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John R. Griffiths

Active 1971–2021

113
Papers
24,802
Citations
84
h-index
109
i10-index

Citations

Citations per year for John R. Griffiths1966: 1 citations1973: 1 citations1974: 2 citations1976: 1 citations1978: 4 citations1979: 2 citations1980: 1 citations1981: 4 citations1982: 11 citations1983: 6 citations1984: 7 citations1985: 6 citations1986: 11 citations1987: 8 citations1988: 7 citations1989: 5 citations1990: 5 citations1991: 6 citations1992: 9 citations1993: 11 citations1994: 13 citations1995: 11 citations1996: 20 citations1997: 20 citations1998: 30 citations1999: 60 citations2000: 71 citations2001: 65 citations2002: 100 citations2003: 139 citations2004: 203 citations2005: 167 citations2006: 197 citations2007: 177 citations2008: 193 citations2009: 222 citations2010: 309 citations2011: 338 citations2012: 320 citations2013: 308 citations2014: 268 citations2015: 256 citations2016: 259 citations2017: 265 citations2018: 278 citations2019: 699 citations2020: 658 citations2021: 681 citations2022: 521 citations2023: 339 citations2024: 477 citations2025: 205 citations2026: 9 citations1967–1972: no citations, so these years are not shown1975: no citations, so this year is not shown1977: no citations, so this year is not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 2,943 citing papers, 27.1% of this breakdownUnited Kingdom: 1,258 citing papers, 11.6% of this breakdownChina: 1,071 citing papers, 9.9% of this breakdownGermany: 608 citing papers, 5.6% of this breakdownItaly: 459 citing papers, 4.2% of this breakdownCanada: 344 citing papers, 3.2% of this breakdownNetherlands: 343 citing papers, 3.2% of this breakdownFrance: 335 citing papers, 3.1% of this breakdownSpain: 304 citing papers, 2.8% of this breakdownAustralia: 293 citing papers, 2.7% of this breakdownJapan: 234 citing papers, 2.1% of this breakdownSwitzerland: 196 citing papers, 1.8% of this breakdown
0%27.1%Other 22.7%

Institutions

Fields

  • Medicine48.2%
  • Biochemistry, Genetics and Molecular Biology35.4%
  • Materials Science3.5%
  • Immunology and Microbiology3%
  • Engineering2.8%
  • Chemistry2.2%
  • Other4.9%

Topics

  • Cancer, Hypoxia, and Metabolism5.9%
  • Pancreatic and Hepatic Oncology Research3.5%
  • Advanced MRI Techniques and Applications2.8%
  • Cancer Cells and Metastasis2.4%
  • Nanoplatforms for cancer theranostics2.1%
  • Epigenetics and DNA Methylation1.8%
  • Other81.5%

Coauthors

All papers

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  1. Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer

    Authors: Kenneth P. Olive, Michael A. Jacobetz, Christian J. Davidson, Aarthi Gopinathan, Dominick J. O. McIntyre, Davina J. Honess, Basetti Madhu, Mae A. Goldgraben, Meredith E. Caldwell, David Allard, Kristopher K. Frese, Gina M. DeNicola, Christine Feig, Chelsea Combs, Stephen P. Winter, Heather Ireland‐Zecchini, Stefanie Reichelt, William Howat, Alex Chang, Mousumi Dhara, Lifu Wang, Felix Rückert, Robert Grützmann, Christian Pilarsky, Kamel Izeradjene, Sunil R. Hingorani, Pearl S. Huang, Susan Davies, William Plunkett, Merrill J. Egorin, Ralph H. Hruban, Nigel Whitebread, Karen McGovern, Julian Adams, Christine A. Iacobuzio–Donahue, John R. Griffiths, David A. Tuveson - Science 2009 cited by 3,164

  2. SREBP Activity Is Regulated by mTORC1 and Contributes to Akt-Dependent Cell Growth

    Authors: Thomas Porstmann, Cláudio R. Santos, B Griffiths, Megan Cully, Mary Wu, Sally J. Leevers, John R. Griffiths, Yuen‐Li Chung, Almut Schulze - Cell Metabolism 2008 cited by 1,379

