litlas
Log inCreate account

Helga E. de Vries

Active 1989–2025

153
Papers
18,355
Citations
85
h-index
148
i10-index

Citations

Citations per year for Helga E. de Vries1992: 1 citations1993: 2 citations1994: 1 citations1995: 1 citations1997: 12 citations1998: 8 citations1999: 22 citations2000: 29 citations2001: 22 citations2002: 24 citations2003: 42 citations2004: 49 citations2005: 54 citations2006: 73 citations2007: 94 citations2008: 128 citations2009: 110 citations2010: 132 citations2011: 179 citations2012: 202 citations2013: 233 citations2014: 242 citations2015: 304 citations2016: 219 citations2017: 226 citations2018: 236 citations2019: 653 citations2020: 851 citations2021: 917 citations2022: 794 citations2023: 573 citations2024: 918 citations2025: 537 citations2026: 9 citations1996: no citations, so this year is not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 2,242 citing papers, 22.6% of this breakdownChina: 1,171 citing papers, 11.8% of this breakdownUnited Kingdom: 617 citing papers, 6.2% of this breakdownGermany: 613 citing papers, 6.2% of this breakdownNetherlands: 510 citing papers, 5.1% of this breakdownItaly: 465 citing papers, 4.7% of this breakdownCanada: 342 citing papers, 3.5% of this breakdownFrance: 325 citing papers, 3.3% of this breakdownSpain: 262 citing papers, 2.6% of this breakdownAustralia: 244 citing papers, 2.5% of this breakdownSwitzerland: 225 citing papers, 2.3% of this breakdownIndia: 223 citing papers, 2.2% of this breakdown
0%22.6%Other 27%

Institutions

Fields

  • Medicine36.3%
  • Neuroscience26.1%
  • Biochemistry, Genetics and Molecular Biology22.8%
  • Immunology and Microbiology6.5%
  • Materials Science3.3%
  • Engineering1.8%
  • Other3.2%

Topics

  • Neuroinflammation and Neurodegeneration Mechanisms7.7%
  • Barrier Structure and Function Studies4.9%
  • Multiple Sclerosis Research Studies4.1%
  • Alzheimer's disease research and treatments2.9%
  • Neurogenesis and neuroplasticity mechanisms2%
  • Immune cells in cancer1.7%
  • Other76.7%

Coauthors

All papers

Open in search
  1. Overcoming the blood–brain tumor barrier for effective glioblastoma treatment

    Authors: Olaf van Tellingen, Bahar Yetkin-Arik, Mark C. de Gooijer, Pieter Wesseling, Tom Würdinger, Helga E. de Vries - Drug Resistance Updates 2015 cited by 1,028

  2. The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence

    Authors: Jorge I. Alvarez, Aurore Dodelet-Devillers, Hania Kébir, Igal Ifergan, Pierre J. Fabre, Simone Terouz, Mike Sabbagh, Karolina Wosik, Lyne Bourbonnière, Monique Bernard, Jack van Horssen, Helga E. de Vries, Frédéric Charron, Alexandre Prat - Science 2011 cited by 837

  3. Amyloid Beta Induces Oxidative Stress-Mediated Blood–Brain Barrier Changes in Capillary Amyloid Angiopathy

    Authors: Anna Carrano, Jeroen J.M. Hoozemans, Saskia M. van der Vies, Annemieke J.M. Rozemüller, Jack van Horssen, Helga E. de Vries - Antioxidants and Redox Signaling 2011 cited by 291

  4. Inflammation of the choroid plexus in progressive multiple sclerosis: accumulation of granulocytes and T cells

    Authors: Sabela Rodríguez‐Lorenzo, Julia Konings, Susanne van der Pol, Alwin Kamermans, Sandra Amor, Jack van Horssen, Maarten E. Witte, Gijs Kooij, Helga E. de Vries - Acta Neuropathologica Communications 2020 cited by 101

  5. Pharmacokinetics, Brain Delivery, and Efficacy in Brain Tumor-Bearing Mice of Glutathione Pegylated Liposomal Doxorubicin (2B3-101)

    Authors: Pieter J. Gaillard, Chantal C.M. Appeldoorn, Rick Dorland, Joan van Kregten, Francesca Manca, Daniëlle J. Vugts, Albert D. Windhorst, Guus A.M.S. van Dongen, Helga E. de Vries, David Maussang, Olaf van Tellingen - PLoS ONE 2014 cited by 284

