Mike Hutton
Active 1996–2023
- 80
- Papers
- 19,649
- Citations
- 43
- h-index
- 56
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine69.4%
- Biochemistry, Genetics and Molecular Biology15.6%
- Neuroscience6.9%
- Engineering3.8%
- Computer Science2.8%
- Immunology and Microbiology0.4%
- Other1.1%
Topics
- Alzheimer's disease research and treatments19.7%
- Amyotrophic Lateral Sclerosis Research6.4%
- Parkinson's Disease Mechanisms and Treatments4.8%
- Cholinesterase and Neurodegenerative Diseases4.4%
- Prion Diseases and Protein Misfolding3.4%
- Neuroinflammation and Neurodegeneration Mechanisms3.3%
- Other58%
Coauthors
- Matt Baker15
- Dennis W. Dickson14
- John Hardy13
- Jada Lewis11
- Eileen McGowan9
- Richard Crook8
- Shu‐Hui Yen8
- Jordi Pérez‐Tur7
- Stuart Pickering‐Brown7
- Jennifer Adamson6
- Karen Duff6
- Rosa Rademakers6
- Bradley F. Boeve5
- Henry Houlden5
- Lei He5
- Wen-Lang Lin5
- Gillian Murphy4
- Jennifer Gass4
- Karen M. Kuntz4
- Vera Knäuper4
- Boris Ratchev3
- Brendan Kelley3
- Chris Eckman3
- Debra Yager3
All papers
- Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17
Authors: Mike Hutton, Corinne Lendon, Patrizia Rizzu, Matt Baker, Susanne Froelich, Henry Houlden, Stuart Pickering‐Brown, Sumi Chakraverty, Adrian M. Isaacs, Andrew Grover, Jennifer Hackett, Jennifer Adamson, Sarah Lincoln, Dennis W. Dickson, Peter J. Davies, Ronald C. Petersen, Martijn Stevens, Esther de Graaff, Erwin Wauters, Jeltje van Baren, Marcel Hillebrand, Marijke Joosse, Jennifer M. Kwon, Petra Nowotny, Lien Kuei, Joanne Norton, John C. Morris, Lee Reed, John Q. Trojanowski, Hans Basun, Lars Lannfelt, Michael Neystat, Stanley Fahn, Francis Dark, Tony Tannenberg, Peter R. Dodd, Nick Hayward, John B. Kwok, Peter R. Schofield, Athena Andreadis, Julie S. Snowden, David Craufurd, David Neary, F. Owen, Ben A. Oostra, John Hardy, Alison Goate, John C. van Swieten, David Mann, Timothy Lynch, Peter Heutink - Nature 1998 cited by 3,540
- Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17
Authors: Matt Baker, Ian R. Mackenzie, Stuart Pickering‐Brown, Jennifer Gass, Rosa Rademakers, Caroline Lindholm, Julie S. Snowden, Jennifer Adamson, A. Dessa Sadovnick, Sara Rollinson, Ashley Cannon, Emily Dwosh, David Neary, Stacey Melquist, Anna Richardson, Dennis W. Dickson, Zdenek Berger, Jason L. Eriksen, Todd Robinson, Cynthia Zehr, Chad A. Dickey, Richard Crook, Eileen McGowan, David Mann, Bradley F. Boeve, Howard Feldman, Mike Hutton - Nature 2006 cited by 2,121
- Understanding and Mitigating Hardware Failures in Deep Learning Training Systems
Authors: Yi He, Mike Hutton, Steven Chan, Robert De Gruijl, Rama Govindaraju, Nishant Patil, Yanjing Li - Symposium on Computer Architecture, ISCA 2023 cited by 47
- Enhanced Neurofibrillary Degeneration in Transgenic Mice Expressing Mutant Tau and APP
