Michael J. Lenardo
Active 1987–2025
- Also published as
- Michael J Lenardo
- 164
- Papers
- 52,111
- Citations
- 110
- h-index
- 160
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology34.3%
- Medicine33.5%
- Immunology and Microbiology24.5%
- Neuroscience2.1%
- Engineering1.2%
- Nursing1.1%
- Other3.3%
Topics
- Immune Cell Function and Interaction5.7%
- T-cell and B-cell Immunology4%
- Cell death mechanisms and regulation3.8%
- NF-κB Signaling Pathways3.6%
- Immunotherapy and Immune Responses3.4%
- Autophagy in Disease and Therapy3.3%
- Other76.2%
Coauthors
- Lixin Zheng46
- Helen C. Su19
- Richard M. Siegel18
- Stephen E. Straus17
- Helen Matthews16
- Jennifer M. Puck15
- Yu Zhang14
- Francis Ka-Ming Chan13
- Janet K. Dale13
- Thomas A. Fleisher12
- Ahmet Özen10
- Jin Wang10
- Elif Karakoç-Aydıner9
- Fengyi Wan9
- Gülbû Uzel9
- Nicolas Bidère9
- V. Koneti Rao9
- David Baltimore8
- Jeffrey I. Cohen8
- Ping Jiang8
- Susan Price8
- Yikun Yao8
- Juan C. Ravell7
- Li Yu7
All papers
- A guide to cancer immunotherapy: from T cell basic science to clinical practice
Authors: Alex D. Waldman, Jill M. Fritz, Michael J. Lenardo - Nature reviews. Immunology 2020 cited by 4,146
- 30 Years of NF-κB: A Blossoming of Relevance to Human Pathobiology
Authors: Qian Zhang, Michael J. Lenardo, David Baltimore - Cell 2017 cited by 2,072
- Mucus sialylation determines intestinal host-commensal homeostasis
Authors: Yikun Yao, Girak Kim, Samantha Shafer, Zuojia Chen, Satoshi Kubo, Yanlong Ji, Jialie Luo, Weiming Yang, Sebastian P. Perner, Chrysi Kanellopoulou, Ann Y. Park, Ping Jiang, Jian Li, Safa Barış, Elif Karakoç-Aydıner, Deniz Ertem, Daniel J. Mulder, Neil Warner, Anne M. Griffiths, Chani Topf‐Olivestone, Michal Kori, Lael Werner, Jodie Ouahed, Michael Field, Chengyu Liu, Benjamin Schwarz, Catharine M. Bosio, Sundar Ganesan, Jian Song, Henning Urlaub, Thomas Oellerich, Stacy A. Malaker, Lixin Zheng, Carolyn R. Bertozzi, Yu Zhang, Helen Matthews, Will Montgomery, Han‐Yu Shih, Jiansheng Jiang, Marcus B. Jones, Aris Baras, Alan R. Shuldiner, Claudia Gonzaga‐Jauregui, Scott B. Snapper, Aleixo M. Muise, Dror S. Shouval, Ahmet Özen, Kuan‐Ting Pan, Chuan Wu, Michael J. Lenardo - Cell 2022 cited by 243
- Termination of autophagy and reformation of lysosomes regulated by mTOR
Authors: Li Yu, Christina McPhee, Lixin Zheng, Gonzalo A. Mardones, Yueguang Rong, Junya Peng, Na Mi, Ying Zhao, Zhihua Liu, Fengyi Wan, Dale W. Hailey, Viola Oorschot, Judith Klumperman, Eric H. Baehrecke, Michael J. Lenardo - Nature 2010 cited by 1,574
- Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease
Authors: Najoua Lalaoui, Steven E. Boyden, Hirotsugu Oda, Geryl Wood, Deborah L. Stone, Diep Chau, Lin Liu, Monique Stoffels, Tobias Kratina, Kate E. Lawlor, Kristien J.M. Zaal, Patrycja Hoffmann, Nima Etemadi, Kristy Shield‐Artin, Christine Biben, Wanxia Li Tsai, Mary Blake, Hye Sun Kuehn, Dan Yang, Holly Anderton, Natasha Silke, Laurens Wachsmuth, Lixin Zheng, Natalia Sampaio Moura, David B. Beck, Gustavo Gutierrez-Cruz, Amanda K. Ombrello, Gineth Paola Pinto-Patarroyo, Andrew J. Kueh, Marco J. Herold, Cathrine Hall, Hongying Wang, Jae Jin Chae, Natalia I. Dmitrieva, Mark McKenzie, Amanda Light, Beverly Barham, Anne Jones, Tina Romeo, Qing Zhou, Ivona Aksentijevich, James C. Mullikin, Andrew J. Gross, Anthony K. Shum, Edwin D. Hawkins, Seth L. Masters, Michael J. Lenardo, Manfred Boehm, Sergio D. Rosenzweig, Manolis Pasparakis, Anne K. Voss, Massimo Gadina, Daniel L. Kastner, John Silke - Nature 2019 cited by 333
- The TNF and TNF Receptor Superfamilies
Authors: Richard M. Locksley, Nigel Killeen, Michael J. Lenardo - Cell 2001 cited by 3,616
- Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4
Authors: Hye Sun Kuehn, Weiming Ouyang, Bernice Lo, Elissa K. Deenick, Julie E. Niemela, Danielle T. Avery, Jean-Nicolas Schickel, Dat Q. Tran, Jennifer Stoddard, Yu Zhang, David M. Frucht, Bogdan Dumitriu, Phillip Scheinberg, Les Folio, Cathleen Frein, Susan Price, Christopher Koh, Theo Heller, Christine M. Seroogy, Anna Huttenlocher, V. Koneti Rao, Helen C. Su, David E. Kleiner, Luigi D. Notarangelo, Yajesh Rampertaap, Kenneth N. Olivier, Joshua McElwee, Jason D. Hughes, Stefania Pittaluga, João Bosco Oliveira, Eric Meffre, Thomas A. Fleisher, Steven M. Holland, Michael J. Lenardo, Stuart G. Tangye, Gülbû Uzel - Science 2014 cited by 855
- CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation–mediated apoptosis of effector CD4+ T cells
Authors: Pushpa Pandiyan, Lixin Zheng, Satoru Ishihara, Jennifer L. Reed, Michael J. Lenardo - Nature Immunology 2007 cited by 1,221
- A randomized, placebo-controlled phase 3 trial of the PI3Kδ inhibitor leniolisib for activated PI3Kδ syndrome
Authors: V. Koneti Rao, Sharon Webster, Anna Šedivá, Alessandro Plebani, Catharina Schuetz, Anna Shcherbina, Niall Conlon, Tanya Coulter, Virgil A. S. H. Dalm, Antonino Trizzino, Yulia Zharankova, Elaine Kulm, Julia Körholz, Vassilios Lougaris, Yulia Rodina, Kath Radford, Jason Bradt, Klaus Kucher, Anurag Relan, Steven M. Holland, Michael J. Lenardo, Gülbû Uzel - Blood 2022 cited by 132
- Patients with LRBA deficiency show CTLA4 loss and immune dysregulation responsive to abatacept therapy
Authors: Bernice Lo, Kejian Zhang, Wei Lü, Lixin Zheng, Qian Zhang, Chrysi Kanellopoulou, Yu Zhang, Zhiduo Liu, Jill M. Fritz, Rebecca Marsh, Ammar Husami, Diane Kissell, Shannon Nortman, Vijaya Chaturvedi, Hilary Haines, Lisa R. Young, Jun Mo, Alexandra H. Filipovich, Jack Bleesing, Peter Mustillo, Michael C. Stephens, Cesar M. Rueda, Claire Chougnet, Kasper Hoebe, Joshua McElwee, Jason D. Hughes, Elif Karakoç-Aydıner, Helen Matthews, Susan Price, Helen C. Su, V. Koneti Rao, Michael J. Lenardo, Michael B. Jordan - Science 2015 cited by 691
- Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110δ result in T cell senescence and human immunodeficiency
Authors: C. Lucas, Hye Sun Kuehn, Fang Zhao, Julie E. Niemela, Elissa K. Deenick, Umaimainthan Palendira, Danielle T. Avery, Leen Moens, Jennifer L. Cannons, Matthew Biancalana, Jennifer Stoddard, Weiming Ouyang, David M. Frucht, V. Koneti Rao, T. Prescott Atkinson, Anahita Agharahimi, Ashleigh A. Hussey, Les Folio, Kenneth N. Olivier, Thomas A. Fleisher, Stefania Pittaluga, Steven M. Holland, Jeffrey I. Cohen, João Bosco Oliveira, Stuart G. Tangye, Pamela L. Schwartzberg, Michael J. Lenardo, Gülbû Uzel - Nature Immunology 2013 cited by 664
- Effective “activated PI3Kδ syndrome”–targeted therapy with the PI3Kδ inhibitor leniolisib
Authors: V. Koneti Rao, Sharon Webster, Virgil A. S. H. Dalm, Anna Šedivá, P. Martin van Hagen, Steven M. Holland, Sergio D. Rosenzweig, Andreas D. Christ, Birgitte Sloth, Maciej Cabanski, Aniket Joshi, Stefan Buck, Julie Doucet, Danilo Guerini, Christoph Kalis, Ilona Pylvaenaeinen, Nicolas Soldermann, Anuj Kashyap, Gülbû Uzel, Michael J. Lenardo, Dhavalkumar D. Patel, C. Lucas, Christoph Burkhart - Blood 2017 cited by 286
- Second messenger role for Mg2+ revealed by human T-cell immunodeficiency
Authors: Feng-Yen Li, Benjamin Chaigne-Delalande, Chrysi Kanellopoulou, Jeremiah C. Davis, Helen Matthews, Daniel C. Douek, Jeffrey I. Cohen, Gülbû Uzel, Helen C. Su, Michael J. Lenardo - Nature 2011 cited by 540
