Jacques Pouysségur
Active 1977–2022
- 234
- Papers
- 58,342
- Citations
- 137
- h-index
- 234
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology57%
- Medicine28.8%
- Immunology and Microbiology5.1%
- Neuroscience3.2%
- Engineering2%
- Agricultural and Biological Sciences0.8%
- Other3.1%
Topics
- Cancer, Hypoxia, and Metabolism9.1%
- Autophagy in Disease and Therapy2.2%
- Mitochondrial Function and Pathology2%
- Protein Kinase Regulation and GTPase Signaling1.9%
- Epigenetics and DNA Methylation1.9%
- Immune cells in cancer1.9%
- Other81%
Coauthors
- Gilles Pagès36
- Edurne Berra23
- Nathalie M. Mazure21
- Gilles L’Allemain16
- M. Christiane Brahimi-Horn16
- Scott K. Parks15
- Jean‐Claude Chambard14
- Philippe Lenormand13
- S Paris13
- Danièle Roux12
- Milica Vučetić12
- Anne Brunet11
- Darren E. Richard11
- Ellen Van Obberghen‐Schilling11
- Johanna Chiche11
- Claude Sardet10
- Jérôme Durivault9
- Maša Ždralević9
- Ibtissam Marchiq8
- Yann Cormerais8
- A Franchi7
- Amandine Ginouvès7
- Laurent Counillon7
- S. Wakabayashi7
All papers
- LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells
Authors: Almut Brand, Katrin Singer, Gudrun E. Koehl, Marlene Kolitzus, Gabriele Schoenhammer, Annette Thiel, Carina Matos, Christina Bruß, Sebastian Klobuch, Katrin Peter, Michael Kastenberger, Christian Bogdan, Ulrike Schleicher, Andréas Mackensen, Evelyn Ullrich, Stefan Fichtner‐Feigl, Rebecca Kesselring, Matthias Mack, Uwe Ritter, Maximilian Schmid, Christian U. Blank, Katja Dettmer, Peter J. Oefner, Petra Hoffmann, Stefan Walenta, Edward K. Geissler, Jacques Pouysségur, Andreas Villunger, André Steven, Barbara Seliger, Stephan Schreml, Sebastian Haferkamp, Elisabeth Kohl, Sigrid Karrer, Mark Berneburg, Wolfgang Herr, Wolfgang Mueller‐Klieser, Kathrin Renner, Marina Kreutz - Cell Metabolism 2016 cited by 1,902
- Tumor Cell Metabolism: Cancer's Achilles' Heel
Authors: Guido Kroemer, Jacques Pouysségur - Cancer Cell 2008 cited by 2,291
- Tumor immunoevasion via acidosis-dependent induction of regulatory tumor-associated macrophages
Authors: Toszka Bohn, Steffen Rapp, Natascha Luther, Matthias Klein, Till-Julius Bruehl, Nobuhiko Kojima, Pamela Aranda Lopez, Jennifer Hahlbrock, Sabine Muth, Shogo Endo, Stefanie Pektor, Almut Brand, Kathrin Renner, Vanessa Popp, Katharina Gerlach, Dennis Vogel, Christina Lueckel, Danielle Arnold-Schild, Jacques Pouysségur, Marina Kreutz, Magdalena Huber, Jochem Koenig, Benno Weigmann, Hans Christian Probst, Esther von Stebut, Christian Becker, Hansjoerg Schild, Edgar Schmitt, Tobias Bopp - Nature Immunology 2018 cited by 444
- Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains
Authors: Grégory Bellot, Raquel García-Medina, Pierre Gounon, Johanna Chiche, Danièle Roux, Jacques Pouysségur, Nathalie M. Mazure - Molecular and Cellular Biology 2009 cited by 1,457
- Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy
Authors: Kathrin Renner, Christina Bruß, Annette Schnell, Gudrun E. Koehl, Holger M. Becker, Matthias Fante, Ayse N. Menevse, Nathalie Kauer, Raquel Blazquez, Lisa Hacker, Sonja-Maria Decking, Toszka Bohn, Stephanie Faerber, Katja Evert, Lisa Aigle, Sabine Amslinger, Maria Landa, Oscar Krijgsman, Elisa A. Rozeman, Christina Brummer, Peter J. Siska, Katrin Singer, Stefanie Pektor, Matthias Miederer, Katrin Peter, Eva Gottfried, Wolfgang Herr, Ibtisam Marchiq, Jacques Pouysségur, William Roush, SuFey Ong, Sarah Warren, Tobias Pukrop, Philipp Beckhove, Sven Arke Lang, Tobias Bopp, Christian U. Blank, John L. Cleveland, Peter J. Oefner, Katja Dettmer, Mark Selby, Marina Kreutz - Cell Reports 2019 cited by 298
- ‘Warburg effect’ controls tumor growth, bacterial, viral infections and immunity – Genetic deconstruction and therapeutic perspectives
Authors: Jacques Pouysségur, Ibtissam Marchiq, Scott K. Parks, Jérôme Durivault, Maša Ždralević, Milica Vučetić - Seminars in Cancer Biology 2022 cited by 170
- Double genetic disruption of lactate dehydrogenases A and B is required to ablate the “Warburg effect” restricting tumor growth to oxidative metabolism
