Mitchell L. Shiffman
Active 1990–2025
- Also published as
- MITCHELL L. SHIFFMAN
- 141
- Papers
- 54,882
- Citations
- 104
- h-index
- 141
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine90.3%
- Biochemistry, Genetics and Molecular Biology4.8%
- Immunology and Microbiology1.9%
- Pharmacology, Toxicology and Pharmaceutics0.8%
- Neuroscience0.4%
- Agricultural and Biological Sciences0.3%
- Other1.5%
Topics
- Liver Disease Diagnosis and Treatment17.7%
- Hepatitis C virus research11.8%
- Hepatitis B Virus Studies6.5%
- Liver Disease and Transplantation6.4%
- Liver Diseases and Immunity3.8%
- Diet, Metabolism, and Disease3.1%
- Other50.7%
Coauthors
- Arun J. Sanyal35
- Velimir A. Luketic33
- Richard K. Sterling27
- Gregory T. Everson17
- Eric Lawitz16
- John G. McHutchison16
- Melissa J. Contos16
- Nezam H. Afdhal15
- Robert A. Fisher15
- Stuart C. Gordon15
- Zachary Goodman15
- K. Rajender Reddy14
- Kris V. Kowdley14
- Stephen A. Harrison13
- William M. Lee13
- Adrian M. Di Bisceglie12
- Anna S. Lok12
- Marc P. Posner12
- Paul J. Pockros12
- Robert P. Myers12
- Stefan Zeuzem12
- A. Scott Mills11
- Andrew J. Muir11
- Christopher L. Bowlus11
All papers
- A Placebo-Controlled Trial of Obeticholic Acid in Primary Biliary Cholangitis
Authors: Frederik Nevens, Pietro Andreoné, G. Mazzella, Simone I. Strasser, Christopher L. Bowlus, Pietro Invernizzi, Joost P.H. Drenth, Paul J. Pockros, Jarosław Reguła, Ulrich Beuers, Michael Trauner, David Jones, Annarosa Floreani, Simon Hohenester, Velimir A. Luketic, Mitchell L. Shiffman, Karel J. van Erpecum, Vı́ctor Vargas, Catherine Vincent, Gideon M. Hirschfield, Hemant Shah, Bettina E. Hansen, Keith D. Lindor, Hanns–Ulrich Marschall, Kris V. Kowdley, Roya Hooshmand-Rad, Tonya Marmon, Shawn Sheeron, Richard Pencek, Leigh MacConell, Mark Pruzanski, Д. А. Шапиро - New England Journal of Medicine 2016 cited by 1,108
- Selonsertib for patients with bridging fibrosis or compensated cirrhosis due to NASH: Results from randomized phase III STELLAR trials
Authors: Stephen A. Harrison, Vincent Wai‐Sun Wong, Takeshi Okanoue, Natalie Bzowej, Raj Vuppalanchi, Ziad Younes, Anita Kohli, Shiv Kumar Sarin, Stephen H. Caldwell, Naim Alkhouri, Mitchell L. Shiffman, Marianne Camargo, Georgia Li, Kathryn Kersey, Catherine Jia, Yanni Zhu, C. Stephen Djedjos, G. Mani Subramanian, Robert P. Myers, Nadege Gunn, Aasim Sheikh, Quentin M. Anstee, Manuel Romero‐Gómez, Michael Trauner, Zachary Goodman, Eric Lawitz, Zobair M. Younossi, Adrián Gadano, Marcelo Martins, Peter Angus, John Bate, Mark Danta, Jacob George, Alexander Hodge, Nickolas Kontorinis, S.A. Roberts, Santosh Sanagapalli, Richard Skoien, Alexander Thompson, Amany Zekry, Rudolf Stauber, Michael Trauner, Christophe Moreno, Hendrik Reynaert, Len Verbeke, Mário Reis Álvares‐da‐Silva, Edison Roberto Parise, Cláudia P. Oliveira, Roberta Chaves Araújo, Ana de Lourdes Candolo Martinelli, Meredith A. Borman, Natasha Chandok, Magdy Elkhashab, Hughie F. Fraser, Kelly