Joost Schymkowitz
Active 1994–2025
- 138
- Papers
- 21,369
- Citations
- 67
- h-index
- 123
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology51.4%
- Medicine33.5%
- Agricultural and Biological Sciences3.1%
- Neuroscience2.9%
- Materials Science2.1%
- Immunology and Microbiology2%
- Other5%
Topics
- Alzheimer's disease research and treatments7.2%
- Protein Structure and Dynamics6.4%
- RNA Research and Splicing5.4%
- RNA and protein synthesis mechanisms3.5%
- Computational Drug Discovery Methods2.8%
- RNA modifications and cancer2.7%
- Other72%
Coauthors
- Frédéric Rousseau129
- Nikolaos Louros27
- Luís Serrano19
- Rodrigo Gallardo18
- Emiel Michiels13
- Joke Reumers13
- Rob van der Kant13
- Bert Houben12
- Francois Stricher11
- Sebastian Maurer‐Stroh11
- Matthias De Vleeschouwer10
- Meine Ramakers10
- Jan A. Delcour9
- Katerina Konstantoulea9
- Greet De Baets8
- Ladan Khodaparast8
- Laleh Khodaparast8
- Ludo Van Den Bosch8
- Gabriele Orlando7
- Margarita Monge‐Morera7
- Philip Van Damme7
- Ramon Duran‐Romaña7
- Bart De Strooper6
- Christine Van Broeckhoven6
All papers
- Protein Phase Separation: A New Phase in Cell Biology
Authors: Steven Boeynaems, Simon Alberti, Nicolas L. Fawzi, Tanja Mittag, Magdalini Polymenidou, Frédéric Rousseau, Joost Schymkowitz, James Shorter, Benjamin Wolozin, Ludo Van Den Bosch, Péter Tompa, Mónika Fuxreiter - Trends in Cell Biology 2018 cited by 2,126
- The FoldX web server: an online force field
Authors: Joost Schymkowitz, Jean‐Paul Borg, François Stricher, Rebekah de Nys, Françoise Rousseau-Hans, L. Serrano - Nucleic Acids Research, Nucleic Acids Res. 2005 cited by 2,881
- Prediction of sequence-dependent and mutational effects on the aggregation of peptides and proteins
Authors: Ana María Fernández‐Escamilla, Frédéric Rousseau, Joost Schymkowitz, Luís Serrano - Nature Biotechnology 2004 cited by 1,713
- Mechanisms and pathology of protein misfolding and aggregation
Authors: Nikolaos Louros, Joost Schymkowitz, Frédéric Rousseau - Nature Reviews Molecular Cell Biology 2023 cited by 236
- A guide to studying protein aggregation
Authors: Joëlle A.J. Housmans, Guiqin Wu, Joost Schymkowitz, Frédéric Rousseau - FEBS Journal 2021 cited by 199
- Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics
Authors: Steven Boeynaems, Elke Bogaert, Dénes Kovács, Albert Konijnenberg, Evy Timmerman, Alexander N. Volkov, Mainak Guharoy, Mathias De Decker, Tom Jaspers, Veronica H. Ryan, Abigail M. Janke, Pieter Baatsen, Thomas Vercruysse, Regina‐Maria Kolaitis, Dirk Daelemans, J. Paul Taylor, Nancy Kedersha, Paul Anderson, Francis Impens, Frank Sobott, Joost Schymkowitz, Frédéric Rousseau, Nicolas L. Fawzi, Wim Robberecht, Philip Van Damme, Péter Tompa, Ludo Van Den Bosch - Molecular Cell 2017 cited by 545
- Exploring the sequence determinants of amyloid structure using position-specific scoring matrices
Authors: Sebastian Maurer‐Stroh, Maja Debulpaep, Nico Kuemmerer, Manuela López de la Paz, Ivo C. Martins, Joke Reumers, Kyle L. Morris, Alastair Copland, Louise C. Serpell, Luís Serrano, Joost Schymkowitz, Frédéric Rousseau - Nature Methods 2010 cited by 689
- Rational Design of Amyloid‐Like Fibrillary Structures for Tailoring Food Protein Techno‐Functionality and Their Potential Health Implications
