litlas
Log inCreate account

Markus Schirle

Active 1998–2025

60
Papers
18,328
Citations
48
h-index
57
i10-index

Citations

Citations per year for Markus Schirle1932: 1 citations1973: 1 citations1983: 1 citations1984: 1 citations1991: 1 citations1995: 1 citations1998: 2 citations1999: 27 citations2000: 34 citations2001: 37 citations2002: 64 citations2003: 46 citations2004: 86 citations2005: 106 citations2006: 144 citations2007: 212 citations2008: 252 citations2009: 259 citations2010: 266 citations2011: 254 citations2012: 332 citations2013: 259 citations2014: 195 citations2015: 253 citations2016: 229 citations2017: 210 citations2018: 188 citations2019: 522 citations2020: 515 citations2021: 645 citations2022: 569 citations2023: 517 citations2024: 784 citations2025: 488 citations2026: 17 citations1933–1972: no citations, so these years are not shown1974–1982: no citations, so these years are not shown1985–1990: no citations, so these years are not shown1992–1994: no citations, so these years are not shown1996–1997: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 2,595 citing papers, 27.4% of this breakdownChina: 1,310 citing papers, 13.8% of this breakdownGermany: 845 citing papers, 8.9% of this breakdownUnited Kingdom: 664 citing papers, 7% of this breakdownCanada: 362 citing papers, 3.8% of this breakdownSwitzerland: 326 citing papers, 3.5% of this breakdownJapan: 272 citing papers, 2.9% of this breakdownFrance: 243 citing papers, 2.6% of this breakdownItaly: 231 citing papers, 2.4% of this breakdownNetherlands: 202 citing papers, 2.1% of this breakdownIndia: 184 citing papers, 2% of this breakdownSpain: 159 citing papers, 1.7% of this breakdown
0%27.4%Other 21.9%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology57.7%
  • Medicine20.2%
  • Chemistry9.5%
  • Immunology and Microbiology6%
  • Computer Science1.8%
  • Neuroscience1.1%
  • Other3.7%

Topics

  • Ubiquitin and proteasome pathways6.2%
  • Protein Degradation and Inhibitors5.2%
  • Bioinformatics and Genomic Networks4.6%
  • Advanced Proteomics Techniques and Applications3.4%
  • Wnt/β-catenin signaling in development and cancer2.5%
  • Peptidase Inhibition and Analysis2.4%
  • Other75.7%

Coauthors

All papers

Open in search
  1. Structure of the DDB1–CRBN E3 ubiquitin ligase in complex with thalidomide

    Authors: Eric S. Fischer, Kerstin Böhm, John R. Lydeard, Haidi Yang, Michael Stadler, Simone Cavadini, Jane Nagel, Fabrizio C. Serluca, Vincent Acker, Gondichatnahalli M. Lingaraju, Ritesh B. Tichkule, Michael Schebesta, William C. Forrester, Markus Schirle, Ulrich Hassiepen, Johannes Ottl, Marc Hild, Rohan E. J. Beckwith, J. Wade Harper, Jeremy L. Jenkins, Nicolas H. Thomä - Nature 2014 cited by 1,115

  2. Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo

    Authors: William E. Dowdle, Beat Nyfeler, Jane Nagel, R.A. Elling, Shanming Liu, Ellen Triantafellow, Suchithra Menon, Zuncai Wang, Ayako Honda, Gwynn Pardee, John Cantwell, Catherine A. Luu, Iván Cornella‐Taracido, Edmund Harrington, Peter Fekkes, Hong Lei, Qing Fang, Mary Ellen Digan, Debra Burdick, Andrew F. Powers, Stephen B. Helliwell, Simon d‘Aquin, Julie Bastien, Henry Wang, Dmitri Wiederschain, Jenny Kuerth, Philip J. Bergman, David J. Schwalb, Jason R. Thomas, Savuth Ugwonali, Fred Harbinski, John A. Tallarico, Christopher J. Wilson, Vic E. Myer, Jeffery A. Porter, Dirksen E. Bussiere, Peter M. Finan, Mark Labow, Xiaohong Mao, Lawrence G. Hamann, Brendan D. Manning, Reginald Valdez, Thomas Nicholson, Markus Schirle, Mark Knapp, Erin P. Keaney, Leon O. Murphy - Nature Cell Biology 2014 cited by 740

