Lewis E. Kay
Active 1989–2025
- Also published as
- Lewis E Kay
- 249
- Papers
- 52,546
- Citations
- 130
- h-index
- 244
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology68.4%
- Medicine10.4%
- Chemistry6.2%
- Materials Science3.4%
- Immunology and Microbiology2.8%
- Physics and Astronomy2%
- Other6.8%
Topics
- Protein Structure and Dynamics12.3%
- Enzyme Structure and Function6.7%
- RNA and protein synthesis mechanisms6.1%
- RNA Research and Splicing4.5%
- Advanced NMR Techniques and Applications3.1%
- RNA modifications and cancer2.8%
- Other64.5%
Coauthors
- Julie D. Forman‐Kay43
- Ad Bax23
- D.R. Muhandiram20
- Vitali Tugarinov17
- Pramodh Vallurupalli15
- D. Flemming Hansen14
- Mitsuhiko Ikura14
- Enrico Rennella13
- Daiwen Yang11
- Nikolai R. Skrynnikov11
- Yuki Toyama11
- Dmitry M. Korzhnev10
- Kevin H. Gardner10
- Robert W. Harkness10
- Ashok Sekhar9
- Frederick W. Dahlquist9
- Guillaume Bouvignies9
- Neil A. Farrow9
- Remco Sprangers9
- Wing‐Yiu Choy9
- Dennis A. Torchia8
- Rina Rosenzweig8
- Tomasz L. Religa8
- Tony Pawson8
All papers
- Structural and hydrodynamic properties of an intrinsically disordered region of a germ cell-specific protein on phase separation
Authors: Jacob P. Brady, Patrick Farber, Ashok Sekhar, Yi‐Hsuan Lin, Rui Huang, Alaji Bah, Timothy J. Nott, Hue Sun Chan, Andrew J. Baldwin, Julie D. Forman‐Kay, Lewis E. Kay - National Academy of Sciences, Proceedings of the National Academy of Sciences 2017 cited by 587
- Phospho-dependent phase separation of FMRP and CAPRIN1 recapitulates regulation of translation and deadenylation
Authors: Tae Hun Kim, Brian Tsang, Robert M. Vernon, Nahum Sonenberg, Lewis E. Kay, Julie D. Forman‐Kay - Science 2019 cited by 377
- NMR spectroscopy captures the essential role of dynamics in regulating biomolecular function
Authors: T. Reid Alderson, Lewis E. Kay - Cell 2021 cited by 237
- Folding of an intrinsically disordered protein by phosphorylation as a regulatory switch
Authors: Alaji Bah, Robert M. Vernon, Zeba Rahman Siddiqui, Mickaël Krzeminski, Ranjith Muhandiram, Charlie W. Zhao, Nahum Sonenberg, Lewis E. Kay, Julie D. Forman‐Kay - Nature 2014 cited by 570
- Studying “Invisible” Excited Protein States in Slow Exchange with a Major State Conformation
Authors: Pramodh Vallurupalli, Guillaume Bouvignies, Lewis E. Kay - Journal of the American Chemical Society 2012 cited by 540
- Backbone Dynamics of a Free and a Phosphopeptide-Complexed Src Homology 2 Domain Studied by 15N NMR Relaxation
Authors: Neil A. Farrow, Ranjith Muhandiram, Alex U. Singer, Steven M. Pascal, Cyril M. Kay, G Gish, Steven E. Shoelson, Tony Pawson, Julie D. Forman‐Kay, Lewis E. Kay - Biochemistry 1994 cited by 2,111
- An NMR View of Protein Dynamics in Health and Disease
Authors: Ashok Sekhar, Lewis E. Kay - Annual Review of Biophysics 2019 cited by 180
- Intrinsic dynamics of an enzyme underlies catalysis
Authors: Elan Eisenmesser, Óscar Millet, Wladimir Labeikovsky, Dmitry M. Korzhnev, Magnus Wolf‐Watz, Daryl A. Bosco, Jack J. Skalicky, Lewis E. Kay, Dorothee Kern - Nature 2005 cited by 1,118
- Cross-Correlated Relaxation Enhanced 1H−13C NMR Spectroscopy of Methyl Groups in Very High Molecular Weight Proteins and Protein Complexes
Authors: Vitali Tugarinov, Peter M. Hwang, Jason E. Ollerenshaw, Lewis E. Kay - Journal of the American Chemical Society 2003 cited by 653
- Interaction hot spots for phase separation revealed by NMR studies of a CAPRIN1 condensed phase
Authors: Tae Hun Kim, Brandon J. Payliss, Michael L. Nosella, Ian T. W. Lee, Yuki Toyama, Julie D. Forman‐Kay, Lewis E. Kay - National Academy of Sciences, Proceedings of the National Academy of Sciences 2021 cited by 116
- Structure of an Intermediate State in Protein Folding and Aggregation
