Hélène Blanché

Active 1994–2025

Also published as
Hélène Blanche
62
Papers
17,979
Citations
46
h-index
56
i10-index

Citations

Citations per year for Hélène Blanché1991: 1 citations1994: 1 citations1995: 8 citations1996: 15 citations1997: 20 citations1998: 38 citations1999: 42 citations2000: 52 citations2001: 47 citations2002: 33 citations2003: 37 citations2004: 50 citations2005: 21 citations2006: 39 citations2007: 27 citations2008: 99 citations2009: 139 citations2010: 210 citations2011: 188 citations2012: 196 citations2013: 171 citations2014: 224 citations2015: 193 citations2016: 234 citations2017: 226 citations2018: 234 citations2019: 497 citations2020: 560 citations2021: 548 citations2022: 444 citations2023: 334 citations2024: 436 citations2025: 188 citations2026: 5 citations1992–1993: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 2,668 citing papers, 22.6% of this breakdownUnited Kingdom: 1,108 citing papers, 9.4% of this breakdownGermany: 770 citing papers, 6.5% of this breakdownChina: 690 citing papers, 5.8% of this breakdownFrance: 624 citing papers, 5.3% of this breakdownItaly: 495 citing papers, 4.2% of this breakdownNetherlands: 404 citing papers, 3.4% of this breakdownCanada: 397 citing papers, 3.4% of this breakdownSpain: 391 citing papers, 3.3% of this breakdownAustralia: 383 citing papers, 3.2% of this breakdownSweden: 277 citing papers, 2.3% of this breakdownDenmark: 248 citing papers, 2.1% of this breakdown
0%22.6%Other 28.5%

Fields

  • Biochemistry, Genetics and Molecular Biology44.4%
  • Medicine42.7%
  • Neuroscience5.5%
  • Immunology and Microbiology1.5%
  • Social Sciences1.3%
  • Agricultural and Biological Sciences0.8%
  • Other3.8%

Topics

  • Alzheimer's disease research and treatments4.8%
  • Genetic Associations and Epidemiology4.1%
  • Retinal Diseases and Treatments3.2%
  • Neuroinflammation and Neurodegeneration Mechanisms2.4%
  • Forensic and Genetic Research2.1%
  • Genetics, Aging, and Longevity in Model Organisms2%
  • Other81.4%

Coauthors

All papers

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  1. A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Xiaowei Zhan, Alan Kwong, Alexis Boleda, Matthew Brooks, Linn Gieser, Rinki Ratnapriya, Kari Branham, Johanna R. Foerster, John R. Heckenlively, Mohammad Othman, Brendan J. Vote, Helena H. Liang, Emmanuelle Souzeau, Ian L. McAllister, Timothy Isaacs, Janette M. Hall, Stewart Lake, David A. Mackey, Ian J. Constable, Jamie E. Craig, Terrie Kitchner, Zhenglin Yang, Zhiguang Su, Hongrong Luo, Daniel Chen, Hong Ouyang, Ken Flagg, Danni Lin, Guanping Mao, Henry Ferreyra, Klaus Stark, Claudia N. von Strachwitz, Armin Wolf, Caroline Brandl, Guenther Rudolph, Matthias Olden, Margaux A. Morrison, Denise J. Morgan, Matthew Schu, Jeeyun Ahn, Giuliana Silvestri, Evangelia E. Tsironi, Kyu Hyung Park, Lindsay A. Farrer, Anton Orlin, Alexander J. Brucker, Mingyao Li, Christine A. Curcio, Saddek Mohand‐Saïd, José‐Alain Sahel, Isabelle Audo, Mustapha Benchaboune, Angela J. Cree, Christina Rennie, Srinivas Goverdhan, Michelle Grunin, Shira Hagbi-Levi, Peter A. Campochiaro, Nicholas Katsanis, Frank G. Holz, Frédéric Blond, Hélène Blanché, Jean‐François Deleuze, Robert P. Igo, Barbara Truitt, Neal S. Peachey, Stacy M. Meuer, Chelsea E. Myers, Emily Moore, Ronald Klein and 62 more - Nature Genetics 2015 cited by 1,620

