Mario Castro
Active 1991–2025
- 238
- Papers
- 38,766
- Citations
- 98
- h-index
- 213
- i10-index
Citations
Citation sources
Countries
Institutions
- Harvard University0.9%
- Imperial College London0.9%
- University of Colorado Denver0.8%
- Brigham and Women's Hospital0.7%
- University of Wisconsin–Madison0.7%
- Inserm0.6%
- Other95.4%
Fields
- Medicine72.6%
- Biochemistry, Genetics and Molecular Biology9.1%
- Immunology and Microbiology8.4%
- Neuroscience1.8%
- Engineering1.1%
- Environmental Science1.1%
- Other5.9%
Topics
- Asthma and respiratory diseases19.9%
- Respiratory and Cough-Related Research5.1%
- IL-33, ST2, and ILC Pathways4.7%
- Chronic Obstructive Pulmonary Disease (COPD) Research4.6%
- Allergic Rhinitis and Sensitization3.7%
- Delphi Technique in Research3.2%
- Other58.8%
Coauthors
- Elliot Israel82
- Sally E. Wenzel81
- Eugene R. Bleecker74
- Nizar N. Jarjour63
- Serpil C. Erzurum60
- Wendy C. Moore56
- David T. Mauger49
- John V. Fahy48
- Loren C. Denlinger45
- Bruce D. Levy44
- Benjamin Gaston40
- Deborah A. Meyers40
- Stephen P. Peters39
- William W. Busse37
- Leonard B. Bacharier36
- Anne M. Fitzpatrick30
- Annette T. Hastie30
- William J. Calhoun27
- Michael C. Peters24
- Brenda R. Phillips23
- Prescott G. Woodruff23
- Suzy Comhair23
- Eric A. Hoffman22
- W. Gerald Teague22
All papers
- International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma
Authors: Kian Fan Chung, Sally E. Wenzel, Jan Brożek, Andrew Bush, Mario Castro, Peter J. Sterk, Ian M. Adcock, Eric D. Bateman, Elisabeth H. Bel, Eugene R. Bleecker, Louis‐Philippe Boulet, Christopher E. Brightling, Pascal Chanez, Sven-Erik Dahlen, Ratko Djukanović, Urs Frey, Mina Gaga, Peter G. Gibson, Qutayba Hamid, Nizar N. Jarjour, Thaís Mauad, Ronald L. Sorkness, W. Gerald Teague - European Respiratory Journal 2013 cited by 3,924
- Dupilumab Efficacy and Safety in Moderate-to-Severe Uncontrolled Asthma
Authors: Mario Castro, Jonathan Corren, Ian Pavord, Jorge Máspero, Sally E. Wenzel, Klaus F. Rabe, William W. Busse, Linda Ford, Lawrence Sher, J. Mark FitzGerald, Constance H. Katelaris, Yuji Tohda, Bingzhi Zhang, Heribert Staudinger, Gianluca Pirozzi, Nikhil Amin, Marcella Ruddy, Bolanle Akinlade, Asif Khan, Jingdong Chao, Renata Martincova, Neil M.H. Graham, Jennifer D. Hamilton, Brian N. Swanson, Neil Stahl, George D. Yancopoulos, Ariel Teper - New England Journal of Medicine 2018 cited by 1,929
- Efficacy and Safety of Dupilumab in Glucocorticoid-Dependent Severe Asthma
Authors: Klaus F. Rabe, Parameswaran Nair, Guy Brusselle, Jorge Máspero, Mario Castro, Lawrence Sher, Hongjie Zhu, Jennifer D. Hamilton, Brian N. Swanson, Asif Khan, Jingdong Chao, Heribert Staudinger, Gianluca Pirozzi, Christian Antoni, Nikhil Amin, Marcella Ruddy, Bolanle Akinlade, Neil M.H. Graham, Neil Stahl, George D. Yancopoulos, Ariel Teper - New England Journal of Medicine 2018 cited by 1,162
- Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction
Authors: Eleanor M. Dunican, Brett M. Elicker, David S. Gierada, Scott K. Nagle, Mark L. Schiebler, John D. Newell, Wilfred W. Raymond, Marrah E. Lachowicz-Scroggins, Selena Di Maio, Eric A. Hoffman, Mario Castro, Sean B. Fain, Nizar N. Jarjour, Elliot Israel, Bruce D. Levy, Serpil C. Erzurum, Sally E. Wenzel, Deborah A. Meyers, Eugene R. Bleecker, Brenda R. Phillips, David T. Mauger, Erin Gordon, Prescott G. Woodruff, Michael C. Peters, John V. Fahy - Journal of Clinical Investigation 2018 cited by 598
