Joel L. Sussman
Active 1972–2025
- 151
- Papers
- 31,722
- Citations
- 91
- h-index
- 148
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology47.8%
- Medicine31.3%
- Computer Science4.7%
- Materials Science3.9%
- Agricultural and Biological Sciences3.2%
- Chemistry2.9%
- Other6.2%
Topics
- Cholinesterase and Neurodegenerative Diseases9.3%
- Computational Drug Discovery Methods8.8%
- Protein Structure and Dynamics6.3%
- RNA and protein synthesis mechanisms5.1%
- Enzyme Structure and Function4.1%
- Enzyme Catalysis and Immobilization2.1%
- Other64.3%
Coauthors
- Israel Silman98
- Michal Harel27
- Harry M. Greenblatt17
- Jaime Prilusky11
- Martin H. Weik10
- Gitay Kryger9
- Hay Dvir9
- Jacques‐Philippe Colletier9
- Orly Dym9
- Yechun Xu9
- Anthony H. Futerman8
- Hualiang Jiang8
- Jean Massoulié8
- Clifford E. Felder7
- Dan S. Tawfik7
- Lilly Toker7
- Charles B. Millard6
- Felix Frolow6
- S. H. Kim6
- Yacov Ashani6
- Avigdor Shafferman5
- Aviv Paz5
- Dawn M. Wong5
- Mia L. Raves5
All papers
- Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability
Authors: Adi Goldenzweig, Moshe Goldsmith, Shannon E. Hill, Or Gertman, Paola Laurino, Yacov Ashani, Orly Dym, Tamar Unger, Shira Albeck, Jaime Prilusky, Raquel L. Lieberman, Amir Aharoni, Israel Silman, Joel L. Sussman, Dan S. Tawfik, Sarel J. Fleishman - Molecular Cell 2016 cited by 584
- Acetylcholinesterase: From 3D structure to function
Authors: Hay Dvir, Israel Silman, Michal Harel, Terrone L. Rosenberry, Joel L. Sussman - Chemico-Biological Interactions 2010 cited by 778
- Protein Data Bank (PDB): Database of Three-Dimensional Structural Information of Biological Macromolecules
Authors: Joel L. Sussman, Dawei Lin, Jiansheng Jiang, N. O. Manning, Jaime Prilusky, Otto Ritter, Enrique E. Abola - Acta Crystallographica Section D Biological Crystallography 1998 cited by 773
- Atomic Structure of Acetylcholinesterase from Torpedo californica : A Prototypic Acetylcholine-Binding Protein
Authors: Joel L. Sussman, Michal Harel, Felix Frolow, Christian Oefner, Adrian Goldman, Lilly Toker, Israel Silman - Science 1991 cited by 2,712
- Function and structure of inherently disordered proteins
Authors: A. Keith Dunker, Israel Silman, Vladimir N. Uversky, Joel L. Sussman - Current Opinion in Structural Biology 2008 cited by 966
- The α/β hydrolase fold
Authors: David L. Ollis, Eong Cheah, Mirosław Cygler, Bauke W. Dijkstra, Felix Frolow, Sybille Franken, Michal Harel, S. Jamse Remington, Israel Silman, Joseph D. Schrag, Joel L. Sussman, Koen H. G. Verschueren, Adrian Goldman - Protein Engineering Design and Selection 1992 cited by 2,108
- Acetylcholinesterase: How is structure related to function?
Authors: Israel Silman, Joel L. Sussman - Chemico-Biological Interactions 2008 cited by 262
- What’s in a name? Why these proteins are intrinsically disordered
Authors: A. Keith Dunker, M. Madan Babu, Elisar Barbar, Martin Blackledge, Sarah E. Bondos, Zsuzsanna Dosztányi, H. Jane Dyson, Julie D. Forman‐Kay, Mónika Fuxreiter, Jörg Gsponer, Kyou‐Hoon Han, David T. Jones, Sonia Longhi, Steven J. Metallo, Ken Nishikawa, Ruth Nussinov, Zoran Obradović, Rohit V. Pappu, Burkhard Rost, Philipp Selenko, Vinod Subramaniam, Joel L. Sussman, Péter Tompa, Vladimir N. Uversky - Intrinsically Disordered Proteins 2013 cited by 306
- Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase.
