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Joan Heller Brown

Active 1972–2025

Also published as
Joan Heller-Brown
123
Papers
22,915
Citations
95
h-index
121
i10-index

Citations

Citations per year for Joan Heller Brown1972: 2 citations1973: 5 citations1974: 9 citations1975: 6 citations1976: 5 citations1977: 5 citations1978: 5 citations1979: 2 citations1980: 5 citations1981: 6 citations1982: 5 citations1983: 7 citations1984: 9 citations1985: 31 citations1986: 55 citations1987: 69 citations1988: 59 citations1989: 36 citations1990: 45 citations1991: 48 citations1992: 36 citations1993: 55 citations1994: 66 citations1995: 72 citations1996: 84 citations1997: 95 citations1998: 204 citations1999: 234 citations2000: 294 citations2001: 276 citations2002: 204 citations2003: 240 citations2004: 270 citations2005: 196 citations2006: 212 citations2007: 219 citations2008: 198 citations2009: 228 citations2010: 207 citations2011: 267 citations2012: 215 citations2013: 254 citations2014: 254 citations2015: 200 citations2016: 172 citations2017: 126 citations2018: 145 citations2019: 458 citations2020: 581 citations2021: 490 citations2022: 414 citations2023: 255 citations2024: 395 citations2025: 162 citations

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 3,100 citing papers, 39.1% of this breakdownChina: 823 citing papers, 10.4% of this breakdownGermany: 519 citing papers, 6.6% of this breakdownUnited Kingdom: 481 citing papers, 6.1% of this breakdownJapan: 437 citing papers, 5.5% of this breakdownItaly: 290 citing papers, 3.7% of this breakdownCanada: 285 citing papers, 3.6% of this breakdownFrance: 213 citing papers, 2.7% of this breakdownNetherlands: 134 citing papers, 1.7% of this breakdownAustralia: 123 citing papers, 1.5% of this breakdownSpain: 111 citing papers, 1.4% of this breakdownSwitzerland: 99 citing papers, 1.2% of this breakdown
0%39.1%Other 16.5%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology52.2%
  • Medicine39.5%
  • Neuroscience3.7%
  • Immunology and Microbiology2%
  • Computer Science0.5%
  • Agricultural and Biological Sciences0.4%
  • Other1.7%

Topics

  • Protein Kinase Regulation and GTPase Signaling4.6%
  • Cardiac electrophysiology and arrhythmias4.5%
  • Ion channel regulation and function3.8%
  • Receptor Mechanisms and Signaling3.7%
  • Cardiac Fibrosis and Remodeling3.2%
  • Mitochondrial Function and Pathology2.8%
  • Other77.4%

Coauthors

All papers

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  1. Inflammation and NLRP3 Inflammasome Activation Initiated in Response to Pressure Overload by Ca 2+ /Calmodulin-Dependent Protein Kinase II δ Signaling in Cardiomyocytes Are Essential for Adverse Cardiac Remodeling

    Authors: Takeshi Suetomi, Andrew Willeford, Cameron S. Brand, Yoshitake Cho, Robert S. Ross, Shigeki Miyamoto, Joan Heller Brown - Circulation 2018 cited by 295

  2. Hyperglycemia Acutely Increases Cytosolic Reactive Oxygen Species via O -linked GlcNAcylation and CaMKII Activation in Mouse Ventricular Myocytes

    Authors: Shan Lü, Zhandi Liao, Xiyuan Lu, Dörthe M. Katschinski, Mark Mercola, Ju Chen, Joan Heller Brown, Jeffery D. Molkentin, Julie Bossuyt, Donald M. Bers - Circulation Research 2020 cited by 145

  3. SiglecF(HI) Marks Late‐Stage Neutrophils of the Infarcted Heart: A Single‐Cell Transcriptomic Analysis of Neutrophil Diversification

    Authors: David Calcagno, Claire Zhang, Avinash Toomu, Kenneth Huang, Van K. Ninh, Shigeki Miyamoto, Aaron D. Aguirre, Zhenxing Fu, Joan Heller Brown, Kevin R. King - Journal of the American Heart Association 2021 cited by 96

  4. RhoA signaling increases mitophagy and protects cardiomyocytes against ischemia by stabilizing PINK1 protein and recruiting Parkin to mitochondria

    Authors: Michelle Tu, Valerie P. Tan, Justin Yu, Raghav Tripathi, Zahna Bigham, Melissa Barlow, Jeffrey M. Smith, Joan Heller Brown, Shigeki Miyamoto - Cell Death and Differentiation 2022 cited by 49