Kaita, Mang Ma, Paul Marotta, Alnoor Ramji, Edward Tam, Eric M. Yoshida, Mark G. Swain, Giada Sebastiani, Denis Petrunia, Armand Abergel, Rodolphe Anty, Marc Bourlière, Jérôme Boursier, Christophe Bureau, Laurent Castéra, François Habersetzer, Christophe Hézode, V. de Lédinghen, Vincent Leroy, V. Loustaud‐Ratti, Philippe Mathurin, Stanislas Pol, Fabien Zoulim, Holger Hinrichsen, Patrick Ingiliz, Frank Lammert, Michael Manns, Jörn M. Schattenberg, Ingolf Schiefke, Christian Trautwein, Stefan Zeuzem, Aric J. Hui, K Li, Vincent Wai‐Sun Wong, Subrat Kumar Acharya, Abhijit Chowdhury, Ajay Duseja, Dharmesh Kapoor, Shrikant Mukewar, Shiv Kumar Sarin, Samir Shah, S. Shalimar, Ajit Sood, BV Tantry, Ziv Ben‐Ari, Helena Katchman and 540 more - Journal of Hepatology 2020 cited by 466
- Efficacy and Safety of Elafibranor in Primary Biliary Cholangitis
Authors: Kris V. Kowdley, Christopher L. Bowlus, Cynthia Levy, Ulus Salih Akarca, Mário Reis Álvares‐da‐Silva, Pietro Andreoné, Marco Arrese, Christophe Corpechot, Sven Francque, Michael A. Heneghan, Pietro Invernizzi, David Jones, Frederik C. Kruger, Eric Lawitz, Marlyn J. Mayo, Mitchell L. Shiffman, Mark G. Swain, José Miguel Valera, Vı́ctor Vargas, John M. Vierling, Alejandra Villamil, Carol Addy, Julie Dietrich, Jean‐Michel Germain, Sarah Mazain, Dragutin Rafailovic, Bachirou Taddé, Benjamin F. Miller, Jianfen Shu, Claudia O. Zein, Jörn M. Schattenberg - New England Journal of Medicine 2023 cited by 263
- Combination Therapies Including Cilofexor and Firsocostat for Bridging Fibrosis and Cirrhosis Attributable to NASH
Authors: Rohit Loomba, Mazen Noureddin, Kris V. Kowdley, Anita Kohli, Aasim Sheikh, Guy Neff, Bal Raj Bhandari, Nadege Gunn, Stephen H. Caldwell, Zachary Goodman, Ilan Wapinski, Murray B. Resnick, Andrew H. Beck, Dora Ding, Catherine Jia, Jen‐Chieh Chuang, Ryan S. Huss, Chuhan Chung, G. Mani Subramanian, Robert P. Myers, Keyur Patel, Brian B. Borg, Reem Ghalib, Heidi Kabler, John Poulos, Ziad Younes, Magdy Elkhashab, Tarek Hassanein, Rajalakshmi Iyer, Peter Ruane, Mitchell L. Shiffman, Simone I. Strasser, Vincent Wai‐Sun Wong, Naim Alkhouri, for the ATLAS Investigators - Hepatology 2020 cited by 278
- Effects of Belapectin, an Inhibitor of Galectin-3, in Patients With Nonalcoholic Steatohepatitis With Cirrhosis and Portal Hypertension
Authors: Naga Chalasani, Manal F. Abdelmalek, Guadalupe García–Tsao, Raj Vuppalanchi, Naim Alkhouri, Mary E. Rinella, Mazen Noureddin, Maxmillan Pyko, Mitchell L. Shiffman, Arun J. Sanyal, Adam Allgood, Harold Shlevin, R. G. Horton, Eliezer Zomer, William Irish, Zachary Goodman, Stephen A. Harrison, Peter G. Traber, Manal F. Abdelmalek, Luis A. Balart, Brian B. Borg, Naga Chalasani, Michael Charlton, Hari S. Conjeevaram, Michael Fuchs, Reem Ghalib, Pierre Gholam, Dina Halegoua‐De Marzio, Stephen A. Harrison, Christopher Jue, Nyingi Kemmer, Kris V. Kowdley, Michelle Lai, Eric Lawitz, Rohit Loomba, Mazen Noureddin, Angelo H. Paredes, Mary E. Rinella, Don C. Rockey, Miguel Rodriguez, Raymond A. Rubin, Michael Ryan, Arun J. Sanyal, Andrew Scanga, Thomas Sepe, Mitchell L. Shiffman, Mitchell L. Shiffman, Brent Tetri, Paul J. Thuluvath, Dawn M. Torres, John M. Vierling, Julia Wattacheril, Amanda Weiland, Donald L. Zogg - Gastroenterology 2019 cited by 344
