Mark E. Gurney
Active 1980–2025
- 83
- Papers
- 22,892
- Citations
- 63
- h-index
- 79
- i10-index
Citations
Citation sources
Countries
Institutions
- Harvard University1.6%
- Johns Hopkins University1.1%
- Massachusetts General Hospital0.9%
- Johns Hopkins Medicine0.7%
- Inserm0.7%
- Brigham and Women's Hospital0.6%
- Other94.4%
Fields
- Medicine54.7%
- Biochemistry, Genetics and Molecular Biology27.9%
- Neuroscience8.7%
- Immunology and Microbiology3.8%
- Computer Science1.3%
- Nursing1.3%
- Other2.3%
Topics
- Amyotrophic Lateral Sclerosis Research9.3%
- Alzheimer's disease research and treatments6.7%
- Neurogenetic and Muscular Disorders Research5%
- Cholinesterase and Neurodegenerative Diseases3.6%
- Parkinson's Disease Mechanisms and Treatments2.9%
- Computational Drug Discovery Methods2.2%
- Other70.3%
Coauthors
- Michael O’Dwyer7
- Rong Xu6
- Abhishek A. Mangaonkar5
- Ayalew Tefferi5
- Edward D. Hall5
- Pamela B. Davis5
- Alex B. Burgin4
- Aref Al‐Kali4
- Christy M. Finke4
- George Perry4
- Mithun Vinod Shah4
- Mrinal M. Patnaik4
- Ping Zhai4
- Timothy J. Fleck4
- Xin Qi4
- Adele M. Pauley3
- Andrei Manolescu3
- Anmol Baranwal3
- Augustine Kong3
- David C. Kaelber3
- Guðmar Þorleifsson3
- Guðmundur Þorgeirsson3
- Hassan B. Alkhateeb3
- J. J. Singh3
All papers
- Motor Neuron Degeneration in Mice that Express a Human Cu,Zn Superoxide Dismutase Mutation
Authors: Mark E. Gurney, Haifeng Pu, Arlene Y. Chiu, Mauro C. Dal Canto, Cynthia Y. Polchow, Denise D. Alexander, Jan Caliendo, Afif Hentati, Young W. Kwon, Han‐Xiang Deng, Wenje Chen, Ping Zhai, Robert Sufit, Teepu Siddique - Science 1994 cited by 4,158
- Associations of semaglutide with first‐time diagnosis of Alzheimer's disease in patients with type 2 diabetes: Target trial emulation using nationwide real‐world data in the US
Authors: William Yang Wang, QuangQiu Wang, Xin Qi, Mark E. Gurney, George Perry, Nora D. Volkow, Pamela B. Davis, David C. Kaelber, Rong Xu - Alzheimer s & Dementia 2024 cited by 141
- Inhibition of phosphodiesterase-4D in adults with fragile X syndrome: a randomized, placebo-controlled, phase 2 clinical trial
Authors: Elizabeth Berry‐Kravis, Mark Harnett, Scott A. Reines, Melody Reese, Lauren E. Ethridge, Abigail H. Outterson, Claire Michalak, Jeremiah Furman, Mark E. Gurney - Nature Medicine 2021 cited by 131
- CD38 knockout natural killer cells expressing an affinity optimized CD38 chimeric antigen receptor successfully target acute myeloid leukemia with reduced effector cell fratricide
Authors: Mark E. Gurney, Arwen Stikvoort, Emma Nolan, Lucy Kirkham-McCarthy, Stanislav Khoruzhenko, Rama Shivakumar, Sonja Zweegman, Niels W.C.J. van de Donk, Tuna Mutis, Éva Szegezdi, Subhashis Sarkar, Michael O’Dwyer - Haematologica 2020 cited by 110
- Tumor Necrosis Factor (TNF) blocking agents are associated with lower risk for Alzheimer’s disease in patients with rheumatoid arthritis and psoriasis
Authors: Mengshi Zhou, Rong Xu, David C. Kaelber, Mark E. Gurney - PLoS ONE 2020 cited by 153
- COVID‐19 and dementia: Analyses of risk, disparity, and outcomes from electronic health records in the US
Authors: QuanQiu Wang, Pamela B. Davis, Mark E. Gurney, Rong Xu - Alzheimer s & Dementia 2021 cited by 273
