Mark W. Dewhirst
Active 1984–2025
- 196
- Papers
- 48,668
- Citations
- 120
- h-index
- 194
- i10-index
Citations
Citation sources
Countries
Institutions
- Harvard University0.9%
- Duke Medical Center0.8%
- Duke University0.8%
- The University of Texas MD Anderson Cancer Center0.6%
- Johns Hopkins University0.6%
- Inserm0.6%
- Other95.7%
Fields
- Biochemistry, Genetics and Molecular Biology41.7%
- Medicine33.3%
- Engineering9.5%
- Materials Science7.7%
- Immunology and Microbiology2.8%
- Neuroscience1.4%
- Other3.6%
Topics
- Cancer, Hypoxia, and Metabolism8.2%
- Cancer Cells and Metastasis3.7%
- Nanoplatforms for cancer theranostics3.4%
- Nanoparticle-Based Drug Delivery3%
- Glioma Diagnosis and Treatment2.7%
- Angiogenesis and VEGF in Cancer2.5%
- Other76.5%
Coauthors
- Željko Vujašković24
- Timothy W. Secomb20
- David M. Brizel18
- Zahid N. Rabbani18
- Rod D. Braun17
- Benjamin J. Moeller13
- Thaddeus V. Samulski12
- Thies Schroeder11
- Chuan‐Yuan Li10
- Daohai Yu10
- David Needham10
- Leonard R. Prosnitz10
- Siqing Shan10
- Yiting Cao10
- James R. Oleson9
- Zishan A. Haroon9
- Benjamin L. Viglianti8
- Bruce Klitzman8
- Fan Yuan8
- Gary L. Rosner8
- Mitchell S. Anscher8
- Richard Hsu8
- Allison Betof Warner7
- Donald Ε. Thrall7
All papers
- Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
Authors: Shideng Bao, Qiulian Wu, Roger E. McLendon, Yueling Hao, Qing Shi, Anita B. Hjelmeland, Mark W. Dewhirst, Darell D. Bigner, Jeremy N. Rich - Nature 2006 cited by 6,427
- Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice
Authors: Pierre Sonveaux, Frédérique Végran, Thies Schroeder, Melanie Wergin, Julien Verrax, Zahid N. Rabbani, Christophe J. De Saedeleer, Kelly M. Kennedy, Caroline Diepart, Bénédicte F. Jordan, Michael J. Kelley, Bernard Gallez, M Wahl, Olivier Féron, Mark W. Dewhirst - Journal of Clinical Investigation 2008 cited by 1,611
- Transport of drugs from blood vessels to tumour tissue
Authors: Mark W. Dewhirst, Timothy W. Secomb - Nature reviews. Cancer 2017 cited by 734
- Thresholds for thermal damage to normal tissues: An update
Authors: Pavel Yarmolenko, Eui Jung Moon, Chelsea D. Landon, Ashley A. Manzoor, Daryl W. Hochman, Benjamin L. Viglianti, Mark W. Dewhirst - International Journal of Hyperthermia 2011 cited by 727
- Basic principles of thermal dosimetry and thermal thresholds for tissue damage from hyperthermia
Authors: Mark W. Dewhirst, Benjamin L. Viglianti, Michaël Lora‐Michiels, Mark A. Hanson, P. Jack Hoopes - International Journal of Hyperthermia 2003 cited by 992
- Elevated tumor lactate concentrations predict for an increased risk of metastases in head-and-neck cancer
Authors: David M. Brizel, Thies Schroeder, Richard L. Scher, Stefan Walenta, Robert Clough, Mark W. Dewhirst, Wolfgang Mueller‐Klieser - International Journal of Radiation Oncology*Biology*Physics 2001 cited by 578
- Targeting the Lactate Transporter MCT1 in Endothelial Cells Inhibits Lactate-Induced HIF-1 Activation and Tumor Angiogenesis
Authors: Pierre Sonveaux, Tamara Copetti, Christophe J. De Saedeleer, Frédérique Végran, Julien Verrax, Kelly M. Kennedy, Eui Jung Moon, Suveera Dhup, Pierre Danhier, Françoise Frérart, Bernard Gallez, Anthony A. Ribeiro, Carine Michiels, Mark W. Dewhirst, Olivier Féron - PLoS ONE 2012 cited by 530
- Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response
Authors: Mark W. Dewhirst, Yiting Cao, Benjamin J. Moeller - Nature reviews. Cancer 2008 cited by 1,012
- Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors
Authors: Benjamin J. Moeller, Yiting Cao, Chuan Y. Li, Mark W. Dewhirst - Cancer Cell 2004 cited by 978
- Modulation of Murine Breast Tumor Vascularity, Hypoxia, and Chemotherapeutic Response by Exercise
Authors: Allison Betof Warner, Christopher D. Lascola, Douglas H. Weitzel, Chelsea D. Landon, Peter M. Scarbrough, Gayathri R. Devi, Gregory M. Palmer, Lee W. Jones, Mark W. Dewhirst - JNCI Journal of the National Cancer Institute 2015 cited by 307
- Tumor Vascular Permeability, Accumulation, and Penetration of Macromolecular Drug Carriers
Authors: Matthew R. Dreher, Wenge Liu, Charles R. Michelich, Mark W. Dewhirst, Fan Yuan, Ashutosh Chilkoti - JNCI Journal of the National Cancer Institute 2006 cited by 923
- A dual-emissive-materials design concept enables tumour hypoxia imaging
Authors: Guoqing Zhang, Gregory M. Palmer, Mark W. Dewhirst, Cassandra L. Fraser - Nature Materials 2009 cited by 1,144
- Overcoming Limitations in Nanoparticle Drug Delivery: Triggered, Intravascular Release to Improve Drug Penetration into Tumors
Authors: Ashley A. Manzoor, Lars H. Lindner, Chelsea D. Landon, Ji Young Park, Andrew J. Simnick, Matthew R. Dreher, Shiva K. Das, Gabi Hanna, Won Park, Ashutosh Chilkoti, Gerben A. Koning, Timo L.M. ten Hagen, David Needham, Mark W. Dewhirst - Cancer Research 2012 cited by 455
- CEM43°C thermal dose thresholds: a potential guide for magnetic resonance radiofrequency exposure levels?