  3. Imaging biomarker roadmap for cancer studies

    Authors: James P.B. O’Connor, Eric O. Aboagye, Judith E. Adams, Hugo J.W.L. Aerts, Sally F. Barrington, Ambros J. Beer, Ronald Boellaard, Sarah E. Bohndiek, Michael Brady, Gina Brown, David L. Buckley, Thomas L. Chenevert, Laurence P. Clarke, Sandra Collette, Gary Cook, Nandita M. deSouza, John Dickson, Caroline Dive, Jeffrey L. Evelhoch, Corinne Faivre‐Finn, Ferdia A. Gallagher, Fiona J. Gilbert, Robert J. Gillies, Vicky Goh, John R. Griffiths, Ashley M. Groves, Steve Halligan, Adrian L. Harris, David J. Hawkes, Otto S. Hoekstra, Erich P. Huang, Brian Hutton, Edward F. Jackson, Gordon C. Jayson, Andrew Jones, Dow‐Mu Koh, Denis Lacombe, Philippe Lambin, Nathalie Lassau, Martin O. Leach, Ting-Yim Lee, Edward Leen, Jason S. Lewis, Yan Liu, Mark F. Lythgoe, Prakash Manoharan, Ross J. Maxwell, Kenneth A. Miles, Bruno Morgan, Steve Morris, Tony Ng, Anwar R. Padhani, Geoff J.M. Parker, Mike Partridge, Arvind P. Pathak, Andrew C. Peet, Shonit Punwani, Andrew R. Reynolds, Simon P. Robinson, Lalitha Shankar, Ricky A. Sharma, Dmitry Soloviev, Sigrid Stroobants, Daniel C. Sullivan, Stuart A. Taylor, Paul S. Tofts, Gillian M. Tozer, Marcel van Herk, Simon Walker‐Samuel, James Wason, Kaye J. Williams, Paul Workman, Thomas E. Yankeelov, Kevin M. Brindle, Lisa M. McShane, Alan Jackson, John C. Waterton - Nature Reviews Clinical Oncology 2016 cited by 1,078

  4. S-2-hydroxyglutarate regulates CD8+ T-lymphocyte fate

    Authors: Petros A. Tyrakis, Asís Palazón, David Macías, Kian Leong Lee, Anthony T. Phan, Pedro Veliça, Jia You, Grace Sushin Chia, Jingwei Sim, Andrew L. Doedens, Alice Abélanet, Colin E. Evans, John R. Griffiths, Lorenz Poellinger, Ananda W. Goldrath, Randall S. Johnson - Nature 2016 cited by 423

  5. HIF-1-Independent Mechanisms Regulating Metabolic Adaptation in Hypoxic Cancer Cells

    Authors: Shen‐Han Lee, Monika Golinska, John R. Griffiths - Cells 2021 cited by 158

  6. How and Why Are Cancers Acidic? Carbonic Anhydrase IX and the Homeostatic Control of Tumour Extracellular pH

    Authors: Shen‐Han Lee, John R. Griffiths - Cancers 2020 cited by 145

  7. PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP

    Authors: Thomas Porstmann, B Griffiths, Yuen‐Li Chung, Oona Delpuech, John R. Griffiths, Julian Downward, Almut Schulze - Oncogene 2005 cited by 448

  8. The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis

    Authors: Charles Massie, Andy G. Lynch, Antonio Ramos‐Montoya, Joan Boren, Rory Stark, Ladan Fazli, Anne Y. Warren, Helen E. Scott, Basetti Madhu, Naomi L. Sharma, Hélène Bon, Vinny Zecchini, Donna-Michelle Smith, Gina M. DeNicola, Nik Mathews, Michelle Osborne, James Hadfield, Stewart MacArthur, Boris Adryan, Scott K. Lyons, Kevin M. Brindle, John R. Griffiths, Martin Gleave, Paul S. Rennie, David E. Neal, Ian G. Mills - The EMBO Journal 2011 cited by 632

  9. Accumulation of Krebs cycle intermediates and over-expression of HIF1α in tumours which result from germline FH and SDH mutations

    Authors: Patrick J. Pollard, J.-J. Brière, Neyaz Alam, Julian Barwell, Ella Barclay, Noel C. Wortham, Toby Hunt, Murray D. Mitchell, S. E. Olpin, Stuart J. Moat, Iain P. Hargreaves, Simon Heales, Yuen‐Li Chung, John R. Griffiths, A. Dalgleish, John A. McGrath, Michael J. Gleeson, S V Hodgson, Richard Poulsom, Pierre Rustin, Ian Tomlinson - Human Molecular Genetics 2005 cited by 849

  10. The North‐West Diabetes Foot Care Study: incidence of, and risk factors for, new diabetic foot ulceration in a community‐based patient cohort

    Authors: Caroline A. Abbott, Anne L. Carrington, H. Ashe, Sarah C. Bath, L. C. Every, John R. Griffiths, A. W. Hann, Ahmed Hussein, Nicky Jackson, Kristen E. Johnson, C. H. Ryder, R. Torkington, E. R. E. Van Ross, A Whalley, Peris Widdows, Sheila Williamson, Andrew J.M. Boulton - Diabetic Medicine 2002 cited by 1,059

  11. Causes and consequences of tumour acidity and implications for treatment

    Authors: Marion Stubbs, Paul M.J. McSheehy, John R. Griffiths, C.L. Bashford - Molecular Medicine Today 2000 cited by 770

  12. Phase IIa randomized, placebo-controlled study of antimicrobial photodynamic therapy in bacterially colonized, chronic leg ulcers and diabetic foot ulcers: a new approach to antimicrobial therapy