  2. Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Paolo Bosco, Michelangelo Mancuso, Francesco Panza, Benedetta Nacmias, Paola Bossù, Paola Piccardi, Giorgio Annoni, Davide Seripa, Daniela Galimberti, Didier Hannequin, Federico Licastro, Hilkka Soininen, Karen Ritchie, Hélène Blanché, Jean‐François Dartigues, Christophe Tzourio, Marta Gut, Christine Van Broeckhoven, Annick Alpérovitch, Mark Lathrop, Philippe Amouyel - Nature Genetics 2009 cited by 2,271

  3. The complete genome sequence of a Neanderthal from the Altai Mountains

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Howard M. Cann, Jacob O. Kitzman, Jay Shendure, Evan E. Eichler, Ed S. Lein, Trygve E. Bakken, Liubov V. Golovanova, Vladimir B. Doronichev, M.V. Shunkov, А. П. Деревянко, Bence Viola, Montgomery Slatkin, David Reich, Janet Kelso, Svante Pääbo - Nature 2013 cited by 2,442

  4. A meta-analysis of genome-wide association studies identifies multiple longevity genes

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Jean‐François Deleuze, Rachel Duncan, Jessica D. Faul, Claudio Franceschi, Pilar Galán, Vilmundur Guðnason, Tamara B. Harris, Martijn Huisman, Mikko Hurme, Carol Jagger, Iris E. Jansen, Marja Jylhä, Mika Kähönen, David Karasik, Sharon L. R. Kardia, Andrew Kingston, Thomas B. L. Kirkwood, Lenore J. Launer, Terho Lehtimäki, Wolfgang Lieb, Leo‐Pekka Lyytikäinen, Carmen Martín-Ruiz, Junxia Min, Almut Nebel, Anne B. Newman, Chao Nie, Ellen A. Nøhr, Eric Orwoll, Thomas T. Perls, Michael A. Province, Bruce M. Psaty, Olli Raitakari, Marcel Reinders, Jean‐Marie Robine, Jerome I. Rotter, Paola Sebastiani, Jennifer A. Smith, Thorkild I. A. Sørensen, Kent D. Taylor, André G. Uitterlinden, Wiesje M. van der Flier, Sven J. van der Lee, Cornelia M. van Duijn, Diana van Heemst, James W. Vaupel, David R. Weir, Kenny Ye, Yi Zeng, Wanlin Zheng, Henne Holstege, Douglas P. Kiel, Kathryn L. Lunetta, P. Eline Slagboom, Joanne M. Murabito - Nature Communications 2019 cited by 404

  5. Insights into human genetic variation and population history from 929 diverse genomes

    Authors: , , , , , , , , , , , , , , , , , , , , - Science 2019 cited by 1,104

  6. Genome-wide association analysis in dilated cardiomyopathy reveals two new players in systolic heart failure on chromosomes 3p25.1 and 22q11.23

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Patrick Lacolley, Xavier Jouven, Jeanette Erdmann, Stefan Blankenberg, Thomas Wichter, Volker Ruppert, Luigi Tavazzi, Olivier Dubourg, Gérard Roizès, Richard Dorent, Pascal de Groote, Laurent Fauchier, Jean‐Noël Trochu, Jean‐François Aupetit, Zofia T. Bilińska, Marine Germain, Uwe Völker, Daiane Hemerich, Ibticem Raji, Delphine Bacq‐Daian, Carole Proust, Paloma Remior, Manuel Gómez‐Bueno, Kristin Lehnert, Renée G. C. Maas, Robert Olaso, Ganapathi Varma Saripella, Stephan B. Felix, Steven McGinn, Laëtitia Duboscq-Bidot, Alain van Mil, Céline Besse, Vincent Fontaine, Hélène Blanché, Flavie Ader, Brendan J. Keating, Angélique Curjol, Anne Boland, Michel Komajda, François Cambien, Jean‐François Deleuze, Marcus Dörr, Folkert W. Asselbergs, Eric Villard, David‐Alexandre Trégouët, Philippe Charron - European Heart Journal 2021 cited by 90