Authors: Gerard C. van Rhoon, Theodoros Samaras, Pavel Yarmolenko, Mark W. Dewhirst, Esra Neufeld, Niels Kuster - European Radiology 2013 cited by 330
- IL-6 trans-signaling licenses mouse and human tumor microvascular gateways for trafficking of cytotoxic T cells
Authors: Daniel T. Fisher, Qing Chen, Joseph J. Skitzki, Jason B. Muhitch, Lei Zhou, Michelle M. Appenheimer, Trupti D. Vardam, Emily Weis, Jessica Passanese, Wan‐Chao Wang, Sandra O. Gollnick, Mark W. Dewhirst, Stefan Rose‐John, Elizabeth A. Repasky, Heinz Baumann, Sharon S. Evans - Journal of Clinical Investigation 2011 cited by 227
- Temperature Matters! And Why It Should Matter to Tumor Immunologists
Authors: Elizabeth A. Repasky, Sharon S. Evans, Mark W. Dewhirst - Cancer Immunology Research 2013 cited by 243
- Efficacy and Mechanisms of Aerobic Exercise on Cancer Initiation, Progression, and Metastasis: A Critical Systematic Review of In Vivo Preclinical Data
Authors: Kathleen A. Ashcraft, Ralph M. Peace, Allison Betof Warner, Mark W. Dewhirst, Lee W. Jones - Cancer Research 2016 cited by 209
- ERRα-Regulated Lactate Metabolism Contributes to Resistance to Targeted Therapies in Breast Cancer
Authors: Sung Hee Park, Ching‐yi Chang, Rachid Safi, Xiaojing Liu, Robert Baldi, Jeff S. Jasper, Grace R. Anderson, Tingyu Liu, Jeffrey C. Rathmell, Mark W. Dewhirst, Kris C. Wood, Jason W. Locasale, Donald P. McDonnell - Cell Reports 2016 cited by 141
- Tumor Metabolism of Lactate: The Influence and Therapeutic Potential for MCT and CD147 Regulation
Authors: Kelly M. Kennedy, Mark W. Dewhirst - Future Oncology 2009 cited by 277
- Randomized Trial of Hyperthermia and Radiation for Superficial Tumors
Authors: Ellen L. Jones, James R. Oleson, Leonard R. Prosnitz, Thaddeus V. Samulski, Željko Vujašković, Daohai Yu, Linda Sanders, Mark W. Dewhirst - Journal of Clinical Oncology 2005 cited by 562
- Catabolism of Exogenous Lactate Reveals It as a Legitimate Metabolic Substrate in Breast Cancer
Authors: Kelly M. Kennedy, Peter M. Scarbrough, Anthony A. Ribeiro, Rachel A. Richardson, Hong Yuan, Pierre Sonveaux, Chelsea D. Landon, Jen‐Tsan Chi, Salvatore V. Pizzo, Thies Schroeder, Mark W. Dewhirst - PLoS ONE 2013 cited by 187
- Green's Function Methods for Analysis of Oxygen Delivery to Tissue by Microvascular Networks
Authors: Timothy W. Secomb, Richard Hsu, Eric Park, Mark W. Dewhirst - Annals of Biomedical Engineering 2004 cited by 247
- Exercise as Adjunct Therapy in Cancer
Authors: Kathleen A. Ashcraft, Allison Betof Warner, Lee W. Jones, Mark W. Dewhirst - Seminars in Radiation Oncology 2018 cited by 140
- Cyclic Hypoxia: An Update on Its Characteristics, Methods to Measure It and Biological Implications in Cancer
Authors: Samuel B. Bader, Mark W. Dewhirst, Ester M. Hammond - Cancers 2020 cited by 122
