John P. Iredale
Active 1992–2023
- Also published as
- John P Iredale
- 86
- Papers
- 26,060
- Citations
- 82
- h-index
- 86
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine64.5%
- Biochemistry, Genetics and Molecular Biology18%
- Immunology and Microbiology11.7%
- Neuroscience2.1%
- Engineering1.2%
- Pharmacology, Toxicology and Pharmaceutics1%
- Other1.5%
Topics
- Liver physiology and pathology10.3%
- Liver Disease Diagnosis and Treatment8.7%
- Liver Disease and Transplantation2.9%
- Immune cells in cancer2.8%
- Organ Transplantation Techniques and Outcomes1.9%
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis1.7%
- Other71.7%
Coauthors
- Stuart J. Forbes18
- Prakash Ramachandran13
- Neil C. Henderson11
- R. Christopher Benyon10
- Timothy J. Kendall10
- Antonella Pellicoro9
- Jonathan Fallowfield8
- Luke Boulter8
- David C. Hay7
- M J Arthur7
- Michael J.P. Arthur7
- Rebecca L. Aucott7
- Damian J. Mole6
- Derek A. Mann6
- Xiaoying Zhou6
- Alison C. MacKinnon5
- Christopher Benyon5
- Christothea M. Constandinou5
- Harry Millward‐Sadler5
- Davina Wojtacha4
- James A. Ross4
- James R. Black4
- Nathan Trim4
- Nico van Rooijen4
All papers
- Resolving the fibrotic niche of human liver cirrhosis at single-cell level
Authors: Prakash Ramachandran, Ross Dobie, John R. Wilson‐Kanamori, Elena Dorà, Beth E. P. Henderson, N. Thin Luu, Jordan R. Portman, Kylie P. Matchett, Madara Brice, John A. Marwick, Richard S. Taylor, Mirjana Efremova, Roser Vento‐Tormo, Neil O. Carragher, Timothy J. Kendall, Jonathan Fallowfield, Ewen M. Harrison, Damian J. Mole, Stephen J. Wigmore, Philip N. Newsome, Chris J. Weston, John P. Iredale, Frank Tacke, Jeffrey W. Pollard, Chris P. Ponting, John C. Marioni, Sarah A. Teichmann, Neil C. Henderson - Nature 2019 cited by 1,801
- Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis
Authors: Prakash Ramachandran, Antonella Pellicoro, Madeleine A. Vernon, Luke Boulter, Rebecca L. Aucott, Aysha Ali, Stephen N. Hartland, Victoria Snowdon, A. Cappon, Timothy T. Gordon‐Walker, Mike J. Williams, Donald R. Dunbar, Jonathan Manning, Nico van Rooijen, Jonathan Fallowfield, Stuart J. Forbes, John P. Iredale - National Academy of Sciences, Proceedings of the National Academy of Sciences 2012 cited by 985
- Liver fibrosis and repair: immune regulation of wound healing in a solid organ
Authors: Antonella Pellicoro, Prakash Ramachandran, John P. Iredale, Jonathan Fallowfield - Nature reviews. Immunology 2014 cited by 1,294
- Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs
Authors: Neil C. Henderson, Thomas D. Arnold, Yoshio Katamura, Marilyn M. Giacomini, Juan Duque Rodríguez, Joseph H. McCarty, Antonella Pellicoro, Elisabeth Raschperger, Christer Betsholtz, Peter Ruminski, David W. Griggs, Michael J. Prinsen, Jacquelyn J. Maher, John P. Iredale, Adam Lacy‐Hulbert, Ralf H. Adams, Dean Sheppard - Nature Medicine 2013 cited by 874
- Matrix stiffness modulates proliferation, chemotherapeutic response, and dormancy in hepatocellular carcinoma cells
Authors: Jörg Schrader, Timothy T. Gordon‐Walker, Rebecca L. Aucott, M. van Deemter, Alexander Quaas, Shaun Walsh, Daniel Benten, Stuart J. Forbes, Rebecca G. Wells, John P. Iredale - Hepatology 2010 cited by 735