  5. RhoA regulates Drp1 mediated mitochondrial fission through ROCK to protect cardiomyocytes

    Authors: Cameron S. Brand, Valerie P. Tan, Joan Heller Brown, Shigeki Miyamoto - Cellular Signalling 2018 cited by 89

  6. Ca2+/calmodulin-dependent protein kinase II regulates cardiac Na+ channels

    Authors: Stefan Wagner, Nataliya Dybkova, Eva Rasenack, Claudius Jacobshagen, Larissa Fabritz, Paulus Kirchhof, Sebastian K.G. Maier, Tong Zhang, Gerd Hasenfuß, Joan Heller Brown, Donald M. Bers, Lars S. Maier - Journal of Clinical Investigation 2006 cited by 554

  7. Cyclophilin D controls mitochondrial pore–dependent Ca2+ exchange, metabolic flexibility, and propensity for heart failure in mice

    Authors: John W. Elrod, Renee Wong, Shikha Mishra, Ronald J. Vagnozzi, Bhuvana Sakthievel, Sanjeewa A. Goonasekera, Jason Karch, Scott A. Gabel, John L. Farber, Thomas Force, Joan Heller Brown, Elizabeth Murphy, Jeffery D. Molkentin - Journal of Clinical Investigation 2010 cited by 370

  8. The δ C Isoform of CaMKII Is Activated in Cardiac Hypertrophy and Induces Dilated Cardiomyopathy and Heart Failure

    Authors: Tong Zhang, Lars S. Maier, Nancy D. Dalton, Shigeki Miyamoto, John Ross, Donald M. Bers, Joan Heller Brown - Circulation Research 2003 cited by 561

  9. CaMKII in myocardial hypertrophy and heart failure

    Authors: Mark E. Anderson, Joan Heller Brown, Donald M. Bers - Journal of Molecular and Cellular Cardiology 2011 cited by 467

  10. APJ acts as a dual receptor in cardiac hypertrophy

    Authors: Maria Cecilia Scimia, Cecilia Hurtado, Saugata Ray, Scott Metzler, Ke Wei, Jianming Wang, Chris E. Woods, Nicole H. Purcell, Daniele Catalucci, Takeshi Akasaka, Orlando F. Bueno, George P. Vlasuk, Perla Kaliman, Rolf Bodmer, Layton H. Smith, Euan A. Ashley, Mark Mercola, Joan Heller Brown, Pilar Ruiz‐Lozano - Nature 2012 cited by 242

  11. Inflammation in nonischemic heart disease: initiation by cardiomyocyte CaMKII and NLRP3 inflammasome signaling

    Authors: Takeshi Suetomi, Shigeki Miyamoto, Joan Heller Brown - American Journal of Physiology-Heart and Circulatory Physiology 2019 cited by 96

  12. Requirement for Ca2+/calmodulin–dependent kinase II in the transition from pressure overload–induced cardiac hypertrophy to heart failure in mice

    Authors: Haiyun Ling, Tong Zhang, Laëtitia Pereira, Christopher K. Means, Hongqiang Cheng, Yusu Gu, Nancy D. Dalton, Kirk L. Peterson, Ju Chen, Donald M. Bers, Joan Heller Brown - Journal of Clinical Investigation 2009 cited by 383

  13. Akt mediates mitochondrial protection in cardiomyocytes through phosphorylation of mitochondrial hexokinase-II

    Authors: Shigeki Miyamoto, Anne N. Murphy, Joan Heller Brown - Cell Death and Differentiation 2007 cited by 333

  14. CaMKIIδ-mediated inflammatory gene expression and inflammasome activation in cardiomyocytes initiate inflammation and induce fibrosis

    Authors: Andrew Willeford, Takeshi Suetomi, Audrey Nickle, Hal M. Hoffman, Shigeki Miyamoto, Joan Heller Brown - JCI Insight 2018 cited by 127

  15. Chronic inhalation of e-cigarette vapor containing nicotine disrupts airway barrier function and induces systemic inflammation and multiorgan fibrosis in mice

    Authors: Laura E. Crotty Alexander, Christopher A. Drummond, Mark Hepokoski, Denzil P. Mathew, Alexander Moshensky, Andrew Willeford, Soumita Das, Prabhleen Singh, Zach Yong, Jasmine H. Lee, Kevin Vega, Ashley Du, John H. Shin, Christian Javier, Jiang Tian, Joan Heller Brown, Ellen C. Breen - American Journal of Physiology-Regulatory, American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 2018 cited by 225

