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Hideyuki Okano

Active 1985–2025

486
Papers
68,664
Citations
143
h-index
457
i10-index

Citations

Citations per year for Hideyuki Okano1978: 2 citations1985: 2 citations1986: 1 citations1987: 2 citations1988: 8 citations1989: 2 citations1990: 6 citations1991: 2 citations1992: 14 citations1993: 15 citations1994: 27 citations1995: 36 citations1996: 30 citations1997: 46 citations1998: 52 citations1999: 84 citations2000: 146 citations2001: 214 citations2002: 305 citations2003: 306 citations2004: 301 citations2005: 477 citations2006: 564 citations2007: 649 citations2008: 644 citations2009: 660 citations2010: 723 citations2011: 785 citations2012: 772 citations2013: 771 citations2014: 788 citations2015: 733 citations2016: 634 citations2017: 655 citations2018: 562 citations2019: 2,070 citations2020: 2,265 citations2021: 2,270 citations2022: 1,810 citations2023: 1,310 citations2024: 1,907 citations2025: 872 citations2026: 16 citations1979–1984: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 7,689 citing papers, 28.3% of this breakdownChina: 2,998 citing papers, 11% of this breakdownJapan: 2,738 citing papers, 10.1% of this breakdownUnited Kingdom: 1,620 citing papers, 6% of this breakdownGermany: 1,517 citing papers, 5.6% of this breakdownItaly: 919 citing papers, 3.4% of this breakdownCanada: 860 citing papers, 3.2% of this breakdownFrance: 835 citing papers, 3.1% of this breakdownAustralia: 639 citing papers, 2.3% of this breakdownSpain: 630 citing papers, 2.3% of this breakdownSouth Korea: 505 citing papers, 1.9% of this breakdownSwitzerland: 470 citing papers, 1.7% of this breakdown
0%28.3%Other 21.1%

Institutions

Fields

  • Medicine37.3%
  • Biochemistry, Genetics and Molecular Biology32.7%
  • Neuroscience23.4%
  • Immunology and Microbiology2.1%
  • Engineering1.3%
  • Agricultural and Biological Sciences0.9%
  • Other2.3%

Topics

  • Neurogenesis and neuroplasticity mechanisms5.2%
  • Pluripotent Stem Cells Research3.3%
  • Autophagy in Disease and Therapy3.2%
  • Neuroinflammation and Neurodegeneration Mechanisms2.7%
  • Nerve injury and regeneration2.5%
  • Mesenchymal stem cell research2.5%
  • Other80.6%

Coauthors

All papers

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  1. Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

    Authors: Taichi Hara, Kenji Nakamura, Makoto Matsui, Akitsugu Yamamoto, Yohko Nakahara, Rika Suzuki-Migishima, Minesuke Yokoyama, Kenji Mishima, Ichiro Saito, Hideyuki Okano, Noboru Mizushima - Nature 2006 cited by 3,872

  2. Single-cell bioluminescence imaging of deep tissue in freely moving animals

    Authors: Satoshi Iwano, Mayu Sugiyama, Hiroshi Hama, Akiya Watakabe, Naomi Hasegawa, Takahiro Kuchimaru, Kazumasa Z. Tanaka, Megumu Takahashi, Yoko Ishida, Junichi Hata, Satoshi Shimozono, Kana Namiki, Takashi Fukano, Masahiro Kiyama, Hideyuki Okano, Shinae Kizaka‐Kondoh, Thomas J. McHugh, Tetsuo Yamamori, Hiroyuki Hioki, Shôjirô Maki, Atsushi Miyawaki - Science 2018 cited by 493

  3. The liver–brain–gut neural arc maintains the Treg cell niche in the gut

    Authors: Toshiaki Teratani, Yohei Mikami, Nobuhiro Nakamoto, Takahiro Suzuki, Yosuke Harada, Koji Okabayashi, Yuya Hagihara, Nobuhito Taniki, Keita Kohno, Shinsuke Shibata, Kentaro Miyamoto, Harumichi Ishigame, Po–Sung Chu, Tomohisa Sujino, Wataru Suda, Masahira Hattori, M. Matsui, Takaharu Okada, Hideyuki Okano, Masayuki Inoue, Toshihiko Yada, Yuko Kitagawa, Akihiko Yoshimura, Mamoru Tanida, Makoto Tsuda, Yusaku Iwasaki, Takanori Kanai∥ - Nature 2020 cited by 258

