John W. Kappler
Active 1970–2024
- 183
- Papers
- 44,125
- Citations
- 120
- h-index
- 182
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Immunology and Microbiology48.6%
- Medicine30.8%
- Biochemistry, Genetics and Molecular Biology17%
- Neuroscience1.4%
- Agricultural and Biological Sciences0.6%
- Environmental Science0.3%
- Other1.3%
Topics
- T-cell and B-cell Immunology15.1%
- Immune Cell Function and Interaction14.7%
- Immunotherapy and Immune Responses9%
- Monoclonal and Polyclonal Antibodies Research3.7%
- Immune Response and Inflammation2.7%
- CAR-T cell therapy research2.4%
- Other52.4%
Coauthors
- Philippa Marrack163
- Frances Crawford22
- Janice White19
- David A. Hildeman13
- Shaodong Dai12
- Gongyi Zhang11
- Ralph T. Kubo10
- Kathryn Haskins9
- Kira Rubtsova9
- Megan K. L. MacLeod9
- Ross M. Kedl9
- T. Kent Teague8
- Tom Mitchell8
- Anatoly V. Rubtsov7
- Brian C. Schaefer7
- Haolin Liu7
- John C. Cambier7
- Laurent Gapin7
- Pengcheng Wei7
- Thomas C. Mitchell7
- Zhongzhou Chen7
- Amy S. McKee6
- Ann M. Pullen6
- Anthony T. Vella6
All papers
- Toll-like receptor 7 (TLR7)–driven accumulation of a novel CD11c+ B-cell population is important for the development of autoimmunity
Authors: Anatoly V. Rubtsov, Kira Rubtsova, Aryeh Fischer, Richard T. Meehan, Joann Zell Gillis, John W. Kappler, Philippa Marrack - Blood 2011 cited by 807
- An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder
Authors: Michael B. Jordan, David A. Hildeman, John W. Kappler, Philippa Marrack - Blood 2004 cited by 713
- B cells expressing the transcription factor T-bet drive lupus-like autoimmunity
Authors: Kira Rubtsova, Anatoly V. Rubtsov, Joshua M. Thurman, Johanna M. Mennona, John W. Kappler, Philippa Marrack - Journal of Clinical Investigation 2017 cited by 279
- CD11c-Expressing B Cells Are Located at the T Cell/B Cell Border in Spleen and Are Potent APCs
Authors: Anatoly V. Rubtsov, Kira Rubtsova, John W. Kappler, Jordan Jacobelli, Rachel S. Friedman, Philippa Marrack - The Journal of Immunology 2015 cited by 237
- T-box transcription factor T-bet, a key player in a unique type of B-cell activation essential for effective viral clearance
Authors: Kira Rubtsova, Anatoly V. Rubtsov, Linda F. van Dyk, John W. Kappler, Philippa Marrack - National Academy of Sciences, Proceedings of the National Academy of Sciences 2013 cited by 310
- Autoimmune disease: why and where it occurs
Authors: Philippa Marrack, John W. Kappler, Brian L. Kotzin - Nature Medicine 2001 cited by 605
- Observation of Antigen-Dependent CD8+ T-Cell/ Dendritic Cell Interactions in Vivo
Authors: Brian C. Schaefer, Michele L. Schaefer, John W. Kappler, Philippa Marrack, Ross M. Kedl - Cellular Immunology 2001 cited by 401
- How the T Cell Repertoire Becomes Peptide and MHC Specific
Authors: Eric S. Huseby, Janice White, Frances Crawford, Tibor Vass, Dean Becker, Clemencia Pinilla, Philippa Marrack, John W. Kappler - Cell 2005 cited by 323
- Lysosomal cathepsin creates chimeric epitopes for diabetogenic CD4 T cells via transpeptidation
Authors: Brendan Reed, Frances Crawford, Ryan C. Hill, Niyun Jin, Janice White, S. Harsha Krovi, Philippa Marrack, Kirk C. Hansen, John W. Kappler - The Journal of Experimental Medicine 2020 cited by 58
- T Cell Allorecognition via Molecular Mimicry
Authors: W.A. Macdonald, Zhenjun Chen, Stéphanie Gras, Julia K. Archbold, F.E. Tynan, Craig S. Clements, Mandvi Bharadwaj, Lars Kjer‐Nielsen, Philippa M. Saunders, Matthew C. J. Wilce, F. T. Crawford, B. Stadinsky, David C. Jackson, Andrëw G. Brööks, Anthony W. Purcell, John W. Kappler, Scott R. Burrows, Jamie Rossjohn, James McCluskey - Immunity 2009 cited by 260