- Nonalcoholic steatohepatitis: Association of insulin resistance and mitochondrial abnormalities
Authors: Arun J. Sanyal, Carol Campbell–Sargent, Faridoddin Mirshahi, William B. Rizzo, Melissa J. Contos, Richard K. Sterling, Velimir A. Luketic, Mitchell L. Shiffman, John N. Clore - Gastroenterology 2001 cited by 2,075
- Cilofexor, a Nonsteroidal FXR Agonist, in Patients With Noncirrhotic NASH: A Phase 2 Randomized Controlled Trial
Authors: Keyur Patel, Stephen A. Harrison, Magdy Elkhashab, James F. Trotter, Robert Herring, Sergio Rojter, Zeid Kayali, Vincent Wai‐Sun Wong, Susan Greenbloom, Saumya Jayakumar, Mitchell L. Shiffman, B. Freilich, Eric Lawitz, Edward Gane, Eliza Harting, Jun Xu, Andrew N. Billin, Chuhan Chung, C. Stephen Djedjos, G. Mani Subramanian, Robert P. Myers, Michael S. Middleton, Mary E. Rinella, Mazen Noureddin - Hepatology 2020 cited by 321
- Simtuzumab Is Ineffective for Patients With Bridging Fibrosis or Compensated Cirrhosis Caused by Nonalcoholic Steatohepatitis
Authors: Stephen A. Harrison, Manal F. Abdelmalek, Stephen H. Caldwell, Mitchell L. Shiffman, Anna Mae Diehl, Reem Ghalib, Eric Lawitz, Don C. Rockey, Raul Aguilar Schall, Catherine Jia, B. Mccolgan, John G. McHutchison, G. Mani Subramanian, Robert P. Myers, Zobair M. Younossi, Vlad Ratziu, Andrew J. Muir, Nezam H. Afdhal, Zachary Goodman, Jaime Bosch, Arun J. Sanyal - Gastroenterology 2018 cited by 372
- The Natural History of Advanced Fibrosis Due to Nonalcoholic Steatohepatitis: Data From the Simtuzumab Trials
Authors: Arun J. Sanyal, Stephen A. Harrison, Vlad Ratziu, Manal F. Abdelmalek, Anna Mae Diehl, Stephen H. Caldwell, Mitchell L. Shiffman, Raul Aguilar Schall, Catherine Jia, B. Mccolgan, C. Stephen Djedjos, John G. McHutchison, G. Mani Subramanian, Robert P. Myers, Zobair M. Younossi, Andrew J. Muir, Nezam H. Afdhal, Jaime Bosch, Zachary Goodman - Hepatology 2019 cited by 389
- The Nonsteroidal Farnesoid X Receptor Agonist Cilofexor (GS‐9674) Improves Markers of Cholestasis and Liver Injury in Patients With Primary Sclerosing Cholangitis
Authors: Michael Trauner, Aliya Gulamhusein, Bilal Hameed, Stephen H. Caldwell, Mitchell L. Shiffman, Charles Landis, Bertus Eksteen, Kosh Agarwal, Andrew J. Muir, Simon Rushbrook, Xiaomin Lu, Jun Xu, Jen‐Chieh Chuang, Andrew N. Billin, Georgia Li, Chuhan Chung, G. Mani Subramanian, Robert P. Myers, Christopher L. Bowlus, Kris V. Kowdley - Hepatology 2019 cited by 259
- Seladelpar efficacy and safety at 3 months in patients with primary biliary cholangitis: ENHANCE, a phase 3, randomized, placebo-controlled study
