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Manolis Pasparakis

Active 1995–2026

142
Papers
36,123
Citations
97
h-index
139
i10-index

Citations

Citations per year for Manolis Pasparakis1992: 2 citations1996: 3 citations1997: 48 citations1998: 76 citations1999: 120 citations2000: 125 citations2001: 141 citations2002: 168 citations2003: 153 citations2004: 168 citations2005: 188 citations2006: 262 citations2007: 238 citations2008: 296 citations2009: 358 citations2010: 368 citations2011: 398 citations2012: 383 citations2013: 405 citations2014: 431 citations2015: 442 citations2016: 529 citations2017: 558 citations2018: 577 citations2019: 1,309 citations2020: 1,741 citations2021: 1,839 citations2022: 1,539 citations2023: 1,134 citations2024: 1,661 citations2025: 921 citations2026: 18 citations1993–1995: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 4,775 citing papers, 25.1% of this breakdownChina: 3,484 citing papers, 18.3% of this breakdownGermany: 1,655 citing papers, 8.7% of this breakdownUnited Kingdom: 1,103 citing papers, 5.8% of this breakdownJapan: 687 citing papers, 3.6% of this breakdownFrance: 595 citing papers, 3.1% of this breakdownItaly: 539 citing papers, 2.8% of this breakdownAustralia: 535 citing papers, 2.8% of this breakdownCanada: 511 citing papers, 2.7% of this breakdownBelgium: 401 citing papers, 2.1% of this breakdownSwitzerland: 358 citing papers, 1.9% of this breakdownNetherlands: 350 citing papers, 1.9% of this breakdown
0%25.1%Other 21.2%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology39.5%
  • Medicine33.5%
  • Immunology and Microbiology17.7%
  • Neuroscience4.7%
  • Nursing1.1%
  • Agricultural and Biological Sciences1%
  • Other2.5%

Topics

  • Immune Response and Inflammation4.1%
  • NF-κB Signaling Pathways3.4%
  • Inflammasome and immune disorders3.3%
  • Cell death mechanisms and regulation3.2%
  • interferon and immune responses3.1%
  • Immune Cell Function and Interaction2.2%
  • Other80.7%

Coauthors

All papers

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  1. Necroptosis and its role in inflammation

    Authors: Manolis Pasparakis, Peter Vandenabeele - Nature 2015 cited by 2,148

  2. Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis

    Authors: Melanie Fritsch, Saskia Diana Günther, Robin Schwarzer, Marie‐Christine Albert, Fabian Schorn, J Paul Werthenbach, Lars M. Schiffmann, Neil Stair, Hannah Stocks, Jens M. Seeger, Mohamed Lamkanfi, Martin Krönke, Manolis Pasparakis, Hamid Kashkar - Nature 2019 cited by 1,158

  3. Synchronized renal tubular cell death involves ferroptosis

    Authors: Andreas Linkermann, Rachid Skouta, Nina Himmerkus, Shrikant R. Mulay, Christin Dewitz, Federica De Zen, Ágnes Prókai, Gabriele Zuchtriegel, Fritz Krombach, Patrick-Simon Welz, Ricardo Weinlich, Tom Vanden Berghe, Peter Vandenabeele, Manolis Pasparakis, Markus Bleich, Joel M. Weinberg, Christoph A. Reichel, Jan Hinrich Bräsen, Ulrich Kunzendorf, Hans‐Joachim Anders, Brent R. Stockwell, Douglas R. Green, Stefan Krautwald - National Academy of Sciences, Proceedings of the National Academy of Sciences 2014 cited by 1,106

  4. Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation

    Authors: Huipeng Jiao, Laurens Wachsmuth, Snehlata Kumari, Robin Schwarzer, Juan Lin, Remzi Onur Eren, Amanda Fisher, Rebecca Lane, George R. Young, George Kassiotis, William J. Kaiser, Manolis Pasparakis - Nature 2020 cited by 483

  5. FADD and Caspase-8 Regulate Gut Homeostasis and Inflammation by Controlling MLKL- and GSDMD-Mediated Death of Intestinal Epithelial Cells

    Authors: Robin Schwarzer, Huipeng Jiao, Laurens Wachsmuth, Achim Tresch, Manolis Pasparakis - Immunity 2020 cited by 286

  6. Mechanisms regulating skin immunity and inflammation

    Authors: Manolis Pasparakis, Ingo Haase, Frank O. Nestlé - Nature reviews. Immunology 2014 cited by 843

  7. RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS

    Authors: Yasushi Ito, Dimitry Ofengeim, Ayaz Najafov, Sudeshna Das, Shahram Saberi, Ying Li, Junichi Hitomi, Hong Zhu, Hongbo Chen, Lior Mayo, Jiefei Geng, Palak Amin, Judy Park DeWitt, Adnan K. Mookhtiar, Marcus A. Florez, Amanda Tomie Ouchida, Jian-Bing Fan, Manolis Pasparakis, Michelle A. Kelliher, John Ravits, Junying Yuan - Science 2016 cited by 619