  16. Ca 2+ /Calmodulin-Dependent Protein Kinase II δ Mediates Myocardial Ischemia/Reperfusion Injury Through Nuclear Factor-κB

    Authors: Haiyun Ling, Charles B.B. Gray, Alexander C. Zambon, Michael Grimm, Yusu Gu, Nancy D. Dalton, Nicole H. Purcell, Kirk L. Peterson, Joan Heller Brown - Circulation Research 2013 cited by 179

  17. Effects of mango and mint pod-based e-cigarette aerosol inhalation on inflammatory states of the brain, lung, heart, and colon in mice

    Authors: Alex Moshensky, Cameron S Brand, Hasan Alhaddad, John Shin, Jorge A Masso-Silva, Ira Advani, Deepti Gunge, Aditi Sharma, Sagar Mehta, Arya Jahan, Sedtavut Nilaad, Jarod Olay, Wanjun Gu, Tatum Simonson, Daniyah Almarghalani, Josephine Pham, Samantha Perera, Kenneth Park, Rita Al-Kolla, Hoyoung Moon, Soumita Das, Min Kwang Byun, Zahoor Shah, Youssef Sari, Joan Heller Brown, Laura E Crotty Alexander - eLife 2022 cited by 50

  18. MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice

    Authors: Denghong Zhang, Riccardo Contu, Michael V.G. Latronico, Jian Ling Zhang, Roberto Rizzi, Daniele Catalucci, Shigeki Miyamoto, Katherine Huang, Marcello Ceci, Yusu Gu, Nancy D. Dalton, Kirk L. Peterson, Kun‐Liang Guan, Joan Heller Brown, Chen Ju, Nahum Sonenberg, Gianluigi Condorelli - Journal of Clinical Investigation 2010 cited by 335

  19. An FHL1-containing complex within the cardiomyocyte sarcomere mediates hypertrophic biomechanical stress responses in mice

    Authors: Farah Sheikh, Anna Raskin, Pao-Hsien Chu, Stephan Lange, Andrea A. Domenighetti, Ming Zheng, Xingqun Liang, Tong Zhang, Toshitaka Yajima, Yusu Gu, Nancy D. Dalton, Sushil K. Mahata, Gerald W. Dorn, Joan Heller-Brown, Kirk L. Peterson, Jeffrey H. Omens, Andrew D. McCulloch, Ju Chen - Journal of Clinical Investigation 2008 cited by 253

  20. Sphingosine-1-phosphate receptor signalling in the heart

    Authors: Chris K. Means, Joan Heller Brown - Cardiovascular Research 2008 cited by 236

  21. Sphingosine 1-phosphate S1P2 and S1P3 receptor-mediated Akt activation protects against in vivo myocardial ischemia-reperfusion injury

    Authors: Christopher K. Means, Chun-Yang Xiao, Zhuangjie Li, Tong Zhang, Jeffrey H. Omens, Isao Ishii, Jerold Chun, Joan Heller Brown - American Journal of Physiology-Heart and Circulatory Physiology 2007 cited by 217

  22. CaMKIIδC Drives Early Adaptive Ca 2+ Change and Late Eccentric Cardiac Hypertrophy

    Authors: Senka Ljubojević-Holzer, Anthony W. Herren, Nataša Djalinac, Julia Voglhuber, Stefano Morotti, Michael Holzer, Brent M. Wood, Mahmoud Abdellatif, Ingrid Matzer, Michael Sacherer, Snježana Radulović, Markus Wallner, Milan Ivanov, Stefan Wagner, Samuel Sossalla, Dirk von Lewinski, Burkert Pieske, Joan Heller Brown, Simon Sedej, Julie Bossuyt, Donald M. Bers - Circulation Research 2020 cited by 59

  23. β-Adrenergic receptor signaling in the heart: Role of CaMKII

    Authors: Michael Grimm, Joan Heller Brown - Journal of Molecular and Cellular Cardiology 2009 cited by 240

  24. Sphingosine 1-phosphate receptor 3 and RhoA signaling mediate inflammatory gene expression in astrocytes

    Authors: Stephanie S. Dusaban, Jerold Chun, Hugh Rosen, Nicole H. Purcell, Joan Heller Brown - Journal of Neuroinflammation 2017 cited by 105