Howard L. McLeod
Active 1992–2025
- Also published as
- Howard L McLeod
- 165
- Papers
- 31,281
- Citations
- 101
- h-index
- 164
- i10-index
Citations
Citation sources
Countries
Institutions
- Harvard University0.6%
- Stanford University0.6%
- Mayo Clinic0.5%
- Inserm0.5%
- St. Jude Children's Research Hospital0.5%
- University of Toronto0.4%
- Other96.9%
Fields
- Medicine46.9%
- Biochemistry, Genetics and Molecular Biology26.8%
- Pharmacology, Toxicology and Pharmaceutics15.8%
- Computer Science2%
- Materials Science1.8%
- Immunology and Microbiology1.1%
- Other5.6%
Topics
- Pharmacogenetics and Drug Metabolism7%
- Colorectal Cancer Treatments and Studies2.8%
- Drug Transport and Resistance Mechanisms2.7%
- Computational Drug Discovery Methods2.2%
- Cancer Genomics and Diagnostics1.8%
- Cancer Treatment and Pharmacology1.8%
- Other81.7%
Coauthors
- Sharon Marsh26
- Teri E. Klein14
- Mary V. Relling11
- William E. Evans9
- Mark J. Ratain8
- Dan M. Roden7
- Russ B. Altman7
- Yijing He7
- Brian F. Gage6
- Daniel L. Hertz6
- Graeme I. Murray6
- Kelly E. Caudle6
- Matthias Schwab6
- Richard M. Weinshilboum6
- Todd C. Knepper6
- Wei Zhang6
- Caroline F. Thorn5
- Christine M. Walko5
- Deepak Voora5
- Kouros Owzar5
- Marc S. Williams5
- Michelle Whirl‐Carrillo5
- Michiaki Kubo5
- Rex L. Chisholm5
All papers
- Doxorubicin pathways
Authors: Caroline F. Thorn, Connie Oshiro, Sharon Marsh, Tina Hernandez‐Boussard, Howard L. McLeod, Teri E. Klein, Russ B. Altman - Pharmacogenetics and Genomics 2010 cited by 1,614
- Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Dihydropyrimidine Dehydrogenase Genotype and Fluoropyrimidine Dosing: 2017 Update
Authors: Ursula Amstutz, Linda M. Henricks, Steven M. Offer, Julia M. Barbarino, Jan H.M. Schellens, Jesse J. Swen, Teri E. Klein, Howard L. McLeod, Kelly E. Caudle, Robert B. Diasio, Matthias Schwab - Clinical Pharmacology & Therapeutics 2017 cited by 657
- A genome-based model for adjusting radiotherapy dose (GARD): a retrospective, cohort-based study
Authors: Jacob G. Scott, Anders Berglund, Michael J. Schell, I Mihaylov, William J. Fulp, Binglin Yue, Eric A. Welsh, Jimmy J. Caudell, Kamran A. Ahmed, T. Ström, Eric A. Mellon, Puja Venkat, Peter A.S. Johnstone, John A. Foekens, Jae Lee, Eduardo G. Moros, William S. Dalton, Steven A. Eschrich, Howard L. McLeod, Louis B. Harrison, Javier F. Torres–Roca - The Lancet Oncology 2016 cited by 469
- PARPi treatment enhances radiotherapy-induced ferroptosis and antitumor immune responses via the cGAS signaling pathway in colorectal cancer
Authors: Dongya Shen, Jia Luo, Ling Chen, Wenjuan Ma, Xiao‐Yuan Mao, Yu Zhang, Juyan Zheng, Yang Wang, Jielin Wan, Shiyu Wang, Jing Ouyang, Hanying Yi, Dongbo Liu, Weihua Huang, Wei Zhang, Zhaoqian Liu, Howard L. McLeod, Yijing He - Cancer Letters 2022 cited by 111
- Pharmacogenomics
Authors: Dan M. Roden, Howard L. McLeod, Mary V. Relling, Marc S. Williams, George A. Mensah, Josh F. Peterson, Sara L. Van Driest - The Lancet 2019 cited by 405