Authors: Gideon M. Hirschfield, Mitchell L. Shiffman, Aliya Gulamhusein, Kris V. Kowdley, John M. Vierling, Cynthia Levy, Andreas E. Kremer, Ehud Zigmond, Pietro Andreoné, Stuart C. Gordon, Christopher L. Bowlus, Eric Lawitz, Richard Aspinall, Daniel S. Pratt, K. L. Raikhelson, M.S. González-Huezo, Michael A. Heneghan, Sook‐Hyang Jeong, Alma Laura Ladrón De Guevara, Marlyn J. Mayo, George Ν. Dalekos, Joost P.H. Drenth, Ewa Janczewska, Barbara Leggett, Frederik Nevens, Vı́ctor Vargas, Eli Zuckerman, Christophe Corpechot, E Fassio, Holger Hinrichsen, Pietro Invernizzi, Palak Trivedi, Lisa Forman, David E.J. Jones, Stephen Ryder, Mark G. Swain, Alexandra Steinberg, Pol Boudes, Yun‐Jung Choi, Charles A. McWherter, ENHANCE Study Group* - Hepatology 2023 cited by 113
- Simtuzumab for Primary Sclerosing Cholangitis: Phase 2 Study Results With Insights on the Natural History of the Disease
Authors: Andrew J. Muir, Cynthia Levy, Harry L.A. Janssen, Aldo J. Montaño‐Loza, Mitchell L. Shiffman, Stephen H. Caldwell, Velimir A. Luketic, Dora Ding, Catherine Jia, B. Mccolgan, John G. McHutchison, G. Mani Subramanian, Robert P. Myers, Michael P. Manns, Roger W. Chapman, Nezam H. Afdhal, Zachary Goodman, Bertus Eksteen, Christopher L. Bowlus, for the GS‐US‐321‐0102 Investigators - Hepatology 2018 cited by 193
- Noninvasive Tests Accurately Identify Advanced Fibrosis due to NASH: Baseline Data From the STELLAR Trials
Authors: Quentin M. Anstee, Eric Lawitz, Naim Alkhouri, Vincent Wai‐Sun Wong, Manuel Romero‐Gómez, Takeshi Okanoue, Michael Trauner, Kathryn Kersey, Georgia Li, Ling Han, Catherine Jia, Lulu Wang, Guang Chen, G. Mani Subramanian, Robert P. Myers, C. Stephen Djedjos, Anita Kohli, Natalie Bzowej, Ziad Younes, Shiv Kumar Sarin, Mitchell L. Shiffman, Stephen A. Harrison, Nezam H. Afdhal, Zachary Goodman, Zobair M. Younossi - Hepatology 2019 cited by 266
- Seladelpar (MBX-8025), a selective PPAR-δ agonist, in patients with primary biliary cholangitis with an inadequate response to ursodeoxycholic acid: a double-blind, randomised, placebo-controlled, phase 2, proof-of-concept study
Authors: David Jones, Pol Boudes, Mark G. Swain, Christopher L. Bowlus, Michael Galambos, Bruce R. Bacon, Yvonne Döerffel, Norman Gitlin, Stuart C. Gordon, Joseph A. Odin, David Sheridan, M A Wörns, Virginia Clark, Linsey Corless, Heinz Hartmann, Mark Jonas, Andreas E. Kremer, George Mells, Peter Buggisch, B. Freilich, Cynthia Levy, John M. Vierling, David Bernstein, Marek Hartleb, Ewa Janczewska, Fedja A. Rochling, Hemant Shah, Mitchell L. Shiffman, John H. Smith, Yun‐Jung Choi, Alexandra Steinberg, Mónika Varga, Harinder Chera, Robert L. Martin, Charles A. McWherter, Gideon M. Hirschfield - The Lancet. Gastroenterology & hepatology 2017 cited by 186
- Clinical and Histologic Spectrum of Nonalcoholic Fatty Liver Disease Associated With Normal Alt Values
Authors: P MOFRAD, Melissa J. Contos, Mahmadul Haque, Carol Sargeant, Robert A. Fisher, Velimir A. Luketic, Richard K. Sterling, Mitchell L. Shiffman, Richard T. Stravitz, Arun J. Sanyal - Hepatology 2003 cited by 1,198
