Harold A. Chapman
Active 1977–2024
- 117
- Papers
- 29,503
- Citations
- 92
- h-index
- 117
- i10-index
Citations
Citation sources
Countries
Institutions
- Harvard University1.7%
- Brigham and Women's Hospital1.2%
- University of California, San Francisco0.9%
- University of Michigan0.7%
- Inserm0.7%
- Yale University0.6%
- Other94.2%
Fields
- Medicine53.3%
- Biochemistry, Genetics and Molecular Biology31.1%
- Immunology and Microbiology10.9%
- Neuroscience1.2%
- Engineering0.7%
- Nursing0.5%
- Other2.3%
Topics
- Protease and Inhibitor Mechanisms4.9%
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis4.9%
- Neonatal Respiratory Health Research4.8%
- Cell Adhesion Molecules Research2.9%
- Chronic Obstructive Pulmonary Disease (COPD) Research2.2%
- Blood Coagulation and Thrombosis Mechanisms1.8%
- Other78.5%
Coauthors
- Guo‐Ping Shi27
- Ying Wei23
- Paul J. Wolters11
- Richard J. Riese11
- Alexis N. Brumwell10
- John J. Reilly9
- Hidde L. Ploegh8
- Kevin K. Kim8
- Michael A. Matthay8
- Dean Sheppard7
- Jaymin J. Kathiriya7
- Jóse A. Villadangos7
- Matthias C. Kugler7
- Claude Jourdan Le Saux6
- David Waltz6
- John S. Munger6
- Alexis Brumwell5
- Daniel I. Simon5
- Edwin K. Silverman5
- Frank E. Speizer5
- Galina K. Sukhova5
- Julia Jackson5
- O L Stone5
- Peter Libby5
All papers
- Alveolar regeneration through a Krt8+ transitional stem cell state that persists in human lung fibrosis
Authors: Maximilian Strunz, Lukas M. Simon, Meshal Ansari, Jaymin J. Kathiriya, Ilias Angelidis, Christoph H. Mayr, George Tsidiridis, Marius Lange, Laura F. Mattner, Min Yee, Paulina Ogar, Arunima Sengupta, I. V. Kukhtevich, Robert Schneider, Zhongming Zhao, Carola Voss, Tobias Stoeger, Jens Neumann, Anne Hilgendorff, Jürgen Behr, Michael A. O’Reilly, Mareike Lehmann, Gerald Burgstaller, Mélanie Königshoff, Harold A. Chapman, Fabian J. Theis, Herbert B. Schiller - Nature Communications 2020 cited by 748
- Collagen promotes anti-PD-1/PD-L1 resistance in cancer through LAIR1-dependent CD8+ T cell exhaustion
Authors: David H. Peng, B. Leticia Rodriguez, Lixia Diao, Limo Chen, Jing Wang, Lauren A. Byers, Ying Wei, Harold A. Chapman, Mitsuo Yamauchi, Carmen Behrens, Gabriela Raso, Luisa M. Solis Soto, Edwin R. Parra, Ignacio I. Wistuba, Jonathan M. Kurie, Don L. Gibbons - Nature Communications 2020 cited by 446
- TGF-β1 Signaling and Tissue Fibrosis
Authors: Kevin K. Kim, Dean Sheppard, Harold A. Chapman - Cold Spring Harbor Perspectives in Biology 2017 cited by 778
- Human distal airways contain a multipotent secretory cell that can regenerate alveoli
Authors: Maria C. Basil, Fabian L. Cardenas‐Diaz, Jaymin J. Kathiriya, Michael P. Morley, Justine Carl, Alexis N. Brumwell, Jeremy Katzen, Katherine J. Slovik, Apoorva Babu, Su Zhou, Madison M. Kremp, Katherine B. McCauley, Shanru Li, Joseph D. Planer, Shah S. Hussain, Xiaoming Liu, Rebecca Windmueller, Yun Ying, Kathleen M. Stewart, M. Oyster, Jason D. Christie, Joshua M. Diamond, John F. Engelhardt, Edward Cantu, Steven M. Rowe, Darrell N. Kotton, Harold A. Chapman, Edward E. Morrisey - Nature 2022 cited by 319
- Lineage-negative progenitors mobilize to regenerate lung epithelium after major injury
Authors: Andrew E. Vaughan, Alexis N. Brumwell, Ying Xi, Jeffrey E. Gotts, Douglas Brownfield, Barbara Treutlein, Kevin S. W. Tan, Victor M. Tan, Feng Chun Liu, Mark R. Looney, Michael A. Matthay, Jason R. Rock, Harold A. Chapman - Nature 2014 cited by 725
- Human alveolar type 2 epithelium transdifferentiates into metaplastic KRT5+ basal cells
