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Jorge Ghiso

Active 1986–2024

98
Papers
19,586
Citations
79
h-index
96
i10-index

Citations

Citations per year for Jorge Ghiso1986: 1 citations1987: 12 citations1988: 12 citations1989: 14 citations1990: 23 citations1991: 31 citations1992: 53 citations1993: 95 citations1994: 140 citations1995: 136 citations1996: 136 citations1997: 124 citations1998: 118 citations1999: 125 citations2000: 251 citations2001: 193 citations2002: 280 citations2003: 206 citations2004: 287 citations2005: 214 citations2006: 267 citations2007: 206 citations2008: 279 citations2009: 328 citations2010: 308 citations2011: 311 citations2012: 331 citations2013: 216 citations2014: 211 citations2015: 214 citations2016: 205 citations2017: 231 citations2018: 185 citations2019: 469 citations2020: 545 citations2021: 466 citations2022: 368 citations2023: 289 citations2024: 356 citations2025: 180 citations2026: 1 citations

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 2,834 citing papers, 33.7% of this breakdownUnited Kingdom: 539 citing papers, 6.4% of this breakdownChina: 513 citing papers, 6.1% of this breakdownGermany: 509 citing papers, 6.1% of this breakdownItaly: 328 citing papers, 3.9% of this breakdownCanada: 297 citing papers, 3.5% of this breakdownJapan: 296 citing papers, 3.5% of this breakdownAustralia: 254 citing papers, 3% of this breakdownFrance: 250 citing papers, 3% of this breakdownSweden: 245 citing papers, 2.9% of this breakdownSpain: 186 citing papers, 2.2% of this breakdownIndia: 174 citing papers, 2.1% of this breakdown
0%33.7%Other 23.6%

Institutions

Fields

  • Medicine65.9%
  • Biochemistry, Genetics and Molecular Biology17.9%
  • Neuroscience12.1%
  • Immunology and Microbiology0.9%
  • Materials Science0.7%
  • Computer Science0.5%
  • Other2%

Topics

  • Alzheimer's disease research and treatments21.6%
  • Cholinesterase and Neurodegenerative Diseases4.2%
  • Computational Drug Discovery Methods3.9%
  • Prion Diseases and Protein Misfolding3.9%
  • Neuroinflammation and Neurodegeneration Mechanisms3.1%
  • Dementia and Cognitive Impairment Research2.4%
  • Other60.9%

Coauthors

All papers

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  1. Clearance of Alzheimer’s amyloid-β1-40 peptide from brain by LDL receptor–related protein-1 at the blood-brain barrier

    Authors: Masayoshi Shibata, Shinya Yamada, S. Ram Kumar, Miguel Calero, James R. Bading, Blas Frangione, David M. Holtzman, Carol A. Miller, Dudley K. Strickland, Jorge Ghiso, Berislav V. Zloković - Journal of Clinical Investigation 2000 cited by 1,386

  2. RAGE mediates amyloid-β peptide transport across the blood-brain barrier and accumulation in brain

    Authors: Rashid Deane, Shi Du Yan, Ram Kumar Submamaryan, Barbara LaRue, Suzana Jovanović, Elizabeth Hogg, Deborah Welch, Lawrence Manness, Chang Lin, Jin Yu, Hong Zhu, Jorge Ghiso, Blas Frangione, Alan Stern, Ann Marie Schmidt, Don Armstrong, Bernd Arnold, Birgit Liliensiek, Peter P. Nawroth, Florence M. Hofman, Mark S. Kindy, David M. Stern, Berislav V. Zloković - Nature Medicine 2003 cited by 1,397

  3. Potent Neuroprotective Properties against the Alzheimer β-Amyloid by an Endogenous Melatonin-related Indole Structure, Indole-3-propionic Acid

    Authors: Yau-Jan Chyan, Burkhard Pöeggeler, Rawhi Omar, Daniel G. Chain, Blas Frangione, Jorge Ghiso, Miguel A. Pappolla - Journal of Biological Chemistry 1999 cited by 396

  4. Exogenous Induction of Cerebral ß-Amyloidogenesis Is Governed by Agent and Host

    Authors: Melanie Meyer‐Luehmann, Janaky Coomaraswamy, Tristan Bolmont, Stephan A. Kaeser, Claudia Schaefer, Ellen Kilger, Anton Neuenschwander, Dorothée Abramowski, Pascal Frey, Anneliese L. Jaton, J. M. Vigouret, Paolo Paganetti, Dominic M. Walsh, Paul M. Mathews, Jorge Ghiso, Matthias Staufenbiel, Lary C. Walker, Mathias Jucker - Science 2006 cited by 958

