Michael D. Waterfield
Active 1975–2008
- 100
- Papers
- 43,108
- Citations
- 93
- h-index
- 100
- i10-index
Citations
Citation sources
Countries
Institutions
- Harvard University1.9%
- Howard Hughes Medical Institute1.6%
- National Institutes of Health1.1%
- University College London1.1%
- Inserm0.9%
- National Cancer Institute0.9%
- Other92.5%
Fields
- Biochemistry, Genetics and Molecular Biology51.2%
- Medicine33.7%
- Immunology and Microbiology5.8%
- Neuroscience5.7%
- Chemistry1.4%
- Agricultural and Biological Sciences0.7%
- Other1.5%
Topics
- Protein Kinase Regulation and GTPase Signaling5.3%
- PI3K/AKT/mTOR signaling in cancer4.8%
- Cellular transport and secretion3.3%
- HER2/EGFR in Cancer Research2.9%
- Monoclonal and Polyclonal Antibodies Research2.7%
- Cell Adhesion Molecules Research1.8%
- Other79.2%
Coauthors
- Ivan Gout17
- George Panayotou14
- Bart Vanhaesebroeck13
- Marketa Zvelebil13
- Peter J. Parker11
- Ritu Dhand10
- Julian Downward9
- Michael Fry9
- Paul Stroobant9
- Stefano Volinia7
- Axel Ullrich6
- J. Justin Hsuan6
- Jan Domin6
- Nigel Whittle6
- Robert C. Stein6
- Alexandre Arcaro5
- I. Hiles5
- J.J. Skehel5
- John F. Timms5
- Joseph Schlessinger5
- Nicholas F. Totty5
- Sally J. Leevers5
- William J. Gullick5
- Hiroyuki Kaizawa4
All papers
- Cellular Function of Phosphoinositide 3-Kinases: Implications for Development, Immunity, Homeostasis, and Cancer
Authors: Roy Katso, Klaus Okkenhaug, Khatereh Ahmadi, S. L. White, John F. Timms, Michael D. Waterfield - Annual Review of Cell and Developmental Biology 2001 cited by 1,195
- Phosphatidylinositol-3-OH kinase direct target of Ras
Authors: Pablo Rodriguez‐Viciana, Patricia H. Warne, Ritu Dhand, Bart Vanhaesebroeck, Ivan Gout, Michael Fry, Michael D. Waterfield, Julian Downward - Nature 1994 cited by 1,940
- A selective PIKfyve inhibitor blocks PtdIns(3,5)P2 production and disrupts endomembrane transport and retroviral budding
Authors: Harold B.J. Jefferies, Frank T. Cooke, Parmjit Jat, Christine Boucheron, Tomonobu Koizumi, Masahiko Hayakawa, Hiroyuki Kaizawa, Takahide Ohishi, Paul Workman, Michael D. Waterfield, Peter J. Parker - EMBO Reports 2008 cited by 302
- Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells
Authors: A Ullrich, Lisa M. Coussens, Joel S. Hayflick, Thomas J. Dull, Andrew Gray, Albert W. Tam, J. Lee, Yosef Yarden, Towia A. Libermann, Joseph Schlessinger, Julian Downward, E. L. V. Mayes, Nigel Whittle, Michael D. Waterfield, P. H. Seeburg - Nature 1984 cited by 2,778
- Synthesis and Function of 3-Phosphorylated Inositol Lipids
Authors: Bart Vanhaesebroeck, Sally J. Leevers, Khatereh Ahmadi, John F. Timms, Roy Katso, Paul C. Driscoll, Rüdiger Woscholski, Peter J. Parker, Michael D. Waterfield - Annual Review of Biochemistry 2001 cited by 1,511
- Exploring the specificity of the PI3K family inhibitor LY294002
Authors: Severine Gharbi, Marketa Zvelebil, Stephen J. Shuttleworth, Tim Hancox, Nahid Saghir, John F. Timms, Michael D. Waterfield - Biochemical Journal 2007 cited by 464
- Sequence and Expression of Human Estrogen Receptor Complementary DNA
Authors: Geoffrey L. Greene, Paul Gilna, Michael D. Waterfield, Andrew Baker, Yvonne Hort, John Shine - Science 1986 cited by 1,311
- Impaired B and T Cell Antigen Receptor Signaling in p110δ PI 3-Kinase Mutant Mice
Authors: Klaus Okkenhaug, Antonio Bilancio, Géraldine Farjot, Helen Priddle, Sara Sancho, Emma Peskett, Wayne Pearce, Stephen Meek, Ashreena Salpekar, Michael D. Waterfield, Andrew J. H. Smith, Bart Vanhaesebroeck - Science 2002 cited by 940
- Phosphatidylinositol-3-OH kinases are Rab5 effectors
Authors: Savvas Christoforidis, Marta Miączyńska, Keith Ashman, Matthias Wilm, Liyun Zhao, Shu-Chin Yip, Michael D. Waterfield, Jonathan Backer, Marino Zerial - Nature Cell Biology 1999 cited by 627
- Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences
Authors: Julian Downward, Yosef Yarden, E. L. V. Mayes, Geoffrey Scrace, Nicholas F. Totty, Peter A. Stockwell, A. Ullrich, Joseph Schlessinger, Michael D. Waterfield - Nature 1984 cited by 2,536
- Phosphatidylinositol 3-Kinase Encoded by Yeast VPS 34 Gene Essential for Protein Sorting
Authors: Peter Schu, Kaoru Takegawa, Michael Fry, Jeffrey H. Stack, Michael D. Waterfield, Scott D. Emr - Science 1993 cited by 923
- Signaling by Distinct Classes of Phosphoinositide 3-Kinases
Authors: Bart Vanhaesebroeck, Michael D. Waterfield - Experimental Cell Research 1999 cited by 854
- Changes in the conformation of influenza virus hemagglutinin at the pH optimum of virus-mediated membrane fusion.