- TGFβ inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence
Authors: Thomas G. Bird, Miryam Müller, Luke Boulter, David F. Vincent, Rachel A. Ridgway, Elena Lopez-Guadamillas, Wei‐Yu Lu, Thomas Jamieson, Olivier Govaere, Andrew D. Campbell, Sofía Ferreira-González, Alicia M. Cole, Trevor Hay, Kenneth J. Simpson, William Clark, Ann Hedley, Mairi Clarke, Pauline Gentaz, Colin Nixon, S Bryce, Christos Kiourtis, Joep Sprangers, Robert J. B. Nibbs, Nico van Rooijen, Laurent Bartholin, Steven R. McGreal, Udayan Apte, Simon T. Barry, John P. Iredale, Alan R. Clarke, Manuel Serrano, Tania Roskams, Owen J. Sansom, Stuart J. Forbes - Science Translational Medicine 2018 cited by 264
- Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair
Authors: Jeremy S. Duffield, Stuart J. Forbes, Christothea M. Constandinou, Spike Clay, Marina Partolina, Srilatha Vuthoori, Shengji Wu, Richard A. Lang, John P. Iredale - Journal of Clinical Investigation 2005 cited by 1,427
- Models of liver fibrosis: exploring the dynamic nature of inflammation and repair in a solid organ
Authors: John P. Iredale - Journal of Clinical Investigation 2007 cited by 859
- Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease
Authors: Luke Boulter, Olivier Govaere, Tom G Bird, Sorina Radulescu, Prakash Ramachandran, Antonella Pellicoro, Rachel A. Ridgway, Sang Soo Seo, Bart Spee, Nico van Rooijen, Owen J. Sansom, John P. Iredale, Sally Lowell, Tania Roskams, Stuart J. Forbes - Nature Medicine 2012 cited by 730
- Ly6Chi Monocytes Direct Alternatively Activated Profibrotic Macrophage Regulation of Lung Fibrosis
Authors: Michael Gibbons, Alison C. MacKinnon, Prakash Ramachandran, Kevin Dhaliwal, Rodger Duffin, Alexander Phythian‐Adams, Nico van Rooijen, Christopher Haslett, Sarah Howie, A. John Simpson, Nikhil Hirani, Jack Gauldie, John P. Iredale, Tariq Sethi, Stuart J. Forbes - American Journal of Respiratory and Critical Care Medicine 2011 cited by 473
- Galectin-3 regulates myofibroblast activation and hepatic fibrosis
Authors: Neil C. Henderson, Alison C. MacKinnon, Sarah L. Farnworth, Françoise Poirier, Francesco Paolo Russo, John P. Iredale, Christopher Haslett, Kenneth J. Simpson, Tariq Sethi - National Academy of Sciences, Proceedings of the National Academy of Sciences 2006 cited by 622
- Galectin-3 Expression and Secretion Links Macrophages to the Promotion of Renal Fibrosis
Authors: Neil C. Henderson, Alison C. MacKinnon, Sarah L. Farnworth, Tiina Kipari, Christopher Haslett, John P. Iredale, Fu‐Tong Liu, Jeremy Hughes, Tariq Sethi - American Journal Of Pathology 2008 cited by 559
- Regression of Liver Fibrosis
Authors: John P. Iredale, Lara Campana - Seminars in Liver Disease 2017 cited by 391
- Macrophage therapy for murine liver fibrosis recruits host effector cells improving fibrosis, regeneration, and function
Authors: James A. Thomas, Caroline Pope, Davina Wojtacha, Andrew J. Robson, Timothy T. Gordon‐Walker, Stephen N. Hartland, Prakash Ramachandran, M. van Deemter, David Hume, John P. Iredale, Stuart J. Forbes - Hepatology 2011 cited by 340
- Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors.