Authors: Jada Lewis, Dennis W. Dickson, Wen-Lang Lin, Louise Chisholm, Anthony Corral, Graham L. Jones, Shu‐Hui Yen, Naruhiko Sahara, Lisa Skipper, Debra Yager, Chris Eckman, John Hardy, Mike Hutton, Eileen McGowan - Science 2001 cited by 1,602
- Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein
Authors: Jada Lewis, Eileen McGowan, Julia M. Rockwood, Heather L. Melrose, Parimala Nacharaju, Marjon van Slegtenhorst, Katrina Gwinn, Michael P. Murphy, Matt Baker, Xin Yu, Karen Duff, John Hardy, Anthony Corral, Wen-Lang Lin, Shu-Hui Yen, Dennis W. Dickson, Peter Davies, Mike Hutton - Nature Genetics 2000 cited by 1,369
- Tauopathy in Drosophila : Neurodegeneration Without Neurofibrillary Tangles
Authors: Curtis W. Wittmann, Matthew Wszolek, Joshua M. Shulman, Paul M. Salvaterra, Jada Lewis, Mike Hutton, Mel Β. Feany - Science 2001 cited by 953
- Mutations in progranulin are a major cause of ubiquitin-positive frontotemporal lobar degeneration
Authors: Jennifer Gass, Ashley Cannon, Ian R. Mackenzie, Bradley F. Boeve, Matt Baker, Jennifer Adamson, Richard Crook, Stacey Melquist, Karen M. Kuntz, Ron Petersen, Keith A. Josephs, Stuart Pickering‐Brown, Neill R. Graff‐Radford, Ryan J. Uitti, Dennis W. Dickson, Zbigniew K. Wszołek, John Gonzalez, Thomas G. Beach, Eileen H. Bigio, Nancy Johnson, Sandra Weıntraub, Marsel Mesulam, Charles L. White, Bryan K. Woodruff, Richard J. Caselli, Ging‐Yuek Robin Hsiung, Howard Feldman, Dave Knopman, Mike Hutton, Rosa Rademakers - Human Molecular Genetics 2006 cited by 578
- Increased amyloid-β42(43) in brains of mice expressing mutant presenilin 1
Authors: Karen Duff, Chris Eckman, Cindy Zehr, Xin Yu, Cristian-Mihail Prada, Jordi Pérez‐Tur, Mike Hutton, Luc Buée, Yasuo Harigaya, Debra Yager, David Morgan, Marcia N. Gordon, Leigh A. Holcomb, Lawrence M. Refolo, B. Zenk, John Hardy, Steven G. Younkin - Nature 1996 cited by 1,453
- Wild-Type Human TDP-43 Expression Causes TDP-43 Phosphorylation, Mitochondrial Aggregation, Motor Deficits, and Early Mortality in Transgenic Mice
Authors: Ya-Fei Xu, Tania F. Gendron, Yong‐Jie Zhang, Wen-Lang Lin, Simon D’Alton, Hong Sheng, Monica Castanedes Casey, Jimei Tong, Joshua A. Knight, Xin Yu, Rosa Rademakers, Khrista Boylan, Mike Hutton, Eileen McGowan, Dennis W. Dickson, Jada Lewis, Leonard Petrucelli - Journal of Neuroscience 2010 cited by 575
- Induction of Tau Pathology by Intracerebral Infusion of Amyloid-β-Containing Brain Extract and by Amyloid-β Deposition in APP × Tau Transgenic Mice
Authors: Tristan Bolmont, Florence Clavaguera, Melanie Meyer‐Luehmann, Martin C. Herzig, Rebecca Radde, Matthias Staufenbiel, Jada Lewis, Mike Hutton, Markus Tolnay, Mathias Jucker - American Journal Of Pathology 2007 cited by 271
- Aβ42 Is Essential for Parenchymal and Vascular Amyloid Deposition in Mice
Authors: Eileen McGowan, Fiona Pickford, Jungsu Kim, Luisa Onstead, Jason L. Eriksen, Cindy Yu, Lisa Skipper, Michael P. Murphy, J. David Beard, Pritam Das, Karen Jansen, Michael W. DeLucia, Wen-Lang Lin, Georgia Dolios, Rong Wang, Christopher B. Eckman, Dennis W. Dickson, Mike Hutton, John Hardy, Todd E. Golde - Neuron 2005 cited by 558