- Randomized placebo-controlled trial of emricasan for non-alcoholic steatohepatitis-related cirrhosis with severe portal hypertension
Authors: Guadalupe García–Tsao, Jaime Bosch, Zeid Kayali, Stephen A. Harrison, Manal F. Abdelmalek, Eric Lawitz, Sanjaya K. Satapathy, Marwan Ghabril, Mitchell L. Shiffman, Ziad Younes, Paul J. Thuluvath, Annalisa Berzigotti, Agustı́n Albillos, James M. Robinson, David Hagerty, Jean L. Chan, Arun J. Sanyal, Manal F. Abdelmalek, K.R. Bhamidimarri, Brian B. Borg, Stephen H. Caldwell, Jonathan M. Fenkel, B. Freilich, Michael Fuchs, Marwan Ghabril, R. Ghalib, Stevan A. Gonzalez, Sonya G. Gordon, Bilal Hameed, Stephen A. Harrison, Zeid Kayali, Nyingi Kemmer, Kevin Korenblat, Ming‐Zong Lai, Charles Landis, E.J. Lawitz, William M. Lee, Steven D. Lidofsky, Edward Mena, Mazen Noureddin, Angelo H. Paredes, Nikolaos Pyrsopoulos, K. Rajender Reddy, M. Rinella, Don C. Rockey, Manuel Rodríguez, Michele B. Ryan, Souvik Sarkar, Sanjaya K. Satapathy, Andrew Scanga, Mitchell L. Shiffman, Mohammad Shadab Siddiqui, Douglas A. Simonetto, Wing‐Kin Syn, Paul J. Thuluvath, Ramesh Vemulapalli, John M. Vierling, Ziad Younes, Agustı́n Albillos, Juan Arenas Ruiz-Tapiador, Salvador Augustín, José Luís Calleja, J. Crespo Garcia, L. García Buey, Juan Carlos García‐Pagán, Càndid Villanueva, C. Bureau, N. Carbonell, Valériane Leroy, Pierre‐Emmanuel Rautou, HS Heinzow, Ingolf Schiefke, Alexander Zipprich, Annalisa Berzigotti, Beat Muellhaupt - Journal of Hepatology 2019 cited by 156
- A phase II, randomized, open-label, 52-week study of seladelpar in patients with primary biliary cholangitis
Authors: Christopher L. Bowlus, Michael Galambos, Richard Aspinall, Gideon M. Hirschfield, David E.J. Jones, Yvonne Dörffel, Stuart C. Gordon, Stephen A. Harrison, Andreas E. Kremer, Marlyn J. Mayo, Paul J. Thuluvath, Cynthia Levy, Mark G. Swain, Guy Neff, David Sheridan, Carmen Stanca, Christoph P. Berg, Aparna Goel, Mitchell L. Shiffman, John M. Vierling, Pol Boudes, Alexandra Steinberg, Yun‐Jung Choi, Charles A. McWherter - Journal of Hepatology 2022 cited by 79
- Long-term efficacy and safety of obeticholic acid for patients with primary biliary cholangitis: 3-year results of an international open-label extension study
Authors: Michael Trauner, Frederik Nevens, Mitchell L. Shiffman, Joost P.H. Drenth, Christopher L. Bowlus, Vı́ctor Vargas, Pietro Andreoné, Gideon M. Hirschfield, Richard Pencek, Elizabeth Smoot Malecha, Leigh MacConell, Д. А. Шапиро - The Lancet. Gastroenterology & hepatology 2019 cited by 176
- Diagnosis and Management of Primary Biliary Cholangitis
Authors: Zobair M. Younossi, David Bernstein, Mitchell L. Shiffman, Paul Y. Kwo, W. Ray Kim, Kris V. Kowdley, Ira M. Jacobson - The American Journal of Gastroenterology 2018 cited by 209
- Complication Rate of Percutaneous Liver Biopsies Among Persons With Advanced Chronic Liver Disease in the HALT-C Trial
