Frederick R. Maxfield
Active 1976–2025
- 141
- Papers
- 31,100
- Citations
- 103
- h-index
- 140
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology48.5%
- Medicine31.5%
- Immunology and Microbiology7%
- Neuroscience6.7%
- Materials Science1.8%
- Engineering1.2%
- Other3.3%
Topics
- Cellular transport and secretion6.6%
- Lipid Membrane Structure and Behavior5.7%
- Alzheimer's disease research and treatments2.8%
- Neuroinflammation and Neurodegeneration Mechanisms2.4%
- Cholesterol and Lipid Metabolism2%
- Erythrocyte Function and Pathophysiology1.9%
- Other78.6%
Coauthors
- Nina H. Pipalia12
- Ira Tabas11
- Sushmita Mukherjee11
- Lynda M. Pierini9
- Abigail S. Haka7
- Darrell J. Yamashiro7
- Ira Pastan7
- Mark C. Willingham7
- Satyajit Mayor7
- Timothy E. McGraw7
- Daniel Wüstner6
- Mingming Hao6
- Dana Cruz5
- Kenneth W. Dunn5
- Robert J. Eddy5
- Sharron X. Lin5
- Valéria C. Barbosa-Lorenzi5
- Amy Y. Huang4
- Charles Keith4
- David B. Iaea4
- Mousumi Mondal4
- Olaf Wiest4
- Paul Helquist4
- Xiaohui Zha4
All papers
- Cholesterol and matrisome pathways dysregulated in astrocytes and microglia
Authors: Julia TCW, Qian Lü, Nina H. Pipalia, Michael J. Chao, Shuang Liang, Yang Shi, Bharat R. Jain, Sarah Bertelsen, Manav Kapoor, Edoardo Marcora, Elizabeth Sikora, Elizabeth J. Andrews, Alessandra Cadete Martini, Celeste M. Karch, Elizabeth Head, David M. Holtzman, Bin Zhang, Minghui Wang, Frederick R. Maxfield, Wayne W. Poon, Alison Goate - Cell 2022 cited by 416
- Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing
Authors: Miguel Crespo, Eduardo Vilar, Su‐Yi Tsai, Kyle Chang, Sadaf Amin, Tara Srinivasan, Tuo Zhang, Nina H. Pipalia, Huanhuan Joyce Chen, Mavee Witherspoon, Miriam Gordillo, Jenny Xiang, Frederick R. Maxfield, Steven M. Lipkin, Todd Evans, Shuibing Chen - Nature Medicine 2017 cited by 387
- Metabolically Activated Adipose Tissue Macrophages Perform Detrimental and Beneficial Functions during Diet-Induced Obesity
Authors: Brittney R. Coats, Kelly Q. Schoenfelt, Valéria C. Barbosa-Lorenzi, Eduard Peris, Chang Cui, Alexandria Hoffman, Guolin Zhou, Sully Fernandez, Lijie Zhai, Ben A. Hall, Abigail S. Haka, Ajay M. Shah, Catherine A. Reardon, Matthew Brady, Christopher J. Rhodes, Frederick R. Maxfield, Lev Becker - Cell Reports 2017 cited by 282
- Mitochondrial Fission Promotes the Continued Clearance of Apoptotic Cells by Macrophages
Authors: Ying Wang, Manikandan Subramanian, Arif Yurdagul, Valéria C. Barbosa-Lorenzi, Bishuang Cai, Jaime de Juan‐Sanz, Timothy A. Ryan, Masatoshi Nomura, Frederick R. Maxfield, Ira Tabas - Cell 2017 cited by 367
- Role of cholesterol and lipid organization in disease
Authors: Frederick R. Maxfield, Ira Tabas - Nature 2005 cited by 1,285
- Endocytic recycling
Authors: Frederick R. Maxfield, Timothy E. McGraw - Nature Reviews Molecular Cell Biology 2004 cited by 1,683
- Cholesterol, the central lipid of mammalian cells
Authors: Frederick R. Maxfield, Gerrit van Meer - Current Opinion in Cell Biology 2010 cited by 414
- Microglial Cells Internalize Aggregates of the Alzheimer's Disease Amyloid β-Protein Via a Scavenger Receptor
Authors: Donata M. Paresce, Richik N. Ghosh, Frederick R. Maxfield - Neuron 1996 cited by 669
- Analysis of Cholesterol Trafficking with Fluorescent Probes
Authors: Frederick R. Maxfield, Daniel Wüstner - Methods in cell biology 2012 cited by 246
- Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models