  7. A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Sophie Gad, Stéphane Richard, Jérôme Couturier, Bin Tean Teh, Paola Ghiorzo, Lorenza Pastorino, Susana Puig, Célia Bádenas, Håkan Olsson, Christian Ingvar, Etienne Rouleau, Rosette Lidereau, Philippe Bahadoran, Philippe Vielh, Eve Corda, Hélène Blanché, Diana Zélénika, Pilar Galán, The French Familial Melanoma Study Group, F. Aubin, Bertrand Bachollet, Céline Becuwe, Pascaline Berthet, Yves Jean Bignon, Valérie Bonadona, Jean‐Louis Bonafé, Marie‐Noëlle Bonnet‐Dupeyron, F. Cambazard, J. Chevrant‐Breton, Isabelle Coupier, S. Dalac, Liliane Demange, M. D’Incan, Catherine Dugast, Laurence Faivre, Lynda Vincent-Fétita, Marion Gauthier-Villars, Brigitte Gilbert, Florent Grange, Jean‐Jacques Grob, Philippe Humbert, Nicolas Janin, Pascal Joly, Delphine Kérob, Christine Lasset, Dominique Leroux, J. Levang, Jean‐Marc Limacher, C. Bulaï Livideanu, Michel Longy, Alain Lortholary, Dominique Stoppa-Lyonnet, Sandrine Mansard, L Mansuy, Karine Marrou, Christine Matéus, Christine Maugard, Nicolás Meyer, Catherine Noguès, P Souteyrand, Laurence Venat‐Bouvet, Hélène Zattara, Valérie Chaudru, Gilbert Lenoir, Mark Lathrop, Irwin Davidson, Marie-Françoise Avril, Florence Démenais, Robert Ballotti, Brigitte Bressac–de Paillerets - Nature 2011 cited by 522

  8. Association of Smoking, Alcohol Consumption, Blood Pressure, Body Mass Index, and Glycemic Risk Factors With Age-Related Macular Degeneration

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Yara Lechanteur, Robyn H. Guymer, Matthew P Johnson, Yingda Jiang, Chloë M. Stanton, Gabriëlle H.S. Buitendijk, Xiaowei Zhan, Alan Kwong, Alexis Boleda, Matthew Brooks, Linn Gieser, Rinki Ratnapriya, Kari Branham, Johanna R. Foerster, John R. Heckenlively, Mohammad Othman, Brendan J. Vote, Helena H. Liang, Emmanuelle Souzeau, Ian L. McAllister, Timothy Isaacs, Janette M. Hall, Stewart Lake, David A. Mackey, Ian J. Constable, Jamie E. Craig, Terrie Kitchner, Zhenglin Yang, Zhiguang Su, Hongrong Luo, Daniel Chen, Hong Ouyang, Ken Flagg, Danni Lin, Guanping Mao, Henry Ferreyra, Klaus Stark, Claudia N. von Strachwitz, Armin Wolf, Caroline Brandl, Guenther Rudolph, Matthias Olden, Margaux A. Morrison, Denise J. Morgan, Matthew Schu, Jeeyun Ahn, Giuliana Silvestri, Evangelia E. Tsironi, Kyu Hyung Park, Lindsay A. Farrer, Anton Orlin, Alexander J. Brucker, Mingyao Li, Christine A. Curcio, Saddek Mohand‐Saïd, José‐Alain Sahel, Isabelle Audo, Mustapha Benchaboune, Angela J. Cree, Christina Rennie, Srinivas Goverdhan, Michelle Grunin, Shira Hagbi-Levi, Peter A. Campochiaro, Nicholas Katsanis, Frank G. Holz, Frédéric Blond, Hélène Blanché, Jean‐François Deleuze, Robert P. Igo and 68 more - JAMA Ophthalmology 2021 cited by 93