Authors: Leonard B. Seeff, Gregory T. Everson, Timothy R. Morgan, Teresa M. Curto, William M. Lee, Marc G. Ghany, Mitchell L. Shiffman, Robert J. Fontana, Adrian M. Di Bisceglie, Herbert L. Bonkovsky, Jules L. Dienstag - Clinical Gastroenterology and Hepatology 2010 cited by 466
- Tenofovir Disoproxil Fumarate versus Adefovir Dipivoxil for Chronic Hepatitis B
Authors: Patrick Marcellin, E. Jenny Heathcote, Marı́a Buti, Ed Gane, Robert A. de Man, Zahary Krastev, G. Germanidis, Sam S. Lee, Robert Flisiak, Kelly Kaita, Michael P. Manns, Iskren Kotzev, К. Tchernev, Peter Buggisch, Frank Weilert, Oya Ovung Kurdas, Mitchell L. Shiffman, Huy N. Trinh, M. Kay Washington, J. Sorbel, Jane Anderson, Andrea Snow‐Lampart, Elsa Mondou, Joe Quinn, Franck Rousseau - New England Journal of Medicine 2008 cited by 1,179
- Similarities and differences in outcomes of cirrhosis due to nonalcoholic steatohepatitis and hepatitis C†
Authors: Arun J. Sanyal, Colin Banas, Carol Sargeant, Velimir A. Luketic, Richard K. Sterling, Richard T. Stravitz, Mitchell L. Shiffman, Douglas M. Heuman, Adrian Coterrell, Robert A. Fisher, Melissa J. Contos, A. Scott Mills - Hepatology 2006 cited by 517
- Role of Noninvasive Tests in Clinical Gastroenterology Practices to Identify Patients With Nonalcoholic Steatohepatitis at High Risk of Adverse Outcomes: Expert Panel Recommendations
Authors: Zobair M. Younossi, Mazen Noureddin, David Bernstein, Paul Y. Kwo, Mark W. Russo, Mitchell L. Shiffman, Ziad Younes, Manal F. Abdelmalek - The American Journal of Gastroenterology 2020 cited by 104
- Emricasan to prevent new decompensation in patients with NASH-related decompensated cirrhosis
Authors: Catherine Frenette, Zeid Kayali, Edward Mena, Parvez Mantry, Kathryn Jean Lucas, Guy Neff, Miguel Rodriguez, Paul J. Thuluvath, Ethan M. Weinberg, Bal Raj Bhandari, J. E. M. Robinson, Nicole M. Wedick, Jean L. Chan, David Hagerty, Kris V. Kowdley, Kathleen E. Corey, David Bernstein, Mazen Noureddin, Nyingi Kemmer, Andrew S. deLemos, Nikolaos Pyrsopoulos, William Lee, Marwan Ghabril, Andrew Scanga, Mark McKenzie, Eric Lawitz, Viviana Figueroa-Diaz, Douglas A. Simonetto, R. Todd Frederick, Kimberly Brown, George Therapondos, Aasim Sheikh, Danielle Brandman, Lance L. Stein, Victor Ankoma‐Sey, Kalyan Ram Bhamidimarri, Charles Landis, Brett E. Fortune, Hugo E. Vargas, Manal F. Abdelmalek, B. Freilich, Don C. Rockey, John M. Vierling, H. Tatum, Michael P. Curry, Mitchell L. Shiffman, Kiran Bambha, Reem Ghalib, Amy Stratton, Nadeem Anwar, Stephen H. Caldwell, Ayman Koteish, Mohammad Siddiqui, Sammy Saab, Nikunj Shah, Anita Kohli, Mary E. Rinella, Souvik Sarkar, Dawn M. Torres, Elizabeth C. Verna, Ravi Ravendhran, Justin Reynolds, Ray Thomason, Ray Kim, Fernando E. Membreno, Simona Jakab, Stevan A. Gonzalez, Andrew P. Keaveny, Jen‐Jung Pan, Satinder Gill, Jonathan Huang, James Strobel, Amanda Wieland, Giuseppe Morelli, Thomas Amankonah, Marina Roytman, W Schmidt, Gary A. Abrams, Bhaktasharan Patel - Journal of Hepatology 2020 cited by 61