- Clonal haemopoiesis and therapy-related myeloid malignancies in elderly patients: a proof-of-concept, case-control study
Authors: Nancy Gillis, Markus Ball, Qing Zhang, Zhenjun Ma, YuLong Zhao, Sean Yoder, Maria E. Balasis, Tania Mesa, David A. Sallman, Jeffrey E. Lancet, Rami S. Komrokji, Alan F. List, Howard L. McLeod, Melissa Alsina, Rachid Baz, Kenneth H. Shain, Dana E. Rollison, Eric Padron - The Lancet Oncology 2016 cited by 313
- Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism
Authors: Godefridus J. Peters, Harold H.J. Backus, SJ Freemantle, Baukelien van Triest, Giovanni Codacci-Pisanelli, C.L. van der Wilt, Kees Smid, John Lunec, A. Hilary Calvert, Sharon Marsh, Howard L. McLeod, Elisabeth Bloemena, Sybren L. Meijer, Gerrit Jansen, C.J. van Groeningen, Herbert M. Pinedo - Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2002 cited by 430
- Mechanism-Based Inhibition of Cytochrome P450 3A4 by Therapeutic Drugs
Authors: Shu‐Feng Zhou, Sui Yung Chan, Boon Cher Goh, Eli Chan, Wei Duan, Min Huang, Howard L. McLeod - Clinical Pharmacokinetics 2005 cited by 510
- Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and Tamoxifen Therapy
Authors: Matthew P. Goetz, Katrin Sangkuhl, Henk‐Jan Guchelaar, Matthias Schwab, Michael A. Province, Michelle Whirl‐Carrillo, W. Fraser Symmans, Howard L. McLeod, Mark J. Ratain, Hitoshi Zembutsu, Andrea Gaedigk, Ron HN van Schaik, James N. Ingle, Kelly E. Caudle, Teri E. Klein - Clinical Pharmacology & Therapeutics 2018 cited by 324
- Genetic Markers of Toxicity From Capecitabine and Other Fluorouracil-Based Regimens: Investigation in the QUASAR2 Study, Systematic Review, and Meta-Analysis
Authors: Dan Rosmarin, Claire Palles, David N. Church, Enric Domingo, Angela Jones, Elaine Johnstone, Haitao Wang, Sharon Love, Patrick Julier, Claire Scudder, George Nicholson, Anna González‐Neira, Miguel Martín, Daniel J. Sargent, Erin Green, Howard L. McLeod, Ulrich M. Zanger, Matthias Schwab, Michael Braun, Michel Seymour, Lindsay C Thompson, Benjamin Lacas, Valérie Boige, Nuria Ribelles, Shoaib Afzal, Henrik Enghusen, Søren Astrup Jensen, Marie-Christine Etienne-Grimaldi, G. Milano, Mia Wadelius, Bengt Glimelius, Hans Garmo, Milena Gusella, Thierry Lecomte, Pierre Laurent‐Puig, Eva Martinez‐Balibrea, Rohini Sharma, Jesús García‐Foncillas, Zdeněk Kleibl, Alain Morel, Jean‐Pierre Pignon, Rachel Midgley, David Kerr, Ian D. Tomlinson - Journal of Clinical Oncology 2014 cited by 259
- The Genomic Landscape of Merkel Cell Carcinoma and Clinicogenomic Biomarkers of Response to Immune Checkpoint Inhibitor Therapy
Authors: Todd C. Knepper, Meagan Montesion, Jeffery S. Russell, Ethan S. Sokol, Garrett M. Frampton, Vincent A. Miller, Lee A. Albacker, Howard L. McLeod, Zeynep Eroglu, Nikhil I. Khushalani, Vernon K. Sondak, Jane L. Messina, Michael J. Schell, James A. DeCaprio, Kenneth Y. Tsai, Andrew S. Brohl - Clinical Cancer Research 2019 cited by 170
- When will clinical trials finally reflect diversity?
