Eric F. Johnson
Active 1977–2024
- 104
- Papers
- 22,080
- Citations
- 77
- h-index
- 103
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology32.1%
- Medicine31.1%
- Pharmacology, Toxicology and Pharmaceutics19.9%
- Computer Science6.8%
- Chemistry2.5%
- Environmental Science2.3%
- Other5.3%
Topics
- Pharmacogenetics and Drug Metabolism8.7%
- Computational Drug Discovery Methods5.7%
- Drug Transport and Resistance Mechanisms4.1%
- PARP inhibition in cancer therapy3%
- Cell death mechanisms and regulation2.3%
- Peroxisome Proliferator-Activated Receptors2.2%
- Other74%
Coauthors
- Keith J. Griffin24
- C.D. Stout19
- Mei‐Hui Hsu14
- Yan Luo12
- Yan Shi11
- Vincent L. Giranda10
- Xuesong Liu10
- Jennifer J. Bouska9
- Thomas D. Penning9
- Amanda M. Olson8
- Cherrie K. Donawho8
- Saul H. Rosenberg8
- Jason K. Yano7
- G. Schoch6
- Judy L. Raucy6
- Michael R. Wester6
- Toby H. Richardson6
- Vered Klinghofer6
- Üzen Savas6
- Colin N.A. Palmer5
- Edward K. Han5
- Gui‐Dong Zhu5
- Ran Guan5
- Ursula Müller‐Eberhard5
All papers
- ABT-263: A Potent and Orally Bioavailable Bcl-2 Family Inhibitor
Authors: Christin Tse, Alexander R. Shoemaker, Jessica Adickes, Mark G. Anderson, Jun Chen, Sha Jin, Eric F. Johnson, Kennan C. Marsh, Michael J. Mitten, Paul Nimmer, Lisa Roberts, Stephen K. Tahir, Xiao Yu, Xiufen Yang, Haichao Zhang, Stephen W. Fesik, Saul H. Rosenberg, Steven W. Elmore - Cancer Research 2008 cited by 1,962
- ABC transporters: the power to change
Authors: Douglas C. Rees, Eric F. Johnson, Oded Lewinson - Nature Reviews Molecular Cell Biology 2009 cited by 1,446
- Navigating the kinome
Authors: James T. Metz, Eric F. Johnson, Niru B. Soni, Philip J. Merta, Lemma Kifle, Philip J. Hajduk - Nature Chemical Biology 2011 cited by 308
- PARP1 Trapping by PARP Inhibitors Drives Cytotoxicity in Both Cancer Cells and Healthy Bone Marrow
Authors: Todd A. Hopkins, William B. Ainsworth, Paul A. Ellis, Cherrie K. Donawho, Enrico L. DiGiammarino, Sanjay C. Panchal, Vivek C. Abraham, Mikkel A. Algire, Yan Shi, Amanda M. Olson, Eric F. Johnson, Julie L. Wilsbacher, David Maag - Molecular Cancer Research 2018 cited by 256
- Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer
Authors: Shikhar Sharma, Chi‐Yeh Chung, Sean Uryu, Jelena Petrovic, Joan Cao, Amanda J. Rickard, Nataliya Nady, S.E. Greasley, Eric F. Johnson, Oleg Brodsky, Showkhin Khan, Hui Wang, Zhenxiong Wang, Yong Zhang, Konstantinos Tsaparikos, Lei Chen, Anthony Mazurek, John D. Lapek, Pei‐Pei Kung, Scott C. Sutton, Paul Richardson, Eric C. Greenwald, Shinji Yamazaki, Rhys Jones, Karen A. Maegley, Patrick Bingham, Hieu Lam, Alexandra E. Stupple, Aileen Kamal, Anderly C. Chüeh, Anthony N. Cuzzupe, Benjamin J. Morrow, Bin Ren, Catalina Carrasco‐Pozo, Chin Wee Tan, Dharmesh D. Bhuva, Elizabeth Allan, Elliot Surgenor, François Vaillant, Havva Pehlivanoglu, Hendrik Falk, James R. Whittle, Janet Newman, Joseph Cursons, Judy P. Doherty, Karen L. White, Laura