- A variant in CDKAL1 influences insulin response and risk of type 2 diabetes
Authors: Valgerður Steinthórsdóttir, Guðmar Þorleifsson, Inga Reynisdóttir, Rafn Benediktsson, Þorbjörg Jónsdóttir, G. Bragi Walters, Unnur Styrkársdóttir, Sólveig Grétarsdóttir, Valur Emilsson, Shyamali Ghosh, Adam Baker, Steinunn Snorradóttir, Hjördis Bjarnason, Maggie Ng, Torben Hansen, Yu Z. Bagger, Robert L. Wilensky, Muredach P. Reilly, Adebowale Adeyemo, Yuanxiu Chen, Jie Zhou, Vilmundur Guðnason, Guanjie Chen, Hanxia Huang, Kerrie Lashley, Ayo P. Doumatey, Wing‐Yee So, Ronald C.W., Gitte Andersen, Knut Borch‐Johnsen, Torben Jørgensen, Jana V. van Vliet‐Ostaptchouk, Marten H. Hofker, Cisca Wijmenga, Claus Christiansen, Daniel J. Rader, Charles N. Rotimi, Mark E. Gurney, Juliana C.N. Chan, Oluf Pedersen, Gunnar Sigurðsson, Jeffrey R. Gulcher, Unnur Þorsteinsdóttir, Augustine Kong, Kāri Stefánsson - Nature Genetics 2007 cited by 1,085
- Concurrent transposon engineering and CRISPR/Cas9 genome editing of primary CLL-1 chimeric antigen receptor–natural killer cells
Authors: Mark E. Gurney, Eimear O’Reilly, Sarah Corcoran, Sarah Brophy, Janusz Krawczyk, Neil Otto, David Hermanson, Richard Childs, Éva Szegezdi, Michael O’Dwyer - Cytotherapy 2022 cited by 38
- Design of phosphodiesterase 4D (PDE4D) allosteric modulators for enhancing cognition with improved safety
Authors: Alex B. Burgin, Ólafur Þ. Magnússon, Jasbir Singh, Pam Witte, Bart L. Staker, Jón Már Björnsson, Margrét Þorsteinsdóttir, Sigrún Hrafnsdóttir, Timothy J. Hagen, Alex S. Kiselyov, Lance Stewart, Mark E. Gurney - Nature Biotechnology 2009 cited by 394
- Features and Factors Associated With Myeloid Neoplasms After Chimeric Antigen Receptor T-Cell Therapy
Authors: Mark E. Gurney, Anmol Baranwal, Allison Rosenthal, Mohamed A. Kharfan‐Dabaja, Saad S. Kenderian, Yi Lin, Mithun Vinod Shah - JAMA Oncology 2024 cited by 24
- Feeder Cells at the Interface of Natural Killer Cell Activation, Expansion and Gene Editing
Authors: Mark E. Gurney, Soumyadipta Kundu, Shubham Pandey, Michael O’Dwyer - Frontiers in Immunology 2022 cited by 47
- Membrane-anchored aspartyl protease with Alzheimer's disease β-secretase activity
Authors: Riqiang Yan, Michael J. Bienkowski, Mary E. Shuck, Huiyi Miao, Monica C. Tory, Adele M. Pauley, John R. Brashler, Nancy C. Stratman, W. Rodney Mathews, Allen E. Buhl, Donald B. Carter, Alfredo G. Tomasselli, L. Parodi, Robert L. Heinrikson, Mark E. Gurney - Nature 1999 cited by 1,434
- Phosphodiesterase-4 (PDE4) Molecular Pharmacology and Alzheimer's Disease
Authors: Mark E. Gurney, Emily C. D’Amato, Alex B. Burgin - Neurotherapeutics 2014 cited by 118
- Design and Synthesis of Selective Phosphodiesterase 4D (PDE4D) Allosteric Inhibitors for the Treatment of Fragile X Syndrome and Other Brain Disorders
Authors: Mark E. Gurney, Richard A. Nugent, Xuesheng Mo, Janice A. Sindac, Timothy J. Hagen, David Fox, James M. O’Donnell, Chong Zhang, Ying Xu, Han‐Ting Zhang, Vincent E. Groppi, Marc B. Bailie, Ronald E. White, Donna L. Romero, A. Samuel Vellekoop, Joel R. Walker, Matthew D. Surman, Lei Zhu, Robert F. Campbell - Journal of Medicinal Chemistry 2019 cited by 74