  9. Association of Self-reported COVID-19 Infection and SARS-CoV-2 Serology Test Results With Persistent Physical Symptoms Among French Adults During the COVID-19 Pandemic

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Alpha Amadou Barry, Nadège Senina, Gianluca Severi, Julien Allègre, Fabien Szabo de Edelenyi, Nathalie Druesne‐Pecollo, Younes Esseddik, Serge Hercberg, Mathilde Touvier, Marie-Aline Charles, Pierre‐Yves Ancel, Valérie Benhammou, Anass Ritmi, Laetitia Marchand‐Martin, Cécile Zaros, Elodie Lordmi, Adriana Candea, Sophie de Visme, Thierry Siméon, Xavier Thierry, Bertrand Geay, Marie‐Noëlle Dufourg, Karen Milcent, Delphine Rahib, Nathalie Lydié, Clovis Lusivika‐Nzinga, Grégory Pannetier, Nathanaël Lapidus, Isabelle Goderel, Céline Dorival, Jérôme Nicol, Fabrice Carrat, Cindy J. Lai, Liza Belhadji, Hélène Espérou, Sandrine Couffin-Cadièrgues, Jean‐Marie Gagliolo, Hélène Blanché, Jean-Marc Sébaoun, Jean-Christophe Beaudoin, Lætitia Gressin, Valérie Morel, Ouissam Ouili, Jean‐François Deleuze, Läétitia Ninove, Stéphane Priet, Paola Mariela Saba Villarroel, Toscane Fourié, Souand Mohamed Ali, Abdenour Amroun, Morgan Seston, Nazlı Ayhan, Boris Pastorino, Xavier de Lamballerie - JAMA Internal Medicine 2021 cited by 273

  10. A transcriptome-wide association study based on 27 tissues identifies 106 genes potentially relevant for disease pathology in age-related macular degeneration

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Yingda Jiang, Chloë M. Stanton, Gabriëlle H.S. Buitendijk, Xiaowei Zhan, Alan Kwong, Alexis Boleda, Matthew Brooks, Linn Gieser, Rinki Ratnapriya, Kari Branham, Johanna R. Foerster, John R. Heckenlively, Mohammad Othman, Brendan J. Vote, Helena H. Liang, Emmanuelle Souzeau, Ian L. McAllister, Timothy Isaacs, Janette M. Hall, Stewart Lake, David A. Mackey, Ian J. Constable, Jamie E. Craig, Terrie Kitchner, Zhenglin Yang, Zhiguang Su, Hongrong Luo, Daniel Chen, Hong Ouyang, Ken Flagg, Danni Lin, Guanping Mao, Henry Ferreyra, Klaus Stark, Claudia N. von Strachwitz, Armin Wolf, Caroline Brandl, Guenther Rudolph, Matthias Olden, Margaux A. Morrison, Denise J. Morgan, Matthew Schu, Jeeyun Ahn, Giuliana Silvestri, Evangelia E. Tsironi, Kyu Hyung Park, Lindsay A. Farrer, Anton Orlin, Alexander J. Brucker, Mingyao Li, Christine A. Curcio, Saddek Mohand‐Saïd, José‐Alain Sahel, Isabelle Audo, Mustapha Benchaboune, Angela J. Cree, Christina Rennie, Srinivas Goverdhan, Michelle Grunin, Shira Hagbi-Levi, Peter A. Campochiaro, Nicholas Katsanis, Frank G. Holz, Frédéric Blond, Hélène Blanché, Jean‐François Deleuze, Robert P. Igo, Barbara Truitt, Neal S. Peachey, Stacy M. Meuer and 67 more - Scientific Reports 2020 cited by 63