- Reslizumab for inadequately controlled asthma with elevated blood eosinophil counts: results from two multicentre, parallel, double-blind, randomised, placebo-controlled, phase 3 trials
Authors: Mario Castro, James Zangrilli, Michael E. Wechsler, Eric D. Bateman, Guy Brusselle, Philip G. Bardin, Kevin Murphy, Jorge Máspero, Christopher O’Brien, Stephanie Korn - The Lancet Respiratory Medicine 2015 cited by 1,173
- Identification of Asthma Phenotypes Using Cluster Analysis in the Severe Asthma Research Program
Authors: Wendy C. Moore, Deborah A. Meyers, Sally E. Wenzel, W. Gerald Teague, Huashi Li, Xingnan Li, Ralph B. D’Agostino, Mario Castro, Douglas Curran‐Everett, Anne M. Fitzpatrick, Benjamin Gaston, Nizar N. Jarjour, Ronald L. Sorkness, William J. Calhoun, Kian Fan Chung, Suzy Comhair, Raed A. Dweik, Elliot Israel, Stephen P. Peters, William W. Busse, Serpil C. Erzurum, Eugene R. Bleecker - American Journal of Respiratory and Critical Care Medicine 2009 cited by 2,124
- Management of severe asthma: a European Respiratory Society/American Thoracic Society guideline
Authors: Fernando Holguín, Juan Carlos Cardet, Kian Fan Chung, Sarah Diver, Diogenes S. Ferreira, Anne M. Fitzpatrick, Mina Gaga, Liz Kellermeyer, Sandhya Khurana, Shandra L. Knight, Vanessa M. McDonald, Rebecca L. Morgan, Victor E. Ortega, David Rigau, Padmaja Subbarao, Thomy Tonia, Ian M. Adcock, Eugene R. Bleecker, Christopher E. Brightling, Louis‐Philippe Boulet, Michael D. Cabana, Mario Castro, Pascal Chanez, Adnan Čustović, Ratko Djukanović, Urs Frey, Betty Frankemölle, Peter G. Gibson, Dominique Hamerlijnck, Nizar N. Jarjour, Satoshi Konno, Huahao Shen, Cathy Vitary, Andy Bush - European Respiratory Journal 2019 cited by 614
- Role of Biologics in Asthma
Authors: M.C. McGregor, James G. Krings, Parameswaran Nair, Mario Castro - American Journal of Respiratory and Critical Care Medicine 2018 cited by 429
- Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting β2 agonist: a randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial
Authors: Sally E. Wenzel, Mario Castro, Jonathan Corren, Jorge Máspero, Lin Wang, Bingzhi Zhang, Gianluca Pirozzi, E. Rand Sutherland, Robert R. Evans, Vijay N. Joish, Laurent Eckert, Neil M.H. Graham, Neil Stahl, George D. Yancopoulos, Mariana Louis‐Tisserand, Ariel Teper - The Lancet 2016 cited by 880
- Plasma interleukin-6 concentrations, metabolic dysfunction, and asthma severity: a cross-sectional analysis of two cohorts
Authors: Michael C. Peters, Kelly Wong McGrath, Gregory A. Hawkins, Annette T. Hastie, Bruce D. Levy, Elliot Israel, Brenda R. Phillips, David T. Mauger, Suzy Comhair, Serpil C. Erzurum, Mats W. Johansson, Nizar N. Jarjour, Andrea M. Coverstone, Mario Castro, Fernando Holguín, Sally E. Wenzel, Prescott G. Woodruff, Eugene R. Bleecker, John V. Fahy - The Lancet Respiratory Medicine 2016 cited by 535
- Understanding the key issues in the treatment of uncontrolled persistent asthma with type 2 inflammation
Authors: William W. Busse, Monica Kraft, Klaus F. Rabe, Yamo Deniz, Paul J. Rowe, Marcella Ruddy, Mario Castro - European Respiratory Journal 2021 cited by 160
- Extracellular DNA, Neutrophil Extracellular Traps, and Inflammasome Activation in Severe Asthma