Authors: Maša Ždralević, Almut Brand, Lorenza Di Ianni, Katja Dettmer, Jörg Reinders, Katrin Singer, Katrin Peter, Annette Schnell, Christina Bruß, Sonja-Maria Decking, Gudrun E. Koehl, Blanca Felipe‐Abrio, Jérôme Durivault, Pascale Bayer, Marie Evangelista, Thomas O’Brien, Peter J. Oefner, Kathrin Renner, Jacques Pouysségur, Marina Kreutz - Journal of Biological Chemistry 2018 cited by 255
- HIF prolyl‐hydroxylase 2 is the key oxygen sensor setting low steady‐state levels of HIF‐1α in normoxia
Authors: Edurne Berra, Emmanuel Benizri, Amandine Ginouvès, Véronique Volmat, Danièle Roux, Jacques Pouysségur - The EMBO Journal 2003 cited by 1,342
- Hypoxia signalling in cancer and approaches to enforce tumour regression
Authors: Jacques Pouysségur, Frédéric Dayan, Nathalie M. Mazure - Nature 2006 cited by 1,651
- Hypoxia and cancer
Authors: M. Christiane Brahimi-Horn, Johanna Chiche, Jacques Pouysségur - Journal of Molecular Medicine 2007 cited by 765
- Prolyl hydroxylase-1 negatively regulates IκB kinase-β, giving insight into hypoxia-induced NFκB activity
Authors: Eoin P. Cummins, Edurne Berra, Katrina M. Comerford, Amandine Ginouvès, Kathleen T. Fitzgerald, Fergal Seeballuck, Catherine Godson, Jens Erik Nielsen, Paul N. Moynagh, Jacques Pouysségur, Cormac T. Taylor - National Academy of Sciences, Proceedings of the National Academy of Sciences 2006 cited by 771
- Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer
Authors: Johanna Chiche, M. Christiane Brahimi-Horn, Jacques Pouysségur - Journal of Cellular and Molecular Medicine 2010 cited by 662
- Disrupting proton dynamics and energy metabolism for cancer therapy
Authors: Scott K. Parks, Johanna Chiche, Jacques Pouysségur - Nature reviews. Cancer 2013 cited by 600
- CD147 subunit of lactate/H + symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors
Authors: Renaud Le Floch, Johanna Chiche, Ibtissam Marchiq, Tanesha Naiken, Karine Ilc, Clare Murray, Susan E. Critchlow, Danièle Roux, Marie‐Pierre Simon, Jacques Pouysségur - National Academy of Sciences, Proceedings of the National Academy of Sciences 2011 cited by 413
- Genetic Ablation of the Cystine Transporter xCT in PDAC Cells Inhibits mTORC1, Growth, Survival, and Tumor Formation via Nutrient and Oxidative Stresses
Authors: Boutaina Daher, Scott K. Parks, Jérôme Durivault, Yann Cormerais, Hanane Baidarjad, Éric Tambutté, Jacques Pouysségur, Milica Vučetić - Cancer Research 2019 cited by 199
- The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition
Authors: Sylvain Meloche, Jacques Pouysségur - Oncogene 2007 cited by 1,104
- Hypoxia-induced autophagy: cell death or cell survival?
Authors: Nathalie M. Mazure, Jacques Pouysségur - Current Opinion in Cell Biology 2009 cited by 611
- Hypoxia, cancer metabolism and the therapeutic benefit of targeting lactate/H+ symporters
Authors: Ibtissam Marchiq, Jacques Pouysségur - Journal of Molecular Medicine 2015 cited by 296
- Warburg and Beyond: The Power of Mitochondrial Metabolism to Collaborate or Replace Fermentative Glycolysis in Cancer
Authors: Shamir Cassim, Milica Vučetić, Maša Ždralević, Jacques Pouysségur - Cancers 2020 cited by 171
- Hypoxia-Inducible Carbonic Anhydrase IX and XII Promote Tumor Cell Growth by Counteracting Acidosis through the Regulation of the Intracellular pH
Authors: Johanna Chiche, Karine Ilc, Julie Laferrière, Eric Trottier, Frédéric Dayan, Nathalie M. Mazure, M. Christiane Brahimi-Horn, Jacques Pouysségur - Cancer Research 2008 cited by 746
- ERK1 and ERK2 Map Kinases: Specific Roles or Functional Redundancy?
Authors: Roser Buscà, Jacques Pouysségur, Philippe Lenormand - Frontiers in Cell and Developmental Biology 2016 cited by 283
- Tumor Microenvironment: A Metabolic Player that Shapes the Immune Response
Authors: Shamir Cassim, Jacques Pouysségur - International Journal of Molecular Sciences 2019 cited by 187
- JunD Reduces Tumor Angiogenesis by Protecting Cells from Oxidative Stress
Authors: Damien Gerald, Edurne Berra, Yves‐Michel Frapart, Denise A. Chan, Amato J. Giaccia, Daniel Mansuy, Jacques Pouysségur, Moshé Yaniv, Fatima Mechta‐Grigoriou - Cell 2004 cited by 580
- NUPR1 inhibitor ZZW-115 induces ferroptosis in a mitochondria-dependent manner
Authors: Can Huang, Patricia Santofimia‐Castaño, Xi Liu, Yi Xia, Ling Peng, Célia Gotorbe, José L. Neira, Daolin Tang, Jacques Pouysségur, Juan Iovanna - Cell Death Discovery 2021 cited by 82