- The nuclear signaling of NF-κB: current knowledge, new insights, and future perspectives
Authors: Fengyi Wan, Michael J. Lenardo - Cell Research 2009 cited by 367
- Mg 2+ Regulates Cytotoxic Functions of NK and CD8 T Cells in Chronic EBV Infection Through NKG2D
Authors: Benjamin Chaigne-Delalande, Feng-Yen Li, Geraldine M. O’Connor, Marshall J. Lukacs, Ping Jiang, Lixin Zheng, Amber N. Shatzer, Matthew Biancalana, Stefania Pittaluga, Helen Matthews, Timothy Jancel, Jack Bleesing, Rebecca Marsh, Taco W. Kuijpers, Kim E. Nichols, C. Lucas, Sunil Nagpal, Huseyin Mehmet, Helen C. Su, Jeffrey I. Cohen, Gülbû Uzel, Michael J. Lenardo - Science 2013 cited by 337
- CD55 Deficiency, Early-Onset Protein-Losing Enteropathy, and Thrombosis
Authors: Ahmet Özen, William A. Comrie, Rico Chandra Ardy, Cecilia Domínguez Conde, Buket Dalgıç, Ömer Faruk Beșer, Aaron Morawski, Elif Karakoç-Aydıner, Engin Tutar, Safa Barış, Figen Özçay, Nina K. Serwas, Yu Zhang, Helen Matthews, Stefania Pittaluga, Les Folio, Aysel Ünlüsoy Aksu, Joshua McElwee, Ana Krolo, Ayça Kıykım, Zeren Barış, Meltem Gülşan, İsmail Öğülür, Scott B. Snapper, Roderick H.J. Houwen, Helen L. Leavis, Deniz Ertem, Renate Kain, Sinan Sarı, Tülay Erkan, Helen C. Su, Kaan Boztuǧ, Michael J. Lenardo - New England Journal of Medicine 2017 cited by 199
- Autophagic programmed cell death by selective catalase degradation
Authors: Li Yu, Fengyi Wan, Sudeshna Dutta, Sarah J. Welsh, Zhihua Liu, Eric C. Freundt, Eric H. Baehrecke, Michael J. Lenardo - National Academy of Sciences, Proceedings of the National Academy of Sciences 2006 cited by 661
- A Domain in TNF Receptors That Mediates Ligand-Independent Receptor Assembly and Signaling
Authors: Francis Ka-Ming Chan, Hyung J. Chun, Lixin Zheng, Richard M. Siegel, Kimmie L. Bui, Michael J. Lenardo - Science 2000 cited by 848
- Revised diagnostic criteria and classification for the autoimmune lymphoproliferative syndrome (ALPS): report from the 2009 NIH International Workshop
Authors: João Bosco Oliveira, Jack Bleesing, Umberto Dianzani, Thomas A. Fleisher, Elaine S. Jaffe, Michael J. Lenardo, Frédéric Rieux‐Laucat, Richard M. Siegel, Helen C. Su, David T. Teachey, V. Koneti Rao - Blood 2010 cited by 486
- Mitochondrial Protein PGAM5 Regulates Mitophagic Protection against Cell Necroptosis
Authors: Wei Lü, Junhui Sun, Jeong Seon Yoon, Yan Zhang, Lixin Zheng, Elizabeth Murphy, Mark P. Mattson, Michael J. Lenardo - PLoS ONE 2016 cited by 158
- Dominant interfering fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome
Authors: Galen H. Fisher, Fredric J Rosenberg, Stephen E. Straus, Janet K. Dale, Lindsay A Middelton, Albert Y. Lin, Warren Strober, Michael J. Lenardo, Jennifer M. Puck - Cell 1995 cited by 1,471
- Heterozygous splice mutation in PIK3R1 causes human immunodeficiency with lymphoproliferation due to dominant activation of PI3K
Authors: C. Lucas, Yu Zhang, Anthony Venida, Ying Wang, Jason D. Hughes, Joshua McElwee, Morgan Butrick, Helen Matthews, Susan Price, Matthew Biancalana, Xiaochuan Wang, Michael Richards, Tamara C. Pozos, Işıl Barlan, Ahmet Özen, V. Koneti Rao, Helen C. Su, Michael J. Lenardo - The Journal of Experimental Medicine 2014 cited by 285
- Development of immune checkpoint therapy for cancer
Authors: Jill M. Fritz, Michael J. Lenardo - The Journal of Experimental Medicine 2019 cited by 179
- Genetic deficiency of the mitochondrial protein PGAM5 causes a Parkinson’s-like movement disorder
Authors: Wei Lü, Senthilkumar S. Karuppagounder, Danielle Springer, Michele D. Allen, Lixin Zheng, Brittany Chao, Yan Zhang, Valina L. Dawson, Ted M. Dawson, Michael J. Lenardo - Nature Communications 2014 cited by 175
