John M. Denu
Active 1994–2025
- Also published as
- John M Denu
- 126
- Papers
- 27,293
- Citations
- 88
- h-index
- 124
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology50.2%
- Medicine36.2%
- Neuroscience5.2%
- Agricultural and Biological Sciences2.3%
- Immunology and Microbiology2.3%
- Chemistry1.2%
- Other2.6%
Topics
- Sirtuins and Resveratrol in Medicine8.4%
- Epigenetics and DNA Methylation4.5%
- Autophagy in Disease and Therapy3.7%
- Histone Deacetylase Inhibitors Research3.6%
- Adipose Tissue and Metabolism3.2%
- Genomics and Chromatin Dynamics2.8%
- Other73.8%
Coauthors
- Brian C. Smith12
- Kirk Tanner9
- Alexis J. Lawton8
- Jack E. Dixon8
- Luigi Puglielli8
- William C. Hallows8
- Jessica L. Feldman7
- Kristin E. Dittenhafer‐Reed7
- Spencer A. Haws7
- Wei Yu7
- Joshua J. Coon6
- Kimberly A. Krautkramer6
- Mark A. Klein6
- Brittany N. Albaugh5
- Catherine A. Musselman5
- Christopher Berndsen5
- Dudley W. Lamming5
- Federico E. Rey5
- Jessica Han5
- Jing Fan5
- Josue Baeza5
- Michael J. Rigby5
- Michael J. Smallegan5
- Michael Jackson5
All papers
- Interactions between Roseburia intestinalis and diet modulate atherogenesis in a murine model
Authors: Kazuyuki Kasahara, Kimberly A. Krautkramer, Elin Org, Kymberleigh A. Romano, Robert L. Kerby, Eugenio I. Vivas, Margarete Mehrabian, John M. Denu, Fredrik Bäckhed, Aldons J. Lusis, Federico E. Rey - Nature Microbiology 2018 cited by 553
- Diet-Microbiota Interactions Mediate Global Epigenetic Programming in Multiple Host Tissues
Authors: Kimberly A. Krautkramer, Julia H. Kreznar, Kymberleigh A. Romano, Eugenio I. Vivas, Gregory A. Barrett‐Wilt, Mary E. Rabaglia, Mark P. Keller, Alan Attie, Federico E. Rey, John M. Denu - Molecular Cell 2016 cited by 602
- Histone Acetyltransferases
Authors: Sharon Y. Roth, John M. Denu, C. David Allis - Annual Review of Biochemistry 2001 cited by 1,841
- Short-chain fatty acids activate acetyltransferase p300
Authors: Sydney P Thomas, John M Denu - eLife 2021 cited by 134
- Circadian Clock NAD + Cycle Drives Mitochondrial Oxidative Metabolism in Mice
Authors: Clara Bien Peek, Alison H. Affinati, Kathryn Moynihan Ramsey, Hsin-Yu Kuo, Wei Yu, Laura A. Sena, Olga Ilkayeva, Biliana Marcheva, Yumiko Kobayashi, Chiaki Omura, Daniel C. Levine, David J. Bacsik, David Gius, Christopher B. Newgard, Eric S. Goetzman, Navdeep S. Chandel, John M. Denu, Milan Mrksich, Joseph Bass - Science 2013 cited by 661
- Gut microbiome variation modulates the effects of dietary fiber on host metabolism
Authors: Sofía M. Murga-Garrido, Qilin Hong, Tzu-Wen Cross, Evan R. Hutchison, Jessica Han, Sydney P. Thomas, Eugenio I. Vivas, John M. Denu, Danilo G. Ceschin, Zheng-Zheng Tang, Federico E. Rey - Microbiome 2021 cited by 178
- Fasting drives the metabolic, molecular and geroprotective effects of a calorie-restricted diet in mice
Authors: Heidi H. Pak, Spencer A. Haws, Cara L. Green, Mikaela Koller, Mitchell T. Lavarias, Nicole E. Richardson, Shany E. Yang, Sabrina N. Dumas, Michelle M. Sonsalla, Lindsey Bray, Michelle S. Johnson, Stephen Barnes, Victor Darley‐Usmar, Jianhua Zhang, Chi–Liang Eric Yen, John M. Denu, Dudley W. Lamming - Nature Metabolism 2021 cited by 183
- Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction
Authors: Shinichi Someya, Wei Yu, William C. Hallows, Jinze Xu, James M. Vann, Christiaan Leeuwenburgh, Masaru Tanokura, John M. Denu, Tomas A. Prolla - Cell 2010 cited by 1,153
- Mechanisms and Dynamics of Protein Acetylation in Mitochondria
Authors: Josue Baeza, Michael J. Smallegan, John M. Denu - Trends in Biochemical Sciences 2016 cited by 318
- The Human Sir2 Ortholog, SIRT2, Is an NAD+-Dependent Tubulin Deacetylase