  4. Reactive astrocytes function as phagocytes after brain ischemia via ABCA1-mediated pathway

    Authors: Yosuke M. Morizawa, Yuri Hirayama, Nobuhiko Ohno, Shinsuke Shibata, Eiji Shigetomi, Yang Sui, Junichi Nabekura, Kōichi Sato, Fumikazu Okajima, Hirohide Takebayashi, Hideyuki Okano, Schuichi Koizumi - Nature Communications 2017 cited by 429

  5. iPSC-based disease modeling and drug discovery in cardinal neurodegenerative disorders

    Authors: Hideyuki Okano, Satoru Morimoto - Cell stem cell 2022 cited by 212

  6. Conditional ablation of Stat3 or Socs3 discloses a dual role for reactive astrocytes after spinal cord injury

    Authors: Seiji Okada, Masaya Nakamura, Hiroyuki Katoh, Tamaki Miyao, Takuya Shimazaki, Ken Ishii, Junichi Yamane, Akihiko Yoshimura, Yukihide Iwamoto, Yoshiaki Toyama, Hideyuki Okano - Nature Medicine 2006 cited by 984

  7. Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc

    Authors: Daisuke Sakai, Yoshihiko Nakamura, Tomoko Nakai, Taishi Mishima, Shunichi Kato, Sibylle Grad, Mauro Alini, Makarand V. Risbud, Danny Chan, Kathryn S.E. Cheah, Ken–ichi Yamamura, Koichi Masuda, Hideyuki Okano, Kiyoshi Ando, Joji Mochida - Nature Communications 2012 cited by 449

  8. First-in-human clinical trial of transplantation of iPSC-derived NS/PCs in subacute complete spinal cord injury: Study protocol

    Authors: Keiko Sugai, Miho Sumida, Tomoko Shofuda, Ryo Yamaguchi, Takashi Tamura, Tsuneo Kohzuki, Takayuki Abe, Reo Shibata, Yasuhiro Kamata, Shuhei Ito, Toshiki Okubo, Osahiko Tsuji, Satoshi Nori, Narihito Nagoshi, Shinya Yamanaka, Shin Kawamata, Yonehiro Kanemura, Masaya Nakamura, Hideyuki Okano - Regenerative Therapy 2021 cited by 159

  9. Prospective identification, isolation, and systemic transplantation of multipotent mesenchymal stem cells in murine bone marrow

    Authors: Satoru Morikawa, Yo Mabuchi, Yoshiaki Kubota, Yasuo Nagai, Kunimichi Niibe, Emi Hiratsu, Sadafumi Suzuki, Chikako Miyauchi-Hara, Narihito Nagoshi, Takehiko Sunabori, Shigeto Shimmura, Atsushi Miyawaki, Taneaki Nakagawa, Toshio Suda, Hideyuki Okano, Yumi Matsuzaki - The Journal of Experimental Medicine 2009 cited by 831

  10. Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent

    Authors: Koki Fujimori, Mitsuru Ishikawa, Asako Otomo, Naoki Atsuta, Ryoichi Nakamura, Tetsuya Akiyama, Shinji Hadano, Masashi Aoki, Hideyuki Saya, Gen Sobue, Hideyuki Okano - Nature Medicine 2018 cited by 513

