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Hideyoshi Harashima

Active 1984–2025

189
Papers
21,578
Citations
87
h-index
181
i10-index

Citations

Citations per year for Hideyoshi Harashima1975: 1 citations1986: 1 citations1990: 1 citations1991: 1 citations1994: 1 citations1995: 3 citations1996: 2 citations1997: 2 citations1998: 7 citations1999: 1 citations2000: 5 citations2001: 10 citations2002: 7 citations2003: 21 citations2004: 34 citations2005: 35 citations2006: 93 citations2007: 149 citations2008: 144 citations2009: 183 citations2010: 230 citations2011: 233 citations2012: 256 citations2013: 243 citations2014: 232 citations2015: 220 citations2016: 214 citations2017: 231 citations2018: 178 citations2019: 633 citations2020: 892 citations2021: 825 citations2022: 903 citations2023: 849 citations2024: 1,188 citations2025: 841 citations2026: 18 citations1976–1985: no citations, so these years are not shown1987–1989: no citations, so these years are not shown1992–1993: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorChina: 1,762 citing papers, 22.2% of this breakdownUnited States: 1,539 citing papers, 19.4% of this breakdownJapan: 525 citing papers, 6.6% of this breakdownIndia: 354 citing papers, 4.5% of this breakdownUnited Kingdom: 295 citing papers, 3.7% of this breakdownGermany: 287 citing papers, 3.6% of this breakdownSouth Korea: 242 citing papers, 3% of this breakdownItaly: 192 citing papers, 2.4% of this breakdownIran: 184 citing papers, 2.3% of this breakdownFrance: 183 citing papers, 2.3% of this breakdownCanada: 180 citing papers, 2.3% of this breakdownAustralia: 178 citing papers, 2.2% of this breakdown
0%22.2%Other 25.5%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology50.9%
  • Medicine14.3%
  • Materials Science14.1%
  • Immunology and Microbiology9.2%
  • Engineering5.4%
  • Pharmacology, Toxicology and Pharmaceutics3.1%
  • Other3%

Topics

  • RNA Interference and Gene Delivery16.3%
  • Advanced biosensing and bioanalysis techniques9.1%
  • Nanoparticle-Based Drug Delivery7.5%
  • Nanoplatforms for cancer theranostics4.2%
  • Immunotherapy and Immune Responses3.3%
  • Virus-based gene therapy research3.1%
  • Other56.5%

Coauthors

All papers

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  1. Clinical translation of nanomedicines: Challenges, opportunities, and keys

    Authors: Mahmoud A. Younis, Hesham M. Tawfeek, Ahmed A. H. Abdellatif, Jelan A. Abdel-Aleem, Hideyoshi Harashima - Advanced Drug Delivery Reviews 2021 cited by 392

  2. STING agonist loaded lipid nanoparticles overcome anti-PD-1 resistance in melanoma lung metastasis via NK cell activation

    Authors: Takashi Nakamura, Takanori Sato, Rikito Endo, Shun Sasaki, Naomichi Takahashi, Yusuke Sato, Mamoru Hyodo, Yoshihiro Hayakawa, Hideyoshi Harashima - Journal for ImmunoTherapy of Cancer 2021 cited by 251

  3. The Effect of Size and Charge of Lipid Nanoparticles Prepared by Microfluidic Mixing on Their Lymph Node Transitivity and Distribution

    Authors: Takashi Nakamura, Minori Kawai, Yusuke Sato, Masatoshi Maeki, Manabu Tokeshi, Hideyoshi Harashima - Molecular Pharmaceutics 2020 cited by 178

  4. Extrahepatic targeting of lipid nanoparticles in vivo with intracellular targeting for future nanomedicines

    Authors: Takashi Nakamura, Yusuke Sato, Yuma Yamada, Mahmoud M. Abd Elwakil, Seigo Kimura, Mahmoud A. Younis, Hideyoshi Harashima - Advanced Drug Delivery Reviews 2022 cited by 116

  5. Understanding structure-activity relationships of pH-sensitive cationic lipids facilitates the rational identification of promising lipid nanoparticles for delivering siRNAs in vivo

    Authors: Yusuke Sato, Kazuki Hashiba, Kosuke Sasaki, Masatoshi Maeki, Manabu Tokeshi, Hideyoshi Harashima - Journal of Controlled Release 2019 cited by 175

  6. Branching Ionizable Lipids Can Enhance the Stability, Fusogenicity, and Functional Delivery of mRNA

    Authors: Kazuki Hashiba, Yusuke Sato, Masamitsu Taguchi, Sachiko Sakamoto, Ayaka Otsu, Yoshiki Maeda, Takuya Shishido, Masao Murakawa, Okazaki Arimichi, Hideyoshi Harashima - Small Science 2022 cited by 78

  7. The Polyethyleneglycol Dilemma: Advantage and Disadvantage of PEGylation of Liposomes for Systemic Genes and Nucleic Acids Delivery to Tumors

    Authors: Hiroto Hatakeyama, Hidetaka Akita, Hideyoshi Harashima - Biological and Pharmaceutical Bulletin 2013 cited by 484

  8. Understanding the formation mechanism of lipid nanoparticles in microfluidic devices with chaotic micromixers

    Authors: Masatoshi Maeki, Yuka FUJISHIMA, Yusuke Sato, Takao Yasui, Noritada Kaji, Akihiko Ishida, Hirofumi Tani, Yoshinobu Baba, Hideyoshi Harashima, Manabu Tokeshi - PLoS ONE 2017 cited by 187

