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Frank Lyko

Active 1995–2025

105
Papers
21,592
Citations
78
h-index
102
i10-index

Citations

Citations per year for Frank Lyko1948: 1 citations1996: 1 citations1997: 4 citations1998: 19 citations1999: 10 citations2000: 28 citations2001: 57 citations2002: 61 citations2003: 40 citations2004: 33 citations2005: 46 citations2006: 66 citations2007: 96 citations2008: 146 citations2009: 172 citations2010: 211 citations2011: 306 citations2012: 246 citations2013: 299 citations2014: 282 citations2015: 257 citations2016: 261 citations2017: 249 citations2018: 266 citations2019: 742 citations2020: 841 citations2021: 954 citations2022: 759 citations2023: 606 citations2024: 806 citations2025: 404 citations2026: 6 citations1949–1995: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 2,290 citing papers, 25.9% of this breakdownChina: 1,364 citing papers, 15.4% of this breakdownGermany: 739 citing papers, 8.4% of this breakdownUnited Kingdom: 617 citing papers, 7% of this breakdownFrance: 350 citing papers, 4% of this breakdownItaly: 279 citing papers, 3.2% of this breakdownCanada: 243 citing papers, 2.7% of this breakdownSpain: 223 citing papers, 2.5% of this breakdownJapan: 218 citing papers, 2.5% of this breakdownAustralia: 204 citing papers, 2.3% of this breakdownIndia: 158 citing papers, 1.8% of this breakdownNetherlands: 138 citing papers, 1.6% of this breakdown
0%25.9%Other 22.7%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology72.4%
  • Medicine16.5%
  • Agricultural and Biological Sciences3.5%
  • Immunology and Microbiology3%
  • Neuroscience1.5%
  • Environmental Science1.2%
  • Other1.9%

Topics

  • Epigenetics and DNA Methylation14.9%
  • RNA modifications and cancer9.9%
  • Cancer-related gene regulation4.6%
  • Cancer-related molecular mechanisms research4.2%
  • RNA Research and Splicing2.9%
  • RNA and protein synthesis mechanisms2.9%
  • Other60.6%

Coauthors

All papers

Open in search
  1. The DNA methyltransferase family: a versatile toolkit for epigenetic regulation

    Authors: Frank Lyko - Nature Reviews Genetics 2017 cited by 1,498

  2. Single-cell transcriptomes of the human skin reveal age-related loss of fibroblast priming

    Authors: Llorenç Solé‐Boldo, Günter Raddatz, Sabrina Schütz, Jan‐Philipp Mallm, Karsten Rippe, Anke S. Lonsdorf, Manuel Rodríguez‐Paredes, Frank Lyko - Communications Biology 2020 cited by 535

  3. Dnmt2 mediates intergenerational transmission of paternally acquired metabolic disorders through sperm small non-coding RNAs

    Authors: Yunfang Zhang, Xudong Zhang, Junchao Shi, Francesca Tuorto, Xin Li, Yusheng Liu, Reinhard Liebers, Liwen Zhang, Yongcun Qu, Jingjing Qian, Maya Pahima, Ying Liu, Menghong Yan, Zhonghong Cao, Xiaohua Lei, Yujing Cao, Hongying Peng, Shichao Liu, Yue Wang, Huili Zheng, Rebekah Woolsey, David R. Quilici, Qiwei Zhai, Lei Li, Tong Zhou, Wei Yan, Frank Lyko, Ying Zhang, Qi Zhou, Enkui Duan, Qi Chen, Enkui Duan, Qi Chen - Nature Cell Biology 2018 cited by 494

  4. RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis

    Authors: Francesca Tuorto, Reinhard Liebers, Tanja Musch, Matthias Schaefer, Sarah Hofmann, Stefanie Kellner, Michaela Frye, Mark Helm, Georg Stoecklin, Frank Lyko - Nature Structural & Molecular Biology 2012 cited by 658

  5. Modes of action of the DNA methyltransferase inhibitors azacytidine and decitabine

    Authors: Carlo Stresemann, Frank Lyko - International Journal of Cancer 2008 cited by 948

  6. The microbiota programs DNA methylation to control intestinal homeostasis and inflammation

    Authors: Ihab Ansari, Günter Raddatz, Julian Gutekunst, Meshi Ridnik, Daphne Cohen, Monther Abu-Remaileh, Timur Tuganbaev, Hagit Shapiro, Eli Pikarsky, Eran Elinav, Frank Lyko, Yehudit Bergman - Nature Microbiology 2020 cited by 207

  7. RNA methylation by Dnmt2 protects transfer RNAs against stress-induced cleavage

    Authors: Matthias Schaefer, Tim Pollex, Katharina Hanna, Francesca Tuorto, Madeleine Meusburger, Mark Helm, Frank Lyko - Genes & Development 2010 cited by 773

  8. Epigenetic regulatory functions of DNA modifications: 5-methylcytosine and beyond

    Authors: Achim Breiling, Frank Lyko - Epigenetics & Chromatin 2015 cited by 366

  9. Queuosine‐modified tRNAs confer nutritional control of protein translation

    Authors: Francesca Tuorto, Carine Legrand, Cansu Cirzi, Giuseppina Federico, Reinhard Liebers, Martin Müller, Ann E. Ehrenhofer‐Murray, Gunnar Dittmar, Hermann‐Josef Gröne, Frank Lyko - The EMBO Journal 2018 cited by 205