  6. T helper 17.1 cells associate with multiple sclerosis disease activity: perspectives for early intervention

    Authors: Jamie van Langelaar, Roos M. van der Vuurst de Vries, Malou Janssen, Annet F. Wierenga‐Wolf, Isis M Spilt, Theodora A. M. Siepman, Wendy Dankers, Georges M. G. M. Verjans, Helga E. de Vries, Erik Lubberts, Rogier Q. Hintzen, Marvin M. van Luijn - Brain 2018 cited by 222

  7. Succinate Is an Inflammation-Induced Immunoregulatory Metabolite in Macrophages

    Authors: Karl J. Harber, Kyra E. de Goede, Sanne G. S. Verberk, Elisa Meinster, Helga E. de Vries, Michel van Weeghel, Menno P.J. de Winther, Jan Van den Bossche - Metabolites 2020 cited by 138

  8. The influence of cytokines on the integrity of the blood-brain barrier in vitro

    Authors: Helga E. de Vries, Margret C.M. Blom-Roosemalen, Marijke van Oosten, Albert G. de Boer, Theo J.C. van Berkel, D. D. Breimer, Johan Kuiper - Journal of Neuroimmunology 1996 cited by 667

  9. Immune cell trafficking across the barriers of the central nervous system in multiple sclerosis and stroke

    Authors: Melissa A Lopes Pinheiro, Gijs Kooij, Mark R. Mizee, Alwin Kamermans, Gaby Enzmann, Ruth Lyck, Markus Schwaninger, Britta Engelhardt, Helga E. de Vries - Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2015 cited by 248

  10. Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques

    Authors: Jeroen Baardman, Sanne G. S. Verberk, Saskia van der Velden, Marion J. Gijbels, Cindy P.P.A. van Roomen, Judith C. Sluimer, Jelle Y. Broos, Guillermo R. Griffith, Koen H.M. Prange, Michel van Weeghel, Soufyan Lakbir, Douwe Molenaar, Elisa Meinster, Annette E. Neele, Gijs Kooij, Helga E. de Vries, Esther Lutgens, Kathryn E. Wellen, Menno P.J. de Winther, Jan Van den Bossche - Nature Communications 2020 cited by 127

  11. Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signaling

    Authors: Gerty Schreibelt, Gijs Kooij, Arie Reijerkerk, Ruben van Doorn, Sonja I. Gringhuis, Susanne M. A. van der Pol, Babette B. Weksler, Ignacio A. Romero, Pierre‐Olivier Couraud, Jörg Piontek, Ingolf E. Blasig, Christine D. Dijkstra, Eric Ronken, Helga E. de Vries - The FASEB Journal 2007 cited by 353

  12. Neuroinflammation and Blood-Brain Barrier Changes in Capillary Amyloid Angiopathy

    Authors: Anna Carrano, Jeroen J.M. Hoozemans, Saskia M. van der Vies, Jack van Horssen, Helga E. de Vries, Annemieke J.M. Rozemüller - Neurodegenerative Diseases 2012 cited by 185

  13. Inflammation-induced endothelial to mesenchymal transition promotes brain endothelial cell dysfunction and occurs during multiple sclerosis pathophysiology

    Authors: Claudio Derada Troletti, Ruud D. Fontijn, Elizabeth Gowing, Marc Charabati, Bert van het Hof, Imad Didouh, Susanne M. A. van der Pol, Dirk Geerts, Alexandre Prat, Jack van Horssen, Gijs Kooij, Helga E. de Vries - Cell Death and Disease 2019 cited by 98

  14. Human BBB-on-a-chip reveals barrier disruption, endothelial inflammation, and T cell migration under neuroinflammatory conditions

    Authors: Arya Lekshmi Nair, Linda Groenendijk, Roos Overdevest, Tania M. Fowke, Rumaisha Annida, Orsola Mocellin, Helga E. de Vries, Nienke R. Wevers - Frontiers in Molecular Neuroscience 2023 cited by 75

  15. Vascular Hypothesis of Alzheimer Disease

    Authors: Sanny Scheffer, Dorien M. A. Hermkens, Louise van der Weerd, Helga E. de Vries, Mat J.A.P. Daemen - Arteriosclerosis Thrombosis and Vascular Biology 2021 cited by 99

  16. Neurovascular dysfunction in GRN-associated frontotemporal dementia identified by single-nucleus RNA sequencing of human cerebral cortex