Authors: Brian J. North, Brett Marshall, Margie T. Borra, John M. Denu, Eric Verdin - Molecular Cell 2003 cited by 1,524
- Activation of the Protein Deacetylase SIRT6 by Long-chain Fatty Acids and Widespread Deacylation by Mammalian Sirtuins
Authors: Jessica L. Feldman, Josue Baeza, John M. Denu - Journal of Biological Chemistry 2013 cited by 633
- Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases
Authors: William C. Hallows, Susan Lee, John M. Denu - National Academy of Sciences, Proceedings of the National Academy of Sciences 2006 cited by 794
- Calorie Restriction and SIRT3 Trigger Global Reprogramming of the Mitochondrial Protein Acetylome
Authors: Alexander S. Hebert, Kristin E. Dittenhafer‐Reed, Wei Yu, Derek J. Bailey, Ebru S. Selen Alpergin, Melissa Boersma, Joshua J. Carson, Marco Tonelli, Allison J. Balloon, Alan Higbee, Michael S. Westphall, David J. Pagliarini, Tomas A. Prolla, Fariba M. Assadi‐Porter, Sushmita Roy, John M. Denu, Joshua J. Coon - Molecular Cell 2012 cited by 641
- Mechanism of Human SIRT1 Activation by Resveratrol
Authors: Margie T. Borra, Brian C. Smith, John M. Denu - Journal of Biological Chemistry 2005 cited by 1,055
- SIRT3 Protein Deacetylates Isocitrate Dehydrogenase 2 (IDH2) and Regulates Mitochondrial Redox Status
Authors: Wei Yu, Kristin E. Dittenhafer‐Reed, John M. Denu - Journal of Biological Chemistry 2012 cited by 439
- Metabolic Regulation of Histone Post-Translational Modifications
Authors: Jing Fan, Kimberly A. Krautkramer, Jessica L. Feldman, John M. Denu - ACS Chemical Biology 2015 cited by 334
- SIRT3 Deacetylates Mitochondrial 3-Hydroxy-3-Methylglutaryl CoA Synthase 2 and Regulates Ketone Body Production
Authors: Tadahiro Shimazu, Matthew D. Hirschey, Lan Hua, Kristin E. Dittenhafer‐Reed, Bjoern Schwer, David B. Lombard, Li Yu, Jakob Bunkenborg, Frederick W. Alt, John M. Denu, Matthew P. Jacobson, Eric Verdin - Cell Metabolism 2010 cited by 480
- Chemical mechanisms of histone lysine and arginine modifications
Authors: Brian C. Smith, John M. Denu - Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 2008 cited by 387
- Sirtuin Catalysis and Regulation
Authors: Jessica L. Feldman, Kristin E. Dittenhafer‐Reed, John M. Denu - Journal of Biological Chemistry 2012 cited by 244
- Methyl-Metabolite Depletion Elicits Adaptive Responses to Support Heterochromatin Stability and Epigenetic Persistence
Authors: Spencer A. Haws, Deyang Yu, Cunqi Ye, Coral K. Wille, Long C. Nguyen, Kimberly A. Krautkramer, Jay L. Tomasiewicz, Shany E. Yang, Blake R. Miller, Wallace H. Liu, Kazuhiko Igarashi, Rupa Sridharan, Benjamin P. Tu, Vincent L. Cryns, Dudley W. Lamming, John M. Denu - Molecular Cell 2020 cited by 92
- Metabolism and the Epigenome: A Dynamic Relationship
Authors: Spencer A. Haws, Cassandra M. Leech, John M. Denu - Trends in Biochemical Sciences 2020 cited by 101
- Structure and Biochemical Functions of SIRT6
Authors: Patricia W. Pan, Jessica L. Feldman, Mark Devries, Aiping Dong, A.M. Edwards, John M. Denu - Journal of Biological Chemistry 2011 cited by 312
- SIRT3 Mediates Multi-Tissue Coupling for Metabolic Fuel Switching
Authors: Kristin E. Dittenhafer‐Reed, Alicia Richards, Jing Fan, Michael J. Smallegan, Alireza Fotuhi Siahpirani, Zachary A. Kemmerer, Tomas A. Prolla, Sushmita Roy, Joshua J. Coon, John M. Denu - Cell Metabolism 2015 cited by 191
- Sirt3 Promotes the Urea Cycle and Fatty Acid Oxidation during Dietary Restriction
Authors: William C. Hallows, Wei Yu, Brian C. Smith, Mark K. Devires, James J. Ellinger, Shinichi Someya, Michael R. Shortreed, Tomas A. Prolla, John L. Markley, Lloyd M. Smith, Shimin Zhao, Kun‐Liang Guan, John M. Denu - Molecular Cell 2011 cited by 388