  11. Common functional networks in the mouse brain revealed by multi-centre resting-state fMRI analysis

    Authors: Joanes Grandjean, Carola Canella, Cynthia Anckaerts, Gülebru Ayrancı, Salma Bougacha, Thomas Bienert, David Buehlmann, Ludovico Coletta, Daniel Gallino, Natalia Gass, Clément M. Garin, Nachiket A. Nadkarni, Neele S. Hübner, Meltem Karatas, Yuji Komaki, Silke Kreitz, Francesca Mandino, Anna E. Mechling, Chika Sato, Katja Sauer, Disha Shah, Sandra Strobelt, Norio Takata, Isabel Wank, Tong Wu, Noriaki Yahata, Ling Yun Yeow, Yohan Yee, Ichio Aoki, M. Mallar Chakravarty, Wei‐Tang Chang, Marc Dhénain, Dominik von Elverfeldt, Laura Harsan, Andreas Heß, Tianzi Jiang, Georgios A. Keliris, Jason P. Lerch, Andreas Meyer‐Lindenberg, Hideyuki Okano, Markus Rudin, Alexander Sartorius, Annemie Van der Linden, Marleen Verhoye, Wolfgang Weber‐Fahr, Nicole Wenderoth, Valerio Zerbi, Alessandro Gozzi - NeuroImage 2019 cited by 235

  12. Sema3A regulates bone-mass accrual through sensory innervations

    Authors: Toru Fukuda, Shu Takeda, Ren Xu, Hiroki Ochi, Satoko Sunamura, Tsuyoshi Sato, Shinsuke Shibata, Yutaka Yoshida, Zirong Gu, Ayako Kimura, Chengshan Ma, Cheng Xu, Waka Bando, Koji Fujita, Kenichi Shinomiya, Takashi Hirai, Yoshinori Asou, Mitsuhiro Enomoto, Hideyuki Okano, Atsushi Okawa, Hiroshi Itoh - Nature 2013 cited by 412

  13. Associations of cardiovascular biomarkers and plasma albumin with exceptional survival to the highest ages

    Authors: Takumi Hirata, Yasumichi Arai, Shinsuke Yuasa, Yukiko Abe, Michiyo Takayama, Takashi Sasaki, Akira Kunitomi, Hiroki Inagaki, Motoyoshi Endo, Jun Morinaga, Kimio Yoshimura, Tetsuo Adachi, Yuichi Oike, Toru Takebayashi, Hideyuki Okano, Nobuyoshi Hirose - Nature Communications 2020 cited by 133

  14. Phase 1/2a clinical trial in ALS with ropinirole, a drug candidate identified by iPSC drug discovery

    Authors: Satoru Morimoto, Shinichi Takahashi, Daisuke Ito, Yugaku Daté, Kensuke Okada, Chris Kato, Shiho Nakamura, Fumiko Ozawa, Chai Muh Chyi, Ayumi Nishiyama, Naoki Suzuki, Koki Fujimori, Tosho Kondo, Masaki Takao, Miwa Hirai, Yasuaki Kabe, Makoto Suematsu, Masahiro Jinzaki, Masashi Aoki, Yuto Fujiki, Yasunori Sato, Norihiro Suzuki, Jin Nakahara, Hideyuki Okano - Cell stem cell 2023 cited by 109

  15. Grafted human-induced pluripotent stem-cell–derived neurospheres promote motor functional recovery after spinal cord injury in mice

    Authors: Satoshi Nori, Yohei Okada, Akimasa Yasuda, Osahiko Tsuji, Yuichiro Takahashi, Yoshiomi Kobayashi, Kanehiro Fujiyoshi, Masato Koike, Yasuo Uchiyama, Eiji Ikeda, Yoshiaki Toyama, Shinya Yamanaka, Masaya Nakamura, Hideyuki Okano - National Academy of Sciences, Proceedings of the National Academy of Sciences 2011 cited by 559

  16. Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men

    Authors: Junichiro Irie, Emi Inagaki, Masataka Fujita, Hideaki Nakaya, Masanori Mitsuishi, Shintaro Yamaguchi, Kazuya Yamashita, Shuhei Shigaki, Takashi Ono, Hideo Yukioka, Hideyuki Okano, Yo-ichi Nabeshima, Shin‐ichiro Imai, Masato Yasui, Kazuo Tsubota, Hiroshi Itoh - Endocrine Journal 2019 cited by 190