    Authors: S. Morley, John R. Griffiths, G. Philips, Harry Moseley, Catherine O’Grady, Kirste Mellish, C.L. Lankester, Barzo Faris, Robert J. Young, Sarah Brown, Lesley E. Rhodes - British Journal of Dermatology 2012 cited by 141

  13. Combined Metabolomic and Proteomic Analysis of Human Atrial Fibrillation

    Authors: Manuel Mayr, Shamil Yusuf, Graeme Weir, Yuen-Li Chung, Ursula Mayr, Xiaoke Yin, Christophe Ladroue, Basetti Madhu, Neil Roberts, Ayesha De Souza, Salim Fredericks, Marion Stubbs, John R. Griffiths, Marjan Jahangiri, Qingbo Xu, A. John Camm - Journal of the American College of Cardiology 2008 cited by 249

  14. Are cancer cells acidic?

    Authors: John R. Griffiths - British Journal of Cancer 1991 cited by 589

  15. Fumarate Hydratase Loss Causes Combined Respiratory Chain Defects

    Authors: Petros A. Tyrakis, Marie E. Yurkovich, Marco Sciacovelli, Evangelia K. Papachristou, Hannah R. Bridges, Edoardo Gaude, A. Schreiner, Clive S. D’Santos, Judy Hirst, Juan R. Hernández‐Fernaud, Roger Springett, John R. Griffiths, Christian Frezza - Cell Reports 2017 cited by 97

  16. The action of β-hydroxybutyrate on the growth, metabolism and global histone H3 acetylation of spontaneous mouse mammary tumours: evidence of a β-hydroxybutyrate paradox

    Authors: Loreta M. Rodrigues, Santiago Uribe‐Lewis, Basetti Madhu, Davina J. Honess, Marion Stubbs, John R. Griffiths - Cancer & Metabolism 2017 cited by 80

  17. Metabolic profiles of human brain tumors using quantitative in vivo 1H magnetic resonance spectroscopy

    Authors: Franklyn A. Howe, Sarah J. Barton, Simon Cudlip, Marion Stubbs, D. Saunders, Mary M. Murphy, P. Wilkins, Kirstie S. Opstad, Victoria L. Doyle, Mary A. McLean, B. Anthony Bell, John R. Griffiths - Magnetic Resonance in Medicine 2003 cited by 537

  18. Beyond factor H: The impact of genetic-risk variants for age-related macular degeneration on circulating factor-H-like 1 and factor-H-related protein concentrations

    Authors: Valentina Cipriani, Anna Tierney, John R. Griffiths, Verena Zuber, Panagiotis I. Sergouniotis, John R.W. Yates, Anthony T. Moore, Paul N. Bishop, Simon J. Clark, Richard D. Unwin - The American Journal of Human Genetics 2021 cited by 52

  19. Simultaneous analysis of relative protein expression levels across multiple samples using iTRAQ isobaric tags with 2D nano LC–MS/MS

    Authors: Richard D. Unwin, John R. Griffiths, Anthony D. Whetton - Nature Protocols 2010 cited by 253

  20. Proteomics, Metabolomics, and Immunomics on Microparticles Derived From Human Atherosclerotic Plaques

    Authors: Manuel Mayr, David J. Grainger, Ursula Mayr, Aurélie S. Leroyer, Guy Lesèche, Anissa Sidibé, Olivier Herbin, Xiaoke Yin, Aldrin V. Gomes, Bassetti Madhu, John R. Griffiths, Qingbo Xu, Alain Tedgui, Chantal M. Boulanger - Circulation Cardiovascular Genetics 2009 cited by 135

  21. Carbonic anhydrase IX is a pH-stat that sets an acidic tumour extracellular pH in vivo

    Authors: Shen‐Han Lee, Dominick J. O. McIntyre, Davina J. Honess, Alžbeta Hulı́ková, Jesús Pacheco‐Torres, Sebastián Cerdán, Pawel Swietach, Adrian L. Harris, John R. Griffiths - British Journal of Cancer 2018 cited by 126

  22. Magnetic Resonance Neurography

    Authors: Franklyn A. Howe, Aaron G. Filler, B. A. Bell, John R. Griffiths - Magnetic Resonance in Medicine 1992 cited by 199

  23. A PP1–PP2A phosphatase relay controls mitotic progression

    Authors: Ágnes Grallert, Elvan Böke, Anja Hagting, Ben Hodgson, Yvonne Connolly, John R. Griffiths, Duncan L. Smith, Jonathon Pines, Iain Hagan - Nature 2014 cited by 195

  24. Dynamic asymmetry of phosphocreatine concentration and O2 uptake between the on‐ and off‐transients of moderate‐ and high‐intensity exercise in humans

    Authors: Harry B. Rossiter, S. A. Ward, John M. Kowalchuk, Franklyn A. Howe, John R. Griffiths, Brian J. Whipp - The Journal of Physiology 2002 cited by 358