  5. Amyloid ion channels: A common structural link for protein-misfolding disease

    Authors: Arjan P. Quist, Ivo Doudevski, Hai Lin, Rushana Azimova, Douglas Ng, Blas Frangione, Bruce L. Kagan, Jorge Ghiso, Ratnesh Lal - National Academy of Sciences, Proceedings of the National Academy of Sciences 2005 cited by 982

  6. Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain

    Authors: Ivan Alić, Pollyanna Goh, Aoife Murray, Erik Portelius, Eleni Gkanatsiou, Gillian Gough, Kin Y. Mok, David Koschut, Reinhard Brunmeir, Yee Jie Yeap, Niamh L. O’Brien, Jürgen Groet, Xiaowei Shao, Steven Havlicek, N. Ray Dunn, Hlin Kvartsberg, Gunnar Brinkmalm, Rosalyn Hithersay, Carla M. Startin, Sarah Hamburg, Margaret Phillips, Konstantin Pervushin, Mark Turmaine, David Wallon, Anne Rovelet‐Lecrux, Hilkka Soininen, Emanuela V. Volpi, Joanne E. Martin, Jia Nee Foo, David L. Becker, Agueda Rostagno, Jorge Ghiso, Željka Krsnik, Goran Šimić, Ivica Kostović, Dinko Mitrečić, André Strydom, Elizabeth Fisher, Frances K. Wiseman, Dean Nižetić, John Hardy, Victor L. J. Tybulewicz, Annette Karmiloff‐Smith, Paul T. Francis, Kaj Blennow, André Strydom, John Hardy, Henrik Zetterberg, Dean Nižetić, Dean Nižetić, Dean Nižetić - Molecular Psychiatry 2020 cited by 123

  7. Systemic Catabolism of Alzheimer's Aβ40 and Aβ42

    Authors: Jorge Ghiso, Marcos Shayo, Miguel Calero, Douglas Ng, Yasushi Tomidokoro, Sam Gandy, Agueda Rostagno, Blas Frangione - Journal of Biological Chemistry 2004 cited by 202

  8. The carbonic anhydrase inhibitor methazolamide prevents amyloid beta-induced mitochondrial dysfunction and caspase activation protecting neuronal and glial cells in vitro and in the mouse brain

    Authors: Silvia Fossati, Patrizia Giannoni, María E. Solesio, Sarah L. Cocklin, Erwin Cabrera, Jorge Ghiso, Agueda Rostagno - Neurobiology of Disease 2015 cited by 106

  9. Alzheimer’s amyloid β heterogeneous species differentially affect brain endothelial cell viability, blood‐brain barrier integrity, and angiogenesis

    Authors: Rebecca Parodi‐Rullán, Jorge Ghiso, Erwin Cabrera, Agueda Rostagno, Silvia Fossati - Aging Cell 2020 cited by 71

  10. Nrf2 activation through the PI3K/GSK-3 axis protects neuronal cells from Aβ-mediated oxidative and metabolic damage

    Authors: Krystal Sotolongo, Jorge Ghiso, Agueda Rostagno - Alzheimer s Research & Therapy 2020 cited by 69

  11. Sequential Amyloid-β Degradation by the Matrix Metalloproteases MMP-2 and MMP-9

    Authors: Mar Hernández‐Guillamón, S. Mawhirt, Steven P. Blais, Joan Montaner, Thomas A. Neubert, Agueda Rostagno, Jorge Ghiso - Journal of Biological Chemistry 2015 cited by 133

  12. Inhibition of Alzheimer β-Fibrillogenesis by Melatonin

    Authors: Miguel A. Pappolla, Peter Bozner, Claudio Soto, Haiyan Shao, Nickolaos K. Robakis, Michael G. Zagorski, Blas Frangione, Jorge Ghiso - Journal of Biological Chemistry 1998 cited by 335

  13. Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease

    Authors: Etsuro Matsubara, Tara Bryant‐Thomas, Javier Pacheco Quinto, Tracey L. Henry, Burkhard Pöeggeler, Donald E. Herbert, Felix Cruz-Sánchez, Yau‐Jan Chyan, Mark A. Smith, George Perry, Mikio Shoji, Kōji Abe, Anna Leone, Inge Grundke‐Ikbal, Glen L. Wilson, Jorge Ghiso, Christina Williams, Lorenzo M. Refolo, Miguel A. Pappolla - Journal of Neurochemistry 2003 cited by 333