    Authors: Emma Gerrits, Lucia Giannini, Nieske Brouwer, Shamiram Melhem, Danielle Seilhean, Isabelle Le Ber, The Brainbank Neuro-CEB Neuropathology Network, Alwin Kamermans, Gijs Kooij, Helga E. de Vries, Erik Boddeke, Harro Seelaar, John C. van Swieten, Bart J. L. Eggen - Nature Neuroscience 2022 cited by 90

  17. Meningeal inflammation in multiple sclerosis induces phenotypic changes in cortical microglia that differentially associate with neurodegeneration

    Authors: Lynn van Olst, Carla Rodriguez-Mogeda, Carmen Picón, Svenja Kiljan, Rachel James, Alwin Kamermans, Susanne M. A. van der Pol, Lydian Knoop, Iliana Michailidou, Evelien H.G.M. Drost, Marc Franssen, Geert J. Schenk, Jeroen Geurts, Sandra Amor, Nicholas D. Mazarakis, Jack van Horssen, Helga E. de Vries, Richard Reynolds, Maarten E. Witte - Acta Neuropathologica 2021 cited by 83

  18. Clusters of activated microglia in normal-appearing white matter show signs of innate immune activation

    Authors: Jack van Horssen, Shailender Singh, Susanne van der Pol, Markus Kipp, Jamie Lim, Laura A. N. Peferoen, Wouter H. Gerritsen, Evert‐Jan Kooi, Maarten E. Witte, Jeroen J.G. Geurts, Helga E. de Vries, Regina Peferoen‐Baert, Peter J. van den Elsen, Paul van der Valk, Sandra Amor - Journal of Neuroinflammation 2012 cited by 200

  19. Modeling ischemic stroke in a triculture neurovascular unit on-a-chip

    Authors: Nienke R. Wevers, Arya Lekshmi Nair, Tania M. Fowke, Maria Pontier, Dhanesh G. Kasi, Xandor M. Spijkers, Charlie Hallard, Gwenaëlle Rabussier, Remko van Vught, Paul Vulto, Helga E. de Vries, Henriëtte L. Lanz - Fluids and Barriers of the CNS 2021 cited by 70

  20. Induction of brain‐infiltrating T‐bet–expressing B cells in multiple sclerosis

    Authors: Jamie van Langelaar, Liza Rijvers, Malou Janssen, Annet F. Wierenga‐Wolf, Marie‐José Melief, Theodora A. M. Siepman, Helga E. de Vries, Peter‐Paul A. Unger, S. Marieke van Ham, Rogier Q. Hintzen, Marvin M. van Luijn - Annals of Neurology 2019 cited by 105

  21. Purinergic receptors P2Y12R and P2X7R: potential targets for PET imaging of microglia phenotypes in multiple sclerosis

    Authors: Wissam Beaino, Bieneke Janssen, Gijs Kooij, Susanne M. A. van der Pol, Bert van het Hof, Jack van Horssen, Albert D. Windhorst, Helga E. de Vries - Journal of Neuroinflammation 2017 cited by 145

  22. Specialized pro-resolving lipid mediators are differentially altered in peripheral blood of patients with multiple sclerosis and attenuate monocyte and blood-brain barrier dysfunction

    Authors: Gijs Kooij, Claudio Derada Troletti, Alessandro Leuti, Paul C. Norris, Ian R. Riley, Maria Albanese, Serena Ruggieri, Stephania Libreros, Susanne M. A. van der Pol, Bert van het Hof, Yoëlle Schell, Gisella Guerrera, Fabio Buttari, Nicola Biagio Mercuri, Diego Centonze, Claudio Gasperini, Luca Battistini, Helga E. de Vries, Charles N. Serhan, Valerio Chiurchiù - Haematologica 2019 cited by 120

  23. Extended interval dosing of ocrelizumab modifies the repopulation of B cells without altering the clinical efficacy in multiple sclerosis

    Authors: Carla Rodriguez-Mogeda, Zoë YGJ van Lierop, Susanne M. A. van der Pol, Loet Coenen, Laura Hogenboom, Alwin Kamermans, Ernesto Rodríguez, Jack van Horssen, Zoé L. E. van Kempen, Bernard M.J. Uitdehaag, Charlotte E. Teunissen, Maarten E. Witte, Joep Killestein, Helga E. de Vries - Journal of Neuroinflammation 2023 cited by 36

  24. Astrocytic ceramide as possible indicator of neuroinflammation

    Authors: Nienke M. de Wit, Sandra den Hoedt, Pilar Martínez‐Martínez, Annemieke J.M. Rozemüller, Monique Mulder, Helga E. de Vries - Journal of Neuroinflammation 2019 cited by 101