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Motoharu Seiki

Active 1982–2024

148
Papers
31,752
Citations
104
h-index
148
i10-index

Citations

Citations per year for Motoharu Seiki1983: 7 citations1984: 62 citations1985: 91 citations1986: 98 citations1987: 104 citations1988: 179 citations1989: 141 citations1990: 161 citations1991: 173 citations1992: 176 citations1993: 127 citations1994: 139 citations1995: 208 citations1996: 312 citations1997: 368 citations1998: 453 citations1999: 528 citations2000: 483 citations2001: 492 citations2002: 492 citations2003: 601 citations2004: 499 citations2005: 366 citations2006: 445 citations2007: 348 citations2008: 272 citations2009: 255 citations2010: 259 citations2011: 196 citations2012: 180 citations2013: 164 citations2014: 157 citations2015: 144 citations2016: 105 citations2017: 173 citations2018: 74 citations2019: 378 citations2020: 321 citations2021: 337 citations2022: 253 citations2023: 176 citations2024: 190 citations2025: 111 citations2026: 2 citations

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 2,690 citing papers, 32.9% of this breakdownJapan: 985 citing papers, 12.1% of this breakdownUnited Kingdom: 506 citing papers, 6.2% of this breakdownChina: 454 citing papers, 5.6% of this breakdownGermany: 432 citing papers, 5.3% of this breakdownFrance: 379 citing papers, 4.6% of this breakdownCanada: 282 citing papers, 3.5% of this breakdownItaly: 214 citing papers, 2.6% of this breakdownBelgium: 172 citing papers, 2.1% of this breakdownSpain: 167 citing papers, 2% of this breakdownSouth Korea: 150 citing papers, 1.8% of this breakdownAustralia: 148 citing papers, 1.8% of this breakdown
0%32.9%Other 19.5%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology51.9%
  • Medicine26.3%
  • Immunology and Microbiology16.2%
  • Neuroscience2.1%
  • Agricultural and Biological Sciences0.8%
  • Materials Science0.5%
  • Other2.2%

Topics

  • Protease and Inhibitor Mechanisms10.7%
  • Peptidase Inhibition and Analysis5.7%
  • Cell Adhesion Molecules Research4.8%
  • T-cell and Retrovirus Studies3.9%
  • Animal Disease Management and Epidemiology3.1%
  • Vector-Borne Animal Diseases3%
  • Other68.8%

Coauthors

All papers

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  1. Cortactin promotes exosome secretion by controlling branched actin dynamics

    Authors: Seema Sinha, Daisuke Hoshino, Nan Hyung Hong, Kellye C. Kirkbride, Nathan E. Grega‐Larson, Motoharu Seiki, Matthew J. Tyska, Alissa M. Weaver - The Journal of Cell Biology 2016 cited by 326

  2. MT1-MMP-Dependent Control of Skeletal Stem Cell Commitment via a β1-Integrin/YAP/TAZ Signaling Axis

    Authors: Yi Tang, R. Grant Rowe, Elliot L. Botvinick, Abhishek Kurup, Andrew J. Putnam, Motoharu Seiki, Valerie M. Weaver, Evan T. Keller, Steven A. Goldstein, Jinlu Dai, Dana L. Begun, Thomas L. Saunders, Stephen J. Weiss - Developmental Cell 2013 cited by 260

  3. A matrix metalloproteinase expressed on the surface of invasive tumour cells

    Authors: Hiroshi Sato, Takahisa Takino, Yasunori Okada, Jian Cao, Akira Shinagawa, Etsuhide Yamamoto, Motoharu Seiki - Nature 1994 cited by 2,568

  4. The Membrane-Anchored MMP Inhibitor RECK Is a Key Regulator of Extracellular Matrix Integrity and Angiogenesis

    Authors: Junseo Oh, Rei Takahashi, Shunya Kondo, Akira Mizoguchi, Eijiro Adachi, Regina Maki Sasahara, Sachiko Nishimura, Yukio Imamura, Hitoshi Kitayama, David B. Alexander, Chizuka Idé, Thomas P. Horan, Tsutomu Arakawa, Hisahito Yoshida, Shin‐Ichi Nishikawa, Yoshifumi Itoh, Motoharu Seiki, Shigeyoshi Itohara, Chiaki Takahashi, Makoto Noda - Cell 2001 cited by 715