  11. A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Françoise Clavel‐Chapelon, Paolo Vineis, H. Bas Bueno‐de‐Mesquita, Eiliv Lund, Carmen Martı́nez, Sheila Bingham, Torgny Rasmuson, Pierre Hainaut, Elio Ríboli, Wolfgang Ahrens, Simone Benhamou, Παγώνα Λάγιου, Dimitrios Trichopoulos, Ivana Holcátová, Franco Merletti, Kristina Kjærheim, Antonio Agudo, Gary J. Macfarlane, Renato Talamini, Lorenzo Simonato, Ray Lowry, David I. Conway, Ariana Znaor, Claire M. Healy, Diana Zélénika, Anne Boland, Marc Délepine, Mario Foglio, Doris Lechner, Fumihiko Matsuda, Hélène Blanché, Marta Gut, Simon Heath, Mark Lathrop, Paul Brennan - Nature 2008 cited by 1,291

  12. Adaptive archaic introgression of copy number variants and the discovery of previously unknown human genes

    Authors: , , , , , , , , , , , , , , , , , , , - Science 2019 cited by 94

  13. Association of FOXO3A variation with human longevity confirmed in German centenarians

    Authors: , , , , , , , - National Academy of Sciences, Proceedings of the National Academy of Sciences 2009 cited by 571

  14. Variation in genomic landscape of clear cell renal cell carcinoma across Europe

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Jiří Zavadil, Jing Su, Ivana Holcátová, A. Brisuda, Давид Заридзе, Anush Moukeria, Lenka Foretová, Marie Navrátilová, Dana Mateș, Viorel Jinga, Artem V. Artemov, Artem Nedoluzhko, Alexander M. Mazur, Sergey Rastorguev, Eugenia Boulygina, Simon Heath, Marta Gut, Marie‐Thérèse Bihoreau, Doris Lechner, Mario Foglio, Marta Gut, K. G. Skryabin, Egor Prokhortchouk, Anne Cambon‐Thomsen, Johan Rung, Guillaume Bourque, Paul Brennan, Jörg Tost, Rosamonde E. Banks, Alvis Brāzma, G.M. Lathrop - Nature Communications 2014 cited by 200

  15. Genome-wide association study identifies multiple risk loci for renal cell carcinoma

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Lenka Foretová, Ivana Holcátová, Vladimí­r Janout, Dana Mateș, Anush Mukeriya, Ștefan Rașcu, Давид Заридзе, Vladimír Bencko, Cezary Cybulski, Eleonóra Fabiánová, Viorel Jinga, Jolanta Lissowska, Jan Lubiński, Marie Navratilova, Péter Rudnai, Neonila Szeszenia‐Dąbrowska, Simone Benhamou, Géraldine Cancel‐Tassin, Olivier Cussenot, Laura Baglietto, Heiner Boeing, Kay‐Tee Khaw, Elisabete Weiderpass, Börje Ljungberg, Raviprakash T. Sitaram, Fiona Bruinsma, Susan J. Jordan, Gianluca Severi, Ingrid Winship, Kristian Hveem, Lars J. Vatten, Tony Fletcher, Kvetoslava Koppová, Susanna C. Larsson, Alicja Wolk, Rosamonde E. Banks, Peter J. Selby, Douglas F. Easton, Paul D.P. Pharoah, Gabriella Andreotti, Laura E. Beane Freeman, Stella Koutros, Demetrius Albanes, Satu Männistö, Stephanie J. Weinstein, Peter E. Clark, Todd L. Edwards, Loren Lipworth, Susan M. Gapstur, Victoria L. Stevens, Hallie Carol, Matthew L. Freedman, Mark M. Pomerantz, Eunyoung Cho, Peter Kraft, Mark A. Preston, Kathryn M. Wilson, J. Michael Gaziano, Howard D. Sesso, Amanda Black, Neal D. Freedman, Wen‐Yi Huang, John Anema, Richard J. Kahnoski, Brian R. Lane, Sabrina L. Noyes, David Petillo, Bin Tean Teh, Ulrike Peters, Emily White and 23 more - Nature Communications 2017 cited by 140