MacPherson, Mark Devlin, Matthew L. Dennis, Meghan Hattarki, Melanie de Silva, Michelle A. Camerino, Miriam Butler, Olan Dolezal, Patricia A. Pilling, Richard C. Foitzik, Paul A. Stupple, H. Rachel Lagiakos, Scott R. Walker, Soroor Hediyeh-zadeh, Stewart D. Nuttall, Sukhdeep K. Spall, Susan A. Charman, Theresa Connor, Thomas S. Peat, Vicky M. Avery, Ylva E. Bozikis, Yuqing Yang, Ming Zhang, Brendon J. Monahan, Anne K. Voss, Tim Thomas, Ian P. Street, Sarah‐Jane Dawson, Mark A. Dawson, Geoffrey J. Lindeman, Melissa J. Davis, Jane E. Visvader, Thomas A. Paul - Cell chemical biology 2023 cited by 69
- Selective MCL-1 inhibitor ABBV-467 is efficacious in tumor models but is associated with cardiac troponin increases in patients
Authors: Junichiro Yuda, Christine Will, Darren C. Phillips, Linu Abraham, Cory Alvey, Abraham Avigdor, Wayne R. Buck, Lauren M. Besenhofer, Erwin R. Boghaert, Dong Cheng, Dan Cojocari, Kelly Doyle, Terkel Hansen, Kevin Y. Huang, Eric F. Johnson, Andrew S. Judd, Russell A. Judge, J. Cory Kalvass, Aaron Kunzer, Lloyd T. Lam, Rachel Li, Ruth L. Martin, Anthony Mastracchio, Mike Mitten, Adam M. Petrich, Jin Wang, James E. Ward, Haichao Zhang, Xilu Wang, Johannes Wolff, Katherine M. Bell‐McGuinn, Andrew J. Souers - Communications Medicine 2023 cited by 66
- Mechanistic Dissection of PARP1 Trapping and the Impact on In Vivo Tolerability and Efficacy of PARP Inhibitors
Authors: Todd A. Hopkins, Yan Shi, Luis E. Rodrı́guez, Larry R. Solomon, Cherrie K. Donawho, Enrico L. DiGiammarino, Sanjay C. Panchal, Julie L. Wilsbacher, Wenqing Gao, Amanda M. Olson, DeAnne Stolarik, Donald J. Osterling, Eric F. Johnson, David Maag - Molecular Cancer Research 2015 cited by 267
- Design and Synthesis of Functionally Active 5-Amino-6-Aryl Pyrrolopyrimidine Inhibitors of Hematopoietic Progenitor Kinase 1
Authors: Rebecca A. Gallego, Louise Bernier, Hui Chen, Sujin Cho-Schultz, Loanne Chung, Michael R. Collins, Matthew Del Bel, Jeff Elleraas, Cinthia Costa Jones, Ciarán N. Cronin, Martin P. Edwards, Xu Fang, Timothy S. Fisher, Mingying He, Jacqui Hoffman, Ruiduan Huo, Mehran Jalaie, Eric F. Johnson, Ted W. Johnson, Robert S. Kania, Manfred Kraus, Jennifer Lafontaine, Phuong Le, Tongnan Liu, Michael Maestre, Jean Matthews, Michele McTigue, Nichol Miller, Qiming Mu, Xulong Qin, Shijian Ren, Paul Richardson, Allison Rohner, Neal W. Sach, Li Shao, Graham Smith, Ruirui Su, Bin Sun, Sergei Timofeevski, Phương Thu Trần, Shuiwang Wang, Wei Wang, Ru Zhou, JinJiang Zhu, Sajiv K. Nair - Journal of Medicinal Chemistry 2023 cited by 35
- ABT-888, an Orally Active Poly(ADP-Ribose) Polymerase Inhibitor that Potentiates DNA-Damaging Agents in Preclinical Tumor Models