Authors: Saravanan S. Karuppagounder, Ishraq Alim, Soah J. Khim, Megan W. Bourassa, Sama F. Sleiman, Roseleen F. John, Cyrille C. Thinnes, Tzu-Lan Yeh, Marina Demetriades, Sandra Neitemeier, Dana Cruz, Irina G. Gazaryan, David W. Killilea, Lewis B. Morgenstern, Guohua Xi, Richard F. Keep, Timothy Schallert, Ryan Tappero, Jian Zhong, Sunghee Cho, Frederick R. Maxfield, Theodore R. Holman, Carsten Culmsee, Guo‐Hua Fong, Yijing Su, Guo‐li Ming, Hongjun Song, John W. Cave, Christopher J. Schofield, Frederick Colbourne, Giovanni Coppola, Rajiv R. Ratan - Science Translational Medicine 2016 cited by 140
- Exocytosis of macrophage lysosomes leads to digestion of apoptotic adipocytes and foam cell formation
Authors: Abigail S. Haka, Valéria C. Barbosa-Lorenzi, Hyuek Jong Lee, Domenick J. Falcone, Clifford A. Hudis, Andrew J. Dannenberg, Frederick R. Maxfield - Journal of Lipid Research 2016 cited by 127
- The endocytic pathway in microglia during health, aging and Alzheimer’s disease
Authors: Santiago Solé‐Domènech, Dana Cruz, Estibaliz Capetillo‐Zarate, Frederick R. Maxfield - Ageing Research Reviews 2016 cited by 142
- Activation of Microglia Acidifies Lysosomes and Leads to Degradation of Alzheimer Amyloid Fibrils
Authors: Amitabha Majumdar, Dana Cruz, Nikiya Asamoah, Adina R. Buxbaum, István Sohár, Peter Lobel, Frederick R. Maxfield - Molecular Biology of the Cell 2007 cited by 287
- Endocytosis
Authors: Sushmita Mukherjee, Rahul Ghosh, Frederick R. Maxfield - Physiological Reviews 1997 cited by 1,287
- Uptake, Degradation, and Release of Fibrillar and Soluble Forms of Alzheimer's Amyloid β-Peptide by Microglial Cells
Authors: Haeyong Chung, Melanie Brazil, Thwe Thwe Soe, Frederick R. Maxfield - Journal of Biological Chemistry 1999 cited by 215
- A Murine Niemann-Pick C1 I1061T Knock-In Model Recapitulates the Pathological Features of the Most Prevalent Human Disease Allele
Authors: Maria Praggastis, Brett A. Tortelli, Jessie Zhang, Hideji Fujiwara, Rohini Sidhu, Anita Chacko, Zhouji Chen, Chan Chung, Andrew P. Lieberman, Jakub Sikora, Cristin Davidson, Steven U. Walkley, Nina H. Pipalia, Frederick R. Maxfield, Jean E. Schaffer, Daniel Ory - Journal of Neuroscience 2015 cited by 128
- A role of the frontotemporal lobar degeneration risk factor TMEM106B in myelination
Authors: Tuancheng Feng, Rory R Sheng, Santiago Solé‐Domènech, Mohammed Ullah, Xiaolai Zhou, Christina S. Mendoza, Laura Camila Martinez Enriquez, Isabel Iscol Katz, Daniel H. Paushter, Peter M. Sullivan, Xiaochun Wu, Frederick R. Maxfield, Fenghua Hu - Brain 2020 cited by 51
- Slow Degradation of Aggregates of the Alzheimer's Disease Amyloid β-Protein by Microglial Cells
Authors: Donata M. Paresce, Haeyong Chung, Frederick R. Maxfield - Journal of Biological Chemistry 1997 cited by 271
- Intracellular sterol dynamics
Authors: Bruno Mesmin, Frederick R. Maxfield - Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 2009 cited by 243
- Role of Endosomes and Lysosomes in Human Disease
Authors: Frederick R. Maxfield - Cold Spring Harbor Perspectives in Biology 2014 cited by 122
- Weak bases and ionophores rapidly and reversibly raise the pH of endocytic vesicles in cultured mouse fibroblasts.
Authors: Frederick R. Maxfield - The Journal of Cell Biology 1982 cited by 570
- MEMBRANE DOMAINS
Authors: Sushmita Mukherjee, Frederick R. Maxfield - Annual Review of Cell and Developmental Biology 2004 cited by 372
- Targeted recycling of PECAM from endothelial surface-connected compartments during diapedesis
Authors: Zahra Mamdouh, Xia Chen, Lynda M. Pierini, Frederick R. Maxfield, William A. Müller - Nature 2003 cited by 316
- A Carbon Nanotube Optical Reporter Maps Endolysosomal Lipid Flux
Authors: Prakrit V. Jena, Daniel Roxbury, Thomas Vito Galassi, Leila Akkari, Christopher P. Horoszko, David B. Iaea, Januka Budhathoki-Uprety, Nina H. Pipalia, Abigail S. Haka, Jackson D. Harvey, Jeetain Mittal, Frederick R. Maxfield, Johanna A. Joyce, Daniel A. Heller - ACS Nano 2017 cited by 127