Authors: Jaymin J. Kathiriya, Chaoqun Wang, Minqi Zhou, Alexis Brumwell, Monica Cassandras, Claude Jourdan Le Saux, Max Cohen, Kostantinos-Dionysios Alysandratos, Bruce Wang, Paul J. Wolters, Michael A. Matthay, Darrell N. Kotton, Harold A. Chapman, Tien Peng - Nature Cell Biology 2021 cited by 268
- Repair and Regeneration of the Respiratory System: Complexity, Plasticity, and Mechanisms of Lung Stem Cell Function
Authors: Brigid L.M. Hogan, Christina E. Barkauskas, Harold A. Chapman, Jonathan A. Epstein, Rajan Jain, Connie C. W. Hsia, Laura E. Niklason, Elizabeth Calle, Andrew V. Le, Scott H. Randell, Jason R. Rock, Melinda Snitow, Matthew F. Krummel, Barry R. Stripp, Thiennu H. Vu, Eric S. White, Jeffrey A. Whitsett, Edward E. Morrisey - Cell stem cell 2014 cited by 922
- Yap/Taz regulate alveolar regeneration and resolution of lung inflammation
Authors: Ryan LaCanna, Daniela Liccardo, Peggy Zhang, Lauren Tragesser, Yan Wang, Tongtong Cao, Harold A. Chapman, Edward E. Morrisey, Hao Shen, Walter J. Koch, Beata Kośmider, Marla R. Wolfson, Ying Tian - Journal of Clinical Investigation 2019 cited by 308
- Distinct Airway Epithelial Stem Cells Hide among Club Cells but Mobilize to Promote Alveolar Regeneration
Authors: Jaymin J. Kathiriya, Alexis N. Brumwell, Julia Jackson, Xiaodan Tang, Harold A. Chapman - Cell stem cell 2020 cited by 256
- Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix
Authors: Kevin K. Kim, Matthias C. Kugler, Paul J. Wolters, Liliane Robillard, Michael G. Galvez, Alexis N. Brumwell, Dean Sheppard, Harold A. Chapman - National Academy of Sciences, Proceedings of the National Academy of Sciences 2006 cited by 1,238
- Local lung hypoxia determines epithelial fate decisions during alveolar regeneration
Authors: Ying Xi, Thomas Kim, Alexis N. Brumwell, Ian Driver, Ying Wei, Victor M. Tan, Julia Jackson, Jianming Xu, Dong-Kee Lee, Jeffrey E. Gotts, Michael A. Matthay, John M. Shannon, Harold A. Chapman, Andrew E. Vaughan - Nature Cell Biology 2017 cited by 286
- Extracellular matrix in lung development, homeostasis and disease
Authors: Yong Zhou, Jeffrey C. Horowitz, Alexandra Naba, Namasivayam Ambalavanan, Kamran Atabai, Jenna L. Balestrini, Peter B. Bitterman, Richard Corley, Bi‐Sen Ding, Adam J. Engler, Kirk C. Hansen, James S. Hagood, Farrah Kheradmand, Qing S. Lin, Enid Neptune, Laura E. Niklason, Luis A. Ortiz, William C. Parks, Daniel J. Tschumperlin, Eric S. White, Harold A. Chapman, Victor J. Thannickal - Matrix Biology 2018 cited by 291
- Secretion of leukotrienes by senescent lung fibroblasts promotes pulmonary fibrosis
Authors: Christopher D. Wiley, Alexis N. Brumwell, Sonnet S. Davis, Julia Jackson, Alexis Valdovinos, Cheresa Calhoun, Fatouma Alimirah, Carlos A. Castellanos, Richard Ruan, Ying Wei, Harold A. Chapman, Arvind Ramanathan, Judith Campisi, Claude Jourdan Le Saux - JCI Insight 2019 cited by 128
- Fibroblast-specific inhibition of TGF-β1 signaling attenuates lung and tumor fibrosis
Authors: Ying Wei, Thomas J. Kim, David H. Peng, Dana Duan, Don L. Gibbons, Mitsuo Yamauchi, Julia Jackson, Claude Jourdan Le Saux, Cheresa Calhoun, Jay I. Peters, Rik Derynck, Bradley J. Backes, Harold A. Chapman - Journal of Clinical Investigation 2017 cited by 185
- Gli1+ mesenchymal stromal cells form a pathological niche to promote airway progenitor metaplasia in the fibrotic lung