Authors: Koen J.A. Jansens, Ine Rombouts, Charlotte Grootaert, Kristof Brijs, John Van Camp, Paul Van der Meeren, Frédéric Rousseau, Joost Schymkowitz, Jan A. Delcour - Comprehensive Reviews in Food Science and Food Safety 2018 cited by 176
- TDP-43 pathology is associated with increased tau burdens and seeding
Authors: Sandra O. Tomé, Grigoria Tsaka, Alicja Ronisz, Simona Ospitalieri, Klara Gawor, Luis Aragão Gomes, Markus Otto, Christine A. F. Von Arnim, Philip Van Damme, Ludo Van Den Bosch, Estifanos Ghebremedhin, Celeste Laureyssen, Kristel Sleegers, Rik Vandenberghe, Frédéric Rousseau, Joost Schymkowitz, Dietmar Rudolf Thal - Molecular Neurodegeneration 2023 cited by 63
- Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio
Authors: Inna Kuperstein, Kerensa Broersen, Iryna Benilova, Jef Rozenski, Wim Jonckheere, Maja Debulpaep, Annelies Vandersteen, Ine Segers‐Nolten, Kees van der Werf, Vinod Subramaniam, Dries Braeken, Geert Callewaert, Carmen Bartic, Rudi D’Hooge, Ivo C. Martins, Frédéric Rousseau, Joost Schymkowitz, Bart De Strooper - The EMBO Journal 2010 cited by 538
- WALTZ-DB 2.0: an updated database containing structural information of experimentally determined amyloid-forming peptides
Authors: Nikolaos N. Louros, Katerina Konstantoulea, Matthias De vleeschouwer, Meine Ramakers, Joost Schymkowitz, Frederic Rousseau - Nucleic Acids Research, Nucleic Acids Res. 2019 cited by 124
- Conditions Governing Food Protein Amyloid Fibril Formation. Part II: Milk and Legume Proteins
Authors: Marlies A. Lambrecht, Koen J.A. Jansens, Ine Rombouts, Kristof Brijs, Frédéric Rousseau, Joost Schymkowitz, Jan A. Delcour - Comprehensive Reviews in Food Science and Food Safety 2019 cited by 105
- Gain of function of mutant p53 by coaggregation with multiple tumor suppressors
Authors: Jie Xu, Joke Reumers, José R. Couceiro, Frederik De Smet, Rodrigo Gallardo, Stanislav G. Rudyak, Ann Cornelis, Jef Rozenski, Aleksandra Zwolińska, Jean‐Christophe Marine, Diether Lambrechts, Young‐Ah Suh, Frédéric Rousseau, Joost Schymkowitz - Nature Chemical Biology 2011 cited by 538
- Medin co-aggregates with vascular amyloid-β in Alzheimer’s disease
Authors: Jessica Wagner, Karoline Degenhardt, Marleen Veit, Nikolaos Louros, Katerina Konstantoulea, Angelos Skodras, Katleen Wild, Ping Liu, Ulrike Obermüller, V. Bansal, Anupriya Dalmia, Lisa M. Häsler, Marius Lambert, Matthias De Vleeschouwer, Hannah A. Davies, Jillian Madine, Deborah Kronenberg‐Versteeg, Regina Feederle, Domenico Del Turco, K. Peter R. Nilsson, Tammaryn Lashley, Thomas Deller, Marla Gearing, Lary C. Walker, Peter Heutink, Frédéric Rousseau, Joost Schymkowitz, Mathias Jucker, Jonas J. Neher - Nature 2022 cited by 108
- Alzheimer’s-Causing Mutations Shift Aβ Length by Destabilizing γ-Secretase-Aβn Interactions
Authors: María Szaruga, Bogdan Munteanu, Sam Lismont, Sarah Veugelen, Katrien Horré, Marc Mercken, Takaomi C. Saido, Natalie S. Ryan, Tatjana De Vos, Savvas N. Savvides, Rodrigo Gallardo, Joost Schymkowitz, Frédéric Rousseau, Nick C. Fox, Carsten Hopf, Bart De Strooper, Lucía Chávez‐Gutiérrez - Cell 2017 cited by 254
- Hsp90 Mediates Membrane Deformation and Exosome Release
Authors: Elsa Lauwers, Yuchun Wang, Rodrigo Gallardo, Rob van der Kant, Emiel Michiels, Jef Swerts, Pieter Baatsen, Samantha S. Zaiter, Shelli R. McAlpine, Natalia V. Gounko, Frédéric Rousseau, Joost Schymkowitz, Patrik Verstreken - Molecular Cell 2018 cited by 193
