Mark C. Chappell
Active 1988–2024
- 84
- Papers
- 18,421
- Citations
- 72
- h-index
- 83
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine81.6%
- Biochemistry, Genetics and Molecular Biology8.6%
- Neuroscience3.5%
- Immunology and Microbiology1.4%
- Computer Science1.2%
- Nursing0.7%
- Other3%
Topics
- COVID-19 Clinical Research Studies14.8%
- SARS-CoV-2 and COVID-19 Research9.3%
- Renin-Angiotensin System Studies8.5%
- Long-Term Effects of COVID-197.1%
- Hormonal Regulation and Hypertension4.7%
- Receptor Mechanisms and Signaling2.6%
- Other53%
Coauthors
- Carlos M. Ferrario40
- Debra I. Diz24
- K. Bridget Brosnihan21
- David B. Averill11
- Patricia E. Gallagher9
- TanYa M. Gwathmey9
- E. Ann Tallant7
- Hossam A. Shaltout7
- Jewell A. Jessup7
- Sarah H. Lindsey7
- Ashish K. Khanna6
- Karl D. Pendergrass6
- Andrew M. South5
- Christopher L. Schaich5
- James C. Rose5
- Nancy T. Pirro5
- Shridhar N. Iyer5
- Alicia J. Allred4
- Josef Penninger4
- Laurence W. Busse4
- Leanne Groban4
- Brian Westwood3
- Gavin Y. Oudit3
- Greg S. Martin3
All papers
- A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus–induced lung injury
Authors: Keiji Kuba, Yumiko Imai, Shuan Rao, Hong Gao, Feng Guo, Bin Guan, Yi Huan, Peng Yang, Yanli Zhang, Wei Deng, Linlin Bao, Binlin Zhang, Guang Liu, Zhong Wang, Mark C. Chappell, Yanxin Liu, Dexian Zheng, Andreas Leibbrandt, Teiji Wada, Arthur S. Slutsky, De‐Pei Liu, Chuan Qin, Chengyu Jiang, Josef Penninger - Nature Medicine 2005 cited by 3,646
- Diet, obesity, and the gut microbiome as determinants modulating metabolic outcomes in a non-human primate model
Authors: Tiffany M. Newman, Carol A. Shively, Thomas C. Register, Susan E. Appt, Hariom Yadav, Rita R. Colwell, Brian Fanelli, Manoj Dadlani, Karlis Graubics, Uyen Thao Nguyen, Sivapriya Ramamoorthy, Beth Uberseder, Kenysha Y.J. Clear, Adam S. Wilson, Kimberly D. Reeves, Mark C. Chappell, Janet A. Tooze, Katherine L. Cook - Microbiome 2021 cited by 109
- Biochemical evaluation of the renin-angiotensin system: the good, bad, and absolute?
Authors: Mark C. Chappell - American Journal of Physiology-Heart and Circulatory Physiology 2015 cited by 286
- Angiotensin-converting enzyme 2 is an essential regulator of heart function
Authors: Michael A. Crackower, Renu Sarao, Gavin Y. Oudit, Chana Yagil, I. Kozieradzki, Sam Scanga, Antonio J. Oliveira-dos-Santos, Joan da Costa, Liyong Zhang, York Pei, James W. Scholey, Carlos M. Ferrario, Armen S. Manoukian, Mark C. Chappell, Peter H. Backx, Yoram Yagil, Josef Penninger - Nature 2002 cited by 1,774
- COVID-19, ACE2, and the cardiovascular consequences
Authors: Andrew M. South, Debra I. Diz, Mark C. Chappell - American Journal of Physiology-Heart and Circulatory Physiology 2020 cited by 798
- Association of Active Renin Content With Mortality in Critically Ill Patients: A Post hoc Analysis of the Vitamin C, Thiamine, and Steroids in Sepsis (VICTAS) Trial*
Authors: Laurence W. Busse, Christopher L. Schaich, Mark C. Chappell, Michael T. McCurdy, E. Staples, Caitlin C. ten Lohuis, Jeremiah S. Hinson, Jonathan Sevransky, Richard E. Rothman, David W. Wright, Greg S. Martin, Ashish K. Khanna, on behalf of the Vitamin C, Thiamine, and Steroids in Sepsis (VICTAS) Investigators - Critical Care Medicine 2023 cited by 37
- ACE inhibitors and angiotensin receptor blockers differentially alter the response to angiotensin II treatment in vasodilatory shock
Authors: Daniel E. Leisman, Damian Handisides, Laurence W. Busse, Mark C. Chappell, Lakhmir S. Chawla, Michael R. Filbin, Marcia B. Goldberg, Kealy R. Ham, Ashish K. Khanna, Marlies Ostermann, Michael T. McCurdy, Christopher Adams, Tony N. Hodges, Rinaldo Bellomo, The ATHOS-3 Investigators - Critical Care 2024 cited by 34