- Islet-Derived CD4 T Cells Targeting Proinsulin in Human Autoimmune Diabetes
Authors: Aaron W. Michels, Laurie G. Landry, Kristen A. McDaniel, Liping Yu, Martha Campbell‐Thompson, William W. Kwok, Kenneth L. Jones, Peter A. Gottlieb, John W. Kappler, Qizhi Tang, Bart O. Roep, Mark A. Atkinson, Clayton E. Mathews, Maki Nakayama - Diabetes 2016 cited by 196
- The basis of a more contagious 501Y.V1 variant of SARS-CoV-2
Authors: Haolin Liu, Qianqian Zhang, Pengcheng Wei, Zhongzhou Chen, Katja Aviszus, John Yang, Walter Downing, Chengyu Jiang, Bo Liang, Lyndon Reynoso, Gregory P. Downey, Stephen K. Frankel, John W. Kappler, Philippa Marrack, Gongyi Zhang - Cell Research 2021 cited by 165
- T cell tolerance by clonal elimination in the thymus
Authors: John W. Kappler, Neal W. Roehm, Philippa Marrack - Cell 1987 cited by 2,215
- Type I Interferons Keep Activated T Cells Alive
Authors: Philippa Marrack, John W. Kappler, Tom Mitchell - The Journal of Experimental Medicine 1999 cited by 766
- Specificity and detection of insulin-reactive CD4 + T cells in type 1 diabetes in the nonobese diabetic (NOD) mouse
Authors: Frances Crawford, Brian D. Stadinski, Niyun Jin, Aaron W. Michels, Maki Nakayama, Philip F. Pratt, Philippa Marrack, George S. Eisenbarth, John W. Kappler - National Academy of Sciences, Proceedings of the National Academy of Sciences 2011 cited by 140
- Reactive Oxygen Species Regulate Activation-Induced T Cell Apoptosis
Authors: David A. Hildeman, Tom Mitchell, T. Kent Teague, Peter M. Henson, Brian J. Day, John W. Kappler, Philippa Marrack - Immunity 1999 cited by 484
- TLR7 drives accumulation of ABCs and autoantibody production in autoimmune-prone mice
Authors: Anatoly V. Rubtsov, Kira Rubtsova, John W. Kappler, Philippa Marrack - Immunologic Research 2012 cited by 96
- Control of Homeostasis of CD8 + Memory T Cells by Opposing Cytokines
Authors: Chia‐Chi Ku, Masaaki Murakami, Akemi Sakamoto, John W. Kappler, Philippa Marrack - Science 2000 cited by 820
- Chromogranin A is an autoantigen in type 1 diabetes
Authors: Brian D. Stadinski, Thomas Delong, Nichole Reisdorph, Richard Reisdorph, Roger Powell, Michael Armstrong, Jon D. Piganelli, Gene Barbour, Brenda Bradley, Frances Crawford, Philippa Marrack, Sushil K. Mahata, John W. Kappler, Kathryn Haskins - Nature Immunology 2010 cited by 333
- Genetic and hormonal factors in female-biased autoimmunity
Authors: Anatoly V. Rubtsov, Kira Rubtsova, John W. Kappler, Philippa Marrack - Autoimmunity Reviews 2010 cited by 201
- Diabetogenic T cells recognize insulin bound to IA g7 in an unexpected, weakly binding register
Authors: Brian D. Stadinski, Li Zhang, Frances Crawford, Philippa Marrack, George S. Eisenbarth, John W. Kappler - National Academy of Sciences, Proceedings of the National Academy of Sciences 2010 cited by 191
- Memory CD4 T cells: generation, reactivation and re‐assignment
Authors: Megan K. L. MacLeod, John W. Kappler, Philippa Marrack - Immunology 2010 cited by 165
- Host DNA released in response to aluminum adjuvant enhances MHC class II-mediated antigen presentation and prolongs CD4 T-cell interactions with dendritic cells
Authors: Amy S. McKee, Matthew A. Burchill, Michael W. Munks, Lei Jin, John W. Kappler, Rachel S. Friedman, Jordan Jacobelli, Philippa Marrack - National Academy of Sciences, Proceedings of the National Academy of Sciences 2013 cited by 137
- Generation of functional human thymic cells from induced pluripotent stem cells
Authors: Stephan A. Ramos, J. Jason Morton, Prabha Yadav, Brendan Reed, Sheila I Alizadeh, Ali H. Shilleh, Loni Perrenoud, James Jaggers, John W. Kappler, Antonio Jimeno, Holger A. Russ - Journal of Allergy and Clinical Immunology 2021 cited by 33