Authors: John P. Iredale, R. Christopher Benyon, J. Pickering, M. McCullen, Michael Northrop, Susannah Pawley, Christopher Hovell, M J Arthur - Journal of Clinical Investigation 1998 cited by 1,066
- Hepatic progenitor cells of biliary origin with liver repopulation capacity
Authors: Wei‐Yu Lu, Thomas G. Bird, Luke Boulter, Atsunori Tsuchiya, Alicia M. Cole, Trevor Hay, Rachel V. Guest, Davina Wojtacha, Tak Yung Man, Alison C. MacKinnon, Rachel A. Ridgway, Timothy J. Kendall, Michael J. Williams, Thomas Jamieson, Alexander Raven, David C. Hay, John P. Iredale, Alan R. Clarke, Owen J. Sansom, Stuart J. Forbes - Nature Cell Biology 2015 cited by 500
- Scar-Associated Macrophages Are a Major Source of Hepatic Matrix Metalloproteinase-13 and Facilitate the Resolution of Murine Hepatic Fibrosis
Authors: Jonathan Fallowfield, Masashi Mizuno, Timothy J. Kendall, Christothea M. Constandinou, R. Christopher Benyon, Jeremy S. Duffield, John P. Iredale - The Journal of Immunology 2007 cited by 471
- MDR1 deficiency impairs mitochondrial homeostasis and promotes intestinal inflammation
Authors: Gwo‐Tzer Ho, Rhona Aird, B Liu, Ray Boyapati, Nicholas A. Kennedy, David A. Dorward, Colin Noble, Takahiko Shimizu, Roderick N. Carter, Etienne Chew, Nicholas M. Morton, Adriano G. Rossi, R. Balfour Sartor, John P. Iredale, Jack Satsangi - Mucosal Immunology 2017 cited by 111
- Prostaglandin E 2 promotes intestinal inflammation via inhibiting microbiota-dependent regulatory T cells
Authors: Siobhan Crittenden, Marie Goepp, Jolinda Pollock, Calum T. Robb, Danielle J. Smyth, You Zhou, Robert Andrews, Victoria J. Tyrrell, Konstantinos Gkikas, Alexander Adima, Richard A. O’Connor, Luke C. Davies, Xuefeng Li, Hatti X. Yao, Gwo‐Tzer Ho, Xiaozhong Zheng, Amil Mair, Sonja Vermeren, Bin‐Zhi Qian, Damian J. Mole, Konstantinos Gerasimidis, Jürgen Schwarze, Richard Breyer, Mark J. Arends, Valerie B. O’Donnell, John P. Iredale, Stephen M. Anderton, Shuh Narumiya, Rick M. Maizels, Adriano G. Rossi, Sarah Howie, Chengcan Yao - Science Advances 2021 cited by 101
- Bone marrow injection stimulates hepatic ductular reactions in the absence of injury via macrophage-mediated TWEAK signaling
Authors: Thomas G. Bird, Wei‐Yu Lu, Luke Boulter, Sabrina Gordon-Keylock, Rachel A. Ridgway, Michael J. Williams, Jessica Taube, James A. Thomas, Davina Wojtacha, Adriana Rosa Gambardella, Owen J. Sansom, John P. Iredale, Stuart J. Forbes - National Academy of Sciences, Proceedings of the National Academy of Sciences 2013 cited by 167
- Extracellular matrix degradation in liver fibrosis: Biochemistry and regulation
Authors: John P. Iredale, Alexandra Thompson, Neil C. Henderson - Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2012 cited by 267
- Scraping fibrosis: Expressway to the core of fibrosis
Authors: Wajahat Z. Mehal, John P. Iredale, Scott L. Friedman - Nature Medicine 2011 cited by 212
- Hepatic changes in the failing Fontan circulation
Authors: C. Kiesewetter, Nick Sheron, Joseph Vettukattill, Nigel Hacking, Brian Stedman, Harry Millward‐Sadler, Marcus P. Haw, Richard Cope, Anthony P. Salmon, Muthukumaran C. Sivaprakasam, Timothy J. Kendall, Barry R. Keeton, John P. Iredale, Gruschen Veldtman - Heart 2006 cited by 365
- Now there are many (stages) where before there was one
Authors: Guadalupe García–Tsao, Scott L. Friedman, John P. Iredale, Massimo Pinzani - Hepatology 2009 cited by 538