  9. Advances in microfluidics for lipid nanoparticles and extracellular vesicles and applications in drug delivery systems

    Authors: Masatoshi Maeki, Niko Kimura, Yusuke Sato, Hideyoshi Harashima, Manabu Tokeshi - Advanced Drug Delivery Reviews 2018 cited by 308

  10. Ultra-small lipid nanoparticles encapsulating sorafenib and midkine-siRNA selectively-eradicate sorafenib-resistant hepatocellular carcinoma in vivo

    Authors: Mahmoud A. Younis, Ikramy A. Khalil, Yaser Hosny Ali Elewa, Yasuhiro Kon, Hideyoshi Harashima - Journal of Controlled Release 2021 cited by 115

  11. On the size-regulation of RNA-loaded lipid nanoparticles synthesized by microfluidic device

    Authors: Kento Okuda, Yusuke Sato, Kazuki Iwakawa, Kosuke Sasaki, Nana Okabe, Masatoshi Maeki, Manabu Tokeshi, Hideyoshi Harashima - Journal of Controlled Release 2022 cited by 88

  12. Endocytosis of Gene Delivery Vectors: From Clathrin-dependent to Lipid Raft-mediated Endocytosis

    Authors: Ayman El‐Sayed, Hideyoshi Harashima - Molecular Therapy 2013 cited by 344

  13. The Effect of Cryoprotectants and Storage Conditions on the Transfection Efficiency, Stability, and Safety of Lipid‐Based Nanoparticles for mRNA and DNA Delivery

    Authors: Konstantinos N. Kafetzis, Natalia Papalamprou, Elisha McNulty, Kai Xin Thong, Yusuke Sato, Mironov Aa, Atul Purohit, Philip J. Welsby, Hideyoshi Harashima, Cynthia Yu‐Wai‐Man, Aristides D. Tagalakis - Advanced Healthcare Materials 2023 cited by 83

  14. mRNA-Loaded Lipid Nanoparticles Targeting Immune Cells in the Spleen for Use as Cancer Vaccines

    Authors: Ryoya Shimosakai, Ikramy A. Khalil, Seigo Kimura, Hideyoshi Harashima - Pharmaceuticals 2022 cited by 53

  15. Challenges in Promoting Mitochondrial Transplantation Therapy

    Authors: Yuma Yamada, Momo Ito, Manae Arai, Mitsue Hibino, Takao Tsujioka, Hideyoshi Harashima - International Journal of Molecular Sciences 2020 cited by 106

  16. Overcoming thermostability challenges in mRNA–lipid nanoparticle systems with piperidine-based ionizable lipids

    Authors: Kazuki Hashiba, Masamitsu Taguchi, Sachiko Sakamoto, Ayaka Otsu, Yoshiki Maeda, Hirofumi Ebe, Okazaki Arimichi, Hideyoshi Harashima, Yusuke Sato - Communications Biology 2024 cited by 71

  17. Development of the iLiNP Device: Fine Tuning the Lipid Nanoparticle Size within 10 nm for Drug Delivery

    Authors: Niko Kimura, Masatoshi Maeki, Yusuke Sato, Yusuke Note, Akihiko Ishida, Hirofumi Tani, Hideyoshi Harashima, Manabu Tokeshi - ACS Omega 2018 cited by 216

  18. Manipulating the function of tumor-associated macrophages by siRNA-loaded lipid nanoparticles for cancer immunotherapy

    Authors: Nour Shobaki, Yusuke Sato, Yuichi Suzuki, Nana Okabe, Hideyoshi Harashima - Journal of Controlled Release 2020 cited by 111

  19. A multifunctional envelope type nano device (MEND) for gene delivery to tumours based on the EPR effect: A strategy for overcoming the PEG dilemma

    Authors: Hiroto Hatakeyama, Hidetaka Akita, Hideyoshi Harashima - Advanced Drug Delivery Reviews 2010 cited by 640

  20. Different kinetics for the hepatic uptake of lipid nanoparticles between the apolipoprotein E/low density lipoprotein receptor and the N-acetyl-d-galactosamine/asialoglycoprotein receptor pathway

    Authors: Yusuke Sato, Yoshiyuki Kinami, Kazuki Hashiba, Hideyoshi Harashima - Journal of Controlled Release 2020 cited by 93

  21. Development of a Microfluidic-Based Post-Treatment Process for Size-Controlled Lipid Nanoparticles and Application to siRNA Delivery

    Authors: Niko Kimura, Masatoshi Maeki, Yusuke Sato, Akihiko Ishida, Hirofumi Tani, Hideyoshi Harashima, Manabu Tokeshi - ACS Applied Materials & Interfaces 2020 cited by 102

  22. Novel lipid combination for delivery of plasmid DNA to immune cells in the spleen

    Authors: Seigo Kimura, Ikramy A. Khalil, Yaser Hosny Ali Elewa, Hideyoshi Harashima - Journal of Controlled Release 2021 cited by 81

  23. mRNA-Loaded Lipid Nanoparticles Targeting Dendritic Cells for Cancer Immunotherapy

    Authors: Kosuke Sasaki, Yusuke Sato, Kento Okuda, Kazuki Iwakawa, Hideyoshi Harashima - Pharmaceutics 2022 cited by 67

  24. Liposomes loaded with a STING pathway ligand, cyclic di-GMP, enhance cancer immunotherapy against metastatic melanoma

    Authors: Takashi Nakamura, Hiroko Miyabe, Mamoru Hyodo, Yusuke Sato, Yoshihiro Hayakawa, Hideyoshi Harashima - Journal of Controlled Release 2015 cited by 198