Authors: Michal Harel, Isabelle J. Schalk, Laurence Ehret‐Sabatier, Françoise Bouet, Maurice Goeldner, C. Hirth, Paul H. Axelsen, Israel Silman, Joel L. Sussman - National Academy of Sciences, Proceedings of the National Academy of Sciences 1993 cited by 903
- Structure of acetylcholinesterase complexed with E2020 (Aricept®): implications for the design of new anti-Alzheimer drugs
Authors: Gitay Kryger, Israel Silman, Joel L. Sussman - Structure 1999 cited by 747
- JSmol and the Next‐Generation Web‐Based Representation of 3D Molecular Structure as Applied to Proteopedia
Authors: Robert M. Hanson, Jaime Prilusky, Zhou Renjian, Takanori Nakane, Joel L. Sussman - Israel Journal of Chemistry 2013 cited by 263
- Computational Studies on Acetylcholinesterases
Authors: Yechun Xu, Shanmei Cheng, Joel L. Sussman, Israel Silman, Hualiang Jiang - Molecules 2017 cited by 66
- Three-Dimensional Tertiary Structure of Yeast Phenylalanine Transfer RNA
Authors: S. H. Kim, F. L. Suddath, Gary J. Quigley, Alexander McPherson, Joel L. Sussman, A. H. J. Wang, Nadrian C. Seeman, Alexander Rich - Science 1974 cited by 993
- Acetylcholinesterase: ‘classical’ and ‘non-classical’ functions and pharmacology
Authors: Israel Silman, Joel L. Sussman - Current Opinion in Pharmacology 2005 cited by 519
- Structural insights into substrate traffic and inhibition in acetylcholinesterase
Authors: Jacques‐Philippe Colletier, Didier Fournier, Harry M. Greenblatt, Jure Stojan, Joel L. Sussman, Giuseppe Zaccaı̈, Israel Silman, Martin H. Weik - The EMBO Journal 2006 cited by 202
- X‐ray structure of human acid‐β‐glucosidase, the defective enzyme in Gaucher disease
Authors: Hay Dvir, Michal Harel, Andrew A. McCarthy, Lilly Toker, Israel Silman, Anthony H. Futerman, Joel L. Sussman - EMBO Reports 2003 cited by 274
- Three-dimensional structures of avidin and the avidin-biotin complex.
Authors: Oded Livnah, Edward A. Bayer, Meir Wilchek, Joel L. Sussman - National Academy of Sciences, Proceedings of the National Academy of Sciences 1993 cited by 652
- Production of glucocerebrosidase with terminal mannose glycans for enzyme replacement therapy of Gaucher's disease using a plant cell system
Authors: Yoseph Shaaltiel, Daniel Bartfeld, Sharon Hashmueli, Gideon Baum, Einat Brill‐Almon, Gad Galili, Orly Dym, Swetlana Boldin‐Adamsky, Israel Silman, Joel L. Sussman, Anthony H. Futerman, David Aviezer - Plant Biotechnology Journal 2007 cited by 429
- Kinetic and Structural Studies on the Interaction of Cholinesterases with the Anti-Alzheimer Drug Rivastigmine,
Authors: P. Bar-On, Charles B. Millard, Michal Harel, Hay Dvir, Albert Enz, Joel L. Sussman, Israel Silman - Biochemistry 2002 cited by 319
- Context‐dependent resistance to proteolysis of intrinsically disordered proteins
Authors: Marcin J. Suskiewicz, Joel L. Sussman, Israel Silman, Yosef Shaul - Protein Science 2011 cited by 100
- Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3
Authors: Killian Oukoloff, Nicolas Coquelle, Manuela Bartolini, Marina Naldi, Rémy Le Guével, Stéphane Bach, Béatrice Josselin, Sandrine Ruchaud, Marco Catto, Leonardo Pisani, Nunzio Denora, Rosa Maria Iacobazzi, Israel Silman, Joel L. Sussman, Frédéric Buron, Jacques‐Philippe Colletier, Ludovic Jean, Sylvain Routier, Pierre‐Yves Renard - European Journal of Medicinal Chemistry 2019 cited by 65
- Structure of acetylcholinesterase complexed with (−)‐galanthamine at 2.3 Å resolution
Authors: Harry M. Greenblatt, Gitay Kryger, T. Lewis, Israel Silman, Joel L. Sussman - FEBS Letters 1999 cited by 307
- Flexibility of Aromatic Residues in the Active-Site Gorge of Acetylcholinesterase: X-ray versus Molecular Dynamics
Authors: Yechun Xu, Jacques‐Philippe Colletier, Martin H. Weik, Hualiang Jiang, John Moult, Israel Silman, Joel L. Sussman - Biophysical Journal 2008 cited by 123
- The future of integrated structural biology
Authors: Harald Schwalbe, Pauline Audergon, Natalie Haley, Claudia Alen Amaro, Jon Agirre, Marc Baldus, Lucia Banci, Wolfgang Baumeister, Martin Blackledge, J.M. Carazo, Kristina Djinović‐Carugo, Patrick H. N. Celie, Isabella C. Felli, Darren J. Hart, Thomas Hauß, L. Lehtiö, Kresten Lindorff‐Larsen, José Juan González Márquez, André Matagne, Roberta Pierattelli, Antonio Rosato, Frank Sobott, Sridhar Sreeramulu, Jan Steyaert, Joel L. Sussman, Lukáš Trantı́rek, M.S. Weiss, Matthias Wilmanns - Structure 2024 cited by 40