- Novel Mutations in TARDBP (TDP-43) in Patients with Familial Amyotrophic Lateral Sclerosis
Authors: Nicola J. Rutherford, Yong‐Jie Zhang, Matt Baker, Jennifer Gass, NiCole A. Finch, Yafei Xu, Heather Stewart, Brendan Kelley, Karen M. Kuntz, Richard Crook, Jemeen Sreedharan, Caroline Vance, Eric J. Sorenson, Carol F. Lippa, Eileen H. Bigio, Daniel H. Geschwind, David S. Knopman, Hiroshi Mitsumoto, Ronald C. Petersen, Neil R. Cashman, Mike Hutton, Christopher E. Shaw, Khrista Boylan, Bradley F. Boeve, Neill R. Graff‐Radford, Zbigniew K. Wszołek, Richard J. Caselli, Dennis W. Dickson, Ian R. Mackenzie, Leonard Petrucelli, Rosa Rademakers - PLoS Genetics 2008 cited by 463
- A variant of Alzheimer's disease with spastic paraparesis and unusual plaques due to deletion of exon 9 of presenilin 1
Authors: Richard Crook, Auli Verkkoniemi, Jordi Pérez‐Tur, Nitin D. Mehta, Matt Baker, Henry Houlden, Matthew J. Farrer, Mike Hutton, Sarah Lincoln, John Hardy, Katrina Gwinn, Mirja Somer, Anders Paetau, Hannu Kalimo, Raija Ylikoski, Minna Pöyhönen, Steve Kucera, Matti Haltia - Nature Medicine 1998 cited by 349
- Genetic dissection of Alzheimer's disease and related dementias: amyloid and its relationship to tau
Authors: John Hardy, Karen Duff, Katrina Gwinn Hardy, Jordi Pérez‐Tur, Mike Hutton - Nature Neuroscience 1998 cited by 344
- Improving Awareness Could Transform Outcomes in Degenerative Cervical Myelopathy [AO Spine RECODE-DCM Research Priority Number 1]
Authors: Benjamin M. Davies, Oliver Mowforth, Helen Wood, Zahabiya Karimi, Iwan Sadler, Lindsay Tetreault, Jamie Milligan, Jamie Wilson, Sukhvinder Kalsi‐Ryan, Julio C. Furlan, Yoshiharu Kawaguchi, Manabu Ito, Carl Moritz Zipser, Timothy F. Boerger, Alexander R. Vaccaro, Rory K. J. Murphy, Mike Hutton, Ricardo Rodrigues‐Pinto, Paul Aarne Koljonen, James S. Harrop, Bizhan Aarabi, Vafa Rahimi‐Movaghar, Shekar N. Kurpad, James D. Guest, Jefferson R. Wilson, Brian K. Kwon, Mark Kotter, Michael G. Fehlings - Global Spine Journal 2022 cited by 50
- Accumulation of Pathological Tau Species and Memory Loss in a Conditional Model of Tauopathy
Authors: Zdenek Berger, Hanno M. Roder, Amanda Hanna, Aaron Carlson, Vijayaraghavan Rangachari, Mei Yue, Zbigniew K. Wszołek, Karen H. Ashe, Joshua A. Knight, Dennis W. Dickson, Cathy Andorfer, Terrone L. Rosenberry, Jada Lewis, Mike Hutton, Christopher Janus - Journal of Neuroscience 2007 cited by 487
- 5′ Splice Site Mutations in tau Associated with the Inherited Dementia FTDP-17 Affect a Stem-Loop Structure That Regulates Alternative Splicing of Exon 10
Authors: Andrew Grover, Henry Houlden, Matt Baker, Jennifer Adamson, Jada Lewis, Guy Prihar, Stuart Pickering‐Brown, Karen Duff, Mike Hutton - Journal of Biological Chemistry 1999 cited by 299