  3. Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

    Authors: Shih-Min A. Huang, Yuji Mishina, Shanming Liu, Atwood K. Cheung, Frank Stegmeier, Gregory A. Michaud, Olga Charlat, Elizabeth L. Wiellette, Yue Zhang, Stephanie Wiessner, Marc Hild, Xiaoying Shi, Christopher J. Wilson, Craig Mickanin, Vic E. Myer, Aleem Fazal, Ronald Tomlinson, Fabrizio C. Serluca, Wenlin Shao, Hong Cheng, Michael D. Shultz, Christina Rau, Markus Schirle, Judith Schlegl, Sonja Ghidelli, Stephen E. Fawell, Chuang Lu, Daniel Curtis, Marc W. Kirschner, Christoph Lengauer, Peter M. Finan, John A. Tallarico, Tewis Bouwmeester, Jeffery A. Porter, Andreas Bauer, Feng Cong - Nature 2009 cited by 2,099

  4. Deubiquitinase-targeting chimeras for targeted protein stabilization

    Authors: Nathaniel J. Henning, Lydia Boike, Jessica N. Spradlin, Carl C. Ward, Gang Liu, Erika Zhang, Bridget P. Belcher, Scott M. Brittain, Matthew J. Hesse, Dustin Dovala, Lynn M. McGregor, Rachel Valdez Misiolek, Lindsey W. Plasschaert, David J. Rowlands, Feng Wang, Andreas O. Frank, Daniel Fuller, Abigail R. Estes, Katelyn L. Randal, Anoohya Panidapu, Jeffrey M. McKenna, John A. Tallarico, Markus Schirle, Daniel K. Nomura - Nature Chemical Biology 2022 cited by 321

  5. Rational Chemical Design of Molecular Glue Degraders

    Authors: Ethan S. Toriki, James W. Papatzimas, Kaila Nishikawa, Dustin Dovala, Andreas O. Frank, Matthew J. Hesse, Daniela Danková, Jae-Geun Song, Megan Bruce-Smythe, Heidi Struble, F. García, Scott M. Brittain, Andrew C. Kile, Lynn M. McGregor, Jeffrey M. McKenna, John A. Tallarico, Markus Schirle, Daniel K. Nomura - ACS Central Science 2023 cited by 183

  6. Harnessing the anti-cancer natural product nimbolide for targeted protein degradation

    Authors: Jessica N. Spradlin, Xirui Hu, Carl C. Ward, Scott M. Brittain, Michael D. Jones, Lisha Ou, Milton To, Andrew Proudfoot, Elizabeth Ornelas, Mikias Woldegiorgis, James A. Olzmann, Dirksen E. Bussiere, Jason R. Thomas, John A. Tallarico, Jeffrey M. McKenna, Markus Schirle, Thomas J. Maimone, Daniel K. Nomura - Nature Chemical Biology 2019 cited by 424

  7. Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications

    Authors: Carl C. Ward, Jordan I. Kleinman, Scott M. Brittain, Patrick S. Lee, Clive Yik‐Sham Chung, Kenneth H. Kim, Yana Petri, Jason R. Thomas, John A. Tallarico, Jeffrey M. McKenna, Markus Schirle, Daniel K. Nomura - ACS Chemical Biology 2019 cited by 336

  8. Discovery of a Covalent FEM1B Recruiter for Targeted Protein Degradation Applications

    Authors: Nathaniel J. Henning, Andrew G. Manford, Jessica N. Spradlin, Scott M. Brittain, Erika Zhang, Jeffrey M. McKenna, John A. Tallarico, Markus Schirle, Michael Rapé, Daniel K. Nomura - Journal of the American Chemical Society 2022 cited by 211

  9. Chemoproteomics-enabled discovery of covalent RNF114-based degraders that mimic natural product function

    Authors: Mai Luo, Jessica N. Spradlin, Lydia Boike, Bingqi Tong, Scott M. Brittain, Jeffrey M. McKenna, John A. Tallarico, Markus Schirle, Thomas J. Maimone, Daniel K. Nomura - Cell chemical biology 2021 cited by 186