Authors: Philipp Neudecker, Paul Robustelli, Andrea Cavalli, P.J. Walsh, Patrik Lundström, Arash Zarrine‐Afsar, Simon Sharpe, Michele Vendruscolo, Lewis E. Kay - Science 2012 cited by 406
- Poly(ADP-ribosyl)ation enhances nucleosome dynamics and organizes DNA damage repair components within biomolecular condensates
Authors: Michael L. Nosella, Tae Hun Kim, Shuya Kate Huang, Robert W. Harkness, Monica M. Goncalves, Alisia Pan, Maria Tereshchenko, Siavash Vahidi, John L. Rubinstein, Hyun O. Lee, Julie D. Forman‐Kay, Lewis E. Kay - Molecular Cell 2024 cited by 44
- Disrupting the α-synuclein-ESCRT interaction with a peptide inhibitor mitigates neurodegeneration in preclinical models of Parkinson’s disease
Authors: Satra Nim, Darren M. O’Hara, Carles Corbi‐Verge, Albert Perez‐Riba, Kazuko Fujisawa, Minesh Kapadia, Hien Chau, Federica Albanese, Grishma Pawar, Mitchell L. de Snoo, Sophie G. Ngana, Ji‐Sun Kim, Omar M. A. El‐Agnaf, Enrico Rennella, Lewis E. Kay, Suneil K. Kalia, Lorraine V. Kalia, Philip M. Kim - Nature Communications 2023 cited by 48
- Backbone dynamics of proteins as studied by nitrogen-15 inverse detected heteronuclear NMR spectroscopy: application to staphylococcal nuclease
Authors: Lewis E. Kay, Dennis A. Torchia, Ad Bax - Biochemistry 1989 cited by 1,792
- Design of amyloidogenic peptide traps
Authors: Danny D. Sahtoe, Ewa A. Andrzejewska, Hannah L. Han, Enrico Rennella, Matthias M. Schneider, Georg Meisl, Maggie Ahlrichs, Justin Decarreau, Hannah Nguyen, Alex Kang, Paul M. Levine, Mila Lamb, Xinting Li, Asim K. Bera, Lewis E. Kay, Tuomas P. J. Knowles, David Baker - Nature Chemical Biology 2024 cited by 39
- Isotope labeling strategies for the study of high-molecular-weight proteins by solution NMR spectroscopy
Authors: Vitali Tugarinov, Voula Kanelis, Lewis E. Kay - Nature Protocols 2006 cited by 540
- Dynamic equilibrium engagement of a polyvalent ligand with a single-site receptor
Authors: Tanja Mittag, Stephen Orlicky, Wing‐Yiu Choy, Xiaojing Tang, Hong Lin, Frank Sicheri, Lewis E. Kay, Mike Tyers, Julie D. Forman‐Kay - National Academy of Sciences, Proceedings of the National Academy of Sciences 2008 cited by 343
- An Improved 15N Relaxation Dispersion Experiment for the Measurement of Millisecond Time-Scale Dynamics in Proteins
Authors: D. Flemming Hansen, Pramodh Vallurupalli, Lewis E. Kay - The Journal of Physical Chemistry B 2007 cited by 239
- Mapping the per-residue surface electrostatic potential of CAPRIN1 along its phase-separation trajectory
Authors: Yuki Toyama, Atul Rangadurai, Julie D. Forman‐Kay, Lewis E. Kay - National Academy of Sciences, Proceedings of the National Academy of Sciences 2022 cited by 60
- Correlating histone acetylation with nucleosome core particle dynamics and function
Authors: Tae Hun Kim, Michael L. Nosella, Nicolas Bolik-Coulon, Robert W. Harkness, Shuya Kate Huang, Lewis E. Kay - National Academy of Sciences, Proceedings of the National Academy of Sciences 2023 cited by 41
- Probing conformational dynamics in biomolecules via chemical exchange saturation transfer: a primer
Authors: Pramodh Vallurupalli, Ashok Sekhar, Tairan Yuwen, Lewis E. Kay - Journal of Biomolecular NMR 2017 cited by 163
- A processive rotary mechanism couples substrate unfolding and proteolysis in the ClpXP degradation machinery
Authors: Zev A. Ripstein, Siavash Vahidi, Walid A. Houry, John L. Rubinstein, Lewis E. Kay - eLife 2020 cited by 125
- New Tools Provide New Insights in NMR Studies of Protein Dynamics
Authors: Anthony Mittermaier, Lewis E. Kay - Science 2006 cited by 790
- NMR spectroscopy brings invisible protein states into focus
Authors: Andrew J. Baldwin, Lewis E. Kay - Nature Chemical Biology 2009 cited by 430
