John C. H. Spence

Active 1978–2024

80
Papers
19,935
Citations
68
h-index
77
i10-index

Citations

Citations per year for John C. H. Spence1961: 1 citations1968: 1 citations1982: 1 citations1984: 3 citations1985: 2 citations1986: 3 citations1987: 1 citations1988: 1 citations1989: 1 citations1991: 2 citations1992: 3 citations1993: 1 citations1994: 1 citations1995: 1 citations1996: 3 citations1997: 3 citations1998: 3 citations1999: 4 citations2000: 7 citations2001: 8 citations2002: 3 citations2003: 5 citations2004: 14 citations2005: 16 citations2006: 26 citations2007: 41 citations2008: 28 citations2009: 52 citations2010: 46 citations2011: 71 citations2012: 193 citations2013: 132 citations2014: 268 citations2015: 301 citations2016: 325 citations2017: 341 citations2018: 172 citations2019: 799 citations2020: 617 citations2021: 526 citations2022: 307 citations2023: 184 citations2024: 327 citations2025: 128 citations2026: 3 citations1962–1967: no citations, so these years are not shown1969–1981: no citations, so these years are not shown1983: no citations, so this year is not shown1990: no citations, so this year is not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 1,083 citing papers, 25.8% of this breakdownGermany: 576 citing papers, 13.7% of this breakdownUnited Kingdom: 317 citing papers, 7.6% of this breakdownChina: 284 citing papers, 6.8% of this breakdownFrance: 200 citing papers, 4.8% of this breakdownJapan: 184 citing papers, 4.4% of this breakdownSwitzerland: 163 citing papers, 3.9% of this breakdownSweden: 161 citing papers, 3.8% of this breakdownAustralia: 137 citing papers, 3.3% of this breakdownCanada: 89 citing papers, 2.1% of this breakdownNetherlands: 87 citing papers, 2.1% of this breakdownSouth Korea: 85 citing papers, 2% of this breakdown
0%25.8%Other 19.7%

Fields

  • Biochemistry, Genetics and Molecular Biology39.4%
  • Physics and Astronomy21%
  • Materials Science17.4%
  • Neuroscience5.7%
  • Medicine4.7%
  • Engineering3.4%
  • Other8.4%

Topics

  • Advanced Electron Microscopy Techniques and Applications11%
  • Advanced X-ray Imaging Techniques8.1%
  • Enzyme Structure and Function6.6%
  • Receptor Mechanisms and Signaling5.4%
  • Protein Structure and Dynamics3.6%
  • Photosynthetic Processes and Mechanisms3.3%
  • Other62%

Coauthors

All papers

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  1. Femtosecond X-ray protein nanocrystallography

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , J. Krzywiński, Christoph Bostedt, S. Bajt, Lars Gumprecht, Benedikt Rudek, Benjamin Erk, Carlo Schmidt, André Hömke, Christian Reich, Daniel Pietschner, L. Strüder, Günter Hauser, H. Gorke, J. Ullrich, Sven Herrmann, Gerhard Schäller, F. Schopper, H. Soltau, K.-U. Kühnel, M. Messerschmidt, John D. Bozek, Stefan P. Hau‐Riege, Matthias Frank, Christina Y. Hampton, Raymond G. Sierra, D. Starodub, Garth J. Williams, János Hajdu, Nicuşor Tı̂mneanu, M. Seibert, Jakob Andreasson, Andrea Rocker, H. Olof Jönsson, Martin Svenda, Stephan Stern, Karol Nass, Robert Andritschke, Claus-Dieter Schröter, Faton Krasniqi, Mario Bott, K. E. Schmidt, Xiaoyu Wang, Ingo Grotjohann, James M. Holton, Thomas R. M. Barends, Richard Neutze, Stefano Marchesini, Raimund Fromme, Sebastian Schorb, Daniela Rupp, M. Adolph, Tais Gorkhover, Inger Andersson, H. Hirsemann, Guillaume Potdevin, H. Graafsma, Björn Nilsson, John C. H. Spence - Nature 2011 cited by 2,122

  2. Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Cornelius Gati, Nadia A. Zatsepin, Dingjie Wang, Daniel James, Shibom Basu, Shatabdi Roy-Chowdhury, Chelsie E. Conrad, Jesse Coe, Haiguang Liu, Stella Lisova, Christopher Kupitz, Ingo Grotjohann, Raimund Fromme, Yi Jiang, Minjia Tan, Huaiyu Yang, Jun Li, Meitian Wang, Zhong Zheng, Dianfan Li, Nicole Howe, Yingming Zhao, Jörg Standfuss, Kay Diederichs, Yuhui Dong, Clinton S. Potter, Bridget Carragher, Martin Caffrey, Hualiang Jiang, Henry N. Chapman, John C. H. Spence, Petra Fromme, Uwe Weierstall, Oliver P. Ernst, Vsevolod Katritch, Vsevolod V. Gurevich, Patrick R. Griffin, Wayne L. Hubbell, Raymond C. Stevens, Vadim Cherezov, Karsten Melcher, H. Eric Xu - Nature 2015 cited by 837