  10. Chemoproteomics-enabled discovery of a covalent molecular glue degrader targeting NF-κB

    Authors: Elizabeth A. King, Yoo Jin Cho, Nathan S. Hsu, Dustin Dovala, Jeffrey M. McKenna, John A. Tallarico, Markus Schirle, Daniel K. Nomura - Cell chemical biology 2023 cited by 99

  11. DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance

    Authors: Martin Schröder, Martin Renatus, Xiaoyou Liang, Fabian Meili, Thomas Zöller, Sandrine Ferrand, François Gauter, Xiaoyan Li, Frederic Sigoillot, Scott Gleim, Therese‐Marie Stachyra, Jason R. Thomas, Damien Bégué, Maryam Khoshouei, Peggy Lefeuvre, Rita Andraos-Rey, BoYee Chung, Renate Ma, Benika J. Pinch, Andreas Hofmann, Markus Schirle, Niko Schmiedeberg, Patricia Imbach, Delphine Gorses, Keith Calkins, Beatrice Bauer-Probst, Magdalena Maschlej, Matt Niederst, Rob Maher, Martin Hénault, John Alford, Erik Ahrné, Luca Tordella, Greg Hollingworth, Nicolas H. Thomä, Anna Vulpetti, Thomas Radimerski, Philipp Holzer, Seth Carbonneau, Claudio R. Thoma - Nature Communications 2024 cited by 88

  12. Discovery of a Functional Covalent Ligand Targeting an Intrinsically Disordered Cysteine within MYC

    Authors: Lydia Boike, Alexander G. Cioffi, Felix C. Majewski, Jennifer Co, Nathaniel J. Henning, Michael D. Jones, Gang Liu, Jeffrey M. McKenna, John A. Tallarico, Markus Schirle, Daniel K. Nomura - Cell chemical biology 2020 cited by 158

  13. Proteome survey reveals modularity of the yeast cell machinery

    Authors: Anne‐Claude Gavin, Patrick Aloy, Paola Grandi, Roland Krause, Markus Böesche, Martina Marzioch, Christina Rau, Lars Juhl Jensen, Sonja Bastuck, Birgit Dümpelfeld, Angela Edelmann, Marie-Anne Heurtier, Verena Hoffman, Christian Hoefert, Karin Klein, Manuela Hudak, Anne‐Marie Michon, Malgorzata Schelder, Markus Schirle, Marita Remor, Tatjana Rudi, Sean Hooper, Andreas Bauer, Tewis Bouwmeester, Georg Casari, Gerard Drewes, Gitte Neubauer, Jens M. Rick, Bernhard Küster, Peer Bork, Robert B. Russell, Giulio Superti‐Furga - Nature 2006 cited by 2,591

  14. RNF146 is a poly(ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling

    Authors: Yue Zhang, Shanming Liu, Craig Mickanin, Feng Yan, Olga Charlat, Gregory A. Michaud, Markus Schirle, Xiaoying Shi, Marc Hild, Andreas Bauer, Vic E. Myer, Peter M. Finan, Jeffery A. Porter, Shih-Min A. Huang, Feng Cong - Nature Cell Biology 2011 cited by 434

  15. Manumycin polyketides act as molecular glues between UBR7 and P53

    Authors: Yosuke Isobe, Mikiko Okumura, Lynn M. McGregor, Scott M. Brittain, Michael D. Jones, Xiaoyou Liang, R. Larry White, William C. Forrester, Jeffrey M. McKenna, John A. Tallarico, Markus Schirle, Thomas J. Maimone, Daniel K. Nomura - Nature Chemical Biology 2020 cited by 134

  16. Activation of human STING by a molecular glue-like compound

    Authors: Jie Li, Stephen M. Canham, Hua Wu, Martin Hénault, Lihao Chen, Guoxun Liu, Yu Chen, Gary Yu, Howard Miller, Viktor Horn̆ák, Scott M. Brittain, Gregory A. Michaud, Antonin Tutter, Wendy Broom, Mary Ellen Digan, Sarah M. McWhirter, Kelsey E. Sivick, Helen Trinh Pham, Christine Chen, George S. Tria, Jeffery M. McKenna, Markus Schirle, Xiaohong Mao, Thomas B. Nicholson, Yuan Wang, Jeremy L. Jenkins, Rishi K. Jain, John A. Tallarico, Sejal Patel, Lianxing Zheng, Nathan T. Ross, Charles Y. Cho, Xuewu Zhang, Xiao‐chen Bai, Yan Feng - Nature Chemical Biology 2023 cited by 71

