah, Allan I. Levey, Andrew P. Lieberman, Oscar L. López, Wendy J. Mack, Daniel Marson, Frank Martiniuk, Deborah C. Mash, Eliezer Masliah, Wayne C. McCormick, Susan M. McCurry, Andrew McDavid, Ann C. McKee, Marsel Mesulam, Bruce L. Miller and 55 more - Nature Genetics 2011 cited by 2,014

  2. World‐Wide FINGERS Network: A global approach to risk reduction and prevention of dementia

    Authors: Miia Kivipelto, Francesca Mangialasche, Heather M. Snyder, Ricardo Allegri, Sandrine Andrieu, Hidenori Arai, Laura D. Baker, Sylvie Belleville, Henry Brodaty, Sônia Maria Dozzi Brucki, Ismael Luis Calandri, Paulo Caramelli, Christopher Chen, Howard Chertkow, Effie Chew, Seong Hye Choi, Neerja Chowdhary, Lucía Crivelli, Rafael de la Torre, Yifeng Du, Tarun Dua, Mark A. Espeland, Howard Feldman, Maris Hartmanis, Tobias Hartmann, Megan Heffernan, Christiani Jeyakumar Henry, Chang Hyung Hong, Krister Håkansson, Takeshi Iwatsubo, Jee Hyang Jeong, Gustavo Jimenez‐Maggiora, Edward H. Koo, Lenore J. Launer, Jenni Lehtisalo, Francisco Lopera, Pablo Martínez‐Lage, Ralph N. Martins, Lefkos Middleton, José Luís Molinuevo, Manuel Montero‐Odasso, So Young Moon, Kristal Morales‐Pérez, Ricardo Nitríni, Haakon B. Nygaard, Yoo K. Park, Markku Peltonen, Chengxuan Qiu, Yakeel T. Quiroz, Rema Raman, Naren P. Rao, Vijayalakshmi Ravindranath, Anna Rosenberg, Takashi Sakurai, Rosa María Salinas, Philip Scheltens, Gustavo Sevlever, Hilkka Soininen, Ana Luisa Sosa, Cláudia Kimie Suemoto, Mikel Tainta, Lina Velilla, Yongxiang Wang, Rachel A. Whitmer, Xin Xu, Lisa J. Bain, Alina Solomon, Tiia Ngandu, María C. Carrillo - Alzheimer s & Dementia 2020 cited by 521

  3. Probing sporadic and familial Alzheimer’s disease using induced pluripotent stem cells

    Authors: Mason A. Israel, Shauna H. Yuan, Cédric Bardy, Sol M. Reyna, Yangling Mu, Cheryl Herrera, Michael P. Hefferan, Sebastiaan van Gorp, Kristopher L. Nazor, Francesca S. Boscolo, Christian T. Carson, Louise C. Laurent, Martin Maršala, Fred H. Gage, Anne M. Remes, Edward H. Koo, Lawrence S.B. Goldstein - Nature 2012 cited by 1,275

  4. Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease

    Authors: Alan H. Nagahara, David A. Merrill, Giovanni Coppola, Shingo Tsukada, Brock E. Schroeder, Gideon M. Shaked, Ling Wang, Armin Blesch, Albert Kim, J. M. Conner, Edward Rockenstein, Moses V. Chao, Edward H. Koo, Daniel H. Geschwind, Eliezer Masliah, Andrea A. Chiba, Mark H. Tuszynski - Nature Medicine 2009 cited by 1,037

  5. Amyloid Precursor Protein Trafficking, Processing, and Function

    Authors: Gopal Thinakaran, Edward H. Koo - Journal of Biological Chemistry 2008 cited by 1,113

  6. Biology and pathophysiology of the amyloid precursor protein

    Authors: Hui Zheng, Edward H. Koo - Molecular Neurodegeneration 2011 cited by 346

  7. Evidence that NLRC4 inflammasome mediates apoptotic and pyroptotic microglial death following ischemic stroke

    Authors: Luting Poh, Sung-Wook Kang, Sang‐Ha Baik, Gavin Ng, David T. She, Priyanka Balaganapathy, S. Thameem Dheen, Tim Magnus, Mathias Gelderblom, Christopher G. Sobey, Edward H. Koo, David Y. Fann, Thiruma V. Arumugam - Brain Behavior and Immunity 2018 cited by 199

  8. Caspase Activation and Caspase-Mediated Cleavage of APP Is Associated with Amyloid β-Protein-Induced Synapse Loss in Alzheimer’s Disease

    Authors: Goonho Park, Hoang S. Nhan, Sheue-Houy Tyan, Yusuke Kawakatsu, Carolyn Zhang, Mario Navarro, Edward H. Koo - Cell Reports 2020 cited by 92

  9. Amyloid β-peptide is produced by cultured cells during normal metabolism

    Authors: Christian Haass, Michael G. Schlossmacher, Albert Y. Hung, Carmen Vigo‐Pelfrey, Angela Mellon, Beth L. Ostaszewski, Ivan Lieberburg, Edward H. Koo, Dale Schenk, David B. Teplow, Dennis J. Selkoe - Nature 1992 cited by 1,907

  10. The amyloid precursor protein: beyond amyloid.

    Authors: Hui Zheng, Edward H. Koo - Molecular Neurodegeneration 2006 cited by 393

  11. Modulation of amyloid β-protein clearance and Alzheimer’s disease susceptibility by the LDL receptor–related protein pathway