Authors: Cherrie K. Donawho, Yan Luo, Yanping Luo, Thomas D. Penning, Joy Bauch, Jennifer J. Bouska, Velitchka Bontcheva-Diaz, Bryan F. Cox, Theodore L. DeWeese, Larry E. Dillehay, Debra C. Ferguson, Nayereh Ghoreishi‐Haack, David R. Grimm, Ran Guan, Edward K. Han, Rhonda R. Holley-Shanks, Boris Hristov, Kenneth B. Idler, Ken Jarvis, Eric F. Johnson, Lawrence Kleinberg, Vered Klinghofer, Loren Lasko, Xuesong Liu, Kennan C. Marsh, Thomas McGonigal, Jonathan A. Meulbroek, Amanda M. Olson, Joann P. Palma, Luis E. Rodrı́guez, Yan Shi, Jason Stavropoulos, Alan C. Tsurutani, Gui‐Dong Zhu, Saul H. Rosenberg, Vincent L. Giranda, David J. Frost - Clinical Cancer Research 2007 cited by 773
- The Structure of Human Microsomal Cytochrome P450 3A4 Determined by X-ray Crystallography to 2.05-Å Resolution
Authors: Jason K. Yano, Michael R. Wester, G. Schoch, Keith J. Griffin, C.D. Stout, Eric F. Johnson - Journal of Biological Chemistry 2004 cited by 699
- Discovery of the Poly(ADP-ribose) Polymerase (PARP) Inhibitor 2-[(R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide (ABT-888) for the Treatment of Cancer
Authors: Thomas D. Penning, Gui‐Dong Zhu, Viraj B. Gandhi, Jianchun Gong, Xuesong Liu, Yan Shi, Vered Klinghofer, Eric F. Johnson, Cherrie K. Donawho, David J. Frost, Velitchka Bontcheva-Diaz, Jennifer J. Bouska, Donald J. Osterling, Amanda M. Olson, Kennan C. Marsh, Yan Luo, Vincent L. Giranda - Journal of Medicinal Chemistry 2008 cited by 269
- Axitinib effectively inhibits BCR-ABL1(T315I) with a distinct binding conformation
Authors: Tea Pemovska, Eric F. Johnson, Mika Kontro, Gretchen A. Repasky, Jeffrey Chen, Peter A. Wells, Ciarán N. Cronin, Michele McTigue, Olli Kallioniemi, Kimmo Porkka, Brion W. Murray, Krister Wennerberg - Nature 2015 cited by 240
- Structural Characterization of Human Cytochrome P450 2C19
Authors: R. Leila Reynald, Stefaan Sansen, C.D. Stout, Eric F. Johnson - Journal of Biological Chemistry 2012 cited by 133
- Mirzotamab clezutoclax as monotherapy and in combination with taxane therapy in relapsed/refractory solid tumors: Dose expansion results.
Authors: Benedito A. Carneiro, Ruth Perets, Afshin Dowlati, Patricia LoRusso, Kan Yonemori, Lei He, Wijith Munasinghe, Behnam Noorani, Eric F. Johnson, Jon Zugazagoitia - Journal of Clinical Oncology 2023 cited by 18
- Aminopyridine-Based c-Jun N-Terminal Kinase Inhibitors with Cellular Activity and Minimal Cross-Kinase Activity
Authors: Bruce G. Szczepankiewicz, Christi Kosogof, Lissa T.J. Nelson, Gang Liu, Bo Liu, Hongyu Zhao, Michael D. Serby, Zhili Xin, Mei Liu, Rebecca J. Gum, Deanna L. Haasch, Sanyi Wang, Jill E. Clampit, Eric F. Johnson, Thomas Lübben, Michael A. Stashko, Edward T. Olejniczak, Chaohong Sun, Sarah A. Dorwin, Kristi Haskins, Cele Abad‐Zapatero, Elizabeth H. Fry, Charles W. Hutchins, Hing L. Sham, Cristina M. Rondinone, James M. Trevillyan - Journal of Medicinal Chemistry 2006 cited by 160
- Breaking tolerance to the natural human liver autoantigen cytochrome P450 2D6 by virus infection
Authors: Martin Holdener, Edith Hintermann, Monika Bayer, Antje Rhode, Evelyn Rodrigo, Gudrun Hintereder, Eric F. Johnson, Frank J. Gonzalez, Josef Pfeilschifter, Michael P. Manns, Matthias von Herrath, Urs Christen - The Journal of Experimental Medicine 2008 cited by 195