Authors: Marrah E. Lachowicz-Scroggins, Eleanor M. Dunican, Annabelle R. Charbit, Wilfred W. Raymond, Mark R. Looney, Michael C. Peters, Erin Gordon, Prescott G. Woodruff, Emma Lefrançais, Brenda R. Phillips, David T. Mauger, Suzy Comhair, Serpil C. Erzurum, Mats W. Johansson, Nizar N. Jarjour, Andrea M. Coverstone, Mario Castro, Annette T. Hastie, Eugene R. Bleecker, Merritt L. Fajt, Sally E. Wenzel, Elliot Israel, Bruce D. Levy, John V. Fahy - American Journal of Respiratory and Critical Care Medicine 2019 cited by 269
- Long-term safety and efficacy of dupilumab in patients with moderate-to-severe asthma (TRAVERSE): an open-label extension study
Authors: Michael E Wechsler, Linda B Ford, Jorge F Maspero, Ian D Pavord, Alberto Papi, Arnaud Bourdin, Henrik Watz, Mario Castro, Natalia M Nenasheva, Yuji Tohda, David Langton, Guido Cardona, Christian Domingo, Hae Sim Park, Kenneth R Chapman, Xuezhou Mao, Yi Zhang, Asif H Khan, Yamo Deniz, Paul J Rowe, Upender Kapoor, Faisal A Khokhar, Leda P Mannent, Marcella Ruddy, Elizabeth Laws, Nikhil Amin, Megan Hardin - The Lancet Respiratory Medicine 2021 cited by 219
- Neutrophil cytoplasts induce T H 17 differentiation and skew inflammation toward neutrophilia in severe asthma
Authors: Nandini Krishnamoorthy, David N. Douda, Thayse R. Brüggemann, Isabell Ricklefs, Melody G. Duvall, Raja-Elie E. Abdulnour, Kimberly Martinod, Luciana P. Tavares, Xiao Wang, Manuela Cernadas, Elliot Israel, David T. Mauger, Eugene R. Bleecker, Mario Castro, Serpil C. Erzurum, Benjamin Gaston, Nizar N. Jarjour, Sally E. Wenzel, Eleanor M. Dunican, John V. Fahy, Daniel Irimia, Denisa D. Wagner, Bruce D. Levy - Science Immunology 2018 cited by 238
- Mucus Plugs Persist in Asthma, and Changes in Mucus Plugs Associate with Changes in Airflow over Time
Authors: Monica Tang, Brett M. Elicker, Travis S. Henry, David S. Gierada, Mark L. Schiebler, Brendan K. Huang, Michael C. Peters, Mario Castro, Eric A. Hoffman, Sean B. Fain, Samuel Y. Ash, Jiwoong Choi, Chase Hall, Brenda R. Phillips, David T. Mauger, Loren C. Denlinger, Nizar N. Jarjour, Elliot Israel, Wanda Phipatanakul, Bruce D. Levy, Sally E. Wenzel, Eugene R. Bleecker, Prescott G. Woodruff, John V. Fahy, Eleanor M. Dunican - American Journal of Respiratory and Critical Care Medicine 2022 cited by 141
- Features of the bronchial bacterial microbiome associated with atopy, asthma, and responsiveness to inhaled corticosteroid treatment
Authors: Juliana Durack, Susan V. Lynch, Snehal Nariya, Nirav R. Bhakta, Avraham Beigelman, Mario Castro, Anne-Marie Dyer, Elliot Israel, Monica Kraft, Richard J. Martin, David T. Mauger, Sharon R Rosenberg, Tonya Sharp-King, Steven R. White, Prescott G. Woodruff, Pedro C. Avila, Loren C. Denlinger, Fernando Holguín, Stephen C. Lazarus, Njira Lugogo, Wendy C. Moore, Stephen P. Peters, Loretta G. Que, Lewis J. Smith, Christine A. Sorkness, Michael E. Wechsler, Sally E. Wenzel, Homer A. Boushey, Yvonne J. Huang - Journal of Allergy and Clinical Immunology 2016 cited by 308
- Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma
Authors: Yvonne J. Huang, Craig E. Nelson, Eoin Brodie, Todd Z. DeSantis, Marshall Baek, Jane Liu, Tanja Woyke, Martin Allgaier, Jim Bristow, Jeanine P. Wiener-Kronish, E. Rand Sutherland, Tonya S. King, Nikolina Icitovic, Richard J. Martin, William J. Calhoun, Mario Castro, Loren C. Denlinger, Emily DiMango, Monica Kraft, Stephen P. Peters, Stephen I. Wasserman, Michael E. Wechsler, Homer A. Boushey, Susan V. Lynch - Journal of Allergy and Clinical Immunology 2010 cited by 696
- Inflammatory and Comorbid Features of Patients with Severe Asthma and Frequent Exacerbations