  10. RNA cytosine methylation analysis by bisulfite sequencing

    Authors: Matthias Schaefer, Tim Pollex, K. Hanna, Frank Lyko - Nucleic Acids Research 2008 cited by 435

  11. 5-methylcytosine in RNA: detection, enzymatic formation and biological functions

    Authors: Yuri Motorin, Frank Lyko, Mark Helm - Nucleic Acids Research 2009 cited by 422

  12. The tRNA methyltransferase Dnmt2 is required for accurate polypeptide synthesis during haematopoiesis

    Authors: Francesca Tuorto, Friederike Herbst, Nader Alerasool, Sebastian Bender, Oliver Popp, Giuseppina Federico, Sonja Reitter, Reinhard Liebers, Georg Stoecklin, Hermann‐Josef Gröne, Gunnar Dittmar, Hanno Glimm, Frank Lyko - The EMBO Journal 2015 cited by 235

  13. Azacytidine Inhibits RNA Methylation at DNMT2 Target Sites in Human Cancer Cell Lines

    Authors: Matthias Schaefer, Sabine Hagemann, Katharina Hanna, Frank Lyko - Cancer Research 2009 cited by 219

  14. Functionally distinct cancer-associated fibroblast subpopulations establish a tumor promoting environment in squamous cell carcinoma

    Authors: Sabrina Schütz, Llorenç Solé‐Boldo, Carlota Lucena-Porcel, Jochen Hoffmann, Alexander Brobeil, Anke S. Lonsdorf, Manuel Rodríguez‐Paredes, Frank Lyko - Nature Communications 2023 cited by 50

  15. Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a

    Authors: Bernard Ramsahoye, Detlev Biniszkiewicz, Frank Lyko, Victoria H. Clark, Adrian Bird, Rudolf Jaenisch - National Academy of Sciences, Proceedings of the National Academy of Sciences 2000 cited by 974

  16. Loss of Tet Enzymes Compromises Proper Differentiation of Embryonic Stem Cells

    Authors: Meelad M. Dawlaty, Achim Breiling, Thuc T. Le, M. Inmaculada Barrasa, Günter Raddatz, Qing Gao, Benjamin E. Powell, Albert W. Cheng, Kym F. Faull, Frank Lyko, Rudolf Jaenisch - Developmental Cell 2014 cited by 348

  17. DNA Methyltransferase Inhibitors and the Development of Epigenetic Cancer Therapies

    Authors: Frank Lyko, Robert Brown - JNCI Journal of the National Cancer Institute 2005 cited by 508

  18. Epigenetic Reactivation of Tumor Suppressor Genes by a Novel Small-Molecule Inhibitor of Human DNA Methyltransferases

    Authors: Bodo Brueckner, Regine García Boy, Paweł Siedlecki, Tanja Musch, Hans‐Christian Kliem, Piotr Zielenkiewicz, Sándor Suhai, Manfred Wießler, Frank Lyko - Cancer Research 2005 cited by 542

  19. Queuosine‐tRNA promotes sex‐dependent learning and memory formation by maintaining codon‐biased translation elongation speed

    Authors: Cansu Cirzi, Julia Dyckow, Carine Legrand, Johanna Schott, Wei Guo, Daniel Pérez-Hernández, Miharu Hisaoka, Rosanna Parlato, Claudia Pitzer, Franciscus van der Hoeven, Gunnar Dittmar, Mark Helm, Georg Stoecklin, Lucas Schirmer, Frank Lyko, Francesca Tuorto - The EMBO Journal 2023 cited by 44

  20. Queuine links translational control in eukaryotes to a micronutrient from bacteria

    Authors: Martin Müller, Carine Legrand, Francesca Tuorto, Vincent P. Kelly, Yaser Atlasi, Frank Lyko, Ann E. Ehrenhofer‐Murray - Nucleic Acids Research 2019 cited by 99

  21. Epigenetic deregulation of lamina-associated domains in Hutchinson-Gilford progeria syndrome

    Authors: Florian Köhler, Felix Bormann, Günter Raddatz, Julian Gutekunst, Samuel Corless, Tanja Musch, Anke S. Lonsdorf, Sylvia Erhardt, Frank Lyko, Manuel Rodríguez‐Paredes - Genome Medicine 2020 cited by 78

  22. Combined Deficiency of Tet1 and Tet2 Causes Epigenetic Abnormalities but Is Compatible with Postnatal Development

    Authors: Meelad M. Dawlaty, Achim Breiling, Thuc T. Le, Günter Raddatz, M. Inmaculada Barrasa, Albert W. Cheng, Qing Gao, Benjamin E. Powell, Zhe Li, Mingjiang Xu, Kym F. Faull, Frank Lyko, Rudolf Jaenisch - Developmental Cell 2013 cited by 436

  23. Statistically robust methylation calling for whole-transcriptome bisulfite sequencing reveals distinct methylation patterns for mouse RNAs

    Authors: Carine Legrand, Francesca Tuorto, Mark Hartmann, Reinhard Liebers, Dominik Jacob, Mark Helm, Frank Lyko - Genome Research 2017 cited by 215

  24. Limited antibody specificity compromises epitranscriptomic analyses

    Authors: Mark Helm, Frank Lyko, Yuri Motorin - Nature Communications 2019 cited by 59