Authors: Todd C. Knepper, Howard L. McLeod - Nature 2018 cited by 147
- Pharmacogenomics — Drug Disposition, Drug Targets, and Side Effects
Authors: William E. Evans, Howard L. McLeod - New England Journal of Medicine 2003 cited by 1,768
- DPYD Testing: Time to Put Patient Safety First
Authors: Sharyn D. Baker, Susan E. Bates, Gabriel A. Brooks, William L. Dahut, Robert B. Diasio, Wafik S. El‐Deiry, William E. Evans, William D. Figg, Daniel L. Hertz, J. Kevin Hicks, Suneel Kamath, Pashtoon Murtaza Kasi, Todd C. Knepper, Howard L. McLeod, Peter H. O’Donnell, Mary V. Relling, Michelle A. Rudek, Tristan M. Sissung, D. Max Smith, Alex Sparreboom, Sandra M. Swain, Christine M. Walko - Journal of Clinical Oncology 2023 cited by 40
- PI3K/Akt/mTOR pathway as a target for cancer therapy
Authors: Daniel Morgensztern, Howard L. McLeod - Anti-Cancer Drugs 2005 cited by 466
- The Clinical Pharmacogenetics Implementation Consortium Guideline for SLCO1B1 and Simvastatin-Induced Myopathy: 2014 Update
Authors: Laura B. Ramsey, Samuel G. Johnson, Kelly E. Caudle, Cyrine E. Haidar, Deepak Voora, Russell A. Wilke, Whitney D. Maxwell, Howard L. McLeod, Ronald M. Krauss, D M Roden, QiPing Feng, Rhonda M. Cooper‐DeHoff, Li Gong, Teri E. Klein, Mia Wadelius, Mikko Niemi - Clinical Pharmacology & Therapeutics 2014 cited by 440
- Use of Pharmacogenetic and Clinical Factors to Predict the Therapeutic Dose of Warfarin
Authors: P. Lenzini, J. A. Johnson, Howard L. McLeod, M. J. Rieder, Brian F. Gage, L. Grosso, D. L. Veenstra, C. Eby, R. J. Glynn, D. Voora, T. Langaee, G. Grice, L. E. Farnett, Christina L. Aquilante, S. Marsh, P. M. Ridker, P. E. Milligan, A. E. Rettie, E. Deych, A. Barrett - Clinical Pharmacology & Therapeutics 2008 cited by 834
- Global implementation of genomic medicine: We are not alone
Authors: Teri A. Manolio, Marc Abramowicz, Fahd Al‐Mulla, Warwick P. Anderson, Rudi Balling, Adam C. Berger, Steven B. Bleyl, Aravinda Chakravarti, Wasun Chantratita, Rex L. Chisholm, Vajira H. W. Dissanayake, Michael Dunn, Victor J. Dzau, Bok‐Ghee Han, Tim Hubbard, Anne Kolbe, Bruce R. Korf, Michiaki Kubo, Paul Lasko, Erkki Leego, Surakameth Mahasirimongkol, Partha P. Majumdar, Gert Matthijs, Howard L. McLeod, Andres Metspalu, Pierre Meulien, Satoru Miyano, Yaakov Naparstek, P. Pearl O’Rourke, George P. Patrinos, Heidi L. Rehm, Mary V. Relling, Gad Rennert, Laura Lyman Rodriguez, Dan M. Roden, Alan R. Shuldiner, Sukdeb Sinha, Patrick Tan, Mats Ulfendahl, Robyn L. Ward, Marc S. Williams, John E.L. Wong, Eric D. Green, Geoffrey S. Ginsburg - Science Translational Medicine 2015 cited by 246
- Strategies for enzyme/prodrug cancer therapy.
Authors: Guo Xu, Howard L. McLeod - 2001 cited by 278
- Genomic Medicine: A Decade of Successes, Challenges, and Opportunities
Authors: Jeanette McCarthy, Howard L. McLeod, Geoffrey S. Ginsburg - Science Translational Medicine 2013 cited by 245
- Cytochrome P450 2C9-CYP2C9
Authors: Derek Van Booven, Sharon Marsh, Howard L. McLeod, Michelle Whirl‐Carrillo, Katrin Sangkuhl, Teri E. Klein, Russ B. Altman - Pharmacogenetics and Genomics 2010 cited by 239
- The National Cancer Institute Clinical Trials Planning Meeting for Prevention and Treatment of Chemotherapy-Induced Peripheral Neuropathy
Authors: Susan G. Dorsey, Ian R. Kleckner, Debra L. Barton, Karen M. Mustian, Ann M. O’Mara, Diane St. Germain, Guido Cavaletti, Suzanne C. Danhauer, Dawn L. Hershman, Andrea G. Hohmann, Ahmet Höke, Judith O. Hopkins, Katherine Patterson Kelly, Charles L. Loprinzi, Howard L. McLeod, Supriya G. Mohile, Judith A. Paice, Julia H. Rowland, Daniela Salvemini, Rosalind A. Segal, Elizabeth Smith, Worta McCaskill Stevens, Michelle C. Janelsins - JNCI Journal of the National Cancer Institute 2019 cited by 126
- Genomics and Drug Response
Authors: Liewei Wang, Howard L. McLeod, Richard M. Weinshilboum - New England Journal of Medicine 2011 cited by 614
- Carbamazepine, HLA-B*1502 and Risk of Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: US FDA Recommendations
Authors: P. Brent Ferrell, Howard L. McLeod - Pharmacogenomics 2008 cited by 417