Authors: Loren C. Denlinger, Brenda R. Phillips, Sima Ramratnam, Kristie Ross, Nirav R. Bhakta, Juan Carlos Cardet, Mario Castro, Stephen P. Peters, Wanda Phipatanakul, Shean Aujla, Leonard B. Bacharier, Eugene R. Bleecker, Suzy Comhair, Andrea M. Coverstone, Mark D. DeBoer, Serpil C. Erzurum, Sean B. Fain, Merritt L. Fajt, Anne M. Fitzpatrick, Jonathan M. Gaffin, Benjamin Gaston, Annette T. Hastie, Gregory A. Hawkins, Fernando Holguín, Anne-Marie Irani, Elliot Israel, Bruce D. Levy, Ngoc P. Ly, Deborah A. Meyers, Wendy C. Moore, Ross Myers, Maria Theresa D. Opina, Michael C. Peters, Mark L. Schiebler, Ronald L. Sorkness, W. Gerald Teague, Sally E. Wenzel, Prescott G. Woodruff, David T. Mauger, John V. Fahy, Nizar N. Jarjour - American Journal of Respiratory and Critical Care Medicine 2016 cited by 444
- Eosinophils and tissue remodeling: Relevance to airway disease
Authors: Salman Siddiqui, Claus Bachert, Leif Bjermer, Kathleen M. Buchheit, Mario Castro, Yimin Qin, Hitasha Rupani, Hironori Sagara, Peter Howarth, Camille Taillé - Journal of Allergy and Clinical Immunology 2023 cited by 109
- CCL5 is a potential bridge between type 1 and type 2 inflammation in asthma
Authors: Marc Gauthier, Sagar Kale, Timothy B. Oriss, Michael C. Gorry, Richard P. Ramonell, Kathryn R. Dalton, Prabir Ray, John V. Fahy, Max A. Seibold, Mario Castro, Nizar N. Jarjour, Benjamin Gaston, Eugene R. Bleecker, Deborah A. Meyers, Wendy C. Moore, Annette T. Hastie, Elliot Israel, Bruce D. Levy, David T. Mauger, Serpil C. Erzurum, Suzy Comhair, Sally E. Wenzel, Anuradha Ray - Journal of Allergy and Clinical Immunology 2023 cited by 61
- Reslizumab for Poorly Controlled, Eosinophilic Asthma: A Randomized, Placebo-controlled Study
Authors: Mario Castro, Sameer K. Mathur, Frederick E. Hargreave, Louis‐Philippe Boulet, Fang Xie, James B. Young, H. Jeffrey Wilkins, Timothy Henkel, Parameswaran Nair - American Journal of Respiratory and Critical Care Medicine 2011 cited by 718
- Protocols for multi‐site trials using hyperpolarized 129Xe MRI for imaging of ventilation, alveolar‐airspace size, and gas exchange: A position paper from the 129Xe MRI clinical trials consortium
Authors: Peter Niedbalski, Chase Hall, Mario Castro, Rachel L. Eddy, Jonathan H. Rayment, Sarah Svenningsen, Grace Párraga, Brandon Zanette, Giles Santyr, Robert P. Thomen, Neil J. Stewart, Guilhem Collier, Ho‐Fung Chan, Jim M. Wild, Sean B. Fain, G. Wilson Miller, Jaime F. Mata, John P. Mugler, Bastiaan Driehuys, Matthew M. Willmering, Zackary I. Cleveland, Jason C. Woods - Magnetic Resonance in Medicine 2021 cited by 102
- The upper-airway microbiota and loss of asthma control among asthmatic children
Authors: Yanjiao Zhou, Daniel J. Jackson, Leonard B. Bacharier, David T. Mauger, Homer A. Boushey, Mario Castro, Juliana Durack, Yvonne J. Huang, Robert F. Lemanske, Gregory A. Storch, George M. Weinstock, Kristine M. Wylie, Ronina Covar, Anne M. Fitzpatrick, Wanda Phipatanakul, Rachel G. Robison, Avraham Beigelman - Nature Communications 2019 cited by 157
- Genetic analyses identify GSDMB associated with asthma severity, exacerbations, and antiviral pathways
Authors: Xingnan Li, Stephanie A. Christenson, Brian D. Modena, Huashi Li, William W. Busse, Mario Castro, Loren C. Denlinger, Serpil C. Erzurum, John V. Fahy, Benjamin Gaston, Annette T. Hastie, Elliot Israel, Nizar N. Jarjour, Bruce D. Levy, Wendy C. Moore, Prescott G. Woodruff, Naftali Kaminski, Sally E. Wenzel, Eugene R. Bleecker, Deborah A. Meyers - Journal of Allergy and Clinical Immunology 2020 cited by 93