  3. X-ray image reconstruction from a diffraction pattern alone

    Authors: , , , , , , , - Physical review. B, Condensed matter 2003 cited by 874

  4. High-Resolution Protein Structure Determination by Serial Femtosecond Crystallography

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , David Arnlund, Michael J. Bogan, Carl Caleman, Raimund Fromme, Christina Y. Hampton, Mark S. Hunter, Linda C. Johansson, Gergely Katona, Christopher Kupitz, Mengning Liang, Andrew V. Martin, Karol Nass, Lars Redecke, Francesco Stellato, Nicuşor Tı̂mneanu, Dingjie Wang, Nadia A. Zatsepin, Donald W. Schafer, James Defever, Richard Neutze, Petra Fromme, John C. H. Spence, Henry N. Chapman, Ilme Schlichting - Science 2012 cited by 869

  5. Femtosecond structural dynamics drives the trans/cis isomerization in photoactive yellow protein

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Raimund Fromme, V. Šrajer, Robert Henning, John C. H. Spence, A. Ourmazd, Peter Schwander, Uwe Weierstall, Matthias Frank, Petra Fromme, Anton Barty, Henry N. Chapman, Keith Moffat, Jasper J. van Thor, Marius Schmidt - Science 2016 cited by 451

  6. Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Xiaobing Zuo, Xinhua Ji, Anton Barty, Nadia A. Zatsepin, Henry N. Chapman, John C. H. Spence, Sarah A. Woodson, Ying-Jun Wang - Nature 2016 cited by 312

  7. Time-resolved serial crystallography captures high-resolution intermediates of photoactive yellow protein

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Keith Moffat, Jasper J. van Thor, John C. H. Spence, Petra Fromme, Henry N. Chapman, Marius Schmidt - Science 2014 cited by 512

  8. Enzyme intermediates captured “on the fly” by mix-and-inject serial crystallography

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Thomas D. Grant, Valerio Mariani, Garrett Nelson, Ganesh Subramanian, Euiyoung Bae, Raimund Fromme, Russell Fung, Peter Schwander, Matthias Frank, Thomas A. White, Uwe Weierstall, Nadia A. Zatsepin, John C. H. Spence, Petra Fromme, Henry N. Chapman, Lois Pollack, L.W. Tremblay, A. Ourmazd, George N. Phillips, Marius Schmidt - BMC Biology 2018 cited by 166

  9. Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Kenneth R. Beyerlein, Raymond C. Stevens, Dianfan Li, Syed Tasadaque Ali Shah, Nicole Howe, Martin Caffrey, Vadim Cherezov - Nature Communications 2014 cited by 595

  10. Observation of substrate diffusion and ligand binding in enzyme crystals using high-repetition-rate mix-and-inject serial crystallography

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , John C. H. Spence, Peter Schwander, Anton Barty, Henry N. Chapman, Petra Fromme, Adrian P. Mancuso⋈, George N. Phillips, Richard Bean, Lois Pollack, Marius Schmidt - IUCrJ 2021 cited by 84

  11. High-resolution ab initio three-dimensional x-ray diffraction microscopy

    Authors: , , , , , , , , , , , , , - Journal of the Optical Society of America A 2006 cited by 581

  12. An assessment of the resolution limitation due to radiation-damage in X-ray diffraction microscopy

    Authors: , , , , , , , , , , , , , - Journal of Electron Spectroscopy and Related Phenomena 2008 cited by 517

  13. Structural basis for bifunctional peptide recognition at human δ-opioid receptor

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Peter W. Schiller, Bryan L. Roth, Steven Ballet, Vsevolod Katritch, Raymond C. Stevens, Vadim Cherezov - Nature Structural & Molecular Biology 2015 cited by 179

  14. Single mimivirus particles intercepted and imaged with an X-ray laser

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , J. Krzywiński, Garth J. Williams, Keith O. Hodgson, Michael J. Bogan, Christina Y. Hampton, Raymond G. Sierra, D. Starodub, Inger Andersson, S. Bajt, Miriam Barthelmeß, John C. H. Spence, Petra Fromme, Uwe Weierstall, Richard A. Kirian, Mark S. Hunter, R. Bruce Doak, Stefano Marchesini, Stefan P. Hau‐Riege, Matthias Frank, Robert L. Shoeman, Lukas Lomb, Sascha W. Epp, Robert Hartmann, Daniel Rolles, Artem Rudenko, Carlo Schmidt, L. Foucar, Nils Kimmel, P. Holl, Benedikt Rudek, Benjamin Erk, André Hömke, Christian Reich, Daniel Pietschner, G. Weidenspointner, L. Strüder, Günter Hauser, H. Gorke, J. Ullrich, Ilme Schlichting, Sven Herrmann, Gerhard Schäller, F. Schopper, H. Soltau, K. U. Kühnel, Robert Andritschke, Claus-Dieter Schröter, Faton Krasniqi, Mario Bott, Sebastian Schorb, Daniela Rupp, M. Adolph, Tais Gorkhover, H. Hirsemann, Guillaume Potdevin, H. Graafsma, Björn Nilsson, Henry N. Chapman, János Hajdu - Nature 2011 cited by 915