  5. Membrane Type 1 Matrix Metalloproteinase Digests Interstitial Collagens and Other Extracellular Matrix Macromolecules

    Authors: Eiko Ohuchi, Kazushi Imai, Yutaka Fujii, Hiroshi Sato, Motoharu Seiki, Yasunori Okada - Journal of Biological Chemistry 1997 cited by 936

  6. Turnover of Focal Adhesions and Cancer Cell Migration

    Authors: Makoto Nagano, Daisuke Hoshino, Naohiko Koshikawa, Toshifumi Akizawa, Motoharu Seiki - International Journal of Cell Biology 2012 cited by 284

  7. Membrane-Type 1 Matrix Metalloproteinase Cleaves Cd44 and Promotes Cell Migration

    Authors: Masahiro Kajita, Yoshifumi Itoh, Tadashige Chiba, Hidetoshi Mori, Akiko Okada, Hiroaki Kinoh, Motoharu Seiki - The Journal of Cell Biology 2001 cited by 736

  8. Endothelial MT1‐MMP targeting limits intussusceptive angiogenesis and colitis via TSP1/nitric oxide axis

    Authors: Sergio Esteban, Cristina Clemente, Agnieszka Kozioł, Pilar Gonzalo, Cristina Rius, Fernando Martínez, Pablo M. Linares, María Chaparro, Ana Urzainqui, Vicente Andrés, Motoharu Seiki, Javier P. Gisbert, Alicia G. Arroyo - EMBO Molecular Medicine 2019 cited by 49

  9. MT1‐MMP: A potent modifier of pericellular microenvironment

    Authors: Yoshifumi Itoh, Motoharu Seiki - Journal of Cellular Physiology 2005 cited by 490

  10. Homophilic complex formation of MT1‐MMP facilitates proMMP‐2 activation on the cell surface and promotes tumor cell invasion

    Authors: Yoshifumi Itoh, Akiko Takamura, Noriko Ito, Yoshiro Maru, Hiroshi Sato, Naoko Suenaga, Takanori Aoki, Motoharu Seiki - The EMBO Journal 2001 cited by 394

  11. Metalloproteinase-Dependent and TMPRSS2-Independent Cell Surface Entry Pathway of SARS-CoV-2 Requires the Furin Cleavage Site and the S2 Domain of Spike Protein

    Authors: Mizuki Yamamoto, Jin Gohda, Ayako Kobayashi, Keiko Tomita, Youko Hirayama, Naohiko Koshikawa, Motoharu Seiki, Kentaro Semba, Tetsu Akiyama, Yasushi Kawaguchi, Jun‐ichiro Inoue - mBio 2022 cited by 49

  12. EXOSC9 depletion attenuates P-body formation, stress resistance, and tumorigenicity of cancer cells

    Authors: Seiko Yoshino, Yusuke Matsui, Yuya Fukui, Masahide Seki, Kiyoshi Yamaguchi, Akane Kanamori, Yurika Saitoh, Teppei Shimamura, Yutaka Suzuki, Yoichi Furukawa, Shuichi Kaneko, Motoharu Seiki, Yoshinori Murakami, Jun‐ichiro Inoue, Takeharu Sakamoto - Scientific Reports 2020 cited by 31

  13. CD44 directs membrane‐type 1 matrix metalloproteinase to lamellipodia by associating with its hemopexin‐like domain

    Authors: Hidetoshi Mori, Taizo Tomari, Naohiko Koshikawa, Masahiro Kajita, Yoshifumi Itoh, Hiroshi Sato, Hideaki Tojo, Ikuo Yana, Motoharu Seiki - The EMBO Journal 2002 cited by 331

  14. Negative Regulation of Osteoclastogenesis by Ectodomain Shedding of Receptor Activator of NF-κB Ligand

    Authors: Atsuhiko Hikita, Ikuo Yana, Hidetoshi Wakeyama, Masaki Nakamura, Yuho Kadono, Yasushi Oshima, Kozo Nakamura, Motoharu Seiki, Sakae Tanaka - Journal of Biological Chemistry 2006 cited by 232