- Structure-based machine-guided mapping of amyloid sequence space reveals uncharted sequence clusters with higher solubilities
Authors: Nikolaos Louros, Gabriele Orlando, Matthias De Vleeschouwer, Frédéric Rousseau, Joost Schymkowitz - Nature Communications 2020 cited by 94
- The mechanism of γ‐Secretase dysfunction in familial Alzheimer disease
Authors: Lucía Chávez‐Gutiérrez, Leen Bammens, Iryna Benilova, Annelies Vandersteen, Manasi Benurwar, M. Borgers, Sam Lismont, Lujia Zhou, Simon Van Cleynenbreugel, Hermann Esselmann, Jens Wiltfang, Lutgarde Serneels, Eric Karran, Harrie J. M. Gijsen, Joost Schymkowitz, Frédéric Rousseau, Kerensa Broersen, Bart De Strooper - The EMBO Journal 2012 cited by 500
- Restricted Location of PSEN2/γ-Secretase Determines Substrate Specificity and Generates an Intracellular Aβ Pool
Authors: Ragna Sannerud, Cary Esselens, Paulina Ejsmont, Rafael Mattera, Leïla Rochin, Arun Kumar Tharkeshwar, Greet De Baets, Veerle De Wever, R. Habets, Veerle Baert, Wendy Vermeire, Christine Michiels, Arjan J. Groot, Rosanne Wouters, Katleen Dillen, Katlijn Vints, Pieter Baatsen, Sebastian Munck, Rita Derua, Etienne Waelkens, Guriqbal S. Basi, Mark Mercken, Marc Vooijs, Mathieu Bollen, Joost Schymkowitz, Frédéric Rousseau, Juan S. Bonifacino, Guillaume van Niel, Bart De Strooper, Wim Annaert - Cell 2016 cited by 291
- Repurposing the Antidepressant Sertraline as SHMT Inhibitor to Suppress Serine/Glycine Synthesis–Addicted Breast Tumor Growth
Authors: Shauni Lien Geeraerts, Kim R. Kampen, Gianmarco Rinaldi, Purvi Gupta, Mélanie Planque, Nikolaos Louros, Elien Heylen, Kaat De Cremer, Katrijn De Brucker, Stijn Vereecke, Benno Verbelen, Pieter Vermeersch, Joost Schymkowitz, Frédéric Rousseau, David Cassiman, Sarah‐Maria Fendt, Arnout Voet, Bruno P.A. Cammue, Karin Thevissen, Kim De Keersmaecker - Molecular Cancer Therapeutics 2020 cited by 84
- Conditions Governing Food Protein Amyloid Fibril Formation—Part I: Egg and Cereal Proteins
Authors: Koen J.A. Jansens, Marlies A. Lambrecht, Ine Rombouts, Margarita Monge‐Morera, Kristof Brijs, Frédéric Rousseau, Joost Schymkowitz, Jan A. Delcour - Comprehensive Reviews in Food Science and Food Safety 2019 cited by 83
- Bcl-xL acts as an inhibitor of IP3R channels, thereby antagonizing Ca2+-driven apoptosis
Authors: Nicolas Rosa, Hristina Ivanova, Larry E. Wagner, Justin Kale, Rita La Rovere, Kirsten Welkenhuyzen, Nikolaos Louros, Spyridoula Karamanou, Victoria Shabardina, Irma Lemmens, Elien Vandermarliere, Kozo Hamada, Hideaki Ando, Frédéric Rousseau, Joost Schymkowitz, Jan Tavernier, Katsuhiko Mikoshiba, Anastassios Economou, David W. Andrews, Jan B. Parys, David I. Yule, Geert Bultynck - Cell Death and Differentiation 2021 cited by 83
- The Stability Effects of Protein Mutations Appear to be Universally Distributed
Authors: Nobuhiko Tokuriki, François Stricher, Joost Schymkowitz, Luís Serrano, Dan S. Tawfik - Journal of Molecular Biology 2007 cited by 466
- A graphical interface for the FoldX forcefield
Authors: Joost J. J. van Durme, Javier Delgado Blanco, Francois Stricher, Luis Serrano, Joost Schymkowitz, Frederic Rousseau - Bioinformatics, Bioinform. 2011 cited by 344