Authors: Monica Cassandras, Chaoqun Wang, Jaymin J. Kathiriya, Tatsuya Tsukui, Peri Matatia, Michael A. Matthay, Paul J. Wolters, Ari B. Molofsky, Dean Sheppard, Harold A. Chapman, Tien Peng - Nature Cell Biology 2020 cited by 105
- The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor
Authors: Sarah E. Ewald, Bettina L. Lee, Laura Lau, Katherine E. Wickliffe, Guo‐Ping Shi, Harold A. Chapman, Gregory M. Barton - Nature 2008 cited by 605
- Integrin α6β4 identifies an adult distal lung epithelial population with regenerative potential in mice
Authors: Harold A. Chapman, Xiaopeng Li, Jonathan P. Alexander, Alexis Brumwell, Walter Lorizio, Kevin S. W. Tan, Arnoud Sonnenberg, Ying Wei, Thiennu H. Vu - Journal of Clinical Investigation 2011 cited by 421
- Epithelial-Mesenchymal Interactions in Pulmonary Fibrosis
Authors: Harold A. Chapman - Annual Review of Physiology 2011 cited by 415
- A fibroblast-dependent TGF-β1/sFRP2 noncanonical Wnt signaling axis promotes epithelial metaplasia in idiopathic pulmonary fibrosis
Authors: Max Cohen, Alexis N. Brumwell, Tsung Che Ho, Kiana Garakani, Genevieve Montas, Darren Leong, Vivianne W. Ding, Jeffrey A. Golden, Binh N. Trinh, David M. Jablons, Michael A. Matthay, Kirk D. Jones, Paul J. Wolters, Ying Wei, Harold A. Chapman, Claude Jourdan Le Saux - Journal of Clinical Investigation 2024 cited by 68
- Future Directions in Idiopathic Pulmonary Fibrosis Research. An NHLBI Workshop Report
Authors: Timothy S. Blackwell, Andrew M. Tager, Zea Borok, Bethany B. Moore, David A. Schwartz, Kevin J. Anstrom, Ziv Bar‐Joseph, Peter B. Bitterman, Michael R. Blackburn, William Bradford, Kevin K. Brown, Harold A. Chapman, Harold R. Collard, Gregory P. Cosgrove, Robin R. Deterding, Ramona L. Doyle, Kevin R. Flaherty, Christine Kim Garcia, James S. Hagood, Craig A. Henke, Erica L. Herzog, Cory M. Hogaboam, Jeffrey C. Horowitz, Talmadge E. King, James E. Loyd, William E. Lawson, Clay B. Marsh, Paul W. Noble, Imre Noth, Dean Sheppard, Julie Olsson, Luis A. Ortiz, Thomas G. O’Riordan, Tim D. Oury, Ganesh Raghu, Jesse Roman, Patricia J. Sime, Thomas H. Sisson, Daniel J. Tschumperlin, Shelia M. Violette, Timothy E. Weaver, Rebecca G. Wells, Eric S. White, Naftali Kaminski, Fernando J. Martínez, Thomas A. Wynn, Victor J. Thannickal, Jerry P. Eu - American Journal of Respiratory and Critical Care Medicine 2013 cited by 247
- Expression of the elastolytic cathepsins S and K in human atheroma and regulation of their production in smooth muscle cells.
Authors: Galina K. Sukhova, Guo‐Ping Shi, Daniel I. Simon, Harold A. Chapman, Peter Libby - Journal of Clinical Investigation 1998 cited by 672
- Hypoxia-Inducible Factor 1α Signaling Promotes Repair of the Alveolar Epithelium after Acute Lung Injury
Authors: Jazalle McClendon, Nicole L. Jansing, Elizabeth F. Redente, Aneta Gandjeva, Yoko Ito, Sean P. Colgan, Aftab Ahmad, David W. H. Riches, Harold A. Chapman, Robert J. Mason, Rubin M. Tuder, Rachel L. Zemans - American Journal Of Pathology 2017 cited by 94
- EMERGING ROLES FOR CYSTEINE PROTEASES IN HUMAN BIOLOGY
Authors: Harold A. Chapman, Richard J. Riese, Guo‐Ping Shi - Annual Review of Physiology 1997 cited by 785
- Suppression of Tumor Invasion and Metastasis by Concurrent Inhibition of c-Met and VEGF Signaling in Pancreatic Neuroendocrine Tumors
Authors: Barbara Sennino, Toshina Ishiguro‐Oonuma, Ying Wei, Ryan M. Naylor, Casey W. Williamson, Vikash Bhagwandin, Sébastien P. Tabruyn, Weon‐Kyoo You, Harold A. Chapman, James G. Christensen, Dana T. Aftab, Donald M. McDonald - Cancer Discovery 2012 cited by 417