- Effect of Angiotensin-Converting Enzyme Inhibition and Angiotensin II Receptor Blockers on Cardiac Angiotensin-Converting Enzyme 2
Authors: Carlos M. Ferrario, Jewell A. Jessup, Mark C. Chappell, David B. Averill, K. Bridget Brosnihan, E. Ann Tallant, Debra I. Diz, Patricia E. Gallagher - Circulation 2005 cited by 1,615
- Renin-Angiotensin System and Sex Differences in COVID-19: A Critical Assessment
Authors: Mark C. Chappell - Circulation Research 2023 cited by 31
- Role of estrogen in diastolic dysfunction
Authors: Zhuo Zhao, Hao Wang, Jewell A. Jessup, Sarah H. Lindsey, Mark C. Chappell, Leanne Groban - American Journal of Physiology-Heart and Circulatory Physiology 2014 cited by 202
- Estrogen Receptor GPR30 Reduces Oxidative Stress and Proteinuria in the Salt-Sensitive Female mRen2.Lewis Rat
Authors: Sarah H. Lindsey, Liliya M. Yamaleyeva, K. Bridget Brosnihan, Patricia E. Gallagher, Mark C. Chappell - Hypertension 2011 cited by 113
- Vasodilation by GPER in mesenteric arteries involves both endothelial nitric oxide and smooth muscle cAMP signaling
Authors: Sarah H. Lindsey, Liu Liu, Mark C. Chappell - Steroids 2013 cited by 110
- Concerns on the Specificity of Commercial ELISAs for the Measurement of Angiotensin (1–7) and Angiotensin II in Human Plasma
Authors: Mark C. Chappell, Nancy T. Pirro, Andrew M. South, TanYa M. Gwathmey - Hypertension 2021 cited by 55
- Renin in critically ill patients
Authors: Yuki Kotani, Mark C. Chappell, Giovanni Landoni, Alexander Zarbock, Rinaldo Bellomo, Ashish K. Khanna - Annals of Intensive Care 2024 cited by 17
- Counterregulatory Actions of Angiotensin-(1-7)
Authors: Carlos M. Ferrario, Mark C. Chappell, E. Ann Tallant, K. Bridget Brosnihan, Debra I. Diz - Hypertension 1997 cited by 511
- Estrogen Regulation of Angiotensin-Converting Enzyme mRNA
Authors: Patricia E. Gallagher, Ping Li, John R. Lenhart, Mark C. Chappell, K. Bridget Brosnihan - Hypertension 1999 cited by 290
- Angiotensin-(1–7) Prevents Activation of NADPH Oxidase and Renal Vascular Dysfunction in Diabetic Hypertensive Rats
Authors: Ibrahim F. Benter, Mariam H.M. Yousif, Gursev S. Dhaunsi, Jaspal Kaur, Mark C. Chappell, Debra I. Diz - American Journal of Nephrology 2007 cited by 202
- Update on the Angiotensin Converting Enzyme 2-Angiotensin (1–7)-Mas Receptor Axis: Fetal Programing, Sex Differences, and Intracellular Pathways
Authors: Mark C. Chappell, Allyson C. Marshall, Ebaa M Alzayadneh, Hossam A. Shaltout, Debra I. Diz - Frontiers in Endocrinology 2014 cited by 196
- Nonclassical Renin‐Angiotensin System and Renal Function
Authors: Mark C. Chappell - Comprehensive physiology 2012 cited by 130
- Ectodomain shedding of angiotensin converting enzyme 2 in human airway epithelia
Authors: Hong Peng Jia, Dwight C. Look, Ping Tan, Lei Shi, Melissa A. Hickey, Lokesh Gakhar, Mark C. Chappell, Christine Wohlford-Lenane, Paul B. McCray - American Journal of Physiology-Lung Cellular and Molecular Physiology 2009 cited by 345
- Metabolism of Angiotensin-(1–7) by Angiotensin-Converting Enzyme
Authors: Mark C. Chappell, Nancy T. Pirro, Angela Sykes, Carlos M. Ferrario - Hypertension 1998 cited by 291
- Identification of angiotensin-(1-7) in rat brain
Authors: Mark C. Chappell, K. Bridget Brosnihan, Debra I. Diz, Carlos M. Ferrario - Journal of Biological Chemistry 1989 cited by 211
- Converting enzyme activity and angiotensin metabolism in the dog brainstem.
Authors: Robson A.S. Santos, K. Bridget Brosnihan, Mark C. Chappell, Jorge L. Pesquero, Cheryl L. Chernicky, Lewis Joel Greene, Carlos M. Ferrario - Hypertension 1988 cited by 183
- Chronic Treatment with the G Protein-Coupled Receptor 30 Agonist G-1 Decreases Blood Pressure in Ovariectomized mRen2.Lewis Rats
Authors: Sarah H. Lindsey, Jonathan Cohen, K. Bridget Brosnihan, Patricia E. Gallagher, Mark C. Chappell - Endocrinology 2009 cited by 180