  8. RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation

    Authors: Juan Lin, Snehlata Kumari, Chun Kim, Trieu-My Van, Laurens Wachsmuth, Apostolos Polykratis, Manolis Pasparakis - Nature 2016 cited by 419

  9. ADAR1 averts fatal type I interferon induction by ZBP1

    Authors: Huipeng Jiao, Laurens Wachsmuth, Simone Wolf, Juliane Lohmann, Masahiro Nagata, Göksu Gökberk Kaya, Nikos Oikonomou, Vangelis Kondylis, Manuel Rogg, Martin Diebold, Simon E. Tröder, Branko Zevnik, Marco Prinz, Christoph Schell, George R. Young, George Kassiotis, Manolis Pasparakis - Nature 2022 cited by 201

  10. Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease

    Authors: Najoua Lalaoui, Steven E. Boyden, Hirotsugu Oda, Geryl Wood, Deborah L. Stone, Diep Chau, Lin Liu, Monique Stoffels, Tobias Kratina, Kate E. Lawlor, Kristien J.M. Zaal, Patrycja Hoffmann, Nima Etemadi, Kristy Shield‐Artin, Christine Biben, Wanxia Li Tsai, Mary Blake, Hye Sun Kuehn, Dan Yang, Holly Anderton, Natasha Silke, Laurens Wachsmuth, Lixin Zheng, Natalia Sampaio Moura, David B. Beck, Gustavo Gutierrez-Cruz, Amanda K. Ombrello, Gineth Paola Pinto-Patarroyo, Andrew J. Kueh, Marco J. Herold, Cathrine Hall, Hongying Wang, Jae Jin Chae, Natalia I. Dmitrieva, Mark McKenzie, Amanda Light, Beverly Barham, Anne Jones, Tina Romeo, Qing Zhou, Ivona Aksentijevich, James C. Mullikin, Andrew J. Gross, Anthony K. Shum, Edwin D. Hawkins, Seth L. Masters, Michael J. Lenardo, Manfred Boehm, Sergio D. Rosenzweig, Manolis Pasparakis, Anne K. Voss, Massimo Gadina, Daniel L. Kastner, John Silke - Nature 2019 cited by 333

  11. Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury

    Authors: Yumiko Imai, Keiji Kuba, G. Gregory Neely, Rubina Yaghubian-Malhami, Thomas Perkmann, Geert Loo, Maria Ermolaeva, Ruud A. W. Veldhuizen, Connie Y. H. Leung, Hongliang Wang, Haolin Liu, Yang Sun, Manolis Pasparakis, Manfred Köpf, Christin Mech, Sina Bavari, Malik Peiris, Arthur S. Slutsky, Shizuo Akira, Malin Hultqvist, Rikard Holmdahl, John M. Nicholls, Chengyu Jiang, Christoph J. Binder, Josef Penninger - Cell 2008 cited by 1,367

  12. Tumour-cell-induced endothelial cell necroptosis via death receptor 6 promotes metastasis

    Authors: Boris Strilić, Lida Yang, Julián Albarrán-Juárez, Laurens Wachsmuth, Kang Han, Ulrike Müller, Manolis Pasparakis, Stefan Offermanns - Nature 2016 cited by 567

  13. RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis

    Authors: Marius Dannappel, Katerina Vlantis, Snehlata Kumari, Apostolos Polykratis, Chun Kim, Laurens Wachsmuth, Christina Eftychi, Juan Lin, Teresa Corona, Nicole Hermance, Matija Zelic, Petra Kirsch, Marijana Basic, André Bleich, Michelle A. Kelliher, Manolis Pasparakis - Nature 2014 cited by 550

  14. Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation

    Authors: Lucie Laurien, Masahiro Nagata, Hannah Schünke, Tom Delanghe, Janica L. Wiederstein, Snehlata Kumari, Robin Schwarzer, Teresa Corona, Marcus Krüger, Mathieu J.M. Bertrand, Vangelis Kondylis, Manolis Pasparakis - Nature Communications 2020 cited by 236

  15. CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair

    Authors: Sebastian Willenborg, Tina Lucas, Geert Loo, Johanna A. Knipper, Thomas Krieg, Ingo Haase, Bent Brachvogel, Matthias Hammerschmidt, András Nagy, N. Ferrara, Manolis Pasparakis, Sabine A. Eming - Blood 2012 cited by 515

  16. A brain microvasculature endothelial cell‐specific viral vector with the potential to treat neurovascular and neurological diseases