  17. Bardoxolone conjugation enables targeted protein degradation of BRD4

    Authors: Bingqi Tong, Mai Luo, Yi Xie, Jessica N. Spradlin, John A. Tallarico, Jeffrey M. McKenna, Markus Schirle, Thomas J. Maimone, Daniel K. Nomura - Scientific Reports 2020 cited by 139

  18. Targeted Protein Degradation through E2 Recruitment

    Authors: Nafsika Forte, Dustin Dovala, Matthew J. Hesse, Jeffrey M. McKenna, John A. Tallarico, Markus Schirle, Daniel K. Nomura - ACS Chemical Biology 2023 cited by 55

  19. Quantitative mass spectrometry in proteomics: a critical review

    Authors: Marcus Bantscheff, Markus Schirle, Gavain M.A. Sweetman, Jens M. Rick, Bernhard Küster - Analytical and Bioanalytical Chemistry 2007 cited by 1,661

  20. A physical and functional map of the human TNF-α/NF-κB signal transduction pathway

    Authors: Tewis Bouwmeester, Angela Bauch, Heinz Ruffner, Pierre‐Olivier Angrand, Giovanna Bergamini, Karen Croughton, Cristina-Maria Cruciat, Dirk Eberhard, Julien Gagneur, Sonja Ghidelli, Carsten Hopf, Bettina Huhse, Raffaella Mangano, Anne‐Marie Michon, Markus Schirle, Judith Schlegl, Markus S. Schwab, Martin Stein, Andreas Bauer, Georg Casari, Gerard Drewes, Anne‐Claude Gavin, David Jackson, Gérard Joberty, Gitte Neubauer, Jens M. Rick, Bernhard Küster, Giulio Superti‐Furga - Nature Cell Biology 2004 cited by 1,028

  21. Dermcidin: a novel human antibiotic peptide secreted by sweat glands

    Authors: Birgit Schittek, Rainer Hipfel, Birgit Sauer, Jürgen Bauer, Hubert Kalbacher, Stefan Stevanović, Markus Schirle, Kristina Schroeder, Nikolaus Blin, Friedegund Meier, G. Rassner, Claus Garbe - Nature Immunology 2001 cited by 735

  22. Natural products reveal cancer cell dependence on oxysterol-binding proteins

    Authors: Anthony W. G. Burgett, Thomas B. Poulsen, Kittikhun Wangkanont, D. Ryan Anderson, Chikako Kikuchi, Kousei Shimada, Shuichi Okubo, Kevin C. Fortner, Yoshihiro Mimaki, Minpei Kuroda, Jason Murphy, David J. Schwalb, Eugene C. Petrella, Iván Cornella‐Taracido, Markus Schirle, John A. Tallarico, Matthew D. Shair - Nature Chemical Biology 2011 cited by 261

  23. A Nimbolide-Based Kinase Degrader Preferentially Degrades Oncogenic BCR-ABL

    Authors: Bingqi Tong, Jessica N. Spradlin, Luiz F. T. Novaes, Erika Zhang, Xirui Hu, Malte Moeller, Scott M. Brittain, Lynn M. McGregor, Jeffrey M. McKenna, John A. Tallarico, Markus Schirle, Thomas J. Maimone, Daniel K. Nomura - ACS Chemical Biology 2020 cited by 110

  24. Donor–Acceptor Pyridinium Salts for Photo-Induced Electron-Transfer-Driven Modification of Tryptophan in Peptides, Proteins, and Proteomes Using Visible Light

    Authors: Caleb Hoopes, Francisco J. Garcia, Akash Mamon Sarkar, Nicholas Kuehl, David T. Barkan, Nicole Collins, Glenna E. Meister, Taylor R. Bramhall, Chien-Hsiang Hsu, Michael D. Jones, Markus Schirle, Michael T. Taylor - Journal of the American Chemical Society 2022 cited by 69