  17. Modeling familial Alzheimer's disease with induced pluripotent stem cells

    Authors: Takuya Yagi, Daisuke Ito, Yohei Okada, Wado Akamatsu, Yoshihiro Nihei, Takahito Yoshizaki, Shinya Yamanaka, Hideyuki Okano, Norihiro Suzuki - Human Molecular Genetics 2011 cited by 604

  18. Astrocyte-Derived Exosomes Treated With a Semaphorin 3A Inhibitor Enhance Stroke Recovery via Prostaglandin D 2 Synthase

    Authors: Kenichiro Hira, Yuji Ueno, Ryota Tanaka, Nobukazu Miyamoto, Kazuo Yamashiro, Toshiki Inaba, Takao Urabe, Hideyuki Okano, Nobutaka Hattori - Stroke 2018 cited by 110

  19. Long-term selective stimulation of transplanted neural stem/progenitor cells for spinal cord injury improves locomotor function

    Authors: Momotaro Kawai, Kent Imaizumi, Mitsuru Ishikawa, Shinsuke Shibata, Munehisa Shinozaki, Takahiro Shibata, Shogo Hashimoto, Takahiro Kitagawa, Kentaro Ago, Keita Kajikawa, Reo Shibata, Yasuhiro Kamata, Junichi Ushiba, K. Koga, Hidemasa Furue, Morio Matsumoto, Masaya Nakamura, Narihito Nagoshi, Hideyuki Okano - Cell Reports 2021 cited by 80

  20. STAT3-dependent reactive astrogliosis in the spinal dorsal horn underlies chronic itch

    Authors: Miho Shiratori‐Hayashi, K. Koga, Hidetoshi Tozaki‐Saitoh, Yuta Kohro, Honami Toyonaga, Yamaguchi Chiharu, Ayumi Hasegawa, Takeshi Nakahara, Junichi Hachisuka, Shizuo Akira, Hideyuki Okano, Masutaka Furue, Kazuhide Inoue, Makoto Tsuda - Nature Medicine 2015 cited by 220

  21. Opportunities and limitations of genetically modified nonhuman primate models for neuroscience research

    Authors: Guoping Feng, Frances E. Jensen, Henry T. Greely, Hideyuki Okano, Stefan Treue, Angela Roberts, James G. Fox, Sarah J. Caddick, Mu-ming Poo, William T. Newsome, John H. Morrison - National Academy of Sciences, Proceedings of the National Academy of Sciences 2020 cited by 124

  22. YAP-dependent necrosis occurs in early stages of Alzheimer’s disease and regulates mouse model pathology

    Authors: Hikari Tanaka, Hidenori Homma, Kyota Fujita, Kanoh Kondo, Shingo Yamada, Xiaocen Jin, Masaaki Waragai, Gaku Ohtomo, Atsushi Iwata, Kazuhiko Tagawa, Naoki Atsuta, Masahisa Katsuno, Naoki Tomita, Katsutoshi Furukawa, Yuko Saito, Takashi Saito, Ayaka Ichise, Shinsuke Shibata, Hiroyuki Arai, Takaomi C. Saido, Marius Sudol, Shin‐ichi Muramatsu, Hideyuki Okano, Elliott J. Mufson, Gen Sobue, Shigeo Murayama, Hitoshi Okazawa - Nature Communications 2020 cited by 116

  23. A framework for neural organoids, assembloids and transplantation studies

    Authors: Sergiu P. Pașca, Paola Arlotta, Helen S. Bateup, J. Gray Camp, Silvia Cappello, Fred H. Gage, Juergen A. Knoblich, Arnold R. Kriegstein, Madeline A. Lancaster, Guo‐li Ming, Gaia Novarino, Hideyuki Okano, Malin Parmar, In‐Hyun Park, Orly Reiner, Hongjun Song, Lorenz Studer, Jun Takahashi, Sally Temple, Giuseppe Testa, Barbara Treutlein, Flora M. Vaccarino, Pierre Vanderhaeghen, Tracy L. Young‐Pearse - Nature 2024 cited by 91

  24. Semi-supervised deep learning of brain tissue segmentation

    Authors: Ryo Ito, Ken Nakae, Junichi Hata, Hideyuki Okano, Shin Ishii - Neural Networks 2019 cited by 81