- Crystal Structure of CYP24A1, a Mitochondrial Cytochrome P450 Involved in Vitamin D Metabolism
Authors: Andrew J. Annalora, David B. Goodin, Wen‐Xu Hong, Qinghai Zhang, Eric F. Johnson, C.D. Stout - Journal of Molecular Biology 2009 cited by 177
- Multiple conformational states of the HPK1 kinase domain in complex with sunitinib reveal the structural changes accompanying HPK1 trans-regulation
Authors: Eric F. Johnson, Michele McTigue, Rebecca A. Gallego, Ted W. Johnson, Sergei Timofeevski, Michael Maestre, Timothy S. Fisher, Robert S. Kania, Sansana Sawasdikosol, Steven J. Burakoff, Ciarán N. Cronin - Journal of Biological Chemistry 2019 cited by 30
- The P450 Superfamily: Update on New Sequences, Gene Mapping, and Recommended Nomenclature
Authors: Daniel W. Nebert, David R. Nelson, Minor J. Coon, Ronald W. Estabrook, René Feyereisen, Yoshiaki Fujii‐Kuriyama, Frank J. Gonzalez, F. Peter Guengerich, I. C. Gunsalus, Eric F. Johnson, JOHN C. LOPER, Ryo Sato, Michael R. Waterman, David J. Waxman - DNA and Cell Biology 1991 cited by 1,095
- Adaptations for the Oxidation of Polycyclic Aromatic Hydrocarbons Exhibited by the Structure of Human P450 1A2
Authors: Stefaan Sansen, Jason K. Yano, R. Leila Reynald, G. Schoch, Keith J. Griffin, C.D. Stout, Eric F. Johnson - Journal of Biological Chemistry 2007 cited by 477
- Microbial ferric iron reductases
Authors: Imke Schröder, Eric F. Johnson, Simon de Vries - FEMS Microbiology Reviews 2003 cited by 320
- The High-Affinity E. coli Methionine ABC Transporter: Structure and Allosteric Regulation
Authors: Neena S. Kadaba, Jens T. Kaiser, Eric F. Johnson, Allen Lee, Douglas C. Rees - Science 2008 cited by 223
- Discovery of PF-07265028, A Selective Small Molecule Inhibitor of Hematopoietic Progenitor Kinase 1 (HPK1) for the Treatment of Cancer
Authors: Rebecca A. Gallego, Sujin Cho-Schultz, Matthew Del Bel, Anne‐Marie Dechert‐Schmitt, Joyann S. Donaldson, Mingying He, Mehran Jalaie, Rob Kania, Jean Matthews, Michele McTigue, Jamison B. Tuttle, Hud Risley, Dahui Zhou, Ru Zhou, Omar Ahmad, Louise Bernier, Simon Berritt, John Braganza, Zecheng Chen, Julie Cianfrogna, Michael R. Collins, Cinthia Costa Jones, Ciarán N. Cronin, Carl Davis, Klaus Dress, Martin P. Edwards, William Farrell, Scott P. France, Nicole Grable, Eric F. Johnson, Ted W. Johnson, Rhys Jones, Thomas Knauber, Jennifer Lafontaine, Richard P. Loach, Michael Maestre, Nichol Miller, Mark A. Moen, Sébastien Monfette, Peter Morse, Andrew R. Nager, Mark Niosi, Paul Richardson, Allison Rohner, Neal W. Sach, Sergei Timofeevski, Joseph W. Tucker, Beth C. Vetelino, Lei Zhang, Sajiv K. Nair - Journal of Medicinal Chemistry 2024 cited by 19
- Peroxisome Proliferator Activated Receptor-α Expression in Human Liver
Authors: Colin N.A. Palmer, Mei-H. Hsu, Keith J. Griffin, Judy L. Raucy, Eric F. Johnson - Molecular Pharmacology 1998 cited by 416