- Realizing Innate Potential: CAR-NK Cell Therapies for Acute Myeloid Leukemia
Authors: Mark E. Gurney, Michael O’Dwyer - Cancers 2021 cited by 37
- Gut–microbiota–microglia–brain interactions in Alzheimer’s disease: knowledge-based, multi-dimensional characterization
Authors: QuanQiu Wang, Pamela B. Davis, Xin Qi, Shu G. Chen, Mark E. Gurney, George Perry, P. Murali Doraiswamy, Rong Xu - Alzheimer s Research & Therapy 2021 cited by 32
- aph-1 and pen-2 Are Required for Notch Pathway Signaling, γ-Secretase Cleavage of βAPP, and Presenilin Protein Accumulation
Authors: Ross S. Francis, Garth McGrath, Jianhua Zhang, David A. Ruddy, Mary Sym, Javier Apfeld, Monique Nicoll, Mark Maxwell, Bing Hai, Michael C. Ellis, Annette L. Parks, Wei Xu, Jinhe Li, Mark E. Gurney, Richard L. Myers, Carol S. Himes, Ronald R. Hiebsch, Cara Ruble, Jeffrey S. Nye, Daniel Curtis - Developmental Cell 2002 cited by 796
- Potential long‐term effect of tumor necrosis factor inhibitors on dementia risk: A propensity score matched retrospective cohort study in US veterans
Authors: Chunlei Zheng, Nathanael R. Fillmore, Jaime Ramos‐Cejudo, Mary T. Brophy, Ricardo S. Osorio, Mark E. Gurney, Wei Qiao Qiu, Rhoda Au, George Perry, Maureen Dubreuil, Shu G. Chen, Xin Qi, Pamela B. Davis, Nhan Do, Rong Xu - Alzheimer s & Dementia 2021 cited by 26
- PDE4 subtypes in cancer
Authors: Samuel H. Lai, Guston Zervoudakis, Jesse Chou, Mark E. Gurney, Kelly M. Quesnelle - Oncogene 2020 cited by 99
- Generating natural killer cells for adoptive transfer: expanding horizons
Authors: Soumyadipta Kundu, Mark E. Gurney, Michael O’Dwyer - Cytotherapy 2021 cited by 76
- Neuregulin 1 and Susceptibility to Schizophrenia
Authors: Hreinn Stefánsson, Hannes Pétursson, Engilbert Sigurðsson, Valgerður Steinthórsdóttir, Soley Bjornsdottir, Thordur Sigmundsson, Shyamali Ghosh, Jon Brynjolfsson, Steinunn Gunnarsdottir, Omar Ivarsson, Thomas T. Chou, Ómar Hjaltason, Birgitta Birgisdottir, Helgi Jónsson, Vala G Gudnadottir, Elsa Gudmundsdottir, Ásgeir Björnsson, Brynjolfur Ingvarsson, Andrés Ingason, Sigmundur Sigfússon, Hrönn Harðardóttir, Richard P. Harvey, Donna Lai, Mingdong Zhou, Daniela Brunner, Vincent Mutel, Acuna Gonzalo, Greg Lemke, Jesús Sainz, G Jóhannesson, Þorkell Andrésson, Daníel F. Guðbjartsson, Andrei Manolescu, Michael L. Frigge, Mark E. Gurney, Augustine Kong, Jeffrey R. Gulcher, Kāri Stefánsson - The American Journal of Human Genetics 2002 cited by 1,689
- Formation of high molecular weight complexes of mutant Cu,Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis
Authors: Jennifer Johnston, Muffie J. Dalton, Mark E. Gurney, Ron R. Kopito - National Academy of Sciences, Proceedings of the National Academy of Sciences 2000 cited by 599
- Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions.
Authors: Pang‐Hsien Tu, P Raju, Kent A. Robinson, Mark E. Gurney, John Q. Trojanowski, V M Lee - National Academy of Sciences, Proceedings of the National Academy of Sciences 1996 cited by 412
- Structural basis for the design of selective phosphodiesterase 4B inhibitors
Authors: David Fox, Alex B. Burgin, Mark E. Gurney - Cellular Signalling 2013 cited by 104