    Authors: David E. Kang, Claus U. Pietrzik, Larry Baum, Nathalie Chevallier, David E. Merriam, Maria Z. Kounnas, Steven L. Wagner, Juan C. Troncoso, Claudia H. Kawas, Robert Katzman, Edward H. Koo - Journal of Clinical Investigation 2000 cited by 354

  12. A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity

    Authors: Sascha Weggen, Jason L. Eriksen, Pritam Das, Sarah A. Sagi, Rong Wang, Claus U. Pietrzik, Kirk A. Findlay, Tawnya E. Smith, Michael P. Murphy, Thomas Bülter, David E. Kang, Numa R. Marquez-Sterling, Todd E. Golde, Edward H. Koo - Nature 2001 cited by 1,388

  13. The multifaceted nature of amyloid precursor protein and its proteolytic fragments: friends and foes

    Authors: Hoang S. Nhan, Karen Chiang, Edward H. Koo - Acta Neuropathologica 2014 cited by 240

  14. Early BDNF Treatment Ameliorates Cell Loss in the Entorhinal Cortex of APP Transgenic Mice

    Authors: Alan H. Nagahara, Michael Mateling, Imre Kovács, Ling Wang, Simone Eggert, Edward Rockenstein, Edward H. Koo, Eliezer Masliah, Mark H. Tuszynski - Journal of Neuroscience 2013 cited by 181

  15. Targeting of cell-surface β-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments

    Authors: Christian Haass, Edward H. Koo, Angela Mellon, Albert Y. Hung, Dennis J. Selkoe - Nature 1992 cited by 899

  16. Amyloid-β Peptides Interact with Plasma Proteins and Erythrocytes: Implications for Their Quantitation in Plasma

    Authors: Yu‐Min Kuo, Tyler A. Kokjohn, Walter M. Kalback, Dean C. Luehrs, Douglas Galasko, Nathalie Chevallier, Edward H. Koo, Mark R. Emmerling, Alex E. Roher - Biochemical and Biophysical Research Communications 2000 cited by 226

  17. Short Aβ peptides attenuate Aβ42 toxicity in vivo

    Authors: Brenda D. Moore, Jason Martin, Lorena de Mena, Jonatan Sánchez, Pedro E. Cruz, Carolina Ceballos‐Diaz, Thomas B. Ladd, Yong Ran, Yona Levites, Thomas Kukar, Justin Kurian, Robert McKenna, Edward H. Koo, David Borchelt, Christopher Janus, Diego E. Rincón-Limas, Pedro Fernández-Fúnez, Todd E. Golde - The Journal of Experimental Medicine 2017 cited by 87

  18. Amyloid Accumulation Drives Proteome-wide Alterations in Mouse Models of Alzheimer’s Disease-like Pathology

    Authors: Jeffrey N. Savas, Yizhi Wang, Laura A. DeNardo, Salvador Martínez‐Bartolomé, Daniel B. McClatchy, Timothy J. Hark, Natalie F. Shanks, Kira Cozzolino, Mathieu Lavallée‐Adam, Samuel N. Smukowski, Sung Kyu Park, Jeffery W. Kelly, Edward H. Koo, Terunaga Nakagawa, Eliezer Masliah, Anirvan Ghosh, John R. Yates - Cell Reports 2017 cited by 76

  19. Amyloid diseases: Abnormal protein aggregation in neurodegeneration

    Authors: Edward H. Koo, Peter T. Lansbury, Jeffery W. Kelly - National Academy of Sciences, Proceedings of the National Academy of Sciences 1999 cited by 697

  20. Visualizing APP and BACE-1 approximation in neurons yields insight into the amyloidogenic pathway

    Authors: Utpal Das, Lina Wang, Archan Ganguly, Junmi M. Saikia, Steven L. Wagner, Edward H. Koo, Subhojit Roy - Nature Neuroscience 2015 cited by 194

  21. γ-Secretase inhibitors and modulators

    Authors: Todd E. Golde, Edward H. Koo, Kevin M. Felsenstein, Barbara A. Osborne, Lucio Miele - Biochimica et Biophysica Acta (BBA) - Biomembranes 2013 cited by 277

  22. Amyloid precursor protein (APP) regulates synaptic structure and function

    Authors: Sheue-Houy Tyan, Ann Shih, Jessica J. Walsh, Hiroko Maruyama, Floyd Sarsoza, Lawrence Ku, Simone Eggert, Patrick R. Hof, Edward H. Koo, Dara L. Dickstein - Molecular and Cellular Neuroscience 2012 cited by 185

  23. SINgapore GERiatric intervention study to reduce physical frailty and cognitive decline (SINGER)–pilot: A feasibility study

    Authors: Kimberly Ann Chew, Xinyi Xu, Paula Siongco, Steven G Villaraza, April Ka Sin Phua, Zi Xuen Wong, Chooi Yu Chung, Ning Tang, Effie Chew, Christiani Jeyakumar Henry, Edward H. Koo, Christopher Chen - Alzheimer s & Dementia Translational Research & Clinical Interventions 2021 cited by 26

  24. Diverse compounds mimic Alzheimer disease–causing mutations by augmenting Aβ42 production

    Authors: Thomas Kukar, M. Paul Murphy, Jason L. Eriksen, Sarah A. Sagi, Sascha Weggen, Tawnya E. Smith, Thomas B. Ladd, Murad Ali Khan, Rajashaker Kache, J. David Beard, Mark Dodson, Sami L. Merit, Victor Ozols, Panos Z. Anastasiadis, Pritam Das, Abdul H. Fauq, Edward H. Koo, Todd E. Golde - Nature Medicine 2005 cited by 283