Authors: J.J. Skehel, Peter M. Bayley, E.B. Brown, S.R. Martin, Michael D. Waterfield, J White, Ian A. Wilson, Don C. Wiley - National Academy of Sciences, Proceedings of the National Academy of Sciences 1982 cited by 735
- Cloning of the human estrogen receptor cDNA.
Authors: Peter Walter, Stephen Green, Geoffrey L. Greene, A. Krust, Jean‐Marc Bornert, Jean‐Marc Jeltsch, Adrien Staub, Erik Ø. Jensen, Geoffrey Scrace, Michael D. Waterfield - National Academy of Sciences, Proceedings of the National Academy of Sciences 1985 cited by 725
- A human phosphatidylinositol 3‐kinase complex related to the yeast Vps34p‐Vps15p protein sorting system.
Authors: Stefano Volinia, Ritu Dhand, Bart Vanhaesebroeck, Lindsay K. MacDougall, Robert C. Stein, Marketa Zvelebil, J. Domin, Christina Panaretou, Michael D. Waterfield - The EMBO Journal 1995 cited by 360
- Autophosphorylation sites on the epidermal growth factor receptor
Authors: Julian Downward, Peter J. Parker, Michael D. Waterfield - Nature 1984 cited by 722
- Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin
Authors: Towia A. Libermann, Harris R. Nusbaum, Nissim Razon, Richard Kris, Irit Lax, Hermona Soreq, Nigel Whittle, Michael D. Waterfield, Axel Ullrich, Joseph Schlessinger - Nature 1985 cited by 1,518
- Phosphoinositide 3-kinases: A conserved family of signal transducers
Authors: Bart Vanhaesebroeck, Sally J. Leevers, George Panayotou, Michael D. Waterfield - Trends in Biochemical Sciences 1997 cited by 947
- Signalling through phosphoinositide 3-kinases: the lipids take centre stage
Authors: Sally J. Leevers, Bart Vanhaesebroeck, Michael D. Waterfield - Current Opinion in Cell Biology 1999 cited by 681
- Synthesis and biological evaluation of pyrido[3′,2′:4,5]furo[3,2-d]pyrimidine derivatives as novel PI3 kinase p110α inhibitors
Authors: Masahiko Hayakawa, Hiroyuki Kaizawa, Hiroyuki Moritomo, Tomonobu Koizumi, Takahide Ohishi, Mayumi Yamano, Minoru Okada, Mitsuaki Ohta, Shin‐ichi Tsukamoto, Florence I. Raynaud, Paul Workman, Michael D. Waterfield, Peter J. Parker - Bioorganic & Medicinal Chemistry Letters 2007 cited by 141
- Role of Phosphoinositide 3-OH Kinase in Cell Transformation and Control of the Actin Cytoskeleton by Ras
Authors: Pablo Rodriguez‐Viciana, Patricia H. Warne, Asim Khwaja, Barbara Marte, Darryl Pappin, Pamela Das, Michael D. Waterfield, Anne J. Ridley, Julian Downward - Cell 1997 cited by 1,070
- Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system
Authors: Mark A. Marchionni, Andrew Goodearl, Maio S. Chen, Olivia Bermingham‐McDonogh, Cassandra Kirk, Marvin Hendricks, Frank Danehy, Don J Misumi, Judith Sudhalter, Kazumi Kobayashi, Diana Wroblewski, Catherine Lynch, Mark Baldassare, Ian D. Hiles, John B. Davis, J. Justin Hsuan, Nicholas F. Totty, Masayuki Otsu, Robert McBurney, Michael D. Waterfield, Paul Stroobant, David I. Gwynne - Nature 1993 cited by 742
- Wortmannin Inactivates Phosphoinositide 3-Kinase by Covalent Modification of Lys-802, a Residue Involved in the Phosphate Transfer Reaction
Authors: Matthias P. Wymann, Ginette Bulgarelli-Leva, Marketa Zvelebil, Luciano Pirola, Bart Vanhaesebroeck, Michael D. Waterfield, George Panayotou - Molecular and Cellular Biology 1996 cited by 680
- p110δ, a novel phosphoinositide 3-kinase in leukocytes
Authors: Bart Vanhaesebroeck, Melanie J. Welham, Kei Kotani, Robert C. Stein, Patricia H. Warne, Marketa Zvelebil, Kyoichiro Higashi, Stefano Volinia, Julian Downward, Michael D. Waterfield - National Academy of Sciences, Proceedings of the National Academy of Sciences 1997 cited by 431