  14. A stop-codon mutation in the BRI gene associated with familial British dementia

    Authors: Rubén Vidal, Blas Frangione, Agueda Rostagno, Simon Mead, Tamás Révész, Gordon T. Plant, Jorge Ghiso - Nature 1999 cited by 473

  15. Genetics and molecular pathogenesis of sporadic and hereditary cerebral amyloid angiopathies

    Authors: Tamás Révész, Janice L. Holton, Tammaryn Lashley, Gordon T. Plant, Blas Frangione, Agueda Rostagno, Jorge Ghiso - Acta Neuropathologica 2009 cited by 298

  16. Melatonin Reverses the Profibrillogenic Activity of Apolipoprotein E4 on the Alzheimer Amyloid Aβ Peptide

    Authors: Burkhard Pöeggeler, Leticia Miravalle, Michael G. Zagorski, Thomas Wısnıewskı, Yau‐Jan Chyan, Yongbo Zhang, Haiyan Shao, Tara Bryant‐Thomas, Rubén Vidal, Blas Frangione, Jorge Ghiso, Miguel A. Pappolla - Biochemistry 2001 cited by 151

  17. Neuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with normal aging and advancing Alzheimer's disease

    Authors: Markus Britschgi, Christopher E. Olin, Hudson Johns, Yoshiko Takeda‐Uchimura, Melburne C. LeMieux, Kaspar Rufibach, Jayakumar Rajadas, H. Zhang, Beren H. Tomooka, William H. Robinson, Christopher M. Clark, Anne M. Fagan, Douglas Galasko, David M. Holtzman, Marek Jutel, Jeffrey Kaye, Cynthia A. Lemere, Jerzy Leszek, G. Li, Elaine R. Peskind, Joseph F. Quinn, Jerome A. Yesavage, Jorge Ghiso, Tony Wyss‐Coray - National Academy of Sciences, Proceedings of the National Academy of Sciences 2009 cited by 199

  18. Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid β peptides

    Authors: Takahiko Tokuda, Miguel Calero, Etsuro Matsubara, Rubén Vidal, Asok Kumar, Bruno Permanne, Berislav V. Zloković, Jonathan D. Smith, Mary Jo LaDu, Agueda Rostagno, Blas Frangione, Jorge Ghiso - Biochemical Journal 2000 cited by 265

  19. Cerebral Amyloid Angiopathies: A Pathologic, Biochemical, and Genetic View

    Authors: Tamás Révész, Jorge Ghiso, Tammaryn Lashley, Gordon T. Plant, Agueda Rostagno, Blas Frangione, Janice L. Holton - Journal of Neuropathology & Experimental Neurology 2003 cited by 288

  20. Sporadic and Familial Cerebral Amyloid Angiopathies

    Authors: Tamás Révész, Janice L. Holton, Tammaryn Lashley, Gordon T. Plant, Agueda Rostagno, Jorge Ghiso, Blas Frangione - Brain Pathology 2002 cited by 201

  21. Fate of Cerebrospinal Fluid‐Borne Amyloid β‐Peptide: Rapid Clearance into Blood and Appreciable Accumulation by Cerebral Arteries

    Authors: Jean‐François Ghersi‐Egea, Peter D. Gorevic, Jorge Ghiso, Blas Frangione, C. S. Patlak, J. D. Fenstermacher - Journal of Neurochemistry 1996 cited by 221

  22. Circulating amyloid-β peptide crosses the blood–brain barrier in aged monkeys and contributes to Alzheimer's disease lesions

    Authors: Jasmina B. Mačkić, James R. Bading, Jorge Ghiso, Lary C. Walker, Thomas Wısnıewskı, Blas Frangione, Berislav V. Zloković - Vascular Pharmacology 2002 cited by 137

  23. N-terminally truncated Aβ4-x proteoforms and their relevance for Alzheimer’s pathophysiology

    Authors: Agueda Rostagno, Erwin Cabrera, Tammaryn Lashley, Jorge Ghiso - Translational Neurodegeneration 2022 cited by 25

  24. Production of the Alzheimer Amyloid β Protein by Normal Proteolytic Processing

    Authors: Mikio Shoji, Todd E. Golde, Jorge Ghiso, Tobun T. Cheung, Steven Estus, Lillian M. Shaffer, Xiao-Dan Cai, Deborah M. McKay, Ron Tintner, B Frangione, Steven G. Younkin - Science 1992 cited by 1,445