  16. A whole-genome sequence and transcriptome perspective on HER2-positive breast cancers

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Carole Tarpin, C. Bouteille, Fabien Calvo, Marta Gut, Marta Gut, Sancha Martin, Serena Nik‐Zainal, Michael R. Stratton, Iris Pauporté, Pierre Saintigny, Daniel Birnbaum, Alain Viari, Gilles Thomas - Nature Communications 2016 cited by 159

  17. Diagnosis of Constitutional Mismatch Repair-Deficiency Syndrome Based on Microsatellite Instability and Lymphocyte Tolerance to Methylating Agents

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Thierry Frébourg, Jean–François Fléjou, Natacha Entz‐Werlé, Julie Leclerc, David Malka, Odile Cohen‐Haguenauer, Yael Goldberg, Anne‐Marie Gerdes, Faten Fedhila, Michèle Mathieu‐Dramard, Richard Hamelin, Wafaa Badre, Marion Gauthier‐Villars, Franck Bourdeaut, Eamonn Sheridan, Hans F. A. Vasen, Laurence Brugières, Katharina Wimmer, Martine Muleris, Alex Duval - Gastroenterology 2015 cited by 97

  18. Long-lasting Symptoms After an Acute COVID-19 Infection and Factors Associated With Their Resolution

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Nathanaël Lapidus, Isabelle Goderel, Céline Dorival, Jérôme Nicol, Olviier Robineau, Sofiane Kab, Adeline Renuy, Stéphane Le-Got, Céline Ribet, Miereille Pellicer, Emmanuel Wiernik, Marcel Goldberg, Fanny Artaud, Pascale Gerbouin-Rérolle, Mélodie nguix, C Laplanche, Roselyn Gomes-Rima, Lyan Hoang, Emmanuelle Correia, Alpha Amadou Barry, Nadège Senina, Julien Allègre, Fabien Szabo de Edelenyi, Nathalie Druesne-Pecollo, Yunes Esseddik, Serge Hercberg, Mélanie Deschasaux, Jean-Marc Sébaoun, Jean-Christophe Baudouin, Lætitia Gressin, Valérie Morel, Ouissam Ouili, Läétitia Ninove, Stéphane Priet, Paola Mariela Saba Villarroel, Toscane Fourié, Souand Mohamed Ali, Abdenour Amroun, Morgan Seston, Nazlı Ayhan, Boris Pastorino - JAMA Network Open 2022 cited by 65

  19. Building the sequence map of the human pan-genome

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , - Nature Biotechnology 2009 cited by 269

  20. NF1 Molecular Characterization and Neurofibromatosis Type I Genotype-Phenotype Correlation: The French Experience

    Authors: , , , , , , , , , , , , , , - Human Mutation 2013 cited by 175

  21. Identification and characterization of two functional variants in the human longevity gene FOXO3

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Stefan Schreiber, André Franke, Susanne Sebens, Almut Nebel - Nature Communications 2017 cited by 114

  22. Lung cancer susceptibility locus at 5p15.33

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Melissa M. Loomis, Jan Lubiński, Joanna Matyjasik, Marcin Lener, Dorota Oszutowska–Mazurek, John K. Field, Triantafillos Liloglou, George Xinarianos, Adrian Cassidy, Diana Zélénika, Anne Boland, Marc Délepine, Mario Foglio, Doris Lechner, Fumihiko Matsuda, Hélène Blanché, Marta Gut, Simon Heath, Mark Lathrop, Paul Brennan - Nature Genetics 2008 cited by 569

  23. Antibody status and cumulative incidence of SARS-CoV-2 infection among adults in three regions of France following the first lockdown and associated risk factors: a multicohort study

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , for the SAPRIS and SAPRIS-SERO study groups - International Journal of Epidemiology 2021 cited by 100

  24. Centenarians consistently present a younger epigenetic age than their chronological age with four epigenetic clocks based on a small number of CpG sites

    Authors: , , , , , , , - Aging 2022 cited by 35