  15. Serial time-resolved crystallography of photosystem II using a femtosecond X-ray laser

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Stefan P. Hau‐Riege, Stephan Kassemeyer, Hartawan Laksmono, Mengning Liang, Lukas Lomb, Stefano Marchesini, Andrew V. Martin, M. Messerschmidt, Despina Milathianaki, Karol Nass, Alexandra Ros, Shatabdi Roy-Chowdhury, K. E. Schmidt, M. Seibert, Jan Steinbrener, Francesco Stellato, Li‐Fen Yan, Chunhong Yoon, Thomas A. Moore, Ana L. Moore, Yulia Pushkar, Garth J. Williams, Sébastien Boutet, R. Bruce Doak, Uwe Weierstall, Matthias Frank, Henry N. Chapman, John C. H. Spence, Petra Fromme - Nature 2014 cited by 469

  16. Visualizing a protein quake with time-resolved X-ray scattering at a free-electron laser

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Mengning Liang, Andrew V. Martin, M. Nielsen, M. Messerschmidt, M. Seibert, Jennie Sjöhamn, Francesco Stellato, Uwe Weierstall, Nadia A. Zatsepin, John C. H. Spence, Petra Fromme, Ilme Schlichting, Sébastien Boutet, Gerrit Groenhof, Henry N. Chapman, Richard Neutze - Nature Methods 2014 cited by 208

  17. Double-flow focused liquid injector for efficient serial femtosecond crystallography

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Grega Belšak, Marjan Maček, Fabian Wilde, Andrew Aquila, Sébastien Boutet, Mengning Liang, Mark S. Hunter, Patrick Scheerer, John D. Lipscomb, Uwe Weierstall, Roger D. Kornberg, John C. H. Spence, Lois Pollack, Henry N. Chapman, S. Bajt - Scientific Reports 2017 cited by 134

  18. Gas dynamic virtual nozzle for generation of microscopic droplet streams

    Authors: , , , , , , - Journal of Physics D Applied Physics 2008 cited by 503

  19. Natively Inhibited Trypanosoma brucei Cathepsin B Structure Determined by Using an X-ray Laser

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Richard A. Kirian, Rudolf Koopmann, Chris Kupitz, Lukas Lomb, Andrew V. Martin, Stefan Mogk, Richard Neutze, Robert L. Shoeman, Jan Steinbrener, Nicuşor Tı̂mneanu, Dingjie Wang, Uwe Weierstall, Nadia A. Zatsepin, John C. H. Spence, Petra Fromme, Ilme Schlichting, Michael Duszenko, Christian Betzel, Henry N. Chapman - Science 2012 cited by 437

  20. Lipidic cubic phase serial millisecond crystallography using synchrotron radiation

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , - IUCrJ 2015 cited by 226

  21. Structural enzymology using X-ray free electron lasers

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Nirupa Nagaratnam, Domingo Meza, Raimund Fromme, Shibom Basu, Matthias Frank, Thomas A. White, Anton Barty, S. Bajt, Oleksandr Yefanov, Henry N. Chapman, Nadia A. Zatsepin, Garrett Nelson, Uwe Weierstall, John C. H. Spence, Peter Schwander, Lois Pollack, Petra Fromme, A. Ourmazd, George N. Phillips, Marius Schmidt - Structural Dynamics 2016 cited by 121

  22. High-viscosity injector-based pink-beam serial crystallography of microcrystals at a synchrotron radiation source

    Authors: , , , , , , , , , , , , , , , , , , , , - IUCrJ 2019 cited by 62

  23. Serial Femtosecond Crystallography of G Protein–Coupled Receptors

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , John C. H. Spence, Raymond C. Stevens, Vadim Cherezov - Science 2013 cited by 458

  24. In vivo protein crystallization opens new routes in structural biology

    Authors: , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Christina Y. Hampton, Andreas Hartmann, Robert Hartmann, Günter Hauser, H. Hirsemann, P. Holl, Mark S. Hunter, Stephan Kassemeyer, Richard A. Kirian, Lukas Lomb, Filipe R. N. C. Maia, Nils Kimmel, Andrew V. Martin, M. Messerschmidt, Christian Reich, Daniel Rolles, Benedikt Rudek, Artem Rudenko, Ilme Schlichting, Joachim Schulz, M. Seibert, Robert L. Shoeman, Raymond G. Sierra, H. Soltau, Stephan Stern, L. Strüder, Nicuşor Tı̂mneanu, J. Ullrich, Xiaoyu Wang, G. Weidenspointner, Uwe Weierstall, Garth J. Williams, C. Wunderer, Petra Fromme, John C. H. Spence, Thilo Stehle, Henry N. Chapman, Christian Betzel, Michael Duszenko - Nature Methods 2012 cited by 213