  15. Crosstalk between neovessels and mural cells directs the site-specific expression of MT1-MMP to endothelial tip cells

    Authors: Ikuo Yana, Hiroshi Sagara, Satoshi Τακακι, Kiyoshi Takatsu, Kenji Nakamura, Kazuki Nakao, Motoya Katsuki, Shun-ichiro Taniguchi, Takanori Aoki, Hiroshi Sato, Stephen J. Weiss, Motoharu Seiki - Journal of Cell Science 2007 cited by 180

  16. Cell Surface Collagenolysis Requires Homodimerization of the Membrane-bound Collagenase MT1-MMP

    Authors: Yoshifumi Itoh, Noriko Ito, Hideaki Nagase, Richard D. Evans, Sarah Bird, Motoharu Seiki - Molecular Biology of the Cell 2006 cited by 108

  17. Tetraspanin CD63 promotes targeting and lysosomal proteolysis of membrane-type 1 matrix metalloproteinase

    Authors: Takahisa Takino, Hisashi Miyamori, Noriko Kawaguchi, Takamasa Uekita, Motoharu Seiki, Hiroshi Sato - Biochemical and Biophysical Research Communications 2003 cited by 97

  18. v-Src activates the expression of 92-kDa type IV collagenase gene through the AP-1 site and the GT box homologous to retinoblastoma control elements. A mechanism regulating gene expression independent of that by inflammatory cytokines.

    Authors: Hiroshi Sato, Makiko Kita, Motoharu Seiki - Journal of Biological Chemistry 1993 cited by 291

  19. Significant correlation of monocyte chemoattractant protein-1 expression with neovascularization and progression of breast carcinoma

    Authors: Hisashi Saji, Morio Koike, Takao Yamori, Shigehira Saji, Motoharu Seiki, Kouji Matsushima, Masakazu Toi - Cancer 2001 cited by 286

  20. Dual expression of matrix metalloproteinase-2 and membrane-type 1-matrix metalloproteinase in fibrotic human livers

    Authors: Takeshi Takahara, Kei Furui, Yutaka Yata, Bilian Jin, Li Ping Zhang, Shuji Nambu, Hiroshi Sato, Motoharu Seiki, Ayako Watanabe - Hepatology 1997 cited by 178

  21. Membrane type 1 matrix metalloproteinase is a crucial promoter of synovial invasion in human rheumatoid arthritis

    Authors: Mary-Clare Miller, Hugh B. Manning, Abhilash Jain, Linda Troeberg, Jayesh Dudhia, David W. Essex, Ann Sandison, Motoharu Seiki, Jagdeep Nanchahal, Hideaki Nagase, Yoshifumi Itoh - Arthritis & Rheumatism 2009 cited by 134

  22. Transmembrane/cytoplasmic, rather than catalytic, domains of Mmp14 signal to MAPK activation and mammary branching morphogenesis via binding to integrin β1

    Authors: Hidetoshi Mori, Alvin Lo, Jamie L. Inman, Jordi Alcaraz, Cyrus M. Ghajar, Joni D. Mott, Celeste M. Nelson, Connie S. Chen, Hui Zhang, Jamie L. Bascom, Motoharu Seiki, Mina J. Bissell - Development 2012 cited by 105

  23. Novel LAMC2 fusion protein has tumor‐promoting properties in ovarian carcinoma

    Authors: Daisuke Hoshino, Hisamori Kato, Kazuhiro Fukumura, Akila Mayeda, Yohei Miyagi, Motoharu Seiki, Naohiko Koshikawa - Cancer Science 2021 cited by 25

  24. Monoclonal integration of human T-cell leukemia provirus in all primary tumors of adult T-cell leukemia suggests causative role of human T-cell leukemia virus in the disease.

    Authors: Minoru Yoshida, Motoharu Seiki, Kazunari Yamaguchi, Kiyoshi Takatsuki - National Academy of Sciences, Proceedings of the National Academy of Sciences 1984 cited by 898