    Authors: Jakob Körbelin, Godwin Dogbevia, Stefan Michelfelder, Dirk A. Ridder, Agnes Hunger, Jan Wenzel, Henning Seismann, Melanie Lampe, Jacqueline Bannach, Manolis Pasparakis, Jürgen A. Kleinschmidt, Markus Schwaninger, Martin Trepel - EMBO Molecular Medicine 2016 cited by 264

  17. Epithelial NEMO links innate immunity to chronic intestinal inflammation

    Authors: Arianna Nenci, Christoph Becker, Andy Wullaert, Ralph Gareus, Geert Loo, Silvio Danese, Marion Huth, Alexei Nikolaev, Clemens Neufert, Blair Madison, Deborah L. Gumucio, Markus F. Neurath, Manolis Pasparakis - Nature 2007 cited by 1,071

  18. NF-κB in the regulation of epithelial homeostasis and inflammation

    Authors: Andy Wullaert, Marion Bonnet, Manolis Pasparakis - Cell Research 2010 cited by 513

  19. MK2 Phosphorylates RIPK1 to Prevent TNF-Induced Cell Death

    Authors: Isabel Jaco, Alessandro Annibaldi, Najoua Lalaoui, Rebecca Wilson, Tencho Tenev, Lucie Laurien, Chun Kim, Kunzah Jamal, Sidonie Wicky John, Gianmaria Liccardi, Diep Chau, James M. Murphy, Gabriela Brumatti, Rebecca Feltham, Manolis Pasparakis, John Silke, Pascal Meier - Molecular Cell 2017 cited by 325

  20. The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells

    Authors: Jan Wenzel, Josephine Lampe, Helge Müller‐Fielitz, Raphael Schuster, Marietta Zille, K.-M. Müller, Markus Krohn, Jakob Körbelin, Linlin Zhang, Ümit Özorhan, Vanessa Neve, Julian U. G. Wagner, Denisa Bojková, Mariana Shumliakivska, Yun Jiang, Anke Fähnrich, Fabian Ott, Valentin Sencio, Cyril Robil, Susanne Pfefferle, Florent Sauvé, Caio Fernando Ferreira Coêlho, Jonas Franz, Frauke Spiecker, Beate Lembrich, Sonja Binder, Nina Feller, Peter König, Hauke Busch, Ludovic Collin, Roberto Villaseñor, Olaf Jöhren, Hermann C. Altmeppen, Manolis Pasparakis, Stefanie Dimmeler, Jindřich Činátl, Klaus Püschel, Matija Zelic, Dimitry Ofengeim, Christine Stadelmann, François Trottein, Rubén Nogueiras, Rolf Hilgenfeld, Markus Glatzel, Vincent Prévot, Markus Schwaninger - Nature Neuroscience 2021 cited by 263

  21. SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis

    Authors: Fumiyo Ikeda, Yonathan Lissanu Deribe, Sigrid S. Skånland, Benjamin Stieglitz, Caroline Grabbe, Mirita Franz‐Wachtel, Sjoerd J. L. van Wijk, Panchali Goswami, Vanja Nagy, Janoš Terzić, Fuminori Tokunaga, Ariadne Androulidaki, Tomoko Nakagawa, Manolis Pasparakis, Kazuhiro Iwaï, John P. Sundberg, Liliana Schaefer, Katrin Rittinger, Boris Maček, Ivan Đikić - Nature 2011 cited by 758

  22. ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS–STING

    Authors: Konrad Aden, Florian Tran, Go Ito, Raheleh Sheibani‐Tezerji, Simone Lipinski, J. W. Kuiper, Markus Tschurtschenthaler, Svetlana Saveljeva, Joya Bhattacharyya, Robert Häsler, Kareen Bartsch, Anne Luzius, Marlene Jentzsch, Maren Falk‐Paulsen, Stephanie T. Stengel, Lina Welz, Robin Schwarzer, Björn Rabe, Winfried Barchet, Stefan Krautwald, Gunther Hartmann, Manolis Pasparakis, Richard S. Blumberg, Stefan Schreiber, Arthur Kaser, Philip Rosenstiel - The Journal of Experimental Medicine 2018 cited by 174

  23. FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation

    Authors: Patrick-Simon Welz, Andy Wullaert, Katerina Vlantis, Vangelis Kondylis, Vanesa Fernández‐Majada, Maria Ermolaeva, Petra Kirsch, Anja Sterner‐Kock, Geert Loo, Manolis Pasparakis - Nature 2011 cited by 605

  24. Cutting Edge: RIPK1 Kinase Inactive Mice Are Viable and Protected from TNF-Induced Necroptosis In Vivo

    Authors: Apostolos Polykratis, Nicole Hermance, Matija Zelic, Justine E. Roderick, Chun Kim, Trieu-My Van, Thomas H. Lee, Francis Ka-Ming Chan, Manolis Pasparakis, Michelle A. Kelliher - The Journal of Immunology 2014 cited by 334