- Argyrophilic Grain Disease Is a Sporadic 4-Repeat Tauopathy
Authors: Takashi Togo, Naruhiko Sahara, Shu-Hui Yen, Natalie Cookson, Takashi Ishizawa, Mike Hutton, Rohan de Silva, Andrew J. Lees, Dennis W. Dickson - Journal of Neuropathology & Experimental Neurology 2002 cited by 271
- Developing Therapeutic Approaches to Tau, Selected Kinases, and Related Neuronal Protein Targets
Authors: Virginia M.-Y. Lee, Kurt R. Brunden, Mike Hutton, John Q. Trojanowski - Cold Spring Harbor Perspectives in Medicine 2011 cited by 125
- Accelerated filament formation from tau protein with specific FTDP‐17 missense mutations
Authors: Parimala Nacharaju, Jada Lewis, Colin Easson, Samuel Yen, Samuel Yen, Jennifer Hackett, Mike Hutton, Shu-Hui Yen, Shu-Hui Yen - FEBS Letters 1999 cited by 289
- Prominent phenotypic variability associated with mutations in Progranulin
Authors: Brendan Kelley, Wael Haidar, Bradley F. Boeve, Matt Baker, Neill R. Graff‐Radford, Thomas A. Krefft, Andrew Frank, Clifford R. Jack, Maria Shiung, David S. Knopman, Keith A. Josephs, Sotirios A. Parashos, Rosa Rademakers, Mike Hutton, Stuart Pickering‐Brown, Jennifer Adamson, Karen M. Kuntz, Dennis W. Dickson, Joseph E. Parisi, Glenn E. Smith, Robert J. Ivnik, Ronald C. Petersen - Neurobiology of Aging 2007 cited by 182
- Matrix metalloproteinases in arthritic disease.
Authors: Gillian Murphy, Vera Knäuper, Susan J. Atkinson, George Butler, William English, Mike Hutton, Jan Olaf Stracke, Ian M. Clark - Arthritis Research 2002 cited by 306
- Phenotypic variability associated with progranulin haploinsufficiency in patients with the common 1477C→T (Arg493X) mutation: an international initiative
Authors: Rosa Rademakers, Matt Baker, Jennifer Gass, Jennifer Adamson, Edward D. Huey, Parastoo Momeni, Salvatore Spina, Giovanni Coppola, Anna M. Karydas, Heather Stewart, Nancy Johnson, Ging‐Yuek Robin Hsiung, Brendan Kelley, Karen M. Kuntz, Ellen J. Steinbart, Elisabeth McCarty Wood, Chang-En Yu, Keith A. Josephs, Eric J. Sorenson, Kyle Womack, Sandra Weıntraub, Stuart Pickering‐Brown, Peter R. Schofield, William S. Brooks, Vivianna M. Van Deerlin, Julie S. Snowden, Christopher M. Clark, Andrew Kertesz, Khrista Boylan, Bernardino Ghetti, David Neary, Gerard D Schellenberg, Thomas G. Beach, Marsel Mesulam, David Mann, Jordan Grafman, Ian R. Mackenzie, Howard Feldman, Thomas D. Bird, Ron Petersen, David S. Knopman, Bradley F. Boeve, Dan Geschwind, Bruce L. Miller, Zbigniew K. Wszołek, Carol F. Lippa, Eileen H. Bigio, Dennis W. Dickson, Neill R. Graff‐Radford, Mike Hutton - The Lancet Neurology 2007 cited by 218
- Multi-metric behavioral comparison of APPsw and P301L models for Alzheimer's Disease: linkage of poorer cognitive performance to tau pathology in forebrain
Authors: Gary W. Arendash, Jada Lewis, Ralph E. Leighty, Eileen McGowan, Jennifer R. Cracchiolo, Mike Hutton, Marcos F Garcia - Brain